{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:49:40Z","timestamp":1790088580887,"version":"4.0.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.hrthm.2021.06.1189","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T03:30:19Z","timestamp":1624678219000},"page":"1772-1779","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Safety, efficacy, and monitoring of bipolar radiofrequency ablation in beating myopathic human and healthy swine hearts"],"prefix":"10.1016","volume":"18","author":[{"given":"Abhishek","family":"Bhaskaran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Niri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Ali","family":"Azam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-5375","authenticated-orcid":false,"given":"Sachin","family":"Nayyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreu","family":"Porta-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Mass\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arulalan","family":"Veluppillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beibei","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick F.H.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumaraswamy","family":"Nanthakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2021.06.1189_bib1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/jce.12835","article-title":"Lesion size and safety comparison between the novel flex tip on the FlexAbility ablation catheter and the solid tips on the ThermoCool and ThermoCool SF ablation catheters","volume":"27","author":"Winterfield","year":"2016","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/europace\/euz341","article-title":"Endocardial ventricular pulsed field ablation: a proof-of-concept preclinical evaluation","volume":"22","author":"Koruth","year":"2020","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib3","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.hrthm.2020.04.034","article-title":"Bipolar ablation for intramural ventricular tachycardia substrate: ready for prime time?","volume":"17","author":"Liang","year":"2020","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib5","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1016\/j.hrthm.2020.06.025","article-title":"Bipolar radiofrequency ablation for ventricular tachycardias originating from the interventricular septum: safety and efficacy in a pilot cohort study","volume":"17","author":"Della Bella","year":"2020","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib6","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/pace.13907","article-title":"Trans-myocardial bipolar electrogram: a strategy for mapping and determining efficacy of bipolar ablation of deep foci","volume":"43","author":"Bokhari","year":"2020","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib7","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/j.hrthm.2012.08.001","article-title":"Bipolar irrigated radiofrequency ablation: a therapeutic option for refractory intramural atrial and ventricular tachycardia circuits","volume":"9","author":"Koruth","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib8","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1016\/j.hrthm.2016.07.011","article-title":"Clinical and biophysical evaluation of variable bipolar configurations during radiofrequency ablation for treatment of ventricular arrhythmias","volume":"13","author":"Nguyen","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib9","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.hrthm.2020.04.028","article-title":"Acute and long-term results of bipolar radiofrequency catheter ablation of refractory ventricular arrhythmias of deep intramural origin","volume":"17","author":"Igarashi","year":"2020","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib10","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.hroo.2020.06.006","article-title":"Bipolar ablation\u2019s unique paradigm: duration and power as respectively distinct primary determinants of transmurality and steam pop formation","volume":"1","author":"John","year":"2020","journal-title":"Heart Rhythm O2"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib11","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.hrthm.2020.04.029","article-title":"Anatomical approach with bipolar ablation between the left pulmonic cusp and the left ventricular outflow tract for left ventricular summit arrhythmias","volume":"17","author":"Futyma","year":"2020","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib12","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1111\/jce.12460","article-title":"Bipolar radiofrequency catheter ablation for refractory ventricular outflow tract arrhythmias","volume":"25","author":"Teh","year":"2014","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib13","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.hrcr.2019.06.002","article-title":"Bipolar ablation with half normal saline for deep intramural outflow tract premature ventricular contraction","volume":"5","author":"Enriquez","year":"2019","journal-title":"HeartRhythm Case Rep"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib14","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/jce.12893","article-title":"Circuit impedance could be a crucial factor influencing radiofrequency ablation efficacy and safety: a myocardial phantom study of the problem and its correction","volume":"27","author":"Bhaskaran","year":"2016","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib15","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1540-8159.1992.tb02897.x","article-title":"Impedance monitoring during radiofrequency catheter ablation in humans","volume":"15","author":"Harvey","year":"1992","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib16","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1540-8159.1994.tb01421.x","article-title":"In\u00a0vivo ventricular lesion growth in radiofrequency catheter ablation","volume":"17","author":"Simmers","year":"1994","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib17","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1111\/jce.14213","article-title":"Bipolar radiofrequency ablation creates different lesion characteristics compared to simultaneous unipolar ablation","volume":"30","author":"Nguyen","year":"2019","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib18","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1111\/jce.12682","article-title":"Effect of irrigant characteristics on lesion formation after radiofrequency energy delivery using ablation catheters with actively cooled tips","volume":"26","author":"Nguyen","year":"2015","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib19","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.jacep.2017.03.006","article-title":"Radiofrequency ablation using an open irrigated electrode cooled with half-normal saline","volume":"3","author":"Nguyen","year":"2017","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib20","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.jacep.2018.06.021","article-title":"Prospective multicenter experience with cooled radiofrequency ablation using high impedance irrigant to target deep myocardial substrate refractory to standard ablation","volume":"4","author":"Nguyen","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2021.06.1189_bib21","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.jacep.2020.02.013","article-title":"Evaluation of radiofrequency ablation irrigation type: in\u00a0vivo comparison of normal versus half-normal saline lesion characteristics","volume":"6","author":"Tschabrunn","year":"2020","journal-title":"JACC Clin Electrophysiol"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527121018026?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527121018026?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:54:51Z","timestamp":1761548091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527121018026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S1547527121018026"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2021.06.1189","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety, efficacy, and monitoring of bipolar radiofrequency ablation in beating myopathic human and healthy swine hearts","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2021.06.1189","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Heart Rhythm Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}