{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:24:17Z","timestamp":1783441457574,"version":"3.54.6"},"reference-count":11,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000028","name":"CIHR ICRH","doi-asserted-by":"publisher","award":["MOP142426"],"award-info":[{"award-number":["MOP142426"]}],"id":[{"id":"10.13039\/501100000028","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1-TR000445"],"award-info":[{"award-number":["UL1-TR000445"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007206","name":"Vanderbilt Institute for Clinical and Translational Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007206","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.hrthm.2021.12.030","type":"journal-article","created":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:06:09Z","timestamp":1644365169000},"page":"604-610","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Lower body muscle preactivation and tensing mitigate symptoms of initial orthostatic hypotension in young females"],"prefix":"10.1016","volume":"19","author":[{"given":"Nasia A.","family":"Sheikh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaun","family":"Ranada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dallan","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Kogut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate M.","family":"Bourne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana G.","family":"Jorge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy Y.","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Sheldon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek V.","family":"Exner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron A.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Runt\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish R.","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2021.12.030_bib1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jash.2015.02.006","article-title":"Detecting initial orthostatic hypotension: a novel approach","volume":"9","author":"McJunkin","year":"2015","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.hrthm.2021.12.030_bib2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1042\/CS20060091","article-title":"Initial orthostatic hypotension: review of a forgotten condition","volume":"112","author":"Wieling","year":"2007","journal-title":"Clin Sci"},{"key":"10.1016\/j.hrthm.2021.12.030_bib3","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijcard.2018.05.043","article-title":"Initial orthostatic hypotension among patients with unexplained syncope: an overlooked diagnosis?","volume":"271","author":"van Twist","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hrthm.2021.12.030_bib4","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/CS20070064","article-title":"Management of initial orthostatic hypotension: Lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squatting","volume":"113","author":"Krediet","year":"2007","journal-title":"Clin Sci"},{"key":"10.1016\/j.hrthm.2021.12.030_bib5","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1016\/j.jacc.2021.04.068","article-title":"Exploring the refractory period of an active stand in females with initial orthostatic","volume":"77","author":"Sheikh","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2021.12.030_bib6","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1161\/CIRCULATIONAHA.104.497594","article-title":"Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome","volume":"111","author":"Raj","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2021.12.030_bib7","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research Electronic Data Capture (REDCap): a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inf"},{"key":"10.1016\/j.hrthm.2021.12.030_bib8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s10286-016-0382-6","article-title":"Initial orthostatic hypotension in teenagers and young adults","volume":"26","author":"Van Wijnen","year":"2016","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.hrthm.2021.12.030_bib9","first-page":"69","article-title":"Physical countermeasures to increase orthostatic tolerance","volume":"277","author":"Van Dijk","year":"2014","journal-title":"J Intern Med"},{"key":"10.1016\/j.hrthm.2021.12.030_bib10","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.jpeds.2010.01.035","article-title":"Initial orthostatic hypotension in the young is attenuated by static handgrip","volume":"156","author":"Clarke","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.hrthm.2021.12.030_bib11","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s10286-008-0465-0","article-title":"Influence of age and gender on the occurrence and presentation of reflex syncope","volume":"18","author":"Romme","year":"2008","journal-title":"Clin Auton Res"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527121025248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527121025248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:55:42Z","timestamp":1761548142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527121025248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1547527121025248"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2021.12.030","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lower body muscle preactivation and tensing mitigate symptoms of initial orthostatic hypotension in young females","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2021.12.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Heart Rhythm Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}