{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:43:57Z","timestamp":1789663437192,"version":"4.0.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K08028"],"award-info":[{"award-number":["21K08028"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","heartrhythmjournal.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.hrthm.2024.04.101","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T09:14:46Z","timestamp":1714986886000},"page":"1787-1794","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Risk stratification for the occurrence of ventricular fibrillation in patients with early repolarization syndrome"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6419-1246","authenticated-orcid":false,"given":"Hiroshi","family":"Morita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saori","family":"Asada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Ueoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomofumi","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kawada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Nishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsuke","family":"Yuasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2024.04.101_bib1","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1056\/NEJMoa071968","article-title":"Sudden cardiac arrest associated with early repolarization","volume":"358","author":"Ha\u00efssaguerre","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2024.04.101_bib2","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.jacc.2013.05.054","article-title":"What do we know about the \"malignant form\" of early repolarization?","volume":"62","author":"Adler","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib3","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1056\/NEJMoa0907589","article-title":"Long-term outcome associated with early repolarization on electrocardiography","volume":"361","author":"Tikkanen","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2024.04.101_bib4","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1161\/CIRCULATIONAHA.110.014068","article-title":"Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcome","volume":"123","author":"Tikkanen","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.04.101_bib5","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/j.amjcard.2009.06.062","article-title":"Ability of terminal QRS notching to distinguish benign from malignant electrocardiographic forms of early repolarization","volume":"104","author":"Merchant","year":"2009","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib6","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.amjcard.2012.06.033","article-title":"Prevalence, prognosis, and identification of the malignant form of early repolarization pattern in a population-based study","volume":"110","author":"Rollin","year":"2012","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib7","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.jacc.2008.07.010","article-title":"J-point elevation in survivors of primary ventricular fibrillation and matched control subjects: incidence and clinical significance","volume":"52","author":"Rosso","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.hrthm.2011.09.012","article-title":"Distinguishing \"benign\" from \"malignant early repolarization\": the value of the ST-segment morphology","volume":"9","author":"Rosso","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib9","doi-asserted-by":"crossref","first-page":"e295","DOI":"10.1016\/j.hrthm.2016.05.024","article-title":"J-wave syndromes expert consensus conference report: emerging concepts and gaps in knowledge","volume":"13","author":"Antzelevitch","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1136\/heartjnl-2019-315007","article-title":"Long-term prognosis of patients with J-wave syndrome","volume":"106","author":"Kamakura","year":"2020","journal-title":"Heart"},{"key":"10.1016\/j.hrthm.2024.04.101_bib11","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.hrthm.2015.11.029","article-title":"J-wave duration and slope as potential tools to discriminate between benign and malignant early repolarization","volume":"13","author":"Cristoforetti","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib12","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.117.005214","article-title":"Tachycardia-induced J-wave changes in patients with and without idiopathic ventricular fibrillation","volume":"10","author":"Aizawa","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib13","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.hrthm.2015.11.020","article-title":"Benign vs. malignant inferolateral early repolarization: focus on the T wave","volume":"13","author":"Roten","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib14","doi-asserted-by":"crossref","DOI":"10.1111\/anec.12873","article-title":"Role of fragmented QRS and Shanghai score system in recurrence of ventricular fibrillation in patients with early repolarization syndrome","volume":"26","author":"Yonezu","year":"2021","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib15","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.jacc.2008.12.016","volume":"53","author":"Wagner","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib16","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/j.hrthm.2023.08.032","article-title":"Significance of left posterior extension of early repolarization in patients with J-wave syndrome","volume":"20","author":"Miyamoto","year":"2023","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib17","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1016\/j.hrthm.2023.09.007","article-title":"Early repolarization in the left posterior leads of the electrocardiogram: a new challenge for the existence of idiopathic ventricular fibrillation","volume":"20","author":"Huikuri","year":"2023","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib18","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.jacc.2008.10.044","article-title":"Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy","volume":"53","author":"Ha\u00efssaguerre","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib19","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.hrthm.2011.11.045","article-title":"Identification of high-risk syncope related to ventricular fibrillation in patients with Brugada syndrome","volume":"9","author":"Take","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib20","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.hrthm.2014.10.014","article-title":"Syncope in Brugada syndrome: prevalence, clinical significance, and clues from history taking to distinguish arrhythmic from nonarrhythmic causes","volume":"12","author":"Olde Nordkamp","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib21","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.hrthm.2022.03.1233","article-title":"Outcome of patients with early repolarization pattern and syncope","volume":"19","author":"Kamakura","year":"2022","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib22","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.hroo.2023.09.007","article-title":"Syncope and loss of consciousness after implantation of a cardioverter-defibrillator in patients with Brugada syndrome: prevalence and characteristics in long-term follow-up","volume":"4","author":"Asada","year":"2023","journal-title":"Heart Rhythm O2"},{"key":"10.1016\/j.hrthm.2024.04.101_bib23","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/europace\/eut355","article-title":"Estimation of the origin of ventricular outflow tract arrhythmia using synthesized right-sided chest leads","volume":"16","author":"Nakano","year":"2014","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2024.04.101_bib24","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.hrthm.2012.01.017","article-title":"Can fragmented QRS help in risk-stratifying patients with coronary artery disease and a relatively preserved ejection fraction?","volume":"9","author":"Das","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib25","series-title":"J Wave Syndromes: Brugada and Early Repolarization Syndromes","year":"2016"},{"key":"10.1016\/j.hrthm.2024.04.101_bib26","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0735-1097(01)01197-4","article-title":"Assessment of noninvasive markers in identifying patients at risk in the Brugada syndrome: insight into risk stratification","volume":"37","author":"Ikeda","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib27","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.hrthm.2024.01.016","article-title":"Clinical characteristics of electrical storm in patients with early repolarization syndrome","volume":"21","author":"Morita","year":"2024","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2024.04.101_bib28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/europace\/eur326","article-title":"Benign or malignant, early or delayed: the changing face of early repolarization","volume":"14","author":"Bastiaenen","year":"2012","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2024.04.101_bib29","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1093\/eurheartj\/ehp423","article-title":"Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome","volume":"31","author":"Nam","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2024.04.101_bib30","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.ijcard.2012.05.091","article-title":"Clinical characteristics and risk of arrhythmia recurrences in patients with idiopathic ventricular fibrillation associated with early repolarization","volume":"159","author":"Watanabe","year":"2012","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hrthm.2024.04.101_bib31","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/eurheartj\/ehv369","article-title":"Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome","volume":"37","author":"Kamakura","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2024.04.101_bib32","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1161\/01.CIR.41.6.899","article-title":"Total excitation of the isolated human heart","volume":"41","author":"Durrer","year":"1970","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.04.101_bib33","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1161\/CIRCULATIONAHA.122.061924","article-title":"Subepicardial cardiomyopathy: a disease underlying J-wave syndromes and idiopathic ventricular fibrillation","volume":"147","author":"Miles","year":"2023","journal-title":"Circulation"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527124025359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527124025359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T23:09:25Z","timestamp":1737328165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527124025359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S1547527124025359"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2024.04.101","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk stratification for the occurrence of ventricular fibrillation in patients with early repolarization syndrome","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2024.04.101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Heart Rhythm Society. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}