{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:45:52Z","timestamp":1779093952251,"version":"3.51.4"},"reference-count":26,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"am","delay-in-days":363,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.hrthm.2024.10.033","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T13:44:54Z","timestamp":1729604694000},"page":"1885-1891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Atrial flutter and sick sinus syndrome"],"prefix":"10.1016","volume":"22","author":[{"given":"Jean Jacques","family":"Noubiap","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Dewland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey E.","family":"Olgin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet J.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5197-7696","authenticated-orcid":false,"given":"Gregory M.","family":"Marcus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2024.10.033_bib1","doi-asserted-by":"crossref","first-page":"e143","DOI":"10.1161\/01.CIR.0000102938.55119.EC","article-title":"Cardiology patient pages. Sick sinus syndrome","volume":"108","author":"Gregoratos","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib2","first-page":"691","article-title":"Sick sinus syndrome: a review","volume":"87","author":"Semelka","year":"2013","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.hrthm.2024.10.033_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0002-9149(96)90394-X","article-title":"Survey of cardiac pacing and defibrillation in the United States in 1993","volume":"78","author":"Bernstein","year":"1996","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2024.10.033_bib4","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1161\/CIRCULATIONAHA.106.616011","article-title":"New insights into pacemaker activity: promoting understanding of sick sinus syndrome","volume":"115","author":"Dobrzynski","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib5","series-title":"Cardiac Electrophysiology","first-page":"490","article-title":"Atrial flutter: mechanisms, clinical features, and management","author":"Waldo","year":"2004"},{"key":"10.1016\/j.hrthm.2024.10.033_bib6","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1161\/01.CIR.92.7.1839","article-title":"Role of right atrial endocardial structures as barriers to conduction during human type I atrial flutter. Activation and entrainment mapping guided by intracardiac echocardiography","volume":"92","author":"Olgin","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0735-1097(99)00211-9","article-title":"Transverse conduction capabilities of the crista terminalis in patients with atrial flutter and atrial fibrillation","volume":"34","author":"Schumacher","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.10.033_bib8","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1161\/01.CIR.99.21.2771","article-title":"Rate-dependent conduction block of the crista terminalis in patients with typical atrial flutter: influence on evaluation of cavotricuspid isthmus conduction block","volume":"99","author":"Arenal","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib9","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1161\/01.CIR.52.2.208","article-title":"Sick sinus syndrome after surgery for congenital heart disease","volume":"52","author":"Greenwood","year":"1975","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib10","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1161\/01.CIR.0000121734.47409.AA","article-title":"Electrophysiological and electroanatomic characterization of the atria in sinus node disease: evidence of diffuse atrial remodeling","volume":"109","author":"Sanders","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib11","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.026028","article-title":"Progressive and simultaneous right and left atrial remodeling uncovered by a comprehensive magnetic resonance assessment in atrial fibrillation","volume":"11","author":"Gunturiz-Beltr\u00e1n","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hrthm.2024.10.033_bib12","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1161\/01.CIR.94.11.2953","article-title":"Pacing-induced chronic atrial fibrillation impairs sinus node function in dogs. Electrophysiological remodeling","volume":"94","author":"Elvan","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib13","first-page":"383","article-title":"Impaired sinus node function and global atrial conduction time after high rate atrial pacing in dogs","volume":"7","author":"Zupan","year":"2002","journal-title":"Cell Mol Biol Lett"},{"key":"10.1016\/j.hrthm.2024.10.033_bib14","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0002-8703(77)80070-7","article-title":"Pathology of sinoatrial node. Correlations with electrocardiographic findings in 111 patients","volume":"93","author":"Thery","year":"1977","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2024.10.033_bib15","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1046\/j.1540-8167.2002.00584.x","article-title":"Short-term rapid atrial pacing produces electrical remodeling of sinus node function in humans","volume":"13","author":"Hadian","year":"2002","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2024.10.033_bib16","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1161\/01.CIR.0000090685.13169.07","article-title":"Reverse remodeling of sinus node function after catheter ablation of atrial fibrillation in patients with prolonged sinus pauses","volume":"108","author":"Hocini","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib17","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/01.CIR.102.15.1807","article-title":"Electrical remodeling of the atria associated with paroxysmal and chronic atrial flutter","volume":"102","author":"Sparks","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2024.10.033_bib18","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1161\/CIRCRESAHA.121.319893","article-title":"Arrhythmias in female patients: incidence, presentation and management","volume":"130","author":"Zeitler","year":"2022","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2024.10.033_bib19","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/europace\/euab087","article-title":"A meta-analysis of clinical risk factors for stroke in anticoagulant-na\u00efve patients with atrial fibrillation","volume":"23","author":"Noubiap","year":"2021","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2024.10.033_bib20","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1136\/heartjnl-2019-315065","article-title":"Female sex as a risk factor for ischaemic stroke varies with age in patients with atrial fibrillation","volume":"106","author":"Wu","year":"2020","journal-title":"Heart"},{"key":"10.1016\/j.hrthm.2024.10.033_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109662","article-title":"Association of sick sinus syndrome with incident cardiovascular disease and mortality: the Atherosclerosis Risk in Communities study and Cardiovascular Health Study","volume":"9","author":"Alonso","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.hrthm.2024.10.033_bib22","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jacc.2014.03.056","article-title":"Incidence of and risk factors for sick sinus syndrome in the general population","volume":"64","author":"Jensen","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"suppl 1","key":"10.1016\/j.hrthm.2024.10.033_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/pds.2317","article-title":"A systematic review of validated methods for identifying atrial fibrillation using administrative data","volume":"21","author":"Jensen","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.hrthm.2024.10.033_bib24","article-title":"Validity of International Classification of Diseases, Tenth Revision, codes for atrial fibrillation\/flutter in critically ill patients with sepsis","volume":"43","author":"Persaud","year":"2024","journal-title":"Anaesth Crit Care Pain Med"},{"key":"10.1016\/j.hrthm.2024.10.033_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jacc.2016.10.048","article-title":"Alcohol abuse and cardiac disease","volume":"69","author":"Whitman","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2024.10.033_bib26","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1161\/CIRCULATIONAHA.113.002449","article-title":"Incident atrial fibrillation among Asians, Hispanics, blacks, and whites","volume":"128","author":"Dewland","year":"2013","journal-title":"Circulation"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527124034593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527124034593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T20:58:50Z","timestamp":1756933130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527124034593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S1547527124034593"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2024.10.033","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Atrial flutter and sick sinus syndrome","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2024.10.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Heart Rhythm Society. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}