{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T09:04:06Z","timestamp":1774256646035,"version":"3.50.1"},"reference-count":4,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.hrthm.2025.01.017","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T05:31:12Z","timestamp":1737178272000},"page":"e254-e256","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The effect of capsaicin-phenylephrine-caffeine formulation on tilt-induced syncope in patients with a history of vasovagal syncope or near-syncope"],"prefix":"10.1016","volume":"22","author":[{"given":"Mohamed H.","family":"Hamdan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Brignole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Michelet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Claude","family":"Deharo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9gis","family":"Guieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2025.01.017_bib1","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.jacc.2017.03.002","article-title":"2017 ACC\/AHA\/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"70","author":"Shen","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2025.01.017_bib2","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1161\/01.CIR.0000046228.97025.3A","article-title":"Coffee acutely increases sympathetic nerve activity and blood pressure independently of caffeine content: role of habitual versus nonhabitual drinking","volume":"106","author":"Corti","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2025.01.017_bib3","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1136\/heartjnl-2011-301411","article-title":"Adenosine plasma level and A2A adenosine receptor expression: correlation with laboratory tests in patients with neurally mediated syncope","volume":"98","author":"Deharo","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.hrthm.2025.01.017_bib4","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s40268-021-00378-9","article-title":"Safety, pharmacokinetic, and pharmacodynamic study of a sublingual formula for the treatment of vasovagal syncope","volume":"22","author":"Hutson","year":"2022","journal-title":"Drugs R D"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527125000864?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527125000864?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T08:22:34Z","timestamp":1774254154000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527125000864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1547527125000864"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2025.01.017","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of capsaicin-phenylephrine-caffeine formulation on tilt-induced syncope in patients with a history of vasovagal syncope or near-syncope","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2025.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of Heart Rhythm Society.","name":"copyright","label":"Copyright"}]}}