{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:16:43Z","timestamp":1790705803929,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,26]],"date-time":"2026-11-26T00:00:00Z","timestamp":1795651200000},"content-version":"am","delay-in-days":360,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP23K15119"],"award-info":[{"award-number":["JP23K15119"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K1609302"],"award-info":[{"award-number":["22K1609302"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007697","name":"Northern Advancement Center for Science and Technology","doi-asserted-by":"publisher","award":["7842001023"],"award-info":[{"award-number":["7842001023"]}],"id":[{"id":"10.13039\/501100007697","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008667","name":"SENSHIN Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008667","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015639","name":"Japan Cardiovascular Research Foundation","doi-asserted-by":"publisher","award":["PK6322059"],"award-info":[{"award-number":["PK6322059"]}],"id":[{"id":"10.13039\/100015639","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","award":["PK420950"],"award-info":[{"award-number":["PK420950"]}],"id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.hrthm.2025.08.011","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T23:25:41Z","timestamp":1754954741000},"page":"e1179-e1192","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Neuropeptide Y drives ventricular arrhythmogenesis in chronic ischemic heart failure via calcium mishandling"],"prefix":"10.1016","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5777-7813","authenticated-orcid":false,"given":"Jiro","family":"Koya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0480-7226","authenticated-orcid":false,"given":"Taro","family":"Temma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyuki","family":"Karube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zen-ichi","family":"Tanei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kawasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kintaro","family":"Shimano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daishiro","family":"Tatsuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Natsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahide","family":"Kadosaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Koya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoki","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiwamu","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumino","family":"Fujiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihisa","family":"Anzai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2025.08.011_bib1","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1056\/NEJMoa013474","article-title":"Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction","volume":"346","author":"Moss","year":"2002","journal-title":"N Engl J Med Mass Med Soc"},{"key":"10.1016\/j.hrthm.2025.08.011_bib2","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1056\/NEJMoa0901889","article-title":"Defibrillator implantation early after myocardial infarction","volume":"361","author":"Steinbeck","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2025.08.011_bib3","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1056\/NEJMoa043938","article-title":"Sudden death in patients with myocardial infarction and left ventricular dysfunction, heart failure, or both","volume":"352","author":"Solomon","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2025.08.011_bib4","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jacc.2004.09.076","article-title":"Antiarrhythmic effect of carvedilol after acute myocardial infarction: results of the carvedilol post-infarct Survival Control in Left ventricular Dysfunction (Capricorn) trial","volume":"45","author":"McMurray","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib5","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/S0140-6736(00)04560-8","article-title":"Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the Capricorn randomised trial","volume":"357","author":"Dargie","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.hrthm.2025.08.011_bib6","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1056\/NEJM199108293250905","article-title":"Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias","volume":"325","author":"Meredith","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2025.08.011_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1161\/01.RES.0000258172.74570.e6","article-title":"Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium\/calmodulin-dependent protein kinase","volume":"100","author":"Curran","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2025.08.011_bib8","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1016\/j.jacc.2018.02.056","article-title":"Propranolol versus metoprolol for treatment of electrical storm in patients with implantable cardioverter-defibrillator","volume":"71","author":"Chatzidou","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib9","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.1073\/pnas.79.18.5485","article-title":"Neuropeptide Y: complete amino acid sequence of the brain peptide","volume":"79","author":"Tatemoto","year":"1982","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.hrthm.2025.08.011_bib10","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.yjmcc.2004.11.001","article-title":"Neuropeptide Y rapidly enhances [Ca2+]I transients and Ca2+ sparks in adult rat ventricular myocytes through Y1 receptor and PLC activation","volume":"38","author":"Heredia Mdel","year":"2005","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib11","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1161\/CIRCEP.115.002927","article-title":"Suppression of early and late afterdepolarizations by heterozygous knockout of the Na+\/Ca2+ exchanger in a murine model","volume":"8","author":"B\u00f6geholz","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib12","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/s41569-019-0221-2","article-title":"The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies","volume":"16","author":"Herring","year":"2019","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib13","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.119.005890","article-title":"Brain-derived neurotrophic factor improves impaired fatty acid oxidation via the activation of adenosine monophosphate-activated protein kinase-\u0251 - proliferator-activated receptor-r Coactivator-1\u0251 signaling in skeletal muscle of mice with heart failure","volume":"14","author":"Matsumoto","year":"2021","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.hrthm.2025.08.011_bib14","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jacc.2018.12.064","article-title":"Autonomic nervous system dysfunction: JACC focus seminar","volume":"73","author":"Goldberger","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib15","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1161\/CIRCRESAHA.113.302549","article-title":"Role of the autonomic nervous system in modulating cardiac arrhythmias","volume":"114","author":"Shen","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2025.08.011_bib16","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1172\/JCI105113","article-title":"Cardiac norepinephrine stores in experimental heart failure in the dog","volume":"43","author":"Chidsey","year":"1964","journal-title":"J Clin Invest"},{"key":"10.1016\/j.hrthm.2025.08.011_bib17","doi-asserted-by":"crossref","first-page":"H2229","DOI":"10.1152\/ajpheart.00768.2003","article-title":"Infarction alters both the distribution and noradrenergic properties of cardiac sympathetic neurons","volume":"286","author":"Li","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib18","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1161\/01.RES.69.2.455","article-title":"Sympathetic stimulation-evoked overflow of norepinephrine and neuropeptide Y from the heart","volume":"69","author":"Warner","year":"1991","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2025.08.011_bib19","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1136\/heartjnl-2012-303443","article-title":"Relationship of plasma neuropeptide Y with angiographic, electrocardiographic and coronary physiology indices of reperfusion during ST elevation myocardial infarction","volume":"99","author":"Cuculi","year":"2013","journal-title":"Heart"},{"key":"10.1016\/j.hrthm.2025.08.011_bib20","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1475-097X.1986.tb00789.x","article-title":"Plasma neuropeptide Y-like immunoreactivity and catecholamines during various degrees of sympathetic activation in man","volume":"6","author":"Pernow","year":"1986","journal-title":"Clin Physiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib21","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1113\/JP285945","article-title":"Circulating noradrenaline leads to release of neuropeptide Y from cardiac sympathetic nerve terminals via activation of \u03b2-adrenergic receptors","volume":"603","author":"van Weperen","year":"2025","journal-title":"J Physiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib22","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1056\/NEJM198409273111303","article-title":"Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure","volume":"311","author":"Cohn","year":"1984","journal-title":"N Engl J Med Mass Med Soc"},{"key":"10.1016\/j.hrthm.2025.08.011_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.925692","article-title":"\u03b2-Adrenergic Receptor Desensitization\/Down-Regulation in Heart Failure: A Friend or Foe?","volume":"9","author":"Mahmood","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.hrthm.2025.08.011_bib24","doi-asserted-by":"crossref","first-page":"E3036","DOI":"10.1073\/pnas.1718211115","article-title":"Complex electrophysiological remodeling in postinfarction ischemic heart failure","volume":"115","author":"Hegyi","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.hrthm.2025.08.011_bib25","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.hrthm.2015.01.045","article-title":"Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: neuropeptide and morphologic changes","volume":"12","author":"Ajijola","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2025.08.011_bib26","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1001\/jamacardio.2019.4717","article-title":"Coronary sinus neuropeptide Y levels and adverse outcomes in patients with stable chronic heart failure","volume":"5","author":"Ajijola","year":"2020","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib27","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1093\/eurheartj\/ehz852","article-title":"The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade","volume":"41","author":"Kalla","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2025.08.011_bib28","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1172\/JCI117739","article-title":"Differential regulation of two types of intracellular calcium release channels during end-stage heart failure","volume":"95","author":"Go","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1016\/j.hrthm.2025.08.011_bib29","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.RES.0000194329.41863.89","article-title":"Ca2+\/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure","volume":"97","author":"Ai","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2025.08.011_bib30","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.pbiomolbio.2005.06.010","article-title":"The Ca 2+ leak paradox and rogue ryanodine receptors: SR Ca 2+ efflux theory and practice","volume":"90","author":"Sobie","year":"2006","journal-title":"Prog Biophys Mol Biol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib31","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.pharmthera.2009.03.006","article-title":"Ryanodine receptor-mediated arrhythmias and sudden cardiac death","volume":"123","author":"Blayney","year":"2009","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.hrthm.2025.08.011_bib32","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.yjmcc.2010.01.011","article-title":"Increased myofilament Ca2+-sensitivity and arrhythmia susceptibility","volume":"48","author":"Huke","year":"2010","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib33","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1161\/CIRCRESAHA.110.226845","article-title":"Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis","volume":"108","author":"Priori","year":"2011","journal-title":"Circ Res"},{"key":"10.1016\/j.hrthm.2025.08.011_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0108382","article-title":"Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin D signaling","volume":"9","author":"Choudhury","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.hrthm.2025.08.011_bib35","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/j.jacc.2009.01.065","article-title":"Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor","volume":"53","author":"Kobayashi","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib36","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1161\/01.CIR.103.1.140","article-title":"A Ca(2+)-dependent transgenic model of cardiac hypertrophy: a role for protein kinase Calpha","volume":"103","author":"Muth","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2025.08.011_bib37","article-title":"Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression","volume":"7","author":"Eden","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.hrthm.2025.08.011_bib38","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1172\/JCI31060","article-title":"Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure","volume":"117","author":"Nakayama","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.hrthm.2025.08.011_bib39","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.135519","article-title":"Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y","volume":"5","author":"Hoang","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.hrthm.2025.08.011_bib40","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/ejhf.3085","article-title":"Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes","volume":"26","author":"McDowell","year":"2024","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hrthm.2025.08.011_bib41","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.yjmcc.2010.08.022","article-title":"Effects of neuropeptide Y on collateral development in a swine model of chronic myocardial ischemia","volume":"49","author":"Robich","year":"2010","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib42","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.ymthe.2021.10.005","article-title":"Neuropeptide Y attenuates cardiac remodeling and deterioration of function following myocardial infarction","volume":"30","author":"Qin","year":"2022","journal-title":"Mol Ther"},{"key":"10.1016\/j.hrthm.2025.08.011_bib43","first-page":"H1727","article-title":"Positive and negative contractile effects of neuropeptide Y on ventricular cardiomyocytes","volume":"261","author":"Millar","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1016\/j.hrthm.2025.08.011_bib44","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1111\/j.1476-5381.1996.tb15560.x","article-title":"Effects of neuropeptide Y on L-type calcium current in guinea-pig ventricular myocytes","volume":"118","author":"Bryant","year":"1996","journal-title":"Br J Pharmacol"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527125027523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527125027523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T07:20:32Z","timestamp":1778397632000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527125027523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1547527125027523"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2025.08.011","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuropeptide Y drives ventricular arrhythmogenesis in chronic ischemic heart failure via calcium mishandling","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2025.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Heart Rhythm Society. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}