{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T05:24:51Z","timestamp":1793942691807,"version":"4.8.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003793","name":"The Swedish Heart Lung Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.hrthm.2026.03.1955","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T16:27:53Z","timestamp":1775579273000},"page":"1726-1731","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Estimation of atrial fibrillation burden as a function of monitoring time without atrial fibrillation"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2249-8220","authenticated-orcid":false,"given":"Linda S.","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albin","family":"Edegran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason G.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander P.","family":"Benz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taya","family":"Glotzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey S.","family":"Healey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Svennberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2026.03.1955_bib1","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euaf318","article-title":"Transforming atrial fibrillation management by targeting comorbidities and reducing atrial fibrillation burden: the 10th AFNET\/EHRA consensus conference","volume":"27","author":"Svennberg","year":"2025","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib2","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euaf019","article-title":"Atrial fibrillation burden in clinical practice, research, and technology development: a clinical consensus statement of the European Society of Cardiology Council on Stroke and the European Heart Rhythm Association","volume":"27","author":"Doehner","year":"2025","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib3","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1093\/eurheartj\/ehae373","article-title":"Atrial fibrillation burden: a new outcome predictor and therapeutic target","volume":"45","author":"Becher","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.jacc.2023.06.029","article-title":"Ablation to reduce atrial fibrillation burden and improve outcomes: JACC Review Topic of the Week","volume":"82","author":"Schwennesen","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib5","doi-asserted-by":"crossref","first-page":"e522","DOI":"10.1016\/j.hrthm.2025.03.1984","article-title":"Rethinking AF ablation success by integrating AF burden into time-to-event analysis: the burden-survival curve","volume":"22","author":"Duytschaever","year":"2025","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.hrthm.2026.01.017","article-title":"Burden-based outcomes after atrial fibrillation ablation: a 4-year continuous monitoring study","author":"Almorad","year":"2026","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib7","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1016\/j.jacc.2014.04.019","article-title":"Clinical classifications of atrial fibrillation poorly reflect its temporal persistence: insights from 1,195 patients continuously monitored with implantable devices","volume":"63","author":"Charitos","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1001\/jamacardio.2018.1176","article-title":"Association of burden of atrial fibrillation with risk of ischemic stroke in adults with paroxysmal atrial fibrillation: the KP-RHYTHM study","volume":"3","author":"Go","year":"2018","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib9","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/eurheartj\/ehad572","article-title":"Atrial fibrillation progression after cryoablation vs. radiofrequency ablation: the CIRCA-DOSE trial","volume":"45","author":"Andrade","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1161\/CIRCULATIONAHA.125.074485","article-title":"Pulsed field ablation of persistent atrial fibrillation with continuous electrocardiographic monitoring follow-up: ADVANTAGE AF phase 2","volume":"152","author":"Reddy","year":"2025","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1056\/NEJMoa2310234","article-title":"Apixaban for stroke prevention in subclinical atrial fibrillation","volume":"390","author":"Healey","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib12","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1161\/CIRCULATIONAHA.123.067512","article-title":"Direct oral anticoagulants for stroke prevention in patients with device-detected atrial fibrillation: A study-level meta-analysis of the NOAH-AFNET 6 and ARTESiA trials","volume":"149","author":"McIntyre","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib13","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1056\/NEJMoa2303062","article-title":"Anticoagulation with edoxaban in patients with atrial high-rate episodes","volume":"389","author":"Kirchhof","year":"2023","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/eurheartj\/ehu307","article-title":"Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES","volume":"36","author":"Vanassche","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1161\/CIRCULATIONAHA.121.056109","article-title":"Influence of monitoring strategy on assessment of ablation success and postablation atrial fibrillation burden assessment: implications for practice and clinical trial design","volume":"145","author":"Aguilar","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib16","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/eurheartj\/ehaf647","article-title":"Atrial fibrillation burden is underestimated by non-invasive monitoring: the CIRCA-DOSE trial","volume":"47","author":"Aguilar","year":"2026","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib17","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0140-6736(19)31721-0","article-title":"An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction","volume":"394","author":"Attia","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib18","doi-asserted-by":"crossref","DOI":"10.1111\/anec.13090","article-title":"Can 24 h of ambulatory ECG be used to triage patients to extended monitoring?","volume":"28","author":"Johnson","year":"2023","journal-title":"Ann Noninvas Electrocardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib19","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/s41591-025-03516-x","article-title":"Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography","volume":"31","author":"Johnson","year":"2025","journal-title":"Nat Med"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib20","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.123.034758","article-title":"Residual stroke risk among patients with atrial fibrillation prescribed oral anticoagulants: a patient-level meta-analysis from COMBINE AF","volume":"13","author":"Johnson","year":"2024","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib21","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/j.jacc.2024.08.019","article-title":"Effect of screening for undiagnosed atrial fibrillation on stroke prevention","volume":"84","author":"Lopes","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib22","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/S0140-6736(21)01698-6","article-title":"Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial","volume":"398","author":"Svendsen","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib23","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1161\/CIRCULATIONAHA.124.069903","article-title":"Risk of stroke or systemic embolism according to baseline frequency and duration of subclinical atrial fibrillation: insights from the ARTESiA trial","volume":"150","author":"McIntyre","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib24","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.jacc.2024.05.002","article-title":"Apixaban versus Aspirin According to CHA2DS2-VASc Score in subclinical atrial fibrillation: Insights from ARTESiA","volume":"84","author":"Lopes","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib25","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/s44325-025-00097-z","article-title":"What\u2019s the best way to leverage 31 million days of ECG data?","volume":"2","author":"Johnson","year":"2025","journal-title":"NPJ Cardiovasc Health"},{"key":"10.1016\/j.hrthm.2026.03.1955_bib26","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1093\/europace\/euv032","article-title":"The development of AF over time in patients with permanent pacemakers: objective assessment with pacemaker diagnostics demonstrates distinct patterns of AF","volume":"17","author":"Sugihara","year":"2015","journal-title":"Europace"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527126022381?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527126022381?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T04:37:58Z","timestamp":1793939878000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527126022381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1547527126022381"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2026.03.1955","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Estimation of atrial fibrillation burden as a function of monitoring time without atrial fibrillation","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2026.03.1955","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Heart Rhythm Society.","name":"copyright","label":"Copyright"}]}}