{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T20:07:47Z","timestamp":1648930067797},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","heartandlung.org","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart &amp; Lung"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.hrtlng.2018.05.008","type":"journal-article","created":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T13:13:12Z","timestamp":1527599592000},"page":"387-391","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["An evaluation of patient-specific characteristics on attainment of target sedation in an intensive care unit"],"prefix":"10.1016","volume":"47","author":[{"given":"Morgan","family":"Humphrey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Everhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desiree","family":"Kosmisky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrtlng.2018.05.008_bib0010","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1097\/CCM.0b013e3181f85759","article-title":"Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients","volume":"38","author":"Shehabi","year":"2010","journal-title":"Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0015","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1097\/ALN.0b013e3181b6a783","article-title":"Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine Compared to Morphine-DEXCOM Study)","volume":"111","author":"Shehabi","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0020","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1164\/rccm.201203-0522OC","article-title":"Early intensive care sedation predicts long-term mortality in ventilated critically ill patients","volume":"186","author":"Shehabi","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0025","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1056\/NEJMra1208705","article-title":"Sedation and delirium in the intensive care unit","volume":"370","author":"Reade","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0030","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1001\/jama.2012.304","article-title":"Dexmedetomidine vs. midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials","volume":"307","author":"Jakob","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0035","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.2165\/11636220-000000000-00000","article-title":"Sedation for critically Ill or injured adults in the intensive care unit: a shifting paradigm","volume":"72","author":"Roberts","year":"2012","journal-title":"Drugs"},{"issue":"3","key":"10.1016\/j.hrtlng.2018.05.008_bib0040","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD005063.pub2","article-title":"Benzodiazepines for alcohol withdrawal","author":"Ntais","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0045","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1177\/1060028015582050","article-title":"Pharmacist leadership in ICU quality improvement: coordination spontaneous awakening and breathing trials","volume":"49","author":"Stollings","year":"2015","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0050","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0140-6736(08)60105-1","article-title":"Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomized controlled trial","volume":"371","author":"Girard","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0055","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1097\/CCM.0000000000000129","article-title":"Effectiveness and safety of the Awakening and Breathing Coordination, Delirium Monitoring\/Management, and Early Exercise\/Mobility (ABCDE) Bundle","volume":"42","author":"Balas","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0060","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/CCM.0b013e3182783b72","article-title":"Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit","volume":"3","author":"Barr","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0065","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.iccn.2005.04.004","article-title":"Use of behavioral pain scale to assess pain in ventilated, unconscious and\/or sedated patients","volume":"22","author":"Young","year":"2006","journal-title":"Intensive Crit Care Nurs"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0070","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/AJP.0b013e31806a23fb","article-title":"Pain assessment in the critically ill ventilated adult: validation of the Critical-Care Pain Observation Tool and physiological indicators","volume":"23","author":"Gelinas","year":"2007","journal-title":"Clin J Pain"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0075","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1001\/jama.289.22.2983","article-title":"Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS)","volume":"289","author":"Ely","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0080","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1097\/00003246-199907000-00022","article-title":"Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients","volume":"27","author":"Riker","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0085","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1097\/00003246-200107000-00012","article-title":"Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)","volume":"29","author":"Ely","year":"2001","journal-title":"Crit Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0090","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00134-007-0920-8","article-title":"Comparison of the confusion assessment method for the intensive care unit (CAM-ICU) with the Intensive Care Delirium Screening Checklist (ICDSC) for delirium in critical care patients gives high agreement rate(s)","volume":"34","author":"Plaschke","year":"2008","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0095","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis","volume":"12","author":"Peduzzi","year":"1996","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.hrtlng.2018.05.008_bib0100","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap) \u2013 A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"}],"container-title":["Heart &amp; Lung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956317303941?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956317303941?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T05:57:11Z","timestamp":1530165431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147956317303941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["S0147956317303941"],"URL":"https:\/\/doi.org\/10.1016\/j.hrtlng.2018.05.008","relation":{},"ISSN":["0147-9563"],"issn-type":[{"value":"0147-9563","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An evaluation of patient-specific characteristics on attainment of target sedation in an intensive care unit","name":"articletitle","label":"Article Title"},{"value":"Heart & Lung","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrtlng.2018.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}