{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:04:18Z","timestamp":1759017858930,"version":"3.44.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartandlung.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart & Lung"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.hrtlng.2022.09.009","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T04:19:15Z","timestamp":1663820355000},"page":"140-143","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["A case report of an 18-year-old receiving nebulized lidocaine for treatment of COVID-19 cough"],"prefix":"10.1016","volume":"57","author":[{"given":"Kelli J","family":"Welter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Snyder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blake","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrtlng.2022.09.009_bib0001","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/S0140-6736(12)60776-4","article-title":"Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial","volume":"380","author":"Ryan","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0002","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/thorax.58.4.339","article-title":"Development of a symptom specific health status measure for patients with chronic cough: leicester cough questionnaire","volume":"58","author":"Birring","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0003","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1378\/chest.15-1271","article-title":"Pregabalin and speech pathology combination therapy for refractory chronic cough: a randomized controlled trial","volume":"149","author":"Vertigan","year":"2016","journal-title":"Chest"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0004","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0954-6111(06)80010-7","article-title":"Chronic persistent cough: use of ipratropium bromide in undiagnosed cases following upper respiratory tract infection","volume":"86","author":"Holmes","year":"1992","journal-title":"Respir Med"},{"issue":"186","key":"10.1016\/j.hrtlng.2022.09.009_bib0005","article-title":"Dosimetrically administered nebulized morphine for breathlessness in very severe COPD","volume":"17","author":"Janowiak","year":"2017","journal-title":"BMC Pulmonary Med"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0006","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1542\/peds.110.3.e38","article-title":"Nebulized morphine as a treatment for dyspnea in a child with cystic fibrosis","volume":"110","author":"Cohen","year":"2002","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.hrtlng.2022.09.009_bib0007","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.chest.2019.11.048","article-title":"Aprepitant for cough suppression in advanced lung cancer","volume":"157","author":"Noronha","year":"2020","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.hrtlng.2022.09.009_bib0008","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1164\/rccm.202006-2359OC","article-title":"Aprepitant for cough in lung cancer. a randomized placebo controlled trial and mechanistic insights","volume":"203","author":"Smith","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.hrtlng.2022.09.009_bib0009","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1378\/chest.105.5.1592","article-title":"Nebulized lidocaine in the treatment of refractory cough","volume":"105","author":"Trochtenberg","year":"1994","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0010","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1053\/ajem.2001.21724","article-title":"Lidocaine inhalation for cough suppression","volume":"19","author":"Udezue","year":"2001","journal-title":"Am J Emergency Med"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0011","first-page":"275","article-title":"Practice tips: treating persistent cough","volume":"4 8","author":"Peleg","year":"2002","journal-title":"Can Fam Physician"},{"issue":"7","key":"10.1016\/j.hrtlng.2022.09.009_bib0012","first-page":"301","article-title":"Nebulized lidocaine for intractable cough near the end of life","volume":"5","author":"Lingerfelt","year":"2007","journal-title":"J Support Oncol"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0013","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1097\/00006534-199311000-00014","article-title":"Tumescent technique for local anesthesia improves safety in large-volume liposuction","volume":"92","author":"Klein","year":"1993","journal-title":"Plastic Reconstr Surg"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0014","first-page":"154","article-title":"Calcium signalling in T cells","volume":"19","author":"Treback","year":"2019","journal-title":"Nat Rev: Immunol"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0015","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0304-3959(99)00268-7","article-title":"Low dose lidocaine reduces secondary hyperalgesia by a central mode of action","volume":"85","author":"Koppert","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0016","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0304-3959(00)00229-3","article-title":"Systemic lidocaine for neuropathic pain relief","volume":"87","author":"Mao","year":"2000","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0017","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1067\/mai.2002.122155","article-title":"Inhibitory effect of lidocaine on T cells from patients with allergic asthma","volume":"109","author":"Tanaka","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0018","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0076-6879(99)14104-1","article-title":"Blockade of neuro- pathic pain by antisense targeting of tetrodotoxin-resistant sodium channels in sensory neurons","volume":"314","author":"Lai","year":"2000","journal-title":"Methods Enzymol"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0019","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1399-6576.2006.00936.x","article-title":"Anti-inflammatory properties of local anesthetics and their present and potential clinical implications","volume":"50","author":"Cassuto","year":"2006","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0020","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jclinane.2016.07.021","article-title":"Effect of endovenous lidocaine on analgesia and serum cytokines: double-blinded and randomized trial","volume":"35","author":"Ortiz","year":"2016","journal-title":"J Clin Anesth"},{"issue":"4","key":"10.1016\/j.hrtlng.2022.09.009_bib0021","doi-asserted-by":"crossref","first-page":"e391","DOI":"10.1016\/j.bja.2020.07.015","article-title":"A novel role for lidocaine in COVID-19 patients?","volume":"125","author":"Finnerty","year":"2020","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0022","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/BOR.0b013e3283546703","article-title":"Lupus neutrophils: \u2018NET'gain in understanding lupus pathogenesis","volume":"24","author":"Knight","year":"2012","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-29026-0","article-title":"Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis","volume":"8","author":"Vajen","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0024","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/MOH.0000000000000303","article-title":"Consequences of extracellular trap formation in sepsis","volume":"24","author":"O'Brien","year":"2017","journal-title":"Curr Opin Hematol"},{"issue":"6","key":"10.1016\/j.hrtlng.2022.09.009_bib0025","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1378\/chest.112.6.1665","article-title":"Nebulized lidocaine administered to infants and children undergoing flexible bronchoscopy","volume":"112","author":"Gjonaj","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2020.109947","article-title":"Nebulized lidocaine in COVID-19, a hypothesis","volume":"144","author":"Ali","year":"2020","journal-title":"Medical Hypotheses"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0027","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.hrtlng.2020.09.001","article-title":"Anti-inflammatory aspects of Lidocaine: a neglected therapeutic stance for COVID-19","author":"Maab","year":"2020","journal-title":"Heart & Lung"},{"issue":"1","key":"10.1016\/j.hrtlng.2022.09.009_bib0028","doi-asserted-by":"crossref","first-page":"59","DOI":"10.35975\/apic.v24i1.1227","article-title":"Lignocaine's substantial role in COVID-19 management: Potential remedial and therapeutic implications","volume":"24","author":"Malik","year":"2020","journal-title":"Anaesth, Pain & Intens Care"},{"issue":"2","key":"10.1016\/j.hrtlng.2022.09.009_bib0029","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1164\/ajrccm\/136.2.447","article-title":"Physiologic effects and serum lidocaine concentrations after inhalation of lidocaine from a compressed gas-powered jet nebulizer","volume":"136","author":"Kirkpatrick","year":"1987","journal-title":"Am Rev Respir Dis"},{"issue":"9","key":"10.1016\/j.hrtlng.2022.09.009_bib0030","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/j.1552-4604.1990.tb01875.x","article-title":"Reduced systemic absorption of intrabronchial lidocaine by high-frequency nebulization","volume":"30","author":"Labedzki","year":"1990","journal-title":"J Clin Pharmacol"},{"key":"10.1016\/j.hrtlng.2022.09.009_bib0031","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1136\/thx.37.1.68","article-title":"Plasma concentrations of lignocaine during fibreopticbronchoscopy","volume":"37","author":"Efthimiou","year":"1982","journal-title":"Thorax"},{"issue":"3","key":"10.1016\/j.hrtlng.2022.09.009_bib0032","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1378\/chest.71.3.346","article-title":"Plasma levels of lidocaine following nebulized aerosol administration","volume":"71","author":"Chinn","year":"1977","journal-title":"Chest"}],"container-title":["Heart & Lung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956322002175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956322002175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T06:40:30Z","timestamp":1758955230000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147956322002175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":32,"alternative-id":["S0147956322002175"],"URL":"https:\/\/doi.org\/10.1016\/j.hrtlng.2022.09.009","relation":{},"ISSN":["0147-9563"],"issn-type":[{"type":"print","value":"0147-9563"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A case report of an 18-year-old receiving nebulized lidocaine for treatment of COVID-19 cough","name":"articletitle","label":"Article Title"},{"value":"Heart & Lung","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrtlng.2022.09.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}