{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T09:53:49Z","timestamp":1773309229578,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartandlung.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart & Lung"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.hrtlng.2025.10.005","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T17:09:05Z","timestamp":1761239345000},"page":"239-246","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Multiparametric integration of cardiac markers in differentiating myocardial infarction with non-obstructive coronary arteries: LASSO regression"],"prefix":"10.1016","volume":"75","author":[{"given":"Qing","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peixuan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwei","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"25","key":"10.1016\/j.hrtlng.2025.10.005_bib0001","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global Burden of cardiovascular diseases and Risk Factors, 1990\u20132019","volume":"76","author":"Roth","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.hrtlng.2025.10.005_bib0002","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1159\/000509100","article-title":"Myocardial infarction with nonobstructive coronary arteries (MINOCA): a review of the current position","volume":"145","author":"Abdu","year":"2020","journal-title":"Cardiology"},{"issue":"18","key":"10.1016\/j.hrtlng.2025.10.005_bib0003","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000000670","article-title":"Contemporary diagnosis and management of patients with myocardial infarction in the absence of obstructive coronary artery disease: a scientific statement from the American Heart Association","volume":"139","author":"Tamis-Holland","year":"2019","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.hrtlng.2025.10.005_bib0004","first-page":"143","article-title":"ESC working group position paper on myocardial infarction with non-obstructive coronary arteries","volume":"38","author":"Agewall","year":"2017","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.hrtlng.2025.10.005_bib0005","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1080\/07853890.2023.2186479","article-title":"Prognostic implications of stress hyperglycemia ratio in patients with myocardial infarction with nonobstructive coronary arteries","volume":"55","author":"Gao","year":"2023","journal-title":"Ann Med"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0006","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ejim.2023.08.011","article-title":"Predictive value of Killip classification in MINOCA patients","volume":"117","author":"Armillotta","year":"2023","journal-title":"Eur J Intern Med"},{"issue":"8","key":"10.1016\/j.hrtlng.2025.10.005_bib0007","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.122.014454","article-title":"Prognostic value of Cardiac Magnetic resonance imaging in patients with a working diagnosis of MINOCA\u2014An outcome study with up to 10 years of follow-up","volume":"16","author":"Konst","year":"2023","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0008","article-title":"The association between fibrinogen-to-albumin ratio and adverse prognosis in patients with myocardial infarction with non-obstructive coronary arteries","volume":"418","author":"Fang","year":"2024","journal-title":"Int J Cardiol"},{"issue":"15","key":"10.1016\/j.hrtlng.2025.10.005_bib0009","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.035000","article-title":"Prognostic implications of resistive reserve ratio in patients with nonobstructive coronary artery disease with myocardial bridging","volume":"13","author":"Mahmoudi Hamidabad","year":"2024","journal-title":"JAHA"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0010","doi-asserted-by":"crossref","first-page":"m441","DOI":"10.1136\/bmj.m441","article-title":"Calculating the sample size required for developing a clinical prediction model","author":"Riley","year":"2020","journal-title":"BMJ"},{"issue":"18","key":"10.1016\/j.hrtlng.2025.10.005_bib0011","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1016\/j.jacc.2018.08.1038","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"72","author":"Thygesen","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0012","doi-asserted-by":"crossref","unstructured":"Papanikolopoulou A., Michalopoulou H., Kyriakoulis K.G., et al. Cardiovascular toxicity associated with Immune checkpoint inhibitors: interpreting the discrepancy between clinical trials and real-world data. Cureus Published online June 30, 2025. doi:10.7759\/cureus.87049.","DOI":"10.7759\/cureus.87049"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1604989","article-title":"The impact of immune checkpoint inhibition on atherosclerosis in cancer patients","volume":"16","author":"Han","year":"2025","journal-title":"Front Immunol"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.117050","article-title":"The mechanisms underlying acute myocardial infarction in chronic kidney disease patients undergoing hemodialysis","volume":"177","author":"Zhu","year":"2024","journal-title":"Biomed Pharmacother"},{"issue":"Supplement_1","key":"10.1016\/j.hrtlng.2025.10.005_bib0015","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.2337\/dc18-S002","article-title":"Classification and diagnosis of diabetes: standards of medical care in diabetes\u20142018","volume":"41","year":"2018","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.hrtlng.2025.10.005_bib0016","doi-asserted-by":"crossref","first-page":"558","DOI":"10.4097\/kja.19087","article-title":"Multicollinearity and misleading statistical results","volume":"72","author":"Kim","year":"2019","journal-title":"Korean J Anesth"},{"issue":"1","key":"10.1016\/j.hrtlng.2025.10.005_bib0017","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12933-021-01384-6","article-title":"Impact of admission hyperglycemia on short and long-term prognosis in acute myocardial infarction: MINOCA versus MIOCA","volume":"20","author":"Paolisso","year":"2021","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0018","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.trsl.2020.11.009","article-title":"Revisiting the use of the provocative acetylcholine test in patients with chest pain and nonobstructive coronary arteries: a five-year follow-up of the AChPOL registry, with special focus on patients with MINOCA","volume":"231","author":"Bil","year":"2021","journal-title":"Transl Res"},{"issue":"20","key":"10.1016\/j.hrtlng.2025.10.005_bib0019","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/j.jcin.2022.08.023","article-title":"Differences in demographics and outcomes between men and women with spontaneous coronary artery dissection","volume":"15","author":"McAlister","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0020","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ijcard.2022.11.032","article-title":"Sex differences in patients with acute coronary syndromes and non-obstructive coronary arteries: presentation and outcome","volume":"372","author":"Williams","year":"2023","journal-title":"Int J Cardiol"},{"issue":"15","key":"10.1016\/j.hrtlng.2025.10.005_bib0021","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.035329","article-title":"Sex differences and clinical outcomes in patients with myocardial infarction with nonobstructive coronary arteries: a meta-analysis","volume":"13","author":"Ang","year":"2024","journal-title":"JAHA"},{"issue":"7","key":"10.1016\/j.hrtlng.2025.10.005_bib0022","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/MCA.0000000000001018","article-title":"Myocardial infarct size and sex-related angiographic differences in myocardial infarction in nonobstructive coronary artery disease","volume":"32","author":"Alkhawam","year":"2021","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.hrtlng.2025.10.005_bib0023","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ahj.2018.03.005","article-title":"Prognosis in relation to high-sensitivity cardiac troponin T levels in patients with myocardial infarction and non-obstructive coronary arteries","volume":"200","author":"Hjort","year":"2018","journal-title":"Am Heart J"},{"issue":"1","key":"10.1016\/j.hrtlng.2025.10.005_bib0024","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.027466","article-title":"Biomarker concentrations and their temporal changes in patients with myocardial infarction and nonobstructive compared with obstructive coronary arteries: results from the PLATO trial","volume":"12","author":"Hjort","year":"2023","journal-title":"JAHA"},{"issue":"6","key":"10.1016\/j.hrtlng.2025.10.005_bib0025","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/FJC.0000000000000918","article-title":"Effect of secondary prevention medication on the prognosis in patients with myocardial infarction with nonobstructive coronary artery disease","volume":"76","author":"Abdu","year":"2020","journal-title":"J Cardiovasc Pharmacol"},{"issue":"11","key":"10.1016\/j.hrtlng.2025.10.005_bib0026","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCOUTCOMES.121.007880","article-title":"Survival in patients with suspected myocardial infarction with nonobstructive coronary arteries: a comprehensive systematic review and meta-analysis from the MINOCA Global Collaboration","volume":"14","author":"Pasupathy","year":"2021","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"11","key":"10.1016\/j.hrtlng.2025.10.005_bib0027","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.43402","article-title":"Mortality in ST-segment elevation myocardial infarction with nonobstructive coronary arteries and mimickers","volume":"6","author":"Quesada","year":"2023","journal-title":"JAMA Netw Open"}],"container-title":["Heart & Lung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956325002195?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0147956325002195?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T15:42:07Z","timestamp":1773243727000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0147956325002195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":27,"alternative-id":["S0147956325002195"],"URL":"https:\/\/doi.org\/10.1016\/j.hrtlng.2025.10.005","relation":{},"ISSN":["0147-9563"],"issn-type":[{"value":"0147-9563","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiparametric integration of cardiac markers in differentiating myocardial infarction with non-obstructive coronary arteries: LASSO regression","name":"articletitle","label":"Article Title"},{"value":"Heart & Lung","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrtlng.2025.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}