{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:09:27Z","timestamp":1777784967061,"version":"3.51.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"vor","delay-in-days":34,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004909","name":"Universidade Federal do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004909","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hematology, Transfusion and Cell Therapy"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.htct.2025.103744","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T20:02:48Z","timestamp":1740600168000},"page":"103744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of blueberry extract on hematological response in phenylhydrazine-induced hemolytic anemia"],"prefix":"10.1016","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7677-1221","authenticated-orcid":false,"given":"Daniela","family":"Drosdowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5994-5218","authenticated-orcid":false,"given":"Patrick","family":"T\u00fcrck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7184-1072","authenticated-orcid":false,"given":"Silvio","family":"Tasca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0277-7855","authenticated-orcid":false,"given":"Gabriel de Lima","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8155-7561","authenticated-orcid":false,"given":"Edson Fernando Muller","family":"Guzzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3759-6587","authenticated-orcid":false,"given":"Sara Elis","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3599-8627","authenticated-orcid":false,"given":"Adriana Simon","family":"Coitinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3428-4369","authenticated-orcid":false,"given":"Cristina Campos","family":"Carraro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8340-7759","authenticated-orcid":false,"given":"Adriane","family":"Bell\u00f3-Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4212-8374","authenticated-orcid":false,"given":"Alexandre Luz","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9525-5855","authenticated-orcid":false,"given":"Valquiria Linck","family":"Bassani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9482-7388","authenticated-orcid":false,"given":"Alex Sander da Rosa","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.htct.2025.103744_bib0001","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/nyas.15062","article-title":"Review of intervention products for use in the prevention and control of anemia","volume":"1529","author":"Lopez De Roma\u00f1a","year":"2023","journal-title":"Ann N Y Acad Sci"},{"issue":"7","key":"10.1016\/j.htct.2025.103744_bib0002","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/ggi.14183","article-title":"Anemia in older adults as a geriatric syndrome: a review","volume":"21","author":"Katsumi","year":"2021","journal-title":"Geriatr Gerontol Int"},{"issue":"4","key":"10.1016\/j.htct.2025.103744_bib0003","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.revmed.2018.10.387","article-title":"Maladies h\u00e9molytiques et thrombose veineuse: mise au point [Hemolytic disorders and venous thrombosis: an update]","volume":"40","author":"Lecouffe-Desprets","year":"2019","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.htct.2025.103744_bib0004","doi-asserted-by":"crossref","first-page":"e16576","DOI":"10.7717\/peerj.16576","article-title":"Hematopoietic effect of echinochrome on phenylhydrazine-induced hemolytic anemia in rats","volume":"11","author":"EL-Shehry","year":"2023","journal-title":"Peer J"},{"issue":"7","key":"10.1016\/j.htct.2025.103744_bib0005","doi-asserted-by":"crossref","first-page":"609","DOI":"10.2174\/156652408786241384","article-title":"The role of oxidative stress in hemolytic anemia","volume":"8","author":"Fibach","year":"2008","journal-title":"Curr Mol Med"},{"issue":"5","key":"10.1016\/j.htct.2025.103744_bib0006","first-page":"562","article-title":"Erythrocytes as a preferential target of oxidative stress in blood","volume":"55","author":"Fujii","year":"2021","journal-title":"Free Radic Res"},{"issue":"2","key":"10.1016\/j.htct.2025.103744_bib0007","first-page":"239","article-title":"Anti-anemic effect of antioxidant-rich apple vinegar against phenylhydrazine-induced hemolytic anemia in rats","volume":"12","author":"Ousaaid","year":"2022","journal-title":"Life (Basel)"},{"issue":"1","key":"10.1016\/j.htct.2025.103744_bib0008","doi-asserted-by":"crossref","first-page":"11976","DOI":"10.1038\/s41598-023-39269-1","article-title":"Blueberry intake elevates post-exercise anti-inflammatory oxylipins: a randomized trial","volume":"13","author":"Nieman","year":"2023","journal-title":"Sci Rep"},{"issue":"8","key":"10.1016\/j.htct.2025.103744_bib0009","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.sdentj.2023.07.021","article-title":"Antitumoral properties of pomegranate peel and blueberry extracts against tongue carcinoma (in vitro study)","volume":"35","author":"Ahmed","year":"2023","journal-title":"Saudi Dent J"},{"issue":"2","key":"10.1016\/j.htct.2025.103744_bib0010","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1002\/jsfa.12964","article-title":"Phytochemical profiles, antioxidant activities, and synergistic antiproliferative effects of blueberry and apple peel extracts","volume":"104","author":"Xia","year":"2024","journal-title":"J Sci Food Agric"},{"issue":"3","key":"10.1016\/j.htct.2025.103744_bib0011","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s11010-021-04313-z","article-title":"Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells","volume":"477","author":"T\u00fcrck","year":"2022","journal-title":"Mol Cell Biochem"},{"issue":"6","key":"10.1016\/j.htct.2025.103744_bib0012","doi-asserted-by":"crossref","first-page":"589","DOI":"10.3390\/membranes13060589","article-title":"Analysis of the polyphenolic composition of vaccinium L. Extracts and their protective effect on red blood cell membranes","volume":"13","author":"Ka\u017amierczak","year":"2023","journal-title":"Membranes (Basel)."},{"issue":"1","key":"10.1016\/j.htct.2025.103744_bib0013","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s00394-021-02642-9","article-title":"Blueberry extract improves redox balance and functional parameters in the right ventricle from rats with pulmonary arterial hypertension","volume":"61","author":"T\u00fcrck","year":"2022","journal-title":"Eur J Nutr"},{"issue":"4","key":"10.1016\/j.htct.2025.103744_bib0014","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1172\/JCI101847","article-title":"The osmotic resistance (fragility) of human red cells","volume":"26","author":"Parpart","year":"1947","journal-title":"J Clin Investigat"},{"issue":"1","key":"10.1016\/j.htct.2025.103744_bib0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0034-5288(18)32437-8","article-title":"Haematological studies on normal lactating Indian water buffaloes","volume":"32","author":"Jain","year":"1982","journal-title":"Res Vet Sci"},{"issue":"2","key":"10.1016\/j.htct.2025.103744_bib0016","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/tx00026a012","article-title":"Evaluation of the probe 2\u2032,7\u2032-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress","volume":"5","author":"LeBel","year":"1992","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.htct.2025.103744_bib0017","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0076-6879(81)77038-1","volume":"77","author":"-Mannervik","year":"1981","journal-title":"Methods Enzymol"},{"issue":"1","key":"10.1016\/j.htct.2025.103744_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/tox.20383","article-title":"Comparative effect of melatonin and vitamin E on phenylhydrazine-induced toxicity in the spleen of Funambulus pennanti","volume":"24","author":"Sharma","year":"2009","journal-title":"Environ Toxicol"},{"issue":"9","key":"10.1016\/j.htct.2025.103744_bib0019","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1139\/apnm-2019-0864","article-title":"Pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress","volume":"45","author":"Lacerda","year":"2020","journal-title":"Appl Physiol Nutr Metab"},{"issue":"2","key":"10.1016\/j.htct.2025.103744_bib0020","doi-asserted-by":"crossref","first-page":"435","DOI":"10.36660\/abc.20201155","article-title":"Pterostilbene reduces experimental myocardial infarction-induced oxidative stress in lung and right ventricle","volume":"118","author":"Tasca","year":"2022","journal-title":"Arq Bras Cardiol"},{"issue":"5","key":"10.1016\/j.htct.2025.103744_bib0021","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s12038-018-9815-9","article-title":"Profile of pterostilbene-induced redox homeostasis modulation in cardiac myoblasts and heart tissue","volume":"43","author":"Couto","year":"2018","journal-title":"J Biosci"},{"key":"10.1016\/j.htct.2025.103744_bib0022","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.freeradbiomed.2018.06.037","article-title":"Transferrin and transferrin receptors update","volume":"133","author":"Kawabata","year":"2019","journal-title":"Free Radic Biol Med"},{"issue":"8","key":"10.1016\/j.htct.2025.103744_bib0023","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1161\/ATVBAHA.123.318780","article-title":"Basic mechanisms of hemolysis-associated thrombo-inflammation and immune dysregulation","volume":"43","author":"DImitrov","year":"2023","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.htct.2025.103744_bib0024","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3389\/fimmu.2020.00454","article-title":"The red blood cell-inflammation vicious circle in sickle cell disease","volume":"11","author":"Nader","year":"2020","journal-title":"Front Immunol"},{"issue":"3","key":"10.1016\/j.htct.2025.103744_bib0025","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1172\/JCI89741","article-title":"Intravascular hemolysis and the pathophysiology of sickle cell disease","volume":"127","author":"Kato","year":"2017","journal-title":"J Clin Invest"},{"issue":"3","key":"10.1016\/j.htct.2025.103744_bib0026","first-page":"435","article-title":"Erythrocytes, leukocytes and platelets as a source of oxidative stress in chronic vascular diseases: detoxifying mechanisms and potential therapeutic options","volume":"108","author":"Martin-Ventura","year":"2012","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.htct.2025.103744_bib0027","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1080\/17474086.2017.1327809","article-title":"Heme-mediated cell activation: the inflammatory puzzle of sickle cell anemia","volume":"10","author":"Guarda","year":"2017","journal-title":"Expert Rev Hematol"},{"issue":"4","key":"10.1016\/j.htct.2025.103744_bib0028","doi-asserted-by":"crossref","first-page":"e15370","DOI":"10.1016\/j.heliyon.2023.e15370","article-title":"Blueberry and cranberry extracts mitigate CCL4-induced liver damage, suppressing liver fibrosis, inflammation and oxidative stress","volume":"9","author":"Sergazy","year":"2023","journal-title":"Heliyon"}],"container-title":["Hematology, Transfusion and Cell Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2531137925000124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2531137925000124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T13:03:27Z","timestamp":1741871007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2531137925000124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S2531137925000124"],"URL":"https:\/\/doi.org\/10.1016\/j.htct.2025.103744","relation":{},"ISSN":["2531-1379"],"issn-type":[{"value":"2531-1379","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of blueberry extract on hematological response in phenylhydrazine-induced hemolytic anemia","name":"articletitle","label":"Article Title"},{"value":"Hematology, Transfusion and Cell Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.htct.2025.103744","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Associa\u00e7\u00e3o Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"103744"}}