{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:14:43Z","timestamp":1763036083657,"version":"3.32.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.humimm.2005.09.003","type":"journal-article","created":{"date-parts":[[2005,11,5]],"date-time":"2005-11-05T12:38:11Z","timestamp":1131194291000},"page":"125-139","source":"Crossref","is-referenced-by-count":71,"title":["Disease Relevant HLA Class II Alleles Isolated by Genotypic, Haplotypic, and Sequence Analysis in North American Caucasians With Pemphigus Vulgaris"],"prefix":"10.1016","volume":"67","author":[{"given":"Erica","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine A.","family":"Lendas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selwyn","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin","family":"Pirani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Dionisio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Spizuoco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilena","family":"Fotino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Animesh A.","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2005.09.003_bib1","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1038\/ni0901-802","article-title":"The genetics of complex autoimmune diseases","volume":"2","author":"Wandstrat","year":"2001","journal-title":"Nat Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib2","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1126\/science.1972595","article-title":"Autoimmune diseases","volume":"248","author":"Sinha","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.humimm.2005.09.003_bib3","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1126\/science.3368786","article-title":"A molecular basis for MHC class II\u2013associated autoimmunity","volume":"240","author":"Todd","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.humimm.2005.09.003_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1046\/j.1365-2370.2003.00369.x","article-title":"HLA-DPB1*0401 is associated with dominant protection against type 1 diabetes in the general Saudi population and in subjects with a high-risk DR\/DQ haplotype","volume":"30","author":"Al-Hussein","year":"2003","journal-title":"Eur J Immunogenet"},{"key":"10.1016\/j.humimm.2005.09.003_bib5","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1111\/j.1346-8138.1994.tb03298.x","article-title":"Autoantibodies against cell adhesion molecules in pemphigus","volume":"21","author":"Amagai","year":"1994","journal-title":"J Dermatol"},{"key":"10.1016\/j.humimm.2005.09.003_bib6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1399-0039.1994.tb02390.x","article-title":"HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method","volume":"44","author":"Niizeki","year":"1994","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib7","doi-asserted-by":"crossref","first-page":"6542","DOI":"10.1073\/pnas.84.18.6542","article-title":"Detection of disease-specific restriction fragment length polymorphisms in pemphigus vulgaris linked to the DQw1 and DQw3 alleles of the HLA-D region","volume":"84","author":"Szafer","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib8","doi-asserted-by":"crossref","first-page":"7658","DOI":"10.1073\/pnas.87.19.7658","article-title":"Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris","volume":"87","author":"Ahmed","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib9","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1126\/science.2894075","article-title":"A newly characterized HLA DQ beta allele associated with pemphigus vulgaris","volume":"239","author":"Sinha","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.humimm.2005.09.003_bib10","doi-asserted-by":"crossref","first-page":"6215","DOI":"10.1073\/pnas.86.16.6215","article-title":"Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris","volume":"86","author":"Scharf","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib11","doi-asserted-by":"crossref","first-page":"3504","DOI":"10.1073\/pnas.85.10.3504","article-title":"HLA class II allelic variation and susceptibility to pemphigus vulgaris","volume":"85","author":"Scharf","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/jaut.2000.0388","article-title":"HLA class II polymorphism contributes to specify desmoglein derived peptides in pemphigus vulgaris and pemphigus foliaceus","volume":"15","author":"Loiseau","year":"2000","journal-title":"J Autoimmun"},{"key":"10.1016\/j.humimm.2005.09.003_bib13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1399-0039.1996.tb02545.x","article-title":"Molecular analysis of HLA DRB1 and DQB1 in Italian patients with pemphigus vulgaris","volume":"47","author":"Lombardi","year":"1996","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib14","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1399-0039.1998.tb03043.x","article-title":"Distribution of HLA class II alleles among Spanish patients with pemphigus vulgaris","volume":"52","author":"Gonzalez-Escribano","year":"1998","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib15","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s10227-001-0157-z","article-title":"HLA haplotypes and class II molecular alleles in Argentinian patients with pemphigus vulgaris","volume":"6","author":"Glorio","year":"2002","journal-title":"J Cutan Med Surg"},{"key":"10.1016\/j.humimm.2005.09.003_bib16","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0198-8859(97)00182-1","article-title":"Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris","volume":"57","author":"Mobini","year":"1997","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib17","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1399-0039.1998.tb03026.x","article-title":"Polymorphisms of HLA class II genes in Japanese patients with pemphigus vulgaris","volume":"52","author":"Yamashina","year":"1998","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib18","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0198-8859(97)00203-6","article-title":"Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients","volume":"57","author":"Delgado","year":"1997","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib19","first-page":"79","article-title":"[Association between HLA-DRB1, DQB1 genes and pemphigus vulgaris in Chinese Hans]","volume":"20","author":"Zhou","year":"2003","journal-title":"Zhonghua Yi Xue Yi Chuan Xue Za Zhi"},{"key":"10.1016\/j.humimm.2005.09.003_bib20","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/1523-1747.ep12337585","article-title":"HLA-DRB1*04 and DRB1*14 alleles are associated with susceptibility to pemphigus among Japanese","volume":"109","author":"Miyagawa","year":"1997","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humimm.2005.09.003_bib21","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1111\/j.1399-0039.1996.tb02690.x","article-title":"MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India","volume":"48","author":"Delgado","year":"1996","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib22","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1399-0039.1996.tb02689.x","article-title":"HLA haplotypes and class II molecular alleles in Sardinian and Italian patients with pemphigus vulgaris","volume":"48","author":"Carcassi","year":"1996","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1523-1747.1999.00626.x","article-title":"Common human leukocyte antigen alleles in pemphigus vulgaris and pemphigus foliaceus Italian patients","volume":"113","author":"Lombardi","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humimm.2005.09.003_bib24","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1034\/j.1399-0039.2003.00103.x","article-title":"New HLA haplotype frequency reference standards","volume":"62","author":"Klitz","year":"2003","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib25","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1399-0039.1995.tb02485.x","article-title":"Comparative analysis of HLA polymorphism at the serologic and molecular level in Moroccan and Ashkenazi Jews","volume":"46","author":"Roitberg-Tambur","year":"1995","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib26","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1399-0039.1992.tb01940.x","article-title":"HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours","volume":"39","author":"Olerup","year":"1992","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib27","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1365-2230.2004.01528.x","article-title":"Haplotype associations of the MHC with psoriasis vulgaris in Chinese Hans","volume":"29","author":"Yang","year":"2004","journal-title":"Clin Exp Dermatol"},{"year":"2005","series-title":"Binomial. SISA","author":"Uitenbrock","key":"10.1016\/j.humimm.2005.09.003_bib28"},{"year":"2005","series-title":"FINETTI","author":"Strom","key":"10.1016\/j.humimm.2005.09.003_bib29"},{"key":"10.1016\/j.humimm.2005.09.003_bib30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate","volume":"57","author":"Benjamini","year":"1995","journal-title":"J Roy Statist Soc B"},{"key":"10.1016\/j.humimm.2005.09.003_bib31","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0166-4328(01)00297-2","article-title":"Controlling the false discovery rate in behavior genetics research","volume":"125","author":"Benjamini","year":"2001","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.humimm.2005.09.003_bib32","first-page":"1107","article-title":"Testing linkage disequilibrium between a disease gene and marker loci","volume":"53","author":"Xie","year":"1993","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2005.09.003_bib33","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1006\/geno.2000.6190","article-title":"Significant evidence for linkage disequilibrium over a 5-cM region among Afrikaners","volume":"66","author":"Gordon","year":"2000","journal-title":"Genomics"},{"key":"10.1016\/j.humimm.2005.09.003_bib34","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1093\/bioinformatics\/bth071","article-title":"Gene counting and HAP","volume":"20","author":"Zhao","year":"2004","journal-title":"Bioinformatics"},{"key":"10.1016\/j.humimm.2005.09.003_bib35","first-page":"28","article-title":"[PCR determination of an association between class II HLA and pemphigus vulgaris]","volume":"59","author":"Glorio","year":"1999","journal-title":"Medicina (B Aires)"},{"key":"10.1016\/j.humimm.2005.09.003_bib36","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1034\/j.1399-0039.1999.540402.x","article-title":"HLA-DRB1 polymorphisms and autoimmune responses to desmogleins in Japanese patients with pemphigus","volume":"54","author":"Miyagawa","year":"1999","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib37","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.2307\/2533494","article-title":"From genotypes to genes","volume":"53","author":"Sasieni","year":"1997","journal-title":"Biometrics"},{"key":"10.1016\/j.humimm.2005.09.003_bib38","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3109\/08916939908993852","article-title":"HLA class II restriction of autoreactive T cell responses in pemphigus vulgaris","volume":"30","author":"Riechers","year":"1999","journal-title":"Autoimmunity"},{"key":"10.1016\/j.humimm.2005.09.003_bib39","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1046\/j.1523-1747.1998.00156.x","article-title":"Heterogeneous MHC II restriction pattern of autoreactive desmoglein 3 specific T cell responses in pemphigus vulgaris patients and normals","volume":"110","author":"Hertl","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humimm.2005.09.003_bib40","doi-asserted-by":"crossref","first-page":"11935","DOI":"10.1073\/pnas.92.25.11935","article-title":"Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity","volume":"92","author":"Wucherpfennig","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib41","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1034\/j.1399-0039.2000.550313.x","article-title":"Novel associations among HLA-DQA1 and -DQB1 alleles, revealed by high-resolution sequence-based typing (SBT)","volume":"55","author":"Pera","year":"2000","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2005.09.003_bib42","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/sj.gene.6363875","article-title":"Genetics of type 1 diabetes mellitus","volume":"3","author":"Pociot","year":"2002","journal-title":"Genes Immun"},{"key":"10.1016\/j.humimm.2005.09.003_bib43","doi-asserted-by":"crossref","first-page":"8111","DOI":"10.1073\/pnas.85.21.8111","article-title":"Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes","volume":"85","author":"Morel","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib44","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1093\/intimm\/10.8.1229","article-title":"The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules","volume":"10","author":"Quarsten","year":"1998","journal-title":"Int Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib45","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/S0165-5728(01)00456-8","article-title":"HLA class II associated risk and protection against multiple sclerosis-a Finnish family study","volume":"122","author":"Laaksonen","year":"2002","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib46","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0198-8859(03)00017-X","article-title":"HLA class II antigens associated with lupus nephritis in Italian SLE patients","volume":"64","author":"Marchini","year":"2003","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib47","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0198-8859(01)00226-9","article-title":"Protection against severe disease is conferred by DERAA-bearing HLA-DRB1 alleles among HLA-DQ3 and HLA-DQ5 positive rheumatoid arthritis patients","volume":"62","author":"Seidl","year":"2001","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib48","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0198-8859(98)00101-3","article-title":"HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis","volume":"60","author":"van der Horst-Bruinsma","year":"1999","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib49","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.humimm.2003.12.009","article-title":"HLA-DRB1 alleles encoding the \u201cshared epitope\u201d are associated with susceptibility to developing rheumatoid arthritis whereas HLA-DRB1 alleles encoding an aspartic acid at position 70 of the beta-chain are protective in Mexican Mestizos","volume":"65","author":"Ruiz-Morales","year":"2004","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib50","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1136\/ard.2004.023333","article-title":"Evidence for negative association of the chemokine receptor CCR5 d32 polymorphism with rheumatoid arthritis","volume":"64","author":"Pokorny","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.humimm.2005.09.003_bib51","first-page":"232","article-title":"HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis","volume":"28","author":"Mattey","year":"2001","journal-title":"J Rheumatol"},{"key":"10.1016\/j.humimm.2005.09.003_bib52","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/0167-5699(95)80181-2","article-title":"Could HLA-DRB1 be the protective locus in rheumatoid arthritis?","volume":"16","author":"Zanelli","year":"1995","journal-title":"Immunol Today"},{"key":"10.1016\/j.humimm.2005.09.003_bib53","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1084\/jem.177.2.419","article-title":"Linkage of pemphigus vulgaris antibody to the major histocompatibility complex in healthy relatives of patients","volume":"177","author":"Ahmed","year":"1993","journal-title":"J Exp Med"},{"key":"10.1016\/j.humimm.2005.09.003_bib54","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0198-8859(99)00146-9","article-title":"HLA-DQ6-mediated protection in IDDM","volume":"61","author":"SanJeevi","year":"2000","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2005.09.003_bib55","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1073\/pnas.88.11.5056","article-title":"Major histocompatibility complex haplotypes and class II genes in non-Jewish patients with pemphigus vulgaris","volume":"88","author":"Ahmed","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humimm.2005.09.003_bib56","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3109\/08916930008994081","article-title":"Correlation between profile of circulating mononuclear cells and clinical manifestations in patients with pemphigus vulgaris","volume":"32","author":"Gonzalez","year":"2000","journal-title":"Autoimmunity"},{"key":"10.1016\/j.humimm.2005.09.003_bib57","first-page":"95","article-title":"An investigation of the effect of misclassification on the properties of chi-2-tests in the analysis of categorical data","volume":"52","author":"Mote","year":"1965","journal-title":"Biometrika"},{"key":"10.1016\/j.humimm.2005.09.003_bib58","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000066696","article-title":"Power and sample size calculations for case-control genetic association tests when errors are present","volume":"54","author":"Gordon","year":"2002","journal-title":"Hum Hered"},{"year":"2000","series-title":"The HLA FactsBook","author":"Marsh","key":"10.1016\/j.humimm.2005.09.003_bib59"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885905004234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885905004234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T10:17:32Z","timestamp":1736072252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885905004234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":59,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0198885905004234"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2005.09.003","relation":{},"ISSN":["0198-8859"],"issn-type":[{"type":"print","value":"0198-8859"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}