{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T07:35:58Z","timestamp":1762673758727},"reference-count":39,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.humimm.2010.02.009","type":"journal-article","created":{"date-parts":[[2010,3,9]],"date-time":"2010-03-09T09:59:58Z","timestamp":1268128798000},"page":"520-524","source":"Crossref","is-referenced-by-count":15,"title":["A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients"],"prefix":"10.1016","volume":"71","author":[{"given":"Satoru","family":"Joshita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeji","family":"Umemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaname","family":"Yoshizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiko","family":"Katsuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiji","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Ota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2010.02.009_bib1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1002\/hep.22042","article-title":"The causes of primary biliary cirrhosis: Convenient and inconvenient truths","volume":"47","author":"Gershwin","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib2","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1056\/NEJMra043898","article-title":"Primary biliary cirrhosis","volume":"353","author":"Kaplan","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humimm.2010.02.009_bib3","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1002\/hep.20907","article-title":"Risk factors and comorbidities in primary biliary cirrhosis: A controlled interview-based study of 1032 patients","volume":"42","author":"Gershwin","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/j.1440-1746.2004.03396.x","article-title":"Prevalence of immune disturbances and chronic liver disease in family members of patients with primary biliary cirrhosis","volume":"19","author":"Bittencourt","year":"2004","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.humimm.2010.02.009_bib5","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1053\/j.gastro.2004.05.005","article-title":"Primary biliary cirrhosis in monozygotic and dizygotic twins: Genetics, epigenetics, and environment","volume":"127","author":"Selmi","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.humimm.2010.02.009_bib6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/jaut.1999.0299","article-title":"Familial primary biliary cirrhosis in Hiroshima","volume":"13","author":"Tsuji","year":"1999","journal-title":"J Autoimmun"},{"key":"10.1016\/j.humimm.2010.02.009_bib7","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1056\/NEJMoa0810440","article-title":"Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants","volume":"360","author":"Hirschfield","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humimm.2010.02.009_bib8","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1053\/j.gastro.2008.06.077","article-title":"Primary biliary cirrhosis is associated with a genetic variant in the 3\u2032 flanking region of the CTLA4 gene","volume":"135","author":"Juran","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.humimm.2010.02.009_bib9","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1002\/art.24412","article-title":"CTLA4\/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population","volume":"60","author":"Walker","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.humimm.2010.02.009_bib10","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.jhep.2008.07.027","article-title":"Genetic factors of susceptibility and of severity in primary biliary cirrhosis","volume":"49","author":"Poupon","year":"2008","journal-title":"J Hepatol"},{"key":"10.1016\/j.humimm.2010.02.009_bib11","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/hep.22382","article-title":"Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis","volume":"48","author":"Ohishi","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib12","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/hep.21316","article-title":"HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: A large-scale study","volume":"44","author":"Donaldson","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib13","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1002\/hep.22567","article-title":"Human leukocyte antigen polymorphisms in Italian primary biliary cirrhosis: A multicenter study of 664 patients and 1992 healthy controls","volume":"48","author":"Invernizzi","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhep.2009.01.015","article-title":"Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations","author":"Tanaka","year":"2009","journal-title":"J Hepatol"},{"key":"10.1016\/j.humimm.2010.02.009_bib15","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/hep.22906","article-title":"Primary biliary cirrhosis","volume":"50","author":"Lindor","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib16","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF00432479","article-title":"Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)","volume":"379","author":"Ludwig","year":"1978","journal-title":"Virchows Arch A Pathol Anat Histol"},{"key":"10.1016\/j.humimm.2010.02.009_bib17","doi-asserted-by":"crossref","first-page":"179","DOI":"10.4065\/73.2.179","article-title":"Pathologic features and evolution of primary biliary cirrhosis and primary sclerosing cholangitis","volume":"73","author":"Scheuer","year":"1998","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.humimm.2010.02.009_bib18","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1053\/jhep.2002.30902","article-title":"Primary biliary cirrhosis with additional features of autoimmune hepatitis: Response to therapy with ursodeoxycholic acid","volume":"35","author":"Joshi","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib19","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1399-0039.1992.tb01935.x","article-title":"HLA-DRB1 genotyping by modified PCR-RFLP method combined with group-specific primers","volume":"39","author":"Ota","year":"1992","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2010.02.009_bib20","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1399-0039.1991.tb01882.x","article-title":"Modified PCR-RFLP method for HLA-DPB1 and \u2212DQA1 genotyping","volume":"38","author":"Ota","year":"1991","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2010.02.009_bib21","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1038\/nprot.2007.407","article-title":"Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism","volume":"2","author":"Ota","year":"2007","journal-title":"Nat Protoc"},{"key":"10.1016\/j.humimm.2010.02.009_bib22","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1002\/hep.21518","article-title":"A genomewide DNA microsatellite association study of Japanese patients with autoimmune hepatitis type 1","volume":"45","author":"Yokosawa","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.humimm.2010.02.009_bib23","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jhep.2004.12.019","article-title":"Genetic analysis of the HLA region of Japanese patients with type 1 autoimmune hepatitis","volume":"42","author":"Yoshizawa","year":"2005","journal-title":"J Hepatol"},{"key":"10.1016\/j.humimm.2010.02.009_bib24","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/oxfordjournals.jhered.a111573","article-title":"GENEPOP (version-1.2)\u2014population-genetics software for exact tests and ecumenicism","volume":"86","author":"Raymond","year":"1995","journal-title":"J Hered"},{"key":"10.1016\/j.humimm.2010.02.009_bib25","first-page":"103","article-title":"GENEPOP. 007: A complete re-implementation of the GENEPOP software for Windows and Linux","volume":"8","author":"Rousset","year":"2008","journal-title":"Resources"},{"key":"10.1016\/j.humimm.2010.02.009_bib26","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1086\/425870","article-title":"Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility loci","volume":"75","author":"Schaid","year":"2004","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib27","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1093\/hmg\/ddi234","article-title":"Whole genome association study of rheumatoid arthritis using 27 039 microsatellites","volume":"14","author":"Tamiya","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib28","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1086\/302364","article-title":"The critical region for Behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping","volume":"64","author":"Ota","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1006\/geno.2000.6371","article-title":"A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region","volume":"71","author":"Ota","year":"2001","journal-title":"Genomics"},{"key":"10.1016\/j.humimm.2010.02.009_bib30","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/hmg\/9.9.1303","article-title":"A novel protein with RNA-binding motifs interacts with ataxin-2","volume":"9","author":"Shibata","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib31","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00335-001-2056-4","article-title":"Identification and expression of a mouse ortholog of A2BP1","volume":"12","author":"Kiehl","year":"2001","journal-title":"Mamm Genome"},{"key":"10.1016\/j.humimm.2010.02.009_bib32","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature07509","article-title":"Alternative isoform regulation in human tissue transcriptomes","volume":"456","author":"Wang","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.humimm.2010.02.009_bib33","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/ajmg.b.30530","article-title":"Cytogenetic and molecular characterization of A2BP1\/FOX1 as a candidate gene for autism","volume":"144B","author":"Martin","year":"2007","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib34","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1001\/archpsyc.65.6.683","article-title":"Molecular genetics of successful smoking cessation: Convergent genome-wide association study results","volume":"65","author":"Uhl","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.humimm.2010.02.009_bib35","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1200\/JCO.2008.18.7906","article-title":"Genome-wide analysis of survival in early-stage non-small-cell lung cancer","volume":"27","author":"Huang","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humimm.2010.02.009_bib36","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1136\/jmg.2009.067314","article-title":"A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: The Treat-OA Consortium","volume":"46","author":"Zhai","year":"2009","journal-title":"J Med Genet"},{"key":"10.1016\/j.humimm.2010.02.009_bib37","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1128\/MCB.01015-06","article-title":"Role for Fox-1\/Fox-2 in mediating the neuronal pathway of calcitonin\/calcitonin gene-related peptide alternative RNA processing","volume":"27","author":"Zhou","year":"2007","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.humimm.2010.02.009_bib38","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1210\/edrv-17-5-533","article-title":"Calcitonin gene-related peptide and its receptors: Molecular genetics, physiology, pathophysiology, and therapeutic potentials","volume":"17","author":"Wimalawansa","year":"1996","journal-title":"Endocr Rev"},{"key":"10.1016\/j.humimm.2010.02.009_bib39","doi-asserted-by":"crossref","first-page":"16702","DOI":"10.1073\/pnas.0705974104","article-title":"Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice","volume":"104","author":"Tsujikawa","year":"2007","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885910000455?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885910000455?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,26]],"date-time":"2019-05-26T19:33:26Z","timestamp":1558899206000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885910000455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0198885910000455"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2010.02.009","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}