{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T16:45:36Z","timestamp":1771001136072,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.humimm.2012.05.004","type":"journal-article","created":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T18:34:34Z","timestamp":1337279674000},"page":"805-810","source":"Crossref","is-referenced-by-count":28,"title":["Pathway analysis of genome-wide association studies on uric acid concentrations"],"prefix":"10.1016","volume":"73","author":[{"given":"Young Ho","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwan Gyu","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2012.05.004_b0005","doi-asserted-by":"crossref","first-page":"R177","DOI":"10.1093\/hmg\/ddp369","article-title":"Recent insights into the pathogenesis of hyperuricaemia and gout","volume":"18","author":"Riches","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0010","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0140-6736(09)60883-7","volume":"375","author":"Richette","year":"2010","journal-title":"Gout Lancet"},{"key":"10.1016\/j.humimm.2012.05.004_b0015","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-2350-10-6","article-title":"An open access database of genome-wide association results","volume":"10","author":"Johnson","year":"2009","journal-title":"BMC Med Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0020","first-page":"1","article-title":"Strategies for pathway analysis from GWAS data","volume":"71","author":"Yaspan","year":"2011","journal-title":"Curr Protoc Hum Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0025","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/gepi.20395","article-title":"Using genome-wide pathway analysis to unravel the etiology of complex diseases","volume":"33","author":"Elbers","year":"2009","journal-title":"Genet Epidemiol"},{"key":"10.1016\/j.humimm.2012.05.004_b0030","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/nar\/gkr391","article-title":"ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework","volume":"39","author":"Zhang","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.humimm.2012.05.004_b0035","doi-asserted-by":"crossref","first-page":"e1000504","DOI":"10.1371\/journal.pgen.1000504","article-title":"Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations","volume":"5","author":"Kolz","year":"2009","journal-title":"PLoS Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0040","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/nar\/gkp896","article-title":"KEGG for representation and analysis of molecular networks involving diseases and drugs","volume":"38","author":"Kanehisa","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.humimm.2012.05.004_b0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The Gene Ontology Consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0050","doi-asserted-by":"crossref","first-page":"2938","DOI":"10.1093\/bioinformatics\/btn564","article-title":"SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap","volume":"24","author":"Johnson","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1016\/j.humimm.2012.05.004_b0055","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1056\/NEJMra0905980","article-title":"Genomewide association studies and assessment of the risk of disease","volume":"363","author":"Manolio","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humimm.2012.05.004_b0060","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00439-009-0676-z","article-title":"Strategies and issues in the detection of pathway enrichment in genome-wide association studies","volume":"126","author":"Hong","year":"2009","journal-title":"Hum Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0105","first-page":"1071","article-title":"Gene set analysis and network analysis for genome-wide association studies","volume":"9","author":"Pedroso","year":"2011","journal-title":"Cold Spring Harb Protoc"},{"key":"10.1016\/j.humimm.2012.05.004_b0070","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/ejhg.2011.57","article-title":"Gene set analysis of SNP data: benefits, challenges, and future directions","volume":"19","author":"Fridley","year":"2011","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0075","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1086\/522374","article-title":"Pathway-based approaches for analysis of genomewide association studies","volume":"81","author":"Wang","year":"2007","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0080","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jbspin.2010.02.027","article-title":"The genetic basis of hyperuricaemia and gout","volume":"78","author":"Merriman","year":"2011","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.humimm.2012.05.004_b0085","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/BOR.0b013e32833645e8","article-title":"Genetics of gout","volume":"22","author":"Choi","year":"2010","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.humimm.2012.05.004_b0090","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/ng.106","article-title":"SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout","volume":"40","author":"Vitart","year":"2008","journal-title":"Nat Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0095","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/ng.107","article-title":"SLC2A9 influences uric acid concentrations with pronounced sex-specific effects","volume":"40","author":"Doring","year":"2008","journal-title":"Nat Genet"},{"key":"10.1016\/j.humimm.2012.05.004_b0100","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1017\/S1461145710001446","article-title":"Pathway-based analysis of GWAS datasets: effective but caution required","volume":"14","author":"Jia","year":"2011","journal-title":"Int J Neuropsychopharmacol"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885912001188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885912001188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T05:52:40Z","timestamp":1542952360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885912001188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0198885912001188"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2012.05.004","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}