{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:27:24Z","timestamp":1793039244379,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.humimm.2013.06.034","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T00:03:04Z","timestamp":1372809784000},"page":"1474-1477","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Role of angiotensin II type 1 receptor-activating antibodies in solid organ transplantation"],"prefix":"10.1016","volume":"74","author":[{"given":"Nancy L.","family":"Reinsmoen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2013.06.034_b0005","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1161\/01.HYP.37.4.1047","article-title":"Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis","volume":"37","author":"Dzau","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.humimm.2013.06.034_b0010","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/TP.0b013e3181889748","article-title":"Humoral responses directed against non-human leukocyte antigens in solid-organ transplantation","volume":"86","author":"Dragun","year":"2008","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0015","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/00041552-200401000-00014","article-title":"The impact of renin\u2013angiotensin polymorphisms on physiological and pathophysiological processes in humans","volume":"13","author":"Miller","year":"2004","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.humimm.2013.06.034_b0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1161\/01.HYP.24.1.63","article-title":"Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension","volume":"24","author":"Bonnardeaux","year":"1994","journal-title":"Hypertension"},{"key":"10.1016\/j.humimm.2013.06.034_b0025","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1093\/ndt\/gfg304","article-title":"Kidney transplants, antibodies and rejection: is C4d a magic marker?","volume":"18","author":"Nickeleit","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.humimm.2013.06.034_b0030","first-page":"440","article-title":"Role of non-HLA antibodies in organ transplantation","volume":"17","author":"Dragun","year":"2012","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0035","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1097\/TP.0b013e3181fd97f1","article-title":"Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients","volume":"90","author":"Reinsmoen","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0040","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s00467-007-0452-z","article-title":"The role of angiotensin II type 1 receptor-activating antibodies in renal allograft vascular rejection","volume":"22","author":"Dragun","year":"2007","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.humimm.2013.06.034_b0045","first-page":"393A","article-title":"Screening of patients on waiting-list for a renal transplant for agonistic non-HLA antibodies targeting angiotensin II type 1 receptor (abstract)","volume":"17","author":"Slowinski","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.humimm.2013.06.034_b0050","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1056\/NEJMoa035717","article-title":"Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection","volume":"352","author":"Dragun","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humimm.2013.06.034_b0055","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1172\/JCI4106","article-title":"Patients with preeclampsia develop agonistic antibodies against the angiotensin AT1 receptor","volume":"103","author":"Wallukat","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.humimm.2013.06.034_b0060","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1097\/00004872-200018070-00017","article-title":"Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension","volume":"18","author":"Fu","year":"2000","journal-title":"J Hypertens"},{"key":"10.1016\/j.humimm.2013.06.034_b0065","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1146\/annurev.immunol.18.1.367","article-title":"Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression","volume":"18","author":"Mellor","year":"2000","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.humimm.2013.06.034_b0070","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1097\/TP.0b013e31816f612a","article-title":"Incidence and prediction of early antibody-mediated rejection due to non-human leukocyte antigen\u2013antibodies","volume":"85","author":"Amico","year":"2008","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0075","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1111\/j.1600-6143.2007.01855.x","article-title":"Value of posttransplant antibody tests in the evaluation of patients with renal graft dysfunction","volume":"7","author":"Scornik","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.humimm.2013.06.034_b0080","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/TP.0b013e318234b337","article-title":"Accelerated kidney transplant rejection and hypertensive encephalopathy in a pediatric patient associated with antibodies against angiotensin type 1 receptor and HLA class II","volume":"92","author":"Kelsch","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0085","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.jacc.2003.11.060","article-title":"Angiotensin II receptors from peritransplantation through first-year-post-transplantation and the risk of transplant coronary artery disease","volume":"43","author":"Yousufuddin","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.humimm.2013.06.034_b0090","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1161\/hy1201.100589","article-title":"Role of renin\u2013angiotensin system in vascular disease","volume":"38","author":"Ruiz-Ortega","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.humimm.2013.06.034_b0095","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1016\/j.healun.2006.09.012","article-title":"Increased expression of angiotensin II type 1 receptor (AGTR1) in heart transplant recipients with recurrent rejection","volume":"25","author":"Yamani","year":"2006","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.humimm.2013.06.034_b0100","first-page":"415","article-title":"International Union of Pharmacology. XXIII. The angiotensin II receptors","volume":"52","author":"de Gasparo","year":"2000","journal-title":"Pharmacol Rev."},{"key":"10.1016\/j.humimm.2013.06.034_b0105","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1146\/annurev.pharmtox.47.120505.105134","article-title":"Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease","volume":"47","author":"Schneider","year":"2007","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1016\/j.humimm.2013.06.034_b0110","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1161\/CIRCULATIONAHA.106.647149","article-title":"Prognostic impact of microvasculopathy on survival after heart transplantation\u2014evidence from 9713 endomyocardial biopsies","volume":"116","author":"Hiemann","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.humimm.2013.06.034_b0115","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/TP.0b013e3182692ad2","article-title":"Non-HLA antibodies targeting vascular receptors enhance alloimmune response and microvasculopathy after heart transplantation","volume":"94","author":"Hiemann","year":"2012","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0120","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0041-1345(98)01482-1","article-title":"Light microscopic biopsy findings after heart transplantation and possible links to development of graft vessel disease","volume":"31","author":"Hiemann","year":"1999","journal-title":"Transplant Proc"},{"key":"10.1016\/j.humimm.2013.06.034_b0125","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1111\/j.1600-6143.2009.02764.x","article-title":"Proinflammatory events are associated with significant increases in breadth and strength of HLA-specific antibody","volume":"9","author":"Locke","year":"2009","journal-title":"Am J Transplant"},{"issue":"Suppl.","key":"10.1016\/j.humimm.2013.06.034_b0175","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.humimm.2012.07.143","article-title":"Angiotensin II type 1 receptor sensitization in lung transplantation","volume":"73","author":"Eng","year":"2012","journal-title":"Hum Immunol"},{"issue":"S3","key":"10.1016\/j.humimm.2013.06.034_b0180","first-page":"170","article-title":"The impact of angiotensin II type 1 receptor auto-antibodies and early lung transplant outcomes","volume":"12","author":"Arnaoutakis","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1016\/j.humimm.2013.06.034_b0140","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/TP.0b013e3181e25a59","article-title":"Humoral autoimmunity and transplant vasculopathy: when allo is not enough","volume":"90","author":"Win","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0145","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1172\/JCI114282","article-title":"Molecular mimicry and myasthenia gravis: an autoantigenic site of acetycholine receptor \u03b1-subunit that has biologic activity and reacts immuno-chemically with herpes simplex virus","volume":"84","author":"Schwimmbeck","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1016\/j.humimm.2013.06.034_b0150","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1096\/fasebj.12.14.1551","article-title":"Functionally active cardiac antibodies in chronic Chagas\u2019 disease are specifically blocked by Trypanosoma cruzi antigens","volume":"12","author":"Masuda","year":"1998","journal-title":"FASEB J"},{"key":"10.1016\/j.humimm.2013.06.034_b0155","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jri.2006.08.084","article-title":"Is parvovirus B19 the cause for autoimmunity against angiotensin II type 1 receptor?","volume":"73","author":"Stepan","year":"2007","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.humimm.2013.06.034_b0160","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/TP.0b013e31821b60e9","article-title":"Clinical relevance and IgG subclass determination of non-HLA antibodies identified using endothelial cell precursors isolated from donor blood","volume":"92","author":"Jackson","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0165","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1097\/TP.0b013e3181d72091","article-title":"Chronic humoral rejection of human kidney allografts associates with broad autoantibody responses","volume":"89","author":"Porcheray","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2013.06.034_b0170","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/MOT.0b013e3283342780","article-title":"Antihuman leukocyte antigen antibody-induced autoimmunity: role in chronic rejection","volume":"15","author":"Nath","year":"2010","journal-title":"Curr Opin Organ Transplant"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885913001985?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885913001985?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T00:01:38Z","timestamp":1563321698000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885913001985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0198885913001985"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2013.06.034","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of angiotensin II type 1 receptor-activating antibodies in solid organ transplantation","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2013.06.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}