{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T23:31:20Z","timestamp":1781134280765,"version":"3.54.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.humimm.2014.06.006","type":"journal-article","created":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T21:18:44Z","timestamp":1403126324000},"page":"840-846","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Age-dependent association of mannose-binding lectin polymorphisms with the development of pulmonary tuberculosis in Viet Nam"],"prefix":"10.1016","volume":"75","author":[{"given":"Minako","family":"Hijikata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikumi","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thi Le","family":"Hang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pham Huu","family":"Thuong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Bang","family":"Tam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Shimbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsaku","family":"Sakurada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vu Cao","family":"Cuong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luu Thi","family":"Lien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Keicho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2014.06.006_b0005","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1600-065X.2010.00994.x","article-title":"For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection","volume":"240","author":"Dorhoi","year":"2011","journal-title":"Immunol Rev"},{"key":"10.1016\/j.humimm.2014.06.006_b0010","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.1128\/IAI.00443-12","article-title":"Innate immune gene polymorphisms in tuberculosis","volume":"80","author":"Azad","year":"2012","journal-title":"Infect Immun"},{"key":"10.1016\/j.humimm.2014.06.006_b0015","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.clim.2011.11.002","article-title":"Mannan-binding lectin deficiency \u2013 good news, bad news, doesn\u2019t matter?","volume":"143","author":"Heitzeneder","year":"2012","journal-title":"Clin Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0020","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1600-065X.2009.00789.x","article-title":"Mannose-binding lectin and innate immunity","volume":"230","author":"Ip","year":"2009","journal-title":"Immunol Rev"},{"key":"10.1016\/j.humimm.2014.06.006_b0025","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s00439-013-1273-8","article-title":"Genetic variants of complement genes ficolin-2, mannose-binding lectin and complement factor H are associated with leprosy in Han Chinese from Southwest China","volume":"132","author":"Zhang","year":"2013","journal-title":"Hum Genet"},{"key":"10.1016\/j.humimm.2014.06.006_b0030","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000228159","article-title":"Mannose-binding lectin deficiency and respiratory tract infection","volume":"2","author":"Eisen","year":"2010","journal-title":"J Innate Immun"},{"key":"10.1016\/j.humimm.2014.06.006_b0035","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1086\/377183","article-title":"Mannose-binding lectin polymorphisms in clinical tuberculosis","volume":"188","author":"S\u00f8borg","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0040","doi-asserted-by":"crossref","first-page":"e20908","DOI":"10.1371\/journal.pone.0020908","article-title":"Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis","volume":"6","author":"Thye","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.humimm.2014.06.006_b0045","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1574-695X.2006.00053.x","article-title":"Role of mannose binding lectin gene variants on its protein levels and macrophage phagocytosis with live Mycobacterium tuberculosis in pulmonary tuberculosis","volume":"46","author":"Selvaraj","year":"2006","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.humimm.2014.06.006_b0050","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1086\/596658","article-title":"Role played by human mannose-binding lectin polymorphisms in pulmonary tuberculosis","volume":"199","author":"Capparelli","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0055","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nri3259","article-title":"The immunological life cycle of tuberculosis","volume":"12","author":"Ernst","year":"2012","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0060","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.meegid.2011.08.010","article-title":"Old and new selective pressures on Mycobacterium tuberculosis","volume":"12","author":"Brites","year":"2012","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.humimm.2014.06.006_b0065","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1007\/s00439-011-1112-8","article-title":"Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese","volume":"131","author":"Hijikata","year":"2012","journal-title":"Hum Genet"},{"key":"10.1016\/j.humimm.2014.06.006_b0070","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ajhg.2013.01.013","article-title":"Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region","volume":"92","author":"Grant","year":"2013","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2014.06.006_b0075","first-page":"562","article-title":"A survey of tuberculosis prevalence in Hanoi, Vietnam","volume":"11","author":"Horie","year":"2007","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0080","doi-asserted-by":"crossref","first-page":"e71867","DOI":"10.1371\/journal.pone.0071867","article-title":"Primary drug-resistant tuberculosis in Hanoi, Viet Nam: present status and risk factors","volume":"8","author":"Hang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.humimm.2014.06.006_b0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/1471-2334-9-66","article-title":"Quality assessment of an interferon-gamma release assay for tuberculosis infection in a resource-limited setting","volume":"9","author":"Hang","year":"2009","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0090","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.humimm.2014.06.006_b0095","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/319501","article-title":"A new statistical method for haplotype reconstruction from population data","volume":"68","author":"Stephens","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humimm.2014.06.006_b0100","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0168-8278(98)80248-1","article-title":"Association of mannose-binding lectin gene haplotype LXPA and LYPB with interferon-resistant hepatitis C virus infection in Japanese patients","volume":"29","author":"Matsushita","year":"1998","journal-title":"J Hepatol"},{"key":"10.1016\/j.humimm.2014.06.006_b0105","first-page":"1098","article-title":"Sequence variations in the MBL gene and their relationship to pulmonary tuberculosis in the Chinese Han population","volume":"10","author":"Liu","year":"2006","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0110","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jaci.2006.01.031","article-title":"Functional polymorphisms in the mannan-binding lectin 2 gene: effect on MBL levels and otitis media","volume":"117","author":"Wiertsema","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0115","doi-asserted-by":"crossref","first-page":"767","DOI":"10.2147\/COPD.S33714","article-title":"Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease","volume":"7","author":"Albert","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0120","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/S1473-3099(07)70108-1","article-title":"Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development","volume":"7","author":"Gagneux","year":"2007","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.humimm.2014.06.006_b0125","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s10875-005-4702-1","article-title":"Mannose binding lectin acute phase activity in patients with severe infection","volume":"25","author":"Dean","year":"2005","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0130","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1365-2249.2009.03929.x","article-title":"Acute-phase responsiveness of mannose-binding lectin in community-acquired pneumonia is highly dependent upon MBL2 genotypes","volume":"156","author":"Herpers","year":"2009","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0135","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1006\/bmmb.1993.1052","article-title":"Human serum mannose binding protein (MBP): development of an enzyme-linked immunosorbent assay (ELISA) and determination of levels in serum from 1085 normal Japanese and in some body fluids","volume":"50","author":"Terai","year":"1993","journal-title":"Biochem Med Metab Biol"},{"key":"10.1016\/j.humimm.2014.06.006_b0140","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/j.1365-3083.2007.01991.x","article-title":"Biological variation in circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the influence of age, gender and physical exercise","volume":"66","author":"Ytting","year":"2007","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0145","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.0300-9475.2004.01392.x","article-title":"Serum mannose-binding lectin levels and mbl2 gene polymorphisms in different age and gender groups of southern Chinese adults","volume":"59","author":"Ip","year":"2004","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0150","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.molimm.2004.09.036","article-title":"Analysis of mannose-binding lectin 2 (MBL2) genotype and the serum protein levels in the Korean population","volume":"42","author":"Lee","year":"2005","journal-title":"Mol Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0155","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.4049\/jimmunol.159.6.2979","article-title":"Induction of TNF-alpha in human peripheral blood mononuclear cells by the mannoprotein of Cryptococcus neoformans involves human mannose binding protein","volume":"159","author":"Chaka","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0160","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.4049\/jimmunol.175.3.1785","article-title":"Mannose-binding lectin recognizes peptidoglycan via the N-acetyl glucosamine moiety, and inhibits ligand-induced proinflammatory effect and promotes chemokine production by macrophages","volume":"175","author":"Nadesalingam","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0165","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1084\/jem.20071164","article-title":"Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome","volume":"205","author":"Ip","year":"2008","journal-title":"J Exp Med"},{"key":"10.1016\/j.humimm.2014.06.006_b0170","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.humimm.2010.07.011","article-title":"Dendritic cells previously exposed to mannan-binding lectin enhance cytokine production in allogeneic mononuclear cell cultures","volume":"71","author":"MacDonald","year":"2010","journal-title":"Hum Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2172-12-1","article-title":"Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide","volume":"12","author":"Wang","year":"2011","journal-title":"BMC Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0180","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/cmi.2011.1","article-title":"Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine secretion from THP-1 cells","volume":"8","author":"Wang","year":"2011","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.humimm.2014.06.006_b0185","doi-asserted-by":"crossref","first-page":"e72505","DOI":"10.1371\/journal.pone.0072505","article-title":"Mannose-binding lectin inhibits monocyte proliferation through transforming growth factor-\u03b21 and p38 signaling pathways","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.humimm.2014.06.006_b0190","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/jhg.2012.35","article-title":"Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis","volume":"57","author":"Mahasirimongkol","year":"2012","journal-title":"J Hum Genet"},{"key":"10.1016\/j.humimm.2014.06.006_b0195","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-1-4614-6111-1_2","article-title":"Host-pathogen specificity in tuberculosis","volume":"783","author":"Di Pietrantonio","year":"2013","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.humimm.2014.06.006_b0200","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/sj.gene.6364116","article-title":"Sequence analysis of the mannose-binding lectin (MBL2) gene reveals a high degree of heterozygosity with evidence of selection","volume":"5","author":"Bernig","year":"2004","journal-title":"Genes Immun"},{"key":"10.1016\/j.humimm.2014.06.006_b0205","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.tim.2011.07.002","article-title":"A role for systems epidemiology in tuberculosis research","volume":"19","author":"Comas","year":"2011","journal-title":"Trends Microbiol"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885914001700?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885914001700?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:49:53Z","timestamp":1759319393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885914001700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":41,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0198885914001700"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2014.06.006","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age-dependent association of mannose-binding lectin polymorphisms with the development of pulmonary tuberculosis in Viet Nam","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2014.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}