{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T13:10:49Z","timestamp":1791205849379,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Higher Education and Scientific Research"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.humimm.2016.01.008","type":"journal-article","created":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T05:08:06Z","timestamp":1452488886000},"page":"325-329","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Nonclassical human leukocyte antigen (HLA-G, HLA-E, and HLA-F) in coronary artery disease"],"prefix":"10.1016","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1170-4957","authenticated-orcid":false,"given":"Ines","family":"Zidi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najla","family":"Kharrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania","family":"Abdelhedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amna Ben","family":"Hassine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Baligh","family":"Laaribi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza Ben","family":"Yahia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nouha Bouayed","family":"Abdelmoula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Abid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Rebai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2016.01.008_b0005","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1161\/CIRCULATIONAHA.104.482570","article-title":"Biomarkers of cardiovascular disease: molecular basis and practical considerations","volume":"113","author":"Vasan","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.humimm.2016.01.008_b0010","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/biof.1024","article-title":"Inflammatory markers in coronary artery disease","volume":"38","author":"Ikonomidis","year":"2012","journal-title":"BioFactors"},{"key":"10.1016\/j.humimm.2016.01.008_b0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.5493\/wjem.v5.i1.21","article-title":"Consolidated and emerging inflammatory markers in coronary artery disease","volume":"5","author":"Lubrano","year":"2015","journal-title":"World J. Exp. Med."},{"key":"10.1016\/j.humimm.2016.01.008_b0020","doi-asserted-by":"crossref","DOI":"10.2174\/0929867322666150415125828","article-title":"Circulating biomarkers determining inflammation in atherosclerosis progression","author":"Siasos","year":"2015","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.humimm.2016.01.008_b0025","article-title":"Meta-analysis of associations between functional HLA-G polymorphisms and susceptibility to systemic lupus erythematosus and rheumatoid arthritis","author":"Lee","year":"2014","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.humimm.2016.01.008_b0030","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/tan.12311","article-title":"HLA-G +3142 polymorphism as a susceptibility marker in two rheumatoid arthritis populations in Brazil","volume":"83","author":"Veit","year":"2014","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2016.01.008_b0035","doi-asserted-by":"crossref","first-page":"657625","DOI":"10.1155\/2014\/657625","article-title":"Some basic aspects of HLA-G biology","volume":"2014","author":"Alegre","year":"2014","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.humimm.2016.01.008_b0040","first-page":"359748","article-title":"The dual role of HLA-G in cancer","author":"Rouas-Freiss","year":"2014","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.humimm.2016.01.008_b0045","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.ejca.2013.10.018","article-title":"Human leucocyte antigen-G polymorphisms are associated with cervical squamous cell carcinoma risk in Taiwanese women","volume":"50","author":"Yang","year":"2014","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.humimm.2016.01.008_b0050","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.humimm.2012.12.014","article-title":"Can HLA-G polymorphisms predict the development of cardiac allograft vasculopathy?","volume":"74","author":"Mociornita","year":"2013","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0055","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1002\/eji.1830270517","article-title":"The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9","volume":"27","author":"Braud","year":"1997","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0060","doi-asserted-by":"crossref","first-page":"D1222","DOI":"10.1093\/nar\/gks949","article-title":"The IMGT\/HLA database","volume":"41","author":"Robinson","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.humimm.2016.01.008_b0065","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/0198-8859(92)90069-Y","article-title":"Polymorphism at the HLA-E locus predates most HLA-A and -B polymorphism","volume":"33","author":"Geraghty","year":"1992","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0070","doi-asserted-by":"crossref","first-page":"907092","DOI":"10.1155\/2010\/907092","article-title":"The emerging role of HLA-E-restricted CD8+ T lymphocytes in the adaptive immune response to pathogens and tumors","volume":"2010","author":"Pietra","year":"2010","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.humimm.2016.01.008_b0075","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1002\/1521-4141(200012)30:12<3552::AID-IMMU3552>3.0.CO;2-L","article-title":"Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors","volume":"30","author":"Lepin","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0080","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/iji.12047","article-title":"Characterization of HLA-F polymorphism in four distinct populations in Mainland China","volume":"40","author":"Pan","year":"2013","journal-title":"Int. J. Immunogenet."},{"key":"10.1016\/j.humimm.2016.01.008_b0085","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1016\/j.transproceed.2014.07.010","article-title":"Impact of human leukocyte antigen molecules E, F, and G on the outcome of transplantation","volume":"46","author":"Pab\u00f3n","year":"2014","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.humimm.2016.01.008_b0090","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.humimm.2011.08.016","article-title":"Human leukocyte antigen-G is upregulated in heart failure patients: a potential novel biomarker","volume":"72","author":"Almasood","year":"2011","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0095","series-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook","year":"2001"},{"key":"10.1016\/j.humimm.2016.01.008_b0100","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/978-1-61779-842-9_8","article-title":"Molecular typing of HLA-E","volume":"882","author":"Lauterbach","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.humimm.2016.01.008_b0105","unstructured":"<http:\/\/hla.alleles.org\/data\/txt\/f_gen.txt> (Access 10.07.2015)."},{"key":"10.1016\/j.humimm.2016.01.008_b0110","doi-asserted-by":"crossref","first-page":"143","DOI":"10.4103\/0974-1208.92289","article-title":"Role of 14-bp deletion\/insertion polymorphism in exon 8 of the HLA-G gene in recurrent spontaneous abortion patients","volume":"4","author":"Shankarkumar","year":"2011","journal-title":"J. Hum. Reprod. Sci."},{"key":"10.1016\/j.humimm.2016.01.008_b0115","doi-asserted-by":"crossref","first-page":"R211","DOI":"10.1186\/cc11845","article-title":"Polymorphic variants in exon 8 at the 3\u2032 UTR of the HLA-G gene are associated with septic shock in critically ill patients","volume":"16","author":"Graebin","year":"2012","journal-title":"Crit. Care"},{"key":"10.1016\/j.humimm.2016.01.008_b0120","unstructured":"<http:\/\/pngu.mgh.harvard.edu\/~purcell\/plink\/> (Access 10.07.2015)."},{"key":"10.1016\/j.humimm.2016.01.008_b0125","first-page":"196","article-title":"Association analysis of interleukin gene polymorphisms in autoimmune thyroid diseases in the Tunisian population","volume":"18","author":"Kammoun-Krichen","year":"2007","journal-title":"Eur. Cytokine Netw."},{"key":"10.1016\/j.humimm.2016.01.008_b0130","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/gene.2013.67","article-title":"Worldwide genetic variation at the 3\u2032 untranslated region of the HLA-G gene: balancing selection influencing genetic diversity","volume":"15","author":"Sabbagh","year":"2014","journal-title":"Genes Immun."},{"key":"10.1016\/j.humimm.2016.01.008_b0135","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.healun.2011.01.726","article-title":"The 14-bp deletion in the HLA-G gene indicates a low risk for acute cellular rejection in heart transplant recipients","volume":"30","author":"Twito","year":"2011","journal-title":"J. Heart Lung Transplant."},{"key":"10.1016\/j.humimm.2016.01.008_b0140","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.exphem.2014.11.007","article-title":"Do human leukocyte antigen E polymorphisms influence graft-versus-leukemia after allogeneic hematopoietic stem cell transplantation?","volume":"43","author":"Hosseini","year":"2015","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.humimm.2016.01.008_b0145","doi-asserted-by":"crossref","DOI":"10.1007\/s00011-015-0821-1","article-title":"Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk","author":"Merhi","year":"2015","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.humimm.2016.01.008_b0150","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12967-015-0457-5","article-title":"Characterization of a novel endothelial biosensor assay reveals increased cumulative serum inflammatory potential in stabilized coronary artery disease patients","volume":"13","author":"Cung","year":"2015","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.humimm.2016.01.008_b0155","doi-asserted-by":"crossref","first-page":"448","DOI":"10.2174\/187152812803590037","article-title":"New insights into HLA-G and inflammatory diseases","volume":"11","author":"Rizzo","year":"2012","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/j.humimm.2016.01.008_b0160","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.humimm.2012.11.030","article-title":"Analyzing HLA-G polymorphisms in children from women with scleroderma","volume":"74","author":"Picard","year":"2013","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0165","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.trim.2008.11.001","article-title":"Tolerance versus immune response \u2013 microRNAs as important elements in the regulation of the HLA-G gene expression","volume":"20","author":"Veit","year":"2009","journal-title":"Transpl. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0170","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.humimm.2012.08.005","article-title":"Role of HLA-G 14bp deletion\/insertion and +3142C>G polymorphisms in the production of sHLA-G molecules in relapsing-remitting multiple sclerosis","volume":"73","author":"Rizzo","year":"2012","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0175","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1136\/annrheumdis-2012-201334","article-title":"How early in the course of rheumatoid arthritis does the excess cardiovascular risk appear?","volume":"71","author":"Kerola","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.humimm.2016.01.008_b0180","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1007\/s10753-014-9890-5","article-title":"Serum-soluble HLA-G is associated with specific IgE in patients with allergic rhinitis and asthma","volume":"37","author":"Ciprandi","year":"2014","journal-title":"Inflammation"},{"key":"10.1016\/j.humimm.2016.01.008_b0185","doi-asserted-by":"crossref","first-page":"592","DOI":"10.3389\/fimmu.2014.00592","article-title":"HLA-G molecules in autoimmune diseases and infections","volume":"5","author":"Rizzo","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.humimm.2016.01.008_b0190","first-page":"1141","article-title":"Association between two polymorphisms in the HLA-G gene and angiographic coronary artery disease","volume":"5","author":"Boiocchi","year":"2012","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.humimm.2016.01.008_b0195","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.cellimm.2014.10.003","article-title":"Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients","volume":"293","author":"Guo","year":"2015","journal-title":"Cell. Immunol."}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885916000094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885916000094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T03:58:31Z","timestamp":1537070311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885916000094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S0198885916000094"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2016.01.008","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nonclassical human leukocyte antigen (HLA-G, HLA-E, and HLA-F) in coronary artery disease","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2016.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}