{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:29:21Z","timestamp":1780352961109,"version":"3.54.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.humimm.2016.04.005","type":"journal-article","created":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T11:44:02Z","timestamp":1459856642000},"page":"1030-1036","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Completion of HLA protein sequences by automated homology-based nearest-neighbor extrapolation of HLA database sequences"],"prefix":"10.1016","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1689-8383","authenticated-orcid":false,"given":"Kirsten","family":"Geneugelijk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Niemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talitha","family":"de Hoop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Spierings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2016.04.005_b0005","unstructured":"The IMGT\/HLA database. (accessed October 16th, 2015)."},{"key":"10.1016\/j.humimm.2016.04.005_b0010","doi-asserted-by":"crossref","first-page":"4576","DOI":"10.1182\/blood-2007-06-097386","article-title":"High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation","volume":"110","author":"Lee","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0015","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1182\/blood-2009-01-200378","article-title":"Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation","volume":"114","author":"Crocchilo","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0020","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1182\/blood-2004-03-0803","article-title":"Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome","volume":"104","author":"Fomenberg","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0025","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1182\/blood-2013-02-482547","article-title":"High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysis","volume":"122","author":"Furst","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0030","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1182\/blood-2007-02-072405","article-title":"High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism","volume":"110","author":"Kawase","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0035","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1182\/blood-2008-08-171934","article-title":"HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism","volume":"113","author":"Kawase","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0040","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1182\/blood.V99.11.4200","article-title":"The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors","volume":"99","author":"Morishima","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0045","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1182\/blood-2014-10-604785","article-title":"Biological significance of HLA locus matching in unrelated donor bone marrow transplantation","volume":"125","author":"Morishima","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.humimm.2016.04.005_b0050","first-page":"21","article-title":"HLA-DPB1 mismatch and acute graft-versus host disease in HLA-identical sibling donors","volume":"12","author":"Mosaad","year":"2005","journal-title":"Egypt. J. Immunol."},{"key":"10.1016\/j.humimm.2016.04.005_b0055","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1111\/j.1600-6143.2011.03640.x","article-title":"Revisiting traditional risk factors for rejection and graft loss after kidney transplantation","volume":"11","author":"Dunn","year":"2011","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.humimm.2016.04.005_b0060","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/TP.0b013e31821cded7","article-title":"Consideration of donor age and human leukocyte antigen matching in the setting of multiple potential living kidney donors","volume":"92","author":"Rizzari","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.humimm.2016.04.005_b0065","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1001\/archsurg.2011.147","article-title":"HLA-DR matching in organ allocation: balance between waiting time and rejection in pediatric kidney transplantation","volume":"146","author":"Vu","year":"2011","journal-title":"Arch. Surg."},{"key":"10.1016\/j.humimm.2016.04.005_b0070","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1056\/NEJM199012273232607","article-title":"Bone marrow-allograft rejection by T lymphocytes recognizing a single amino acid difference in HLA-B44","volume":"323","author":"Fleischhauer","year":"1990","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.humimm.2016.04.005_b0075","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1084\/jem.20030066","article-title":"A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition","volume":"198","author":"Macdonald","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.humimm.2016.04.005_b0080","doi-asserted-by":"crossref","first-page":"D423","DOI":"10.1093\/nar\/gku1161","article-title":"The IPD and IMGT\/HLA database: allele variant databases","volume":"43","author":"Robinson","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.humimm.2016.04.005_b0085","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0041-1345(00)02108-4","article-title":"HLAMMATCHMAKER: a molecularly based donor selection algorithm for highly alloimmunized patients","volume":"33","author":"Duquesnoy","year":"2001","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.humimm.2016.04.005_b0090","doi-asserted-by":"crossref","first-page":"159479","DOI":"10.1155\/2014\/159479","article-title":"Predicting alloreactivity in transplantation","volume":"2014","author":"Geneugelijk","year":"2014","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.humimm.2016.04.005_b0095","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.humimm.2006.08.001","article-title":"A structurally based approach to determine HLA compatibility at the humoral immune level","volume":"67","author":"Duquesnoy","year":"2006","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.04.005_b0100","unstructured":"SYFPEITHI database. <http:\/\/www.syfpeithi.de\/bin\/MHCServer.dll\/FindYourMotif.htm>, (accessed September 2015)."},{"key":"10.1016\/j.humimm.2016.04.005_b0105","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0198-8859(02)00382-8","article-title":"HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. I. Description of the algorithm","volume":"63","author":"Duquesnoy","year":"2002","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.04.005_b0110","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.bbmt.2008.07.001","article-title":"HLAMatchmaker-defined triplet matching is not associated with better survival rates of patients with class I HLA allele mismatched hematopoietic cell transplants from unrelated donors","volume":"14","author":"Duquesnoy","year":"2008","journal-title":"Biology Blood Marrow Transplant."},{"key":"10.1016\/j.humimm.2016.04.005_b0115","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.humimm.2013.06.025","article-title":"Six-locus high resolution HLA haplotype frequencies derived from mixed-resolution DNA typing for the entire US donor registry","volume":"74","author":"Gragert","year":"2013","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2016.04.005_b0120","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1034\/j.1399-0039.2003.00097.x","article-title":"Use of a neural network to assign serologic specificities to HLA-A, -B and -DRB1 allelic products","volume":"62","author":"Maiers","year":"2003","journal-title":"Tissue Antigens"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885916300453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885916300453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T13:53:06Z","timestamp":1536846786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885916300453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0198885916300453"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2016.04.005","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Completion of HLA protein sequences by automated homology-based nearest-neighbor extrapolation of HLA database sequences","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2016.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}