{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T12:11:17Z","timestamp":1772799077584,"version":"3.50.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.humimm.2020.01.005","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T01:07:34Z","timestamp":1580432854000},"page":"85-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Is the TAP2 single nucleotide polymorphism rs241447 truly associated with psoriasis in Poles?"],"prefix":"10.1016","volume":"81","author":[{"given":"Andrzej","family":"Wi\u015bniewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"Wilczy\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Jasek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanda","family":"Niepiek\u0142o-Miniewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izabela","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0141ukasz","family":"Matusiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneta","family":"Szczerkowska\u2011Dobosz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Ku\u015bnierczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2020.01.005_b0005","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0140-6736(14)61909-7","article-title":"Psoriasis","volume":"386","author":"Boehncke","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.humimm.2020.01.005_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coi.2017.07.007","article-title":"Psoriasis: a mixed autoimmune and autoinflammatory disease","volume":"49","author":"Liang","year":"2017","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.humimm.2020.01.005_b0015","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.autrev.2017.07.011","article-title":"Autoimmune aspects of psoriasis: Heritability and autoantigens","volume":"16","author":"Prinz","year":"2017","journal-title":"Autoimm. Rev."},{"key":"10.1016\/j.humimm.2020.01.005_b0020","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.3390\/ijms18122526","article-title":"The Genetic Basis of Psoriasis","volume":"18","author":"Capon","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.humimm.2020.01.005_b0025","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0165-2478(02)00212-2","article-title":"Strong association of HLA-Cw6 allele with juvenile psoriasis in Polish patients","volume":"85","author":"\u0141uszczek","year":"2003","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.humimm.2020.01.005_b0030","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.humimm.2017.11.010","article-title":"The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset","volume":"79","author":"Wi\u015bniewski","year":"2018","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.humimm.2020.01.005_b0035","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1046\/j.1365-2370.2000.00186.x","article-title":"Polymorphism of LMP2, TAP1, LMP7 and TAP2 in Brazilian Amerindians and Caucasoids: implications for the evolution of allelic and haplotypic diversity","volume":"27","author":"Faucz","year":"2000","journal-title":"Eur. J. Immunogenet."},{"key":"10.1016\/j.humimm.2020.01.005_b0040","doi-asserted-by":"crossref","first-page":"270","DOI":"10.2337\/db06-0865","article-title":"Genetic control of alternative splicing in the TAP2 gene: possible implication in the genetics of type 1 diabetes","volume":"56","author":"Qu","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.humimm.2020.01.005_b0045","first-page":"1","article-title":"A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition","volume":"363","author":"Stratikos","year":"2014","journal-title":"Front. Oncol."},{"key":"10.1016\/j.humimm.2020.01.005_b0050","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0198-8859(98)00046-9","article-title":"Analysis of HLA class II and TAP alleles in Japanese patients with psoriasis vulgaris","volume":"59","author":"Saeki","year":"1998","journal-title":"Hum. Immunol."},{"issue":"4","key":"10.1016\/j.humimm.2020.01.005_b0055","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0198-8859(94)90029-9","article-title":"Analysis of TAP2 and HLA-DP gene polymorphism in psoriasis","volume":"40","author":"Fakler","year":"1994","journal-title":"Hum. Immunol."},{"issue":"1","key":"10.1016\/j.humimm.2020.01.005_b0060","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0198-8859(96)00156-5","article-title":"zum B\u00fcschenfelde, E. M\u00e4rker-Hermann, TAP-polymorphisms in juvenile onset psoriasis and psoriatic arthritis","volume":"51","author":"H\u00f6hler","year":"1996","journal-title":"Hum. Immunol."},{"issue":"6","key":"10.1016\/j.humimm.2020.01.005_b0065","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/sj.gene.6364404","article-title":"Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype","volume":"8","author":"Kr\u00e4mer","year":"2007","journal-title":"Genes Immun."},{"issue":"4","key":"10.1016\/j.humimm.2020.01.005_b0070","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1046\/j.1523-1747.2003.12091.x","article-title":"Association of TAP and HLA-DM genes with psoriasis in Koreans","volume":"120","author":"Pyo","year":"2003","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.humimm.2020.01.005_b0075","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1600-065X.1999.tb01399.x","article-title":"Genomics of the major histocompatibility complex: haplotypes, duplication, retroviruses and disease","volume":"167","author":"Dawkins","year":"1999","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.humimm.2020.01.005_b0080","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/tan.13429","article-title":"The complexity and diversity of major histocompatibility complex challenge disease association studies","volume":"93","author":"Lokki","year":"2019","journal-title":"HLA"},{"issue":"4","key":"10.1016\/j.humimm.2020.01.005_b0085","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1399-0039.2005.00379.x","article-title":"Nomenclature for factors of the HLA system, 2004","volume":"65","author":"Marsh","year":"2005","journal-title":"Tissue Antig."},{"issue":"7","key":"10.1016\/j.humimm.2020.01.005_b0090","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0198-8859(03)00079-X","article-title":"ZVITAMBO Study Group, New transporter associated with antigen processing (TAP-2) polymorphisms in the Shona people of Zimbabwe","volume":"64","author":"Lajoie","year":"2003","journal-title":"Hum. Immunol."},{"issue":"8","key":"10.1016\/j.humimm.2020.01.005_b0095","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.humimm.2004.05.013","article-title":"Is TAP2*0102 allele involved in insulin-dependent diabetes mellitus (type 1) protection?","volume":"65","author":"Cesari","year":"2004","journal-title":"Hum. Immunol."},{"issue":"1","key":"10.1016\/j.humimm.2020.01.005_b0100","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1900\/RDS.2005.2.40","article-title":"Genetic susceptibility to type 1 diabetes in the intracellular pathway of antigen processing \u2013 a subject review and cross-study comparison","volume":"2","author":"Sia","year":"2005","journal-title":"Rev. Diabet. Stud."},{"key":"10.1016\/j.humimm.2020.01.005_b0105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.molimm.2018.03.024","article-title":"Role of genetic variations on MHC class I antigen-processing genes in human cancer and viral-mediated diseases","volume":"113","author":"D'Alicandro","year":"2019","journal-title":"Mol. Immunol."},{"issue":"10","key":"10.1016\/j.humimm.2020.01.005_b0110","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.humimm.2011.07.304","article-title":"Association of TAP 1 and 2 gene polymorphisms with human immunodeficiency virus-tuberculosis co-infection","volume":"72","author":"Sunder","year":"2011","journal-title":"Hum Immunol."},{"issue":"9","key":"10.1016\/j.humimm.2020.01.005_b0115","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.7314\/APJCP.2013.14.9.5213","article-title":"Association of TAP1 and TAP2 gene polymorphisms with hematological malignancies","volume":"14","author":"Ozbas-Gerceker","year":"2013","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"2","key":"10.1016\/j.humimm.2020.01.005_b0120","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1155\/2013\/368732","article-title":"Association of TAP gene polymorphisms and risk of cervical intraepithelial neoplasia","volume":"35","author":"Natter","year":"2013","journal-title":"Dis Markers."},{"issue":"4","key":"10.1016\/j.humimm.2020.01.005_b0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123513","article-title":"Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection","volume":"10","author":"Huang","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.humimm.2020.01.005_b0130","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1746-1596-9-129","article-title":"Significant association between TAP2 polymorphisms and rheumatoid arthritis: a meta-analysis","volume":"27","author":"Dai","year":"2014","journal-title":"Diagn. Pathol."},{"issue":"9","key":"10.1016\/j.humimm.2020.01.005_b0135","doi-asserted-by":"crossref","first-page":"15867","DOI":"10.1002\/jcb.28857","article-title":"Quantitative assessment of the association between TAP2 rs241447 polymorphism and cancer risk","volume":"120","author":"Liu","year":"2019","journal-title":"J. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.humimm.2020.01.005_b0140","first-page":"62","article-title":"Association of TAP1 and TAP2 gene polymorphisms with susceptibility to pulmonary tuberculosis","volume":"15","author":"Naderi","year":"2016","journal-title":"Iran J. Allergy Asthma Immunol."},{"key":"10.1016\/j.humimm.2020.01.005_b0145","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11010-019-03649-x","article-title":"Analysis of transporter associated with antigen presentation (TAP) genes polymorphisms with HIV-1 infection","author":"Abitew","year":"2020","journal-title":"Mol. Cell. Biochem."},{"issue":"2","key":"10.1016\/j.humimm.2020.01.005_b0150","doi-asserted-by":"crossref","first-page":"852","DOI":"10.4049\/jimmunol.162.2.852","article-title":"Novel splicing of the human MHC-encoded peptide transporter confers unique properties","volume":"162","author":"Yan","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.humimm.2020.01.005_b0155","unstructured":"https:\/\/ldlink.nci.nih.gov\/."},{"issue":"2","key":"10.1016\/j.humimm.2020.01.005_b0160","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/em.22159","article-title":"A functional SNP in the 3'-UTR of TAP2 gene interacts with microRNA hsa-miR-1270 to suppress the gene expression","volume":"59","author":"Knox","year":"2018","journal-title":"Environ. Mol. Mutagen."},{"issue":"3","key":"10.1016\/j.humimm.2020.01.005_b0165","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000083509","article-title":"The psoriasis area and severity index is the adequate criterion to define severity in chronic plaque-type psoriasis","volume":"210","author":"Schmitt","year":"2005","journal-title":"Dermatology"},{"key":"10.1016\/j.humimm.2020.01.005_b0170","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s00438-018-1435-4","article-title":"HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1\/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis","volume":"293","author":"Wi\u015bniewski","year":"2018","journal-title":"Molec. Genet. Genomics"},{"issue":"1","key":"10.1016\/j.humimm.2020.01.005_b0175","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1399-0039.1994.tb02291.x","article-title":"Ryder, HLA and disease associations: detecting the strongest association","volume":"43","author":"Svejgaard","year":"1994","journal-title":"Tissue Antigens"},{"issue":"3","key":"10.1016\/j.humimm.2020.01.005_b0180","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1046\/j.1365-2370.2003.00393.x","article-title":"Comparison of TAP2 frequencies in type 1 diabetes patients and healthy controls from three ethnic groups indicates an African origin for the TAP2 G allele","volume":"30","author":"Hoarau","year":"2003","journal-title":"Eur. J. Immunogenet."},{"issue":"2","key":"10.1016\/j.humimm.2020.01.005_b0185","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/0198-8859(95)00062-9","article-title":"Family study of linkage disequilibrium between TAP2 transporter and HLA class II genes. Absence of TAP2 contribution to association with insulin-dependent diabetes mellitus","volume":"44","author":"Caillat-Zucman","year":"1995","journal-title":"Hum. Immunol."},{"issue":"1","key":"10.1016\/j.humimm.2020.01.005_b0190","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0198-8859(94)00124-9","article-title":"TAP2 association with insulin-dependent diabetes mellitus is secondary to HLA-DQB1","volume":"43","author":"Jackson","year":"1995","journal-title":"Hum. Immunol."},{"issue":"5","key":"10.1016\/j.humimm.2020.01.005_b0195","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1002\/eji.1830230511","article-title":"Linkage disequilibrium between TAP2 variants and HLA class II alleles; no primary association between TAP2 variants and insulin-dependent diabetes mellitus","volume":"23","author":"R\u00f8nningen","year":"1993","journal-title":"Eur. J. Immunol."},{"issue":"3","key":"10.1016\/j.humimm.2020.01.005_b0200","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2370.1997.00266.x","article-title":"Polymorphisms of TAP1 and TAP2 genes in German patients with type 1 diabetes mellitus","volume":"24","author":"Rau","year":"1997","journal-title":"Eur. J. Immunogenet."},{"issue":"4","key":"10.1016\/j.humimm.2020.01.005_b0205","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/1523-1747.ep12345600","article-title":"Familial juvenile onset psoriasis is associated with the human leukocyte antigen (HLA) class I side of the extended haplotype Cw6-B57-DRB1*0701-DQA1*0201-DQB1*0303: a population- and family-based study","volume":"106","author":"Schmitt-Egenolf","year":"1996","journal-title":"J. Invest. Dermatol."},{"issue":"2","key":"10.1016\/j.humimm.2020.01.005_b0210","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1399-0039.1996.tb02612.x","article-title":"Linkage disequilibrium between HLA class II (DR, DQ, DP) and antigen processing (LMP, TAP, DM) genes of the major histocompatibility complex","volume":"48","author":"Djilali-Saiah","year":"1996","journal-title":"Tissue Antigens"},{"issue":"6","key":"10.1016\/j.humimm.2020.01.005_b0215","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1034\/j.1399-0039.2000.560602.x","article-title":"New polymorphic microsatellite markers in the human MHC class II region","volume":"56","author":"Matsuzaka","year":"2000","journal-title":"Tissue Antigens"},{"issue":"7","key":"10.1016\/j.humimm.2020.01.005_b0220","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/gene.2008.58","article-title":"MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2","volume":"9","author":"Ivansson","year":"2008","journal-title":"Genes Immun."},{"key":"10.1016\/j.humimm.2020.01.005_b0225","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/sj.jid.5700118","article-title":"Distinct clinical differences between HLA-Cw*0602 positive and negative psoriasis patients - an analysis of 1019 HLA-C- and HLA-B-typed patients","volume":"126","author":"Gudjonsson","year":"2006","journal-title":"J. Invest. Dermatol."},{"issue":"5","key":"10.1016\/j.humimm.2020.01.005_b0230","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.jbspin.2015.09.004","article-title":"Age at disease onset may help to further characterize the disease phenotype in psoriatic arthritis","volume":"83","author":"Alonso","year":"2016","journal-title":"Joint. Bone Spine."}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885919313254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885919313254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:51:58Z","timestamp":1759319518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885919313254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":46,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0198885919313254"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2020.01.005","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is the TAP2 single nucleotide polymorphism rs241447 truly associated with psoriasis in Poles?","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2020.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}