{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:24:20Z","timestamp":1777865060487,"version":"3.51.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","award":["09\/796(0065)\/2016-EMR-I"],"award-info":[{"award-number":["09\/796(0065)\/2016-EMR-I"]}],"id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology","doi-asserted-by":"publisher","award":["BT\/22\/NE\/2011"],"award-info":[{"award-number":["BT\/22\/NE\/2011"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.humimm.2022.02.006","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T17:08:05Z","timestamp":1646240885000},"page":"453-457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["A comparative study on regulation of HLA-G expression in bad obstetric history and in head and neck squamous cell carcinoma from Northeast India"],"prefix":"10.1016","volume":"83","author":[{"given":"Mayuri","family":"Bora","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelanjana","family":"Sarmah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhaswatee","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munindra","family":"Narayan Baruah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gitanjali","family":"Deka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumita","family":"Gogoi Hazarika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashi","family":"Baruah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humimm.2022.02.006_b0005","series-title":"Advances in Immunology","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0065-2776(03)81006-4","article-title":"HLA-G molecules: From maternal\u2013fetal tolerance to tissue acceptance","author":"Carosella","year":"2003"},{"key":"10.1016\/j.humimm.2022.02.006_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/297073","article-title":"HLA-G as a tolerogenic molecule in transplantation and pregnancy","volume":"2014","author":"Rebmann","year":"2014","journal-title":"J. Immunol. Res."},{"issue":"12","key":"10.1016\/j.humimm.2022.02.006_b0015","doi-asserted-by":"crossref","first-page":"4528","DOI":"10.3390\/ijms21124528","article-title":"HLA-G: A New Immune Checkpoint in Cancer?","volume":"21","author":"Krijgsman","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.humimm.2022.02.006_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/734068","article-title":"Transcriptional and posttranscriptional regulations of the HLA-G gene","volume":"2014","author":"Castelli","year":"2014","journal-title":"J. Immunol. Res."},{"issue":"9","key":"10.1016\/j.humimm.2022.02.006_b0025","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/molehr\/gav037","article-title":"Hypermethylation of the HLA-G promoter is associated with preeclampsia","volume":"21","author":"Tang","year":"2015","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.humimm.2022.02.006_b0030","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.698438","article-title":"HLA-G 3\u2019UTR Polymorphisms Are Linked to Susceptibility and Survival in Spanish Gastric Adenocarcinoma Patients","volume":"12","author":"Vaquero-Yuste","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.humimm.2022.02.006_b0035","doi-asserted-by":"crossref","first-page":"e0178549","DOI":"10.1371\/journal.pone.0178549","article-title":"Identification of key microRNAs and genes in preeclampsia by bioinformatics analysis","volume":"12","author":"Luo","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.humimm.2022.02.006_b0040","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.placenta.2016.08.086","article-title":"Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a\/152 in the placenta of preeclamptic rats and HTR-8 cells","volume":"46","author":"Yang","year":"2016","journal-title":"Placenta"},{"issue":"9","key":"10.1016\/j.humimm.2022.02.006_b0045","first-page":"3553","article-title":"Correlation of MiR-152 expression with VEGF expression in placental tissue of preeclampsia rat and its influence on apoptosis of trophoblast cells","volume":"23","author":"Zhang","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"8","key":"10.1016\/j.humimm.2022.02.006_b0050","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1261\/rna.060962.117","article-title":"3\u2019 UTR G-quadruplexes regulate miRNA binding","volume":"23","author":"Rouleau","year":"2017","journal-title":"RNA"},{"issue":"1","key":"10.1016\/j.humimm.2022.02.006_b0055","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/s41467-020-14404-y","article-title":"Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations","volume":"11","author":"Lee","year":"2020","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.humimm.2022.02.006_b0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1034\/j.1399-0039.2001.057001015.x","article-title":"Association of soluble HLA-G plasma levels with HLA-G alleles","volume":"57","author":"Rebmann","year":"2001","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.humimm.2022.02.006_b0065","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2019.00058","article-title":"Immune modulation in HLA-G expressing head and neck squamous cell carcinoma in relation to human papilloma virus positivity: A study from northeast India","volume":"9","author":"Sarmah","year":"2019","journal-title":"Front. Oncol."},{"issue":"25","key":"10.1016\/j.humimm.2022.02.006_b0070","doi-asserted-by":"crossref","first-page":"e16067","DOI":"10.1097\/MD.0000000000016067","article-title":"HLA-G +3142 C>G polymorphism and cancer risk: Evidence from a meta-analysis and trial sequential analysis","volume":"98","author":"Jiang","year":"2019","journal-title":"Med. (Baltimore)"},{"issue":"1","key":"10.1016\/j.humimm.2022.02.006_b0075","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4103\/2319-4170.133777","article-title":"Genetic regulation of recurrent spontaneous abortion in humans","volume":"38","author":"Vaiman","year":"2015","journal-title":"Biomed. J."},{"key":"10.1016\/j.humimm.2022.02.006_b0080","series-title":"Reference Module in Biomedical Sciences","article-title":"Early pregnancy termination miscarriage \u2606","author":"Terranova","year":"2017"},{"issue":"2","key":"10.1016\/j.humimm.2022.02.006_b0085","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1034\/j.1399-0039.2002.600202.x","article-title":"HLA-G polymorphisms in couples with recurrent spontaneous abortions","volume":"60","author":"Hviid","year":"2002","journal-title":"Tissue Antigens"},{"issue":"Web Server","key":"10.1016\/j.humimm.2022.02.006_b0090","doi-asserted-by":"crossref","first-page":"W676","DOI":"10.1093\/nar\/gkl253","article-title":"QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequences","volume":"34","author":"Kikin","year":"2006","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.humimm.2022.02.006_b0095","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1093\/bioinformatics\/btx413","article-title":"pqsfinder: an exhaustive and imperfection-tolerant search tool for potential quadruplex-forming sequences in R","volume":"33","author":"Hon","year":"2017","journal-title":"Bioinformatics"},{"issue":"4","key":"10.1016\/j.humimm.2022.02.006_b0100","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1093\/nar\/gkw006","article-title":"Re-evaluation of G-quadruplex propensity with G4Hunter","volume":"44","author":"Bedrat","year":"2016","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.humimm.2022.02.006_b0105","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.1093\/nar\/gkz179","article-title":"Whole genome experimental maps of DNA G-quadruplexes in multiple species","volume":"47","author":"Marsico","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.humimm.2022.02.006_b0110","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2014.00476","article-title":"Insights into HLA-G genetics provided by worldwide haplotype diversity","volume":"5","author":"Castelli","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.humimm.2022.02.006_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.mgene.2019.100624","article-title":"The HLA-G 14 bp allele frequency in different populations: A global meta-analysis","volume":"23","author":"Rodrigues","year":"2020","journal-title":"Meta Gene"},{"issue":"8","key":"10.1016\/j.humimm.2022.02.006_b0120","doi-asserted-by":"crossref","first-page":"3771","DOI":"10.4049\/jimmunol.154.8.3771","article-title":"Human placental HLA-G expression is restricted to differentiated cytotrophoblasts","volume":"154","author":"McMaster","year":"1995","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.humimm.2022.02.006_b0125","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3390\/ijms20030625","article-title":"Increased HLA-G expression in term placenta of women with a history of recurrent miscarriage despite their genetic predisposition to decreased HLA-G levels","volume":"20","author":"Craenmehr","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.humimm.2022.02.006_b0130","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.humimm.2016.01.019","article-title":"sHLA-G1 and HLA-G5 levels are decreased in Tunisian women with multiple abortion","volume":"77","author":"Zidi","year":"2016","journal-title":"Hum. Immunol."},{"issue":"5","key":"10.1016\/j.humimm.2022.02.006_b0135","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.3390\/ijms22052313","article-title":"MicroRNA-mRNA networks in pregnancy complications: A comprehensive downstream analysis of potential biomarkers","volume":"22","author":"Ali","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.humimm.2022.02.006_b0140","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/gene.2009.74","article-title":"The genetic structure of 3\u2019untranslated region of the HLA-G gene: polymorphisms and haplotypes","volume":"11","author":"Castelli","year":"2010","journal-title":"Genes Immun."}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885922000386?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885922000386?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:53:15Z","timestamp":1777528395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885922000386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0198885922000386"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2022.02.006","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A comparative study on regulation of HLA-G expression in bad obstetric history and in head and neck squamous cell carcinoma from Northeast India","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2022.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}