{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:57:36Z","timestamp":1782449856105,"version":"3.54.5"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Immunology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.humimm.2025.111239","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T02:13:01Z","timestamp":1740017581000},"page":"111239","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Alterations in gut microbiota in Rheumatoid arthritis patients with interstitial lung Disease: A Comparative study"],"prefix":"10.1016","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3433-9649","authenticated-orcid":false,"given":"Xue","family":"Zhong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10055","key":"10.1016\/j.humimm.2025.111239_b0005","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"Smolen","year":"2016","journal-title":"Lancet"},{"issue":"160","key":"10.1016\/j.humimm.2025.111239_b0010","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0011-2021","article-title":"Rheumatoid arthritis-interstitial lung disease: manifestations and current concepts in pathogenesis and management","volume":"30","author":"Kadura","year":"2021","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.humimm.2025.111239_b0015","first-page":"1","article-title":"Interstitial lung disease in rheumatic diseases: an update of the 2018 Review","author":"Atzeni","year":"2024","journal-title":"Expert Rev Clin Immunol"},{"issue":"10","key":"10.1016\/j.humimm.2025.111239_b0020","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s11926-016-0614-8","article-title":"The Microbiome: a Revolution in Treatment for Rheumatic Diseases?","volume":"18","author":"Jt","year":"2016","journal-title":"Curr. Rheumatol. Rep."},{"key":"10.1016\/j.humimm.2025.111239_b0025","doi-asserted-by":"crossref","unstructured":"Am K, N S, Kj M.Modulation of immune development and function by intestinal microbiota[J].Trends in immunology,2014, 35 (11): 507-17.","DOI":"10.1016\/j.it.2014.07.010"},{"issue":"4","key":"10.1016\/j.humimm.2025.111239_b0030","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/1756-185X.13802","article-title":"Alteration of the gut microbiota in tumor necrosis factor-\u03b1 antagonist-treated collagen-induced arthritis mice","volume":"23","author":"Wang","year":"2020","journal-title":"Int J Rheum Dis"},{"key":"10.1016\/j.humimm.2025.111239_b0035","doi-asserted-by":"crossref","unstructured":"Pm S, Mr H, N P, et al.The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis[J].Science (New York, N.Y.),2013, 341 (6145): 569-73.","DOI":"10.1126\/science.1241165"},{"key":"10.1016\/j.humimm.2025.111239_b0040","doi-asserted-by":"crossref","unstructured":"Arnett F C, Edworthy S M, Bloch D A, et al.The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis[J].Arthritis Rheum,1988, 31 (3): 315-24.","DOI":"10.1002\/art.1780310302"},{"issue":"9","key":"10.1016\/j.humimm.2025.111239_b0045","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1136\/ard.2010.138461","article-title":"2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"69","author":"Aletaha","year":"2010","journal-title":"Ann Rheum Dis"},{"issue":"Database issue","key":"10.1016\/j.humimm.2025.111239_b0050","first-page":"D590","article-title":"The SILVA ribosomal RNA gene database project: improved data processing and web-based tools","volume":"41","author":"Quast","year":"2013","journal-title":"Nucleic Acids Res"},{"issue":"7","key":"10.1016\/j.humimm.2025.111239_b0055","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nmeth.3869","article-title":"DADA2: High-resolution sample inference from Illumina amplicon data","volume":"13","author":"Callahan","year":"2016","journal-title":"Nat Methods"},{"issue":"8","key":"10.1016\/j.humimm.2025.111239_b0060","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.humimm.2025.111239_b0065","unstructured":"A C.Non-parametric estimation of the classes in a population[J].Scandinavian Journal of Statistics,1984, 11 (4): 265-270."},{"issue":"3","key":"10.1016\/j.humimm.2025.111239_b0070","first-page":"1257","article-title":"The Efficiency of Good's Nonparametric Coverage Estimator","volume":"14","author":"Ww","year":"1986","journal-title":"Annals of Statistics"},{"issue":"51","key":"10.1016\/j.humimm.2025.111239_b0075","doi-asserted-by":"crossref","first-page":"19430","DOI":"10.1073\/pnas.0609333103","article-title":"Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables","volume":"103","author":"Zapala","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.humimm.2025.111239_b0080","doi-asserted-by":"crossref","DOI":"10.3390\/jcm8050693","article-title":"Gut Microbial Composition and Function Are Altered in Patients with Early Rheumatoid Arthritis","volume":"8","author":"Jeong","year":"2019","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.humimm.2025.111239_b0085","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13073-016-0299-7","article-title":"An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis","volume":"8","author":"Chen","year":"2016","journal-title":"Genome Med"},{"key":"10.1016\/j.humimm.2025.111239_b0090","doi-asserted-by":"crossref","unstructured":"Hi C, Jr L, Cc L, et al.An Association of Gut Microbiota with Different Phenotypes in Chinese Patients with Rheumatoid Arthritis[J].Journal of clinical medicine,2019, 8 (11).","DOI":"10.3390\/jcm8111770"},{"key":"10.1016\/j.humimm.2025.111239_b0095","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fcimb.2019.00369","article-title":"Characteristics of Gut Microbiota in Patients With Rheumatoid Arthritis in Shanghai","volume":"9","author":"Sun","year":"2019","journal-title":"China[j].front Cell Infect Microbiol"},{"key":"10.1016\/j.humimm.2025.111239_b0100","first-page":"708","volume":"60","author":"Kim","year":"2021","journal-title":"Influence of Proton Pump Inhibitor or Rebamipide Use on Gut Microbiota of Rheumatoid Arthritis Patients[j].rheumatology"},{"key":"10.1016\/j.humimm.2025.111239_b0105","volume":"12","author":"Mei","year":"2021","journal-title":"Sustained Drug Treatment Alters the Gut Microbiota in Rheumatoid Arthritis[j].front Immunol"},{"key":"10.1016\/j.humimm.2025.111239_b0110","volume":"11","author":"Yu","year":"2021","journal-title":"The Gut Microbiome and Metabolites Are Altered and Interrelated in Patients with Rheumatoid Arthritis[j].front Cell Infect Microbiol"},{"key":"10.1016\/j.humimm.2025.111239_b0115","first-page":"23689","volume":"13","author":"Chen","year":"2021","journal-title":"Analysis of Gut Microbiota and Metabolites in Patients with Rheumatoid Arthritis and Identification of Potential Biomarkers[j].aging"},{"issue":"11","key":"10.1016\/j.humimm.2025.111239_b0120","first-page":"2646","article-title":"Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine[J].Arthritis","volume":"68","author":"Maeda","year":"2016","journal-title":"Rheumatol"},{"key":"10.1016\/j.humimm.2025.111239_b0125","volume":"2","author":"Scher","year":"2013","journal-title":"Expansion of Intestinal Prevotella Copri Correlates with Enhanced Susceptibility to Arthritis[j].elife"},{"issue":"12","key":"10.1016\/j.humimm.2025.111239_b0130","first-page":"2878","article-title":"Suppression of Inflammatory Arthritis by Human Gut-Derived Prevotella histicola in Humanized Mice[J].Arthritis","volume":"68","author":"Marietta","year":"2016","journal-title":"Rheumatol"},{"issue":"1","key":"10.1016\/j.humimm.2025.111239_b0135","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/annrheumdis-2019-215743","article-title":"Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population[J]","volume":"79","author":"Kishikawa","year":"2020","journal-title":"Ann Rheum Dis"}],"container-title":["Human Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885925000102?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0198885925000102?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T17:58:15Z","timestamp":1742234295000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0198885925000102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0198885925000102"],"URL":"https:\/\/doi.org\/10.1016\/j.humimm.2025.111239","relation":{},"ISSN":["0198-8859"],"issn-type":[{"value":"0198-8859","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations in gut microbiota in Rheumatoid arthritis patients with interstitial lung Disease: A Comparative study","name":"articletitle","label":"Article Title"},{"value":"Human Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humimm.2025.111239","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of American Society for Histocompatibility and Immunogenetics.","name":"copyright","label":"Copyright"}],"article-number":"111239"}}