{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T05:17:34Z","timestamp":1761196654907},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.humpath.2005.04.009","type":"journal-article","created":{"date-parts":[[2005,7,2]],"date-time":"2005-07-02T14:48:06Z","timestamp":1120315686000},"page":"686-693","source":"Crossref","is-referenced-by-count":10,"title":["The expression of the 27-kd heat shock protein in keratinization disorders: an immunohistological study"],"prefix":"10.1016","volume":"36","author":[{"given":"Constanze","family":"Jonak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Metze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heiko","family":"Traupe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Happle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arne","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Trautinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2005.04.009_bib1","first-page":"73","article-title":"Heat shock response\u2014pathophysiological implications","volume":"29","author":"Lepp\u00e4","year":"1997","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.humpath.2005.04.009_bib2","doi-asserted-by":"crossref","first-page":"13941","DOI":"10.1016\/S0021-9258(18)92793-6","article-title":"Denaturation of proteins during heat shock. In vitro recovery of solubility and activity of reporter enzymes","volume":"266","author":"Pinto","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1016\/j.humpath.2005.04.009_bib3","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/S0021-9258(18)53882-5","article-title":"Small heat shock proteins are molecular chaperones","volume":"268","author":"Jakob","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.humpath.2005.04.009_bib4","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1093\/jnci\/85.19.1558","article-title":"Biological and clinical implications of heat shock 27000 (hsp27): a review","volume":"85","author":"Ciocca","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.humpath.2005.04.009_bib5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0014-5793(92)81216-9","article-title":"Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins","volume":"313","author":"Stokoe","year":"1992","journal-title":"FEBS Lett"},{"key":"10.1016\/j.humpath.2005.04.009_bib6","first-page":"196","article-title":"Expression of the 27 kD heat shock protein is related to differentiation in human epidermal keratinocytes","volume":"286","author":"Kindas-M\u00fcgge","year":"1994","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.humpath.2005.04.009_bib7","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1365-2133.1995.tb02615.x","article-title":"Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistological study","volume":"133","author":"Trautinger","year":"1995","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1365-2133.2002.04667.x","article-title":"Subcorneal colocalization of the small heat shock protein, hsp27, with keratins and proteins of the cornified cell envelope","volume":"147","author":"Jonak","year":"2002","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib9","doi-asserted-by":"crossref","first-page":"18947","DOI":"10.1074\/jbc.274.27.18947","article-title":"Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress\/tumor necrosis factor alpha by phosphorylation","volume":"274","author":"Rogalla","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.humpath.2005.04.009_bib10","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/brain\/awh033","article-title":"Desmin myopathy","volume":"127","author":"Goldfarb","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.humpath.2005.04.009_bib11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-4362.2003.01308.x","article-title":"Hereditary and acquired ichthyosis vulgaris","volume":"42","author":"Okulicz","year":"2003","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib12","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1399-0004.1984.tb01089.x","article-title":"Autosomal dominant lamellar ichthyosis: a new skin disorder","volume":"26","author":"Traupe","year":"1984","journal-title":"Clin Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib13","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archderm.122.5.529","article-title":"Ichthyosis: genetic heterogeneity, genodermatoses, and genetic counseling","volume":"122","author":"Williams","year":"1986","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib14","first-page":"1146","article-title":"Linkage of autosomal recessive lamellar ichthyosis to chromosome 14q","author":"Russel","year":"1994","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib15","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1093\/hmg\/4.8.1391","article-title":"Autosomal recessive lamellar ichthyosis: identification of a new mutation in transglutaminase 1 and evidence for genetic heterogeneity","volume":"4","author":"Parmentier","year":"1995","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib16","first-page":"555","article-title":"Mapping of a second locus for lamellar ichthyosis to chromosome 2q33-35","volume":"589","author":"Parmentier","year":"1998","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib17","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1086\/302814","article-title":"Two new loci for autosomal recessive ichthyosis on chromosomes 3p21 and 19p12-q12 and evidence for further genetic heterogeneity","volume":"66","author":"Fischer","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib18","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0140-6736(78)90005-3","article-title":"X-linked ichthyosis due to steroid-sulphatase deficiency","volume":"1","author":"Shapiro","year":"1978","journal-title":"Lancet"},{"key":"10.1016\/j.humpath.2005.04.009_bib19","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/BF00282842","article-title":"Further evidence for the assignment of the steroid sulfatase X-linked ichthyosis locus to the telomer of Xp","volume":"58","author":"Muller","year":"1981","journal-title":"Hum Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/75977","article-title":"Mutation in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome","volume":"25","author":"Chavanas","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib21","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1086\/302824","article-title":"Localization of the Netherton syndrome gene to chromosome 5q32, by linkage analysis and homozygosity mapping","volume":"66","author":"Chavanas","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib22","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/ng0196-52","article-title":"Sj\u00f6gren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene","volume":"12","author":"De Laurenzi","year":"1996","journal-title":"Nat Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib23","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1172\/JCI117132","article-title":"Genetic mutation in k1 and k10 genes of patients with epidermolytic hyperkeratosis","volume":"93","author":"Syder","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1016\/j.humpath.2005.04.009_bib24","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/1523-1747.ep12286491","article-title":"A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma","volume":"108","author":"Joh","year":"1997","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib25","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/(SICI)1096-8628(20000214)90:4<339::AID-AJMG15>3.0.CO;2-5","article-title":"Mutations in the NSDHL gene, encoding a 3\u03b2-hydroxysteroid dehydrogenase, cause CHILD syndrome","volume":"90","author":"K\u00f6nig","year":"2000","journal-title":"J Am Med Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib26","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/10350","article-title":"The gene mutated in bare patches and striated mice encodes a novel 3\u03b2-hydroxysteroid dehydrogenase","volume":"22","author":"Liu","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib27","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/(SICI)1096-8628(20000214)90:4<328::AID-AJMG13>3.0.CO;2-F","article-title":"CHILD syndrome caused by deficiency of 3\u03b2-hydroxysteroid-\u03948,\u03947-isomerase","volume":"90","author":"Grange","year":"2000","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib28","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1001\/archderm.129.11.1460","article-title":"Mosaicism in human skin","volume":"129","author":"Happle","year":"1993","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib29","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/10357","article-title":"Mutations in the gene encoding 3\u03b2-hydroxysteroid-\u03948,\u03947-isomerase cause x-linked dominant Conradi-H\u00fcnermann syndrome","volume":"22","author":"Braverman","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib30","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/10350","article-title":"Mutations in a \u03948-\u03947 isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata","volume":"22","author":"Derry","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib31","first-page":"A2","article-title":"27 kD heat shock protein and MAPK signalling regulate the expression of differentiation associated proteins in human keratinocytes","volume":"123","author":"Jonak","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib32","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1046\/j.1523-1747.2003.22258.x","article-title":"Basis for abnormal desquamation and permeability barrier dysfunction in RXLI","volume":"122","author":"Elias","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1046\/j.1365-2133.1999.03098.x","article-title":"X-linked ichthyosis: an update","volume":"141","author":"Hernandez-Martin","year":"1999","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib34","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1046\/j.1523-1747.1998.00386.x","article-title":"Recessive X-linked ichthyosis: role of cholesterol-sulfate accumulation in the barrier abnormality","volume":"111","author":"Zettersten","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.humpath.2005.04.009_bib35","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/hmg\/ddg072","article-title":"Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes","volume":"12","author":"Hermann","year":"2003","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.humpath.2005.04.009_bib36","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.0022-202X.2004.23221.x","article-title":"Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38","volume":"123","author":"Jans","year":"2004","journal-title":"J Invest Dermatol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817705001978?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817705001978?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T23:12:26Z","timestamp":1626131546000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817705001978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0046817705001978"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2005.04.009","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}