{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:52:26Z","timestamp":1761580346473},"reference-count":24,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.humpath.2005.08.006","type":"journal-article","created":{"date-parts":[[2005,10,13]],"date-time":"2005-10-13T13:45:49Z","timestamp":1129211149000},"page":"1120-1126","source":"Crossref","is-referenced-by-count":16,"title":["BMPRIA is a promising marker for evaluating ganglion cells in the enteric nervous system\u2014a pilot study"],"prefix":"10.1016","volume":"36","author":[{"given":"Katherine C.","family":"Brewer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olive","family":"Mwizerva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan M.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2005.08.006_bib1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1055-8586(98)70016-2","article-title":"Hypoganglionosis","volume":"7","author":"Scharli","year":"1998","journal-title":"Semin Pediatr Surg"},{"issue":"47 Suppl 4","key":"10.1016\/j.humpath.2005.08.006_bib2","first-page":"iv81","article-title":"Developmental disorders of the enteric nervous system","author":"Kapur","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.humpath.2005.08.006_bib3","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s10024-001-0142-y","article-title":"Enteric nervous system: development and developmental disturbances\u2014part 1","volume":"5","author":"Newgreen","year":"2002","journal-title":"Pediatr Dev Pathol"},{"key":"10.1016\/j.humpath.2005.08.006_bib4","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1136\/gut.44.6.853","article-title":"Rectal biopsy for diagnosis of intestinal neuronal dysplasia in children: a prospective multicentre study on interobserver variation and clinical outcome","volume":"44","author":"Koletzko","year":"1999","journal-title":"Gut"},{"key":"10.1016\/j.humpath.2005.08.006_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/dvdy.10350","article-title":"HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts","volume":"228","author":"Fu","year":"2003","journal-title":"Dev Dyn"},{"key":"10.1016\/j.humpath.2005.08.006_bib6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00429-003-0371-0","article-title":"Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study","volume":"208","author":"Fu","year":"2004","journal-title":"Anat Embryol (Berl)"},{"key":"10.1016\/j.humpath.2005.08.006_bib7","first-page":"G262","article-title":"Lessons from genetically engineered animal models. II. Disorders of enteric neuronal development: insights from transgenic mice","volume":"277","author":"Gershon","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.humpath.2005.08.006_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.mod.2005.03.003","article-title":"BMP signaling is necessary for neural crest cell migration and ganglion formation in the enteric nervous system","volume":"122","author":"Goldstein","year":"2005","journal-title":"Mech Dev"},{"key":"10.1016\/j.humpath.2005.08.006_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/dvdy.20554","article-title":"BMP signaling pathway plays multiple roles during gastrointestinal tract development","author":"de Santa Barbara","year":"2005","journal-title":"Dev Dyn"},{"key":"10.1016\/j.humpath.2005.08.006_bib10","doi-asserted-by":"crossref","first-page":"4749","DOI":"10.1242\/dev.126.21.4749","article-title":"Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube","volume":"126","author":"Sela-Donenfeld","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.humpath.2005.08.006_bib11","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1006\/dbio.2000.9684","article-title":"Expression and regulation of type I BMP receptors during early avian sympathetic ganglion development","volume":"221","author":"McPherson","year":"2000","journal-title":"Dev Biol"},{"key":"10.1016\/j.humpath.2005.08.006_bib12","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)81112-5","article-title":"Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members","volume":"85","author":"Shah","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.humpath.2005.08.006_bib13","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0896-6273(03)00727-X","article-title":"Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells","volume":"40","author":"Kruger","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.humpath.2005.08.006_bib14","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1242\/dev.127.9.1971","article-title":"The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium","volume":"127","author":"Sukegawa","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.humpath.2005.08.006_bib15","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0960-9822(06)00191-6","article-title":"MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cells","volume":"7","author":"Lo","year":"1997","journal-title":"Curr Biol"},{"key":"10.1016\/j.humpath.2005.08.006_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.2000.9876","article-title":"Postmigratory enteric and sympathetic neural precursors share common, developmentally regulated, responses to BMP2","volume":"227","author":"Pisano","year":"2000","journal-title":"Dev Biol"},{"key":"10.1016\/j.humpath.2005.08.006_bib17","doi-asserted-by":"crossref","first-page":"4266","DOI":"10.1523\/JNEUROSCI.3688-03.2004","article-title":"Bone morphogenetic protein-2 and -4 limit the number of enteric neurons but promote development of a TrkC-expressing neurotrophin-3\u2013dependent subset","volume":"24","author":"Chalazonitis","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.humpath.2005.08.006_bib18","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1365-2982.2004.00538.x","article-title":"Human enteric neuropathies: morphology and molecular pathology","volume":"16","author":"De Giorgio","year":"2004","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.humpath.2005.08.006_bib19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/path.1711680110","article-title":"Evaluation of PGP9.5 in the diagnosis of Hirschsprung's disease","volume":"168","author":"Sams","year":"1992","journal-title":"J Pathol"},{"key":"10.1016\/j.humpath.2005.08.006_bib20","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1055\/s-2008-1066117","article-title":"Immunohistochemistry of markers of the enteric nervous system in whole-mount preparations of the human colon","volume":"4","author":"Krammer","year":"1994","journal-title":"Eur J Pediatr Surg"},{"key":"10.1016\/j.humpath.2005.08.006_bib21","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/0022-3468(93)90519-Q","article-title":"Immunocytochemistry for neuronal markers shows deficiencies in conventional histology in the treatment of Hirschsprung's disease","volume":"28","author":"Romanska","year":"1993","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.humpath.2005.08.006_bib22","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1055\/s-2002-36856","article-title":"Suitability of selected markers for identification of elements of the intestinal nervous system (INS)","volume":"12","author":"Dzienis-Koronkiewicz","year":"2002","journal-title":"Eur J Pediatr Surg"},{"key":"10.1016\/j.humpath.2005.08.006_bib23","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/(SICI)1097-0185(199807)251:3<360::AID-AR12>3.0.CO;2-M","article-title":"A neuronal subpopulation in the mammalian enteric nervous system expresses TrkA and TrkC neurotrophin receptor\u2013like proteins","volume":"251","author":"Esteban","year":"1998","journal-title":"Anat Rec"},{"key":"10.1016\/j.humpath.2005.08.006_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.10448","article-title":"Acquisition of neuronal and glial markers by neural crest\u2013derived cells in the mouse intestine","volume":"456","author":"Young","year":"2003","journal-title":"J Comp Neurol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817705004053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817705004053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,18]],"date-time":"2021-07-18T14:56:29Z","timestamp":1626620189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817705004053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0046817705004053"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2005.08.006","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}