{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T14:45:49Z","timestamp":1785681949931,"version":"3.56.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.humpath.2006.01.009","type":"journal-article","created":{"date-parts":[[2006,6,12]],"date-time":"2006-06-12T16:47:53Z","timestamp":1150130873000},"page":"586-592","source":"Crossref","is-referenced-by-count":36,"title":["STAT 5a expression in the breast is maintained in secretory carcinoma, in contrast to other histologic types"],"prefix":"10.1016","volume":"37","author":[{"given":"Brian L.","family":"Strauss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary L.","family":"Bratthauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fattaneh A.","family":"Tavassoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2006.01.009_bib1","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/S0002-9440(10)63403-7","article-title":"Roles and regulation of STAT family transcription factors in human breast cancer","volume":"165","author":"Clevenger","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.humpath.2006.01.009_bib2","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1210\/me.16.5.1108","article-title":"Basal activation of transcription factor signal transducer and activator of transcription (STAT 5) in nonpregnant mouse and human breast epithelium","volume":"16","author":"Nevalainen","year":"2002","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.humpath.2006.01.009_bib3","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1083\/jcb.200107065","article-title":"Signal transducer and activator of transcription (STAT) 5 controls the proliferation and differentiation of mammary alveolar epithelium","volume":"155","author":"Miyoshi","year":"2001","journal-title":"J Cell Biol"},{"key":"10.1016\/j.humpath.2006.01.009_bib4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00428-005-0056-6","article-title":"STAT 5a expression in various lesions of the breast","volume":"448","author":"Bratthauer","year":"2006","journal-title":"Virchows Archiv"},{"key":"10.1016\/j.humpath.2006.01.009_bib5","series-title":"World Health Organization classification of tumours: pathology and genetics of tumours of the breast and female genital organs","first-page":"19","year":"2003"},{"key":"10.1016\/j.humpath.2006.01.009_bib6","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0167-4889(99)00129-9","article-title":"Regulation of signal transducers and activators of transcription (STATs) by effectors of adipogenesis: coordinate regulation of STATs 1, 5a, and 5b with peroxisome proliferator\u2013activated receptor-gamma and C\/AAAT enhancer binding protein-alpha","volume":"1452","author":"Stewart","year":"1999","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.humpath.2006.01.009_bib7","series-title":"Immunocytochemical methods and protocols","first-page":"203","article-title":"The avidin-biotin complex (ABC) method and other avidin-biotin binding methods","volume":"115","author":"Bratthauer","year":"1999"},{"key":"10.1016\/j.humpath.2006.01.009_bib8","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/S0046-8177(03)00423-4","article-title":"Secretory carcinoma of the breast: a distinct variant of invasive ductal carcinoma assessed by comparative genomic hybridization and immunohistochemistry","volume":"34","author":"Diallo","year":"2003","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2006.01.009_bib9","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1007\/s000180050395","article-title":"Physiological significance of STAT proteins: investigations through gene disruption in vivo","volume":"55","author":"Levy","year":"1999","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.humpath.2006.01.009_bib10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1006\/dbio.2000.9961","article-title":"Prolactin, growth hormone, and epidermal growth factor activate STAT 5a in different compartments of mammary tissue and exert different and overlapping developmental effects","volume":"229","author":"Gallego","year":"2001","journal-title":"Dev Biol"},{"key":"10.1016\/j.humpath.2006.01.009_bib11","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1002\/ijc.11619","article-title":"Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers","volume":"108","author":"Cotarla","year":"2004","journal-title":"Int J Cancer"},{"key":"10.1016\/j.humpath.2006.01.009_bib12","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10549-004-0805-2","article-title":"Possible role of Stat5a in rat mammary gland carcinogenesis","volume":"88","author":"Shan","year":"2004","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2006.01.009_bib13","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1200\/JCO.2004.11.046","article-title":"Signal transducer and activator of transcription-5 activation and breast cancer prognosis","volume":"22","author":"Nevalainen","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2006.01.009_bib14","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1535-6108(02)00180-0","article-title":"Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma","volume":"2","author":"Tognon","year":"2002","journal-title":"Cancer Cell"},{"key":"10.1016\/j.humpath.2006.01.009_bib15","first-page":"8909","article-title":"The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1\/2 and PI3-kinase\u2013Akt signaling for fibroblast transformation","volume":"61","author":"Tognon","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.humpath.2006.01.009_bib16","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1309\/3H24-E7T7-V37G-AKKQ","article-title":"Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues","volume":"115","author":"Sheng","year":"2001","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2006.01.009_bib17","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1074\/jbc.M307388200","article-title":"A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation","volume":"279","author":"Lannon","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.humpath.2006.01.009_bib18","doi-asserted-by":"crossref","first-page":"5684","DOI":"10.1038\/sj.onc.1205669","article-title":"ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation","volume":"21","author":"Morrison","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.humpath.2006.01.009_bib19","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1182\/blood.V90.7.2535","article-title":"Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia","volume":"90","author":"Peeters","year":"1997","journal-title":"Blood"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817706000177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817706000177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T12:04:11Z","timestamp":1586952251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817706000177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0046817706000177"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2006.01.009","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}