{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:56:10Z","timestamp":1791053770480,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.humpath.2006.09.012","type":"journal-article","created":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T12:58:09Z","timestamp":1169557089000},"page":"462-467","source":"Crossref","is-referenced-by-count":37,"title":["Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma."],"prefix":"10.1016","volume":"38","author":[{"given":"Agnieszka","family":"Witkiewicz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puthiyaveettil","family":"Raghunath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Wasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline M.","family":"Junkins-Hopkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Odum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz A.","family":"Wasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2006.09.012_bib1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1468-3083.2004.00937.x","article-title":"Clinicopathological spectrum of mycosis fungoides","volume":"18","author":"Kazakov","year":"2004","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.humpath.2006.09.012_bib2","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1001\/archderm.139.7.857","article-title":"Long-term outcome of 525 patients with mycosis fungoides and Sezary syndrome: clinical prognostic factors and risk for disease progression","volume":"139","author":"Kim","year":"2003","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.humpath.2006.09.012_bib3","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.2105\/AJPH.89.8.1240","article-title":"Twenty year trends in the reported incidence of mycosis fungoides and associated mortality","volume":"89","author":"Weinstock","year":"1999","journal-title":"Am J Public Health"},{"key":"10.1016\/j.humpath.2006.09.012_bib4","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0002-9440(10)64629-9","article-title":"Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter","volume":"57","author":"Zhang","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.humpath.2006.09.012_bib5","doi-asserted-by":"crossref","first-page":"6948","DOI":"10.1073\/pnas.0501959102","article-title":"STAT3- and DNA methyltransferase 1\u2013mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes","volume":"102","author":"Zhang","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humpath.2006.09.012_bib6","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1182\/blood-2005-08-007377","article-title":"STAT3 induces transcription of the DNA methyltransferase 1 (DNMT1) gene in malignant T lymphocytes","volume":"108","author":"Zhang","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2006.09.012_bib7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/archderm.117.7.408","article-title":"Attempts to enhance light microscopic diagnosis of cutaneous T-cell lymphoma (mycosis fungoides)","volume":"117","author":"Lefeber","year":"1981","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.humpath.2006.09.012_bib8","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.1182\/blood-2004-09-3502","article-title":"WHO-EORTC classification for cutaneous lymphomas","volume":"105","author":"Willemze","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2006.09.012_bib9","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1242\/jcs.00963","article-title":"The JAK\/STAT signaling pathway","volume":"117","author":"Rawlings","year":"2004","journal-title":"J Cell Sci"},{"key":"10.1016\/j.humpath.2006.09.012_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/nrc1275","article-title":"The STATs of cancer\u2014new molecular targets come of age","volume":"4","author":"Yu","year":"2004","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.humpath.2006.09.012_bib11","doi-asserted-by":"crossref","first-page":"6764","DOI":"10.1073\/pnas.94.13.6764","article-title":"Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines","volume":"94","author":"Nielsen","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.humpath.2006.09.012_bib12","doi-asserted-by":"crossref","first-page":"5361","DOI":"10.1038\/sj.onc.1205609","article-title":"DNA methylation and chromatin\u2014unraveling the tangled web","volume":"21","author":"Robertson","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.humpath.2006.09.012_bib13","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1365-2141.2005.05516.x","article-title":"SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients: a new prognostic factor","volume":"129","author":"Mena-Duran","year":"2005","journal-title":"Br J Haematol"},{"key":"10.1016\/j.humpath.2006.09.012_bib14","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1038\/sj.leu.2403385","article-title":"In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3","volume":"18","author":"Sommer","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2006.09.012_bib15","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1053\/j.seminoncol.2005.07.024","article-title":"Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents","volume":"32","author":"Claus","year":"2005","journal-title":"Semin Oncol"},{"key":"10.1016\/j.humpath.2006.09.012_bib16","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1158\/1535-7163.MCT-05-0302","article-title":"Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer","volume":"5","author":"Jing","year":"2006","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.humpath.2006.09.012_bib17","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1158\/1541-7786.62.2.1","article-title":"Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation","volume":"2","author":"Weisenberger","year":"2004","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.humpath.2006.09.012_bib18","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1093\/annonc\/mdg216","article-title":"A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly","volume":"14","author":"Stewart","year":"2003","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2006.09.012_bib19","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1158\/1535-7163.1533.3.12","article-title":"Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity","volume":"3","author":"Turkson","year":"2004","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.humpath.2006.09.012_bib20","doi-asserted-by":"crossref","first-page":"6385","DOI":"10.1128\/JVI.77.11.6385-6393.2003","article-title":"STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling","volume":"77","author":"Ulane","year":"2003","journal-title":"J Virol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817706005752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817706005752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T13:47:36Z","timestamp":1683726456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817706005752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0046817706005752"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2006.09.012","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}