{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T14:46:03Z","timestamp":1785681963047,"version":"3.56.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.humpath.2007.06.018","type":"journal-article","created":{"date-parts":[[2008,1,16]],"date-time":"2008-01-16T11:31:41Z","timestamp":1200483101000},"page":"175-183","source":"Crossref","is-referenced-by-count":44,"title":["D2-40 expression by breast myoepithelium: potential pitfalls in distinguishing intralymphatic carcinoma from in situ carcinoma"],"prefix":"10.1016","volume":"39","author":[{"given":"Joseph T.","family":"Rabban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunn-Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2007.06.018_bib1","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1002\/1097-0142(19920315)69:6<1396::AID-CNCR2820690615>3.0.CO;2-I","article-title":"Peritumoral lymphatic invasion in patients with node-negative mammary duct carcinoma","volume":"69","author":"Clemente","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2007.06.018_bib2","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/01.sla.0000133355.48672.22","article-title":"Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer","volume":"240","author":"Schoppmann","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.humpath.2007.06.018_bib3","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1023\/A:1010668616265","article-title":"Angiogenesis and blood vessel invasion as prognostic indicators for node-negative breast cancer","volume":"65","author":"Kato","year":"2001","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2007.06.018_bib4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0959-8049(97)00344-4","article-title":"Obvious peritumoral emboli: an elusive prognostic factor reappraised. Multivariate analysis of 1320 node-negative breast cancers","volume":"34","author":"de Mascarel","year":"1998","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.humpath.2007.06.018_bib5","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.humpath.2003.05.004","article-title":"Histological characteristics of tumor in vessels and lymph nodes are significant predictors of progression of invasive ductal carcinoma of the breast: a prospective study","volume":"35","author":"Hasebe","year":"2004","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib6","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2559.1994.tb01269.x","article-title":"Pathological prognostic factors in breast cancer: III. Vascular invasion: relationship with recurrence and survival in a large study with long-term follow-up","volume":"24","author":"Pinder","year":"1994","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2007.06.018_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ejca.2005.10.021","article-title":"Prognostic value of lymphovascular invasion in women with lymph node negative invasive breast carcinoma","volume":"42","author":"Lee","year":"2006","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.humpath.2007.06.018_bib8","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1002\/1097-0142(19951115)76:10<1772::AID-CNCR2820761014>3.0.CO;2-O","article-title":"The prognostic value of lymphatic and blood vessel invasion in operable breast cancer","volume":"76","author":"Lauria","year":"1995","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2007.06.018_bib9","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1093\/annonc\/mdi326","article-title":"Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005","volume":"16","author":"Goldhirsch","year":"2005","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2007.06.018_bib10","doi-asserted-by":"crossref","first-page":"4958","DOI":"10.1200\/JCO.2004.02.122","article-title":"Randomized parallel study of doxorubicin plus paclitaxel and doxorubicin plus cyclophosphamide as neoadjuvant treatment of patients with breast cancer","volume":"22","author":"Dieras","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2007.06.018_bib11","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0046-8177(82)80121-4","article-title":"Interobserver variation in the identification of breast carcinoma in intramammary lymphatics","volume":"13","author":"Gilchrist","year":"1982","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib12","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1002\/1097-0142(19900901)66:5<972::AID-CNCR2820660528>3.0.CO;2-O","article-title":"Topographic criteria in the diagnosis of tumor emboli in intramammary lymphatics","volume":"66","author":"Orbo","year":"1990","journal-title":"Cancer"},{"issue":"Pt 2","key":"10.1016\/j.humpath.2007.06.018_bib13","first-page":"215","article-title":"Tumor emboli in intramammary lymphatics in breast carcinoma: pathologic criteria for diagnosis and clinical significance","volume":"18","author":"Rosen","year":"1983","journal-title":"Pathol Annu"},{"key":"10.1016\/j.humpath.2007.06.018_bib14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/01.pas.0000213316.59176.9b","article-title":"Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinoma","volume":"31","author":"Acs","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib15","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1097\/01.pas.0000174269.99459.9d","article-title":"Lymphangiogenesis does not occur in breast cancer","volume":"29","author":"Agarwal","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib16","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/modpathol.3800728","article-title":"Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer","volume":"20","author":"Arnaout-Alkarain","year":"2007","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib17","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1097\/01.LAB.0000028824.03032.AB","article-title":"A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors","volume":"82","author":"Kahn","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.humpath.2007.06.018_bib18","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1038\/sj.bjc.6603152","article-title":"Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study","volume":"94","author":"Van den Eynden","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1016\/j.humpath.2007.06.018_bib19","doi-asserted-by":"crossref","first-page":"7637","DOI":"10.1158\/1078-0432.CCR-05-1142","article-title":"Tumor lymphangiogenesis in inflammatory breast carcinoma: a histomorphometric study","volume":"11","author":"Van der Auwera","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.humpath.2007.06.018_bib20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.humpath.2006.07.017","article-title":"Accurate assessment of lymph vessel tumor emboli in invasive ductal carcinoma of the breast according to tumor areas, and their prognostic significance","volume":"38","author":"Yamauchi","year":"2006","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib21","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1097\/01.LAB.0000028824.03032.AB","article-title":"A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors","volume":"82","author":"Kahn","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.humpath.2007.06.018_bib22","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0002-9440(10)62311-5","article-title":"Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors","volume":"166","author":"Schacht","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1016\/j.humpath.2007.06.018_bib23","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/dvdy.10163","article-title":"Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate","volume":"225","author":"Hong","year":"2002","journal-title":"Dev Dyn"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817707003620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817707003620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T20:27:45Z","timestamp":1557174465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817707003620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0046817707003620"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2007.06.018","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}