{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T07:30:12Z","timestamp":1675755012237},"reference-count":19,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.humpath.2009.11.004","type":"journal-article","created":{"date-parts":[[2010,2,15]],"date-time":"2010-02-15T06:38:52Z","timestamp":1266215932000},"page":"758-762","source":"Crossref","is-referenced-by-count":4,"title":["JAK2 V617F mutation is uncommon in patients with the 3q21q26 syndrome"],"prefix":"10.1016","volume":"41","author":[{"given":"Pei","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajyalakshmi","family":"Luthra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto H.","family":"Nussenzveig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Jeffrey","family":"Medeiros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2009.11.004_bib1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0165-4608(92)90208-P","article-title":"Three new cases of chromosome 3 rearrangement in bands q21 and q26 with abnormal thrombopoiesis bring further evidence to the existence of a 3q21q26 syndrome","volume":"59","author":"Jotterand Bellomo","year":"1992","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.humpath.2009.11.004_bib2","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1182\/blood-2006-03-008227","article-title":"The JAK2-V617F mutation and essential thrombocythemia features in a subset of patients with refractory anemia with ring sideroblasts (RARS)","volume":"108","author":"Boissinot","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2009.11.004_bib3","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1182\/asheducation-2008.1.52","article-title":"The role of JAK2 mutations in RARS and other MDS","volume":"2008","author":"Hellstrom-Lindberg","year":"2008","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"10.1016\/j.humpath.2009.11.004_bib4","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/sj.leu.2404215","article-title":"The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow","volume":"20","author":"Ingram","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2009.11.004_bib5","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1038\/leu.2008.229","article-title":"JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science","volume":"22","author":"Kilpivaara","year":"2008","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2009.11.004_bib6","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1365-2141.2008.07447.x","article-title":"Van-den Berghe's 5q\u2212 syndrome in 2008","volume":"144","author":"Mohamedali","year":"2009","journal-title":"Br J Haematol"},{"key":"10.1016\/j.humpath.2009.11.004_bib7","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3324\/haematol.11581","article-title":"JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis","volume":"93","author":"Schmitt-Graeff","year":"2008","journal-title":"Haematologica"},{"key":"10.1016\/j.humpath.2009.11.004_bib8","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1182\/blood-2005-03-1183","article-title":"The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both \u201catypical\u201d myeloproliferative disorders and myelodysplastic syndromes","volume":"106","author":"Steensma","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2009.11.004_bib9","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1182\/blood-2006-02-005751","article-title":"Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F mutation","volume":"108","author":"Szpurka","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2009.11.004_bib10","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/sj.leu.2405049","article-title":"The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2(V617F)","volume":"22","author":"Guerini","year":"2008","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2009.11.004_bib11","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1309\/H8JH6L094B9U3HGT","article-title":"t(8;21)(q22;q22) in blast phase of chronic myelogenous leukemia","volume":"121","author":"Yin","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2009.11.004_bib12","series-title":"International system for human cytogenetic nomenclature","author":"ISCN","year":"2005"},{"key":"10.1016\/j.humpath.2009.11.004_bib13","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/modpathol.3800327","article-title":"Combined laser capture microdissection and serial analysis of gene expression from human tissue samples","volume":"18","author":"Cho-Vega","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2009.11.004_bib14","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/modpathol.2008.92","article-title":"Acute myeloid leukemia harboring t(8;21)(q22;q22): a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations","volume":"21","author":"Lin","year":"2008","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2009.11.004_bib15","first-page":"1221","article-title":"Association of 3q21q26 syndrome with different RPN1\/EVI1 fusion transcripts","volume":"88","author":"Martinelli","year":"2003","journal-title":"Haematologica"},{"key":"10.1016\/j.humpath.2009.11.004_bib16","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1365-2141.1995.tb05316.x","article-title":"Thrombopoietin is not responsible for the thrombocytosis observed in patients with acute myeloid leukemias and the 3q21q26 syndrome","volume":"91","author":"Bouscary","year":"1995","journal-title":"Br J Haematol"},{"key":"10.1016\/j.humpath.2009.11.004_bib17","first-page":"1328","article-title":"The human thrombopoietin gene is located on chromosome 3q26.33-q27, but is not transcriptionally activated in leukemia cells with 3q21 and 3q26 abnormalities (3q21q26 syndrome)","volume":"9","author":"Suzukawa","year":"1995","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2009.11.004_bib18","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1182\/blood-2005-03-1320","article-title":"Widespread occurrence of the JAK2V617F mutation in chronic myeloproliferative disorders","volume":"106","author":"Jones","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2009.11.004_bib19","doi-asserted-by":"crossref","first-page":"58","DOI":"10.2353\/jmoldx.2008.070061","article-title":"Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non\u2013mast [corrected] cell lineage disorder carrying the activating point mutations KITD816V and JAK2V617F","volume":"10","author":"Sotlar","year":"2008","journal-title":"J Mol Diagn"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817709004079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817709004079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T01:22:50Z","timestamp":1544664170000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817709004079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0046817709004079"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2009.11.004","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}