{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:30:16Z","timestamp":1789396216107,"version":"build-2803163510"},"reference-count":21,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.humpath.2009.12.010","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T08:37:53Z","timestamp":1269506273000},"page":"1079-1086","source":"Crossref","is-referenced-by-count":28,"title":["Nucleophosmin, p53, and Ki-67 expression patterns on an oral squamous cell carcinoma tissue microarray"],"prefix":"10.1016","volume":"41","author":[{"given":"Cl\u00e1udia Malheiros","family":"Coutinho-Camillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Vanessa","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas Nobuko","family":"Nishimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Augusto","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2009.12.010_bib1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.tripleo.2005.07.038","article-title":"Oral squamous cell carcinoma: review of prognostic and predictive factors","volume":"102","author":"Massano","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.humpath.2009.12.010_bib2","series-title":"Current surgical diagnosis and treatment","first-page":"282","article-title":"Head and neck tumors","author":"Beenken","year":"2003"},{"key":"10.1016\/j.humpath.2009.12.010_bib3","series-title":"Principles of surgery","first-page":"601","article-title":"Tumors of the head and neck","author":"Coleman","year":"1999"},{"key":"10.1016\/j.humpath.2009.12.010_bib4","series-title":"The World Health Organization Report 2003","first-page":"6","author":"World Health Organization","year":"2003"},{"key":"10.1016\/j.humpath.2009.12.010_bib5","series-title":"In: Estimativa 2008: Incid\u00eancia de C\u00e2ncer no Brasil.","article-title":"Minist\u00e9rio da Sa\u00fade. Secretaria de Aten\u00e7\u00e3o \u00e0 Sa\u00fade. Insituto Nacional do C\u00e2ncer. Coordena\u00e7\u00e3o de Preven\u00e7\u00e3o e Vigil\u00e2ncia. Estimativa 2008: Incid\u00eancia de C\u00e2ncer no Brasil.","year":"2008"},{"key":"10.1016\/j.humpath.2009.12.010_bib6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/0019-509X.25886","article-title":"Oral squamous cell carcinoma: etiology, pathogenesis and prognostic value of genomic alterations","volume":"43","author":"Mehrotra","year":"2006","journal-title":"Indian J Cancer"},{"key":"10.1016\/j.humpath.2009.12.010_bib7","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.oraloncology.2005.05.008","article-title":"Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma","volume":"42","author":"Woolgar","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.humpath.2009.12.010_bib8","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1093\/annonc\/mdh299","article-title":"Prognostic relevance of cell proliferation in head and neck tumors","volume":"15","author":"Pich","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2009.12.010_bib9","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/154411130201300106","article-title":"Cell cycle dysregulation in oral cancer","volume":"13","author":"Todd","year":"2002","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.humpath.2009.12.010_bib10","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1034\/j.1600-0714.2000.290901.x","article-title":"The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck","volume":"29","author":"Nylander","year":"2000","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.humpath.2009.12.010_bib11","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/sj.bjc.6603574","article-title":"Increased expression of nucleophosmin\/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters","volume":"96","author":"Yun","year":"2007","journal-title":"Br J Cancer"},{"key":"10.1016\/j.humpath.2009.12.010_bib12","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nrc1885","article-title":"Nucleophosmin and cancer","volume":"6","author":"Grisendi","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.humpath.2009.12.010_bib13","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.cdp.2006.10.008","article-title":"Nucleophosmin and human cancer","volume":"30","author":"Lim","year":"2006","journal-title":"Cancer Detect Prev"},{"key":"10.1016\/j.humpath.2009.12.010_bib14","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.1128\/MCB.01969-08","article-title":"Acetylated NPM1 localizes in the nucleoplasm and regulates transcriptional activation of genes implicated in oral cancer manifestation","volume":"29","author":"Shandilya","year":"2009","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.humpath.2009.12.010_bib15","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1038\/leu.2008.68","article-title":"Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations","volume":"22","author":"Cilloni","year":"2008","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2009.12.010_bib16","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1182\/blood-2006-03-007013","article-title":"Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia","volume":"108","author":"Falini","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2009.12.010_bib17","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1183\/09031936.00008408","article-title":"The role of NPM, p14arf and MDM2 in precursors of bronchial squamous cell carcinoma","volume":"32","author":"Mascaux","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.humpath.2009.12.010_bib18","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1056\/NEJMoa041974","article-title":"Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype","volume":"352","author":"Falini","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humpath.2009.12.010_bib19","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1745-7254.2008.00747.x","article-title":"Association of nucleophosmin\/B23 with bladder cancer recurrence based on immunohistochemical assessment in clinical samples","volume":"29","author":"Tsui","year":"2008","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.humpath.2009.12.010_bib20","first-page":"533","article-title":"Nucleophosmin regulates the stability and transcriptional activity of p53","volume":"529","author":"Colombo","year":"2002","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.humpath.2009.12.010_bib21","first-page":"285","article-title":"Oncogenic role of nucleophosmin\/B23","volume":"30","author":"Yung","year":"2007","journal-title":"Chang Gung Med J"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817710000158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817710000158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T08:56:23Z","timestamp":1544604983000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817710000158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0046817710000158"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2009.12.010","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}