{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:50:38Z","timestamp":1781765438627,"version":"3.54.5"},"reference-count":22,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.humpath.2011.08.007","type":"journal-article","created":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T00:14:36Z","timestamp":1323648876000},"page":"1003-1011","source":"Crossref","is-referenced-by-count":49,"title":["Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy"],"prefix":"10.1016","volume":"43","author":[{"given":"Ashley","family":"Cimino-Mathews","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Hicks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Illei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc K.","family":"Halushka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Fetting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo M.","family":"De Marzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben Ho","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Argani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2011.08.007_bb0005","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/cncr.11532","article-title":"Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies","volume":"98","author":"Moinfar","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2011.08.007_bb0010","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/annonc\/mdp510","article-title":"Expression of androgen receptors in primary breast cancer","volume":"21","author":"Park","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0015","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/modpathol.2009.159","article-title":"Androgen receptor in breast cancer: expression in estrogen receptor\u2013positive tumors and in estrogen receptor\u2013negative tumors with apocrine differentiation","volume":"23","author":"Neimeier","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0020","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1309\/42F00D0DJD0J5EDT","article-title":"Androgen receptor expression in estrogen receptor\u2013negative breast cancer. Immunohistochemical, clinical, and prognostic associations","volume":"120","author":"Agoff","year":"2003","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0025","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.humpath.2007.07.007","article-title":"Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast","volume":"39","author":"Hanley","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0030","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00428-010-0964-y","article-title":"Androgen receptor is frequently expressed in HER2-positive, ER\/PR-negative breast cancers","volume":"457","author":"Micello","year":"2010","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2011.08.007_bb0035","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/PPO.0b013e3181ce4ae1","article-title":"Triple-negative breast cancer: role of the androgen receptor","volume":"16","author":"Gucalp","year":"2010","journal-title":"Cancer J"},{"key":"10.1016\/j.humpath.2011.08.007_bb0040","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2217\/14796694.4.1.15","article-title":"Androgen receptor as a target for the treatment of hormone receptor\u2013negative breast cancer: an unchartered territory","volume":"4","author":"Nahleh","year":"2008","journal-title":"Future Oncol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0045","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s00428-006-0213-6","article-title":"Evaluation of the prognostic significance of androgen receptor expression in metastatic breast cancer","volume":"449","author":"Schippinger","year":"2006","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2011.08.007_bb0050","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1158\/1078-0432.CCR-07-4082","article-title":"Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases","volume":"14","author":"Wu","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.humpath.2011.08.007_bb0055","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/PAS.0b013e31817f9790","article-title":"Most basal-like breast carcinomas demonstrate the same Rb-\/p16+ immunophenotype as the HPV-related poorly differentiated squamous cell carcinomas which they resemble morphologically","volume":"33","author":"Subhawong","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0060","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/modpathol.2010.93","article-title":"Heterogeneity of Bcl-2 expression in metastatic breast carcinoma","volume":"23","author":"Subhawong","year":"2010","journal-title":"Mod Pathol"},{"issue":"12 Suppl","key":"10.1016\/j.humpath.2011.08.007_bb0065","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1002\/1097-0142(19801215)46:12+<2838::AID-CNCR2820461421>3.0.CO;2-A","article-title":"Estrogen and progesterone receptors in the prediction of response of breast cancer to endocrine therapy","volume":"46","author":"Manni","year":"1980","journal-title":"Cancer"},{"issue":"12 Suppl","key":"10.1016\/j.humpath.2011.08.007_bb0070","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1002\/1097-0142(19801215)46:12+<2884::AID-CNCR2820461429>3.0.CO;2-U","article-title":"The value of estrogen and progesterone receptors in the treatment of breast cancer","volume":"46","author":"Osborne","year":"1980","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2011.08.007_bb0075","doi-asserted-by":"crossref","first-page":"8019","DOI":"10.1158\/1078-0432.CCR-08-0974","article-title":"Emerging biomarkers and new understanding of traditional markers in personalized therapy for breast cancer","volume":"14","author":"Dowsett","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.humpath.2011.08.007_bb0080","first-page":"97545","article-title":"Survival of patients with metastatic breast carcinoma: importance of prognostic markers of the primary tumor","author":"Chang","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2011.08.007_bb0085","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1053\/hupa.2001.24327","article-title":"Apocrine ductal carcinoma in situ of the breast: histologic classification and expression of biologic markers","volume":"32","author":"Leal","year":"2001","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0090","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1007\/s00428-005-0003-6","article-title":"Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma","volume":"447","author":"Riva","year":"2005","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2011.08.007_bb0095","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.urology.2009.12.057","article-title":"Salvage therapy with bicalutamide 150 mg in nonmetastatic castration-resistant prostate cancer","volume":"76","author":"Lodde","year":"2010","journal-title":"Urology"},{"issue":"Suppl 2","key":"10.1016\/j.humpath.2011.08.007_bb0100","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1038\/modpathol.2008.34","article-title":"Current issues in ER and HER2 testing by IHC in breast cancer","volume":"21","author":"Gown","year":"2008","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2011.08.007_bb0105","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s10549-009-0671-z","article-title":"Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases","volume":"123","author":"Cimino","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2011.08.007_bb0110","first-page":"73A","article-title":"MYC gene amplification in breast cancer metastases relative to matched primary tumors","volume":"23","author":"Singhi","year":"2010","journal-title":"Mod Pathol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817711003431?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817711003431?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T23:26:45Z","timestamp":1543361205000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817711003431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0046817711003431"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2011.08.007","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}