{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:02:45Z","timestamp":1792098165826,"version":"4.4.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.humpath.2013.05.007","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T06:30:29Z","timestamp":1373437829000},"page":"2247-2255","source":"Crossref","is-referenced-by-count":43,"title":["PAX8 expression in sporadic hemangioblastoma of the kidney supports a primary renal cell lineage: implications for differential diagnosis"],"prefix":"10.1016","volume":"44","author":[{"given":"Ming","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean R.","family":"Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenping","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changshui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangjiang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2013.05.007_bb0005","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1365-2613.2007.00535.x","article-title":"Central nervous system capillary haemangioblastoma: the pathologist's viewpoint","volume":"88","author":"Hussein","year":"2007","journal-title":"Int J Exp Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0010","series-title":"WHO Classification of Tumours of the Central Nervous System","first-page":"184","article-title":"Haemangioblastoma","author":"Aldape","year":"2007"},{"key":"10.1016\/j.humpath.2013.05.007_bb0015","series-title":"WHO Classification of Tumours of the Central Nervous System","first-page":"215","article-title":"von Hippel-Lindau disease and haemangioblastoma","author":"Plate","year":"2007"},{"key":"10.1016\/j.humpath.2013.05.007_bb0020","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1097\/PAS.0b013e3180457bfc","article-title":"Extraneural hemangioblastoma: a report of 5 cases","volume":"31","author":"Nonaka","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0025","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1097\/PAS.0b013e3181f2d9b8","article-title":"Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor?","volume":"34","author":"Ip","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0030","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/PAS.0b013e31820f6d11","article-title":"Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor?","volume":"35","author":"Verine","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0035","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1177\/1066896911434548","article-title":"Sporadic hemangioblastoma of the kidney in a 29-year-old man","volume":"20","author":"Wang","year":"2012","journal-title":"Int J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0040","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1746-1596-7-39","article-title":"Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review","volume":"7","author":"Yin","year":"2012","journal-title":"Diagn Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0045","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1746-1596-7-49","article-title":"Sporadic hemangioblastoma of the kidney: a rare renal tumor","volume":"7","author":"Liu","year":"2012","journal-title":"Diagn Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0050","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/ejhg.2010.175","article-title":"von Hippel-Lindau disease: a clinical and scientific review","volume":"19","author":"Maher","year":"2011","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.humpath.2013.05.007_bb0055","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.humpath.2005.07.003","article-title":"Capillary hemangioblastoma of soft tissue: report of a case and review of the literature","volume":"36","author":"Patton","year":"2005","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0060","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/PAI.0b013e3181daad26","article-title":"Soft-tissue hemangioblastoma of the retroperitoneum: a case study and review of the literature","volume":"18","author":"Yoshida","year":"2010","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0065","first-page":"638","article-title":"A detailed immunohistochemical analysis of cerebellar hemangioblastoma: an undifferentiated mesenchymal tumor","volume":"2","author":"Frank","year":"1989","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0070","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00000478-198903000-00005","article-title":"Immunohistochemistry of capillary hemangioblastoma. Immunoperoxidase-labeled antibody staining resolves the differential diagnosis with metastatic renal cell carcinoma, but does not explain the histogenesis of the capillary hemangioblastoma","volume":"13","author":"Hufnagel","year":"1989","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0075","first-page":"999","article-title":"Peripheral nerve hemangioblastoma","volume":"11","author":"Giannini","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0080","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0046-8177(92)90351-3","article-title":"Fibrohistiocytic differentiation in capillary hemangioblastoma","volume":"23","author":"Nemes","year":"1992","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0085","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/modpathol.3800351","article-title":"Immunoreactivity of CD10 and inhibin alpha in differentiating hemangioblastoma of central nervous system from metastatic clear cell renal cell carcinoma","volume":"18","author":"Jung","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0090","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S1092-9134(00)90016-9","article-title":"Retroperitoneal peripheral hemangioblastoma: a case report and review of the literature","volume":"4","author":"Fanburg-Smith","year":"2000","journal-title":"Ann Diagn Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0095","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1097\/PAS.0b013e3181609d7d","article-title":"Immunohistochemical markers to distinguish between hemangioblastoma and metastatic clear-cell renal cell carcinoma in the brain: utility of aquaporin1 combined with cytokeratin AE1\/AE3 immunostaining","volume":"32","author":"Weinbreck","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0100","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0168-9525(01)02594-X","article-title":"Getting your Pax straight: Pax proteins in development and disease","volume":"18","author":"Chi","year":"2002","journal-title":"Trends Genet"},{"key":"10.1016\/j.humpath.2013.05.007_bb0105","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1242\/dev.110.2.643","article-title":"Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland","volume":"110","author":"Plachov","year":"1990","journal-title":"Development"},{"key":"10.1016\/j.humpath.2013.05.007_bb0110","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1242\/dev.116.3.611","article-title":"PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors","volume":"116","author":"Poleev","year":"1992","journal-title":"Development"},{"key":"10.1016\/j.humpath.2013.05.007_bb0115","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1038\/modpathol.2009.88","article-title":"Expression of PAX8 in normal and neoplastic renal tissues: an immunohistochemical study","volume":"22","author":"Tong","year":"2009","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0120","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/PAI.0b013e3182025f66","article-title":"Expression of PAX8 in normal and neoplastic tissues: a comprehensive immunohistochemical study","volume":"19","author":"Tacha","year":"2011","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0125","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1136\/jclinpath-2011-200508","article-title":"PAX8 is expressed in the majority of renal epithelial neoplasms: an immunohistochemical study of 223 cases using a mouse monoclonal antibody","volume":"65","author":"Hu","year":"2012","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0130","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/PAS.0b013e3182064d11","article-title":"PAX2(-)\/PAX8(-)\/inhibin A(+) immunoprofile in hemangioblastoma: a helpful combination in the differential diagnosis with metastatic clear cell renal cell carcinoma to the central nervous system","volume":"35","author":"Carney","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0135","series-title":"Urologic surgical pathology","year":"2014"},{"key":"10.1016\/j.humpath.2013.05.007_bb0140","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1097\/PAS.0b013e3181e8ce5b","article-title":"Xp11 translocation renal cell carcinoma (RCC): extended immunohistochemical profile emphasizing novel RCC markers","volume":"34","author":"Argani","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0145","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1097\/PAS.0b013e31827e17cb","article-title":"TFE3 break-apart FISH has a higher sensitivity for Xp11.2 translocation-associated renal cell carcinoma compared with TFE3 or cathepsin K immunohistochemical staining alone: expanding the morphologic spectrum","volume":"37","author":"Rao","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0150","series-title":"Atlas of genitourinary pathology","author":"Maclennan","year":"2011"},{"key":"10.1016\/j.humpath.2013.05.007_bb0155","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/PAS.0b013e318206f2a9","article-title":"Pure epithelioid PEComas (so-called epithelioid angiomyolipoma) of the kidney: a clinicopathologic study of 41 cases: detailed assessment of morphology and risk stratification","volume":"35","author":"Nese","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.05.007_bb0160","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/his.12059","article-title":"Cathepsin K expression in a wide spectrum of perivascular epithelioid cell neoplasms (PEComas): a clinicopathological study emphasizing extrarenal PEComas","volume":"62","author":"Rao","year":"2013","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2013.05.007_bb0165","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00428-013-1379-3","article-title":"Differential diagnosis of primary benign vascular tumors and\/or tumor-like lesions of the kidney: immunohistochemical stains should not be restricted to vascular and pan cytokeratin markers","volume":"462","author":"Verine","year":"2013","journal-title":"Virchows Arch"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817713001949?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817713001949?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T03:05:49Z","timestamp":1646017549000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817713001949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0046817713001949"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2013.05.007","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}