{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:21:10Z","timestamp":1792304470918,"version":"4.4.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.humpath.2013.07.033","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T17:55:24Z","timestamp":1381427724000},"page":"2814-2821","source":"Crossref","is-referenced-by-count":32,"title":["Utility of \u03b1-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas"],"prefix":"10.1016","volume":"44","author":[{"given":"Oluwole","family":"Fadare","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinita","family":"Parkash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Gwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina Z.","family":"Hanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke A.","family":"Jarboe,","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon X.","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles M.","family":"Quick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kojo R.","family":"Rawish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan L.","family":"Hecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed M.","family":"Desouki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2013.07.033_bb0005","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.plipres.2013.01.001","article-title":"\u03b1-Methylacyl-CoA racemase (AMACR): metabolic enzyme, drug metabolizer and cancer marker P504S","volume":"52","author":"Lloyd","year":"2013","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.humpath.2013.07.033_bb0010","first-page":"1677","article-title":"Identification of differentially expressed genes in human prostate cancer using subtraction and microarray","volume":"60","author":"Xu","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.humpath.2013.07.033_bb0015","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1097\/00000478-200111000-00007","article-title":"P504S\u2014a new molecular marker for the detection of prostate carcinoma","volume":"25","author":"Jiang","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0020","first-page":"2220","article-title":"a-Methylacyl-CoA racemase: a new molecular marker for prostate cancer","volume":"62","author":"Luo","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.humpath.2013.07.033_bb0025","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/00000478-200207000-00012","article-title":"Alpha-methylacyl-CoA racemase. A novel marker over-expressed in several human cancers and their precursor lesions","volume":"26","author":"Zhou","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0030","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/S0046-8177(03)00268-5","article-title":"Expression of a-methylacyl-CoA racemase (P504S) in various malignant neoplasms and normal tissues: a study of 761 cases","volume":"34","author":"Jiang","year":"2003","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0035","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/00129039-200509000-00007","article-title":"Utility of alpha-methylacyl coenzyme A racemase (p504s antibody) as a diagnostic immunohistochemical marker for cancer","volume":"13","author":"Nassar","year":"2005","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0040","doi-asserted-by":"crossref","first-page":"427","DOI":"10.5858\/134.3.427","article-title":"Pseudoneoplastic mimics of prostate and bladder carcinomas","volume":"134","author":"Hameed","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2013.07.033_bb0045","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00428-011-1095-9","article-title":"Alpha-methylacyl-CoA racemase (AMACR) expression in epithelial ovarian cancer","volume":"459","author":"Noske","year":"2011","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2013.07.033_bb0050","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/modpathol.3800260","article-title":"Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma","volume":"18","author":"Logani","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0055","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.humpath.2009.10.011","article-title":"Clear cell adenocarcinoma of the bladder and urethra: cases diffusely mimicking nephrogenic adenoma","volume":"41","author":"Herawi","year":"2010","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0060","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00428-012-1363-3","article-title":"Histology and immunohistochemistry of clear cell adenocarcinoma of the urethra: histogenesis and diagnostic problems","volume":"462","author":"Alexiev","year":"2013","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2013.07.033_bb0065","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.5858\/2008-132-1417-CCAOUB","article-title":"Clear cell adenocarcinoma of urinary bladder and urethra: another urinary tract lesion immunoreactive for P504S","volume":"132","author":"Sun","year":"2008","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2013.07.033_bb0070","series-title":"World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs","year":"2004"},{"key":"10.1016\/j.humpath.2013.07.033_bb0075","doi-asserted-by":"crossref","DOI":"10.1097\/PAS.0000000000000085","article-title":"Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility","author":"Fadare","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0080","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/PAI.0b013e31824973d1","article-title":"Diagnostic utility of hepatocyte nuclear factor 1-beta immunoreactivity in endometrial carcinomas: lack of specificity for endometrial clear cell carcinoma","volume":"20","author":"Fadare","year":"2012","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0085","first-page":"70","article-title":"Morphologic and other clinicopathologic features of endometrial clear cell carcinoma: a comprehensive analysis of 50 rigorously classified cases","volume":"3","author":"Fadare","year":"2013","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.humpath.2013.07.033_bb0090","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/PGP.0b013e3181ff9234","article-title":"Expression of tissue factor and heparanase in endometrial clear cell carcinoma: possible role for tissue factor in thromboembolic events","volume":"30","author":"Fadare","year":"2011","journal-title":"Int J Gynecol Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0095","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1097\/PAS.0b013e31825dd4b3","article-title":"The diagnosis of endometrial carcinomas with clear cells by gynecologic pathologists: an assessment of interobserver variability and associated morphologic features","volume":"36","author":"Fadare","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/his.12029","article-title":"High-grade endometrial carcinomas\u2014strategies for typing","volume":"62","author":"Soslow","year":"2013","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2013.07.033_bb0105","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1097\/PAS.0b013e31827f576a","article-title":"Poor interobserver reproducibility in the diagnosis of high-grade endometrial carcinoma","volume":"37","author":"Gilks","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0110","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1016\/S0002-9440(10)63605-X","article-title":"Expression profiling in ovarian clear cell carcinoma: identification of hepatocyte nuclear factor-1 beta as a molecular marker and a possible molecular target for therapy of ovarian clear cell carcinoma","volume":"163","author":"Tsuchiya","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0115","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.humpath.2006.12.018","article-title":"Immunohistochemical detection of hepatocyte nuclear factor 1beta in ovarian and endometrial clear-cell adenocarcinomas and nonneoplastic endometrium","volume":"38","author":"Yamamoto","year":"2007","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0120","doi-asserted-by":"crossref","DOI":"10.1038\/modpathol.2013.102","article-title":"Reproducibility of histological cell type in high-grade endometrial carcinoma","author":"Han","year":"2013","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0125","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1097\/PAS.0b013e31824a72c6","article-title":"Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-\u03b2","volume":"36","author":"Kenny","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0130","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/PAS.0b013e31821534b9","article-title":"Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus","volume":"35","author":"Park","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0135","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/his.12096","article-title":"ER+\/PR+\/TFF3+\/IMP3\u2212 immunoprofile distinguishes endometrioid from serous and clear cell carcinomas of the endometrium: a study of 401 cases","volume":"62","author":"Mhawech-Fauceglia","year":"2013","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2013.07.033_bb0140","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1158\/1535-7163.MCT-10-0902","article-title":"High-throughput screen identifies novel inhibitors of cancer biomarker \u03b1-methylacyl coenzyme A racemase (AMACR\/P504S)","volume":"10","author":"Wilson","year":"2011","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.humpath.2013.07.033_bb0145","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1479-5876-7-103","article-title":"Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer","volume":"7","author":"Honma","year":"2009","journal-title":"J Transl Med"},{"key":"10.1016\/j.humpath.2013.07.033_bb0150","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/PAI.0b013e318268d034","article-title":"\u03b1-Methylacyl-CoA racemase (AMACR) in gastric cancer: correlation with clinicopathologic data and disease-free survival","volume":"21","author":"Mroz","year":"2013","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0155","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1136\/jclinpath-2011-200489","article-title":"Alpha-methylacyl coenzyme A racemase overexpression in gallbladder carcinoma confers an independent prognostic indicator","volume":"65","author":"Wu","year":"2012","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0160","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.humpath.2006.12.016","article-title":"Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance","volume":"38","author":"Lin","year":"2007","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0165","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/pros.21432","article-title":"\u03b1-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study","volume":"72","author":"Barry","year":"2012","journal-title":"Prostate"},{"key":"10.1016\/j.humpath.2013.07.033_bb0170","article-title":"Prognostic value of alpha-methyl CoA racemase (AMACR) expression in renal cell carcinoma","author":"Eichelberg","year":"2011","journal-title":"World J Urol"},{"key":"10.1016\/j.humpath.2013.07.033_bb0175","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.5858\/2007-131-1555-MCRIPA","article-title":"Alpha-methylacyl CoA racemase in pulmonary adenocarcinoma, squamous cell carcinoma, and neuroendocrine tumors: expression and survival analysis","volume":"131","author":"Shilo","year":"2007","journal-title":"Arch Pathol Lab Med"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817713003225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817713003225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T18:26:37Z","timestamp":1646763997000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817713003225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0046817713003225"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2013.07.033","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}