{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:12:20Z","timestamp":1790651540793,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["humanpathol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.humpath.2014.03.007","type":"journal-article","created":{"date-parts":[[2014,4,4]],"date-time":"2014-04-04T01:31:55Z","timestamp":1396575115000},"page":"1597-1604","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Significance of signet ring cells in high-grade mucinous adenocarcinoma of the peritoneum from appendiceal origin"],"prefix":"10.1016","volume":"45","author":[{"given":"S. Joseph","family":"Sirintrapun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron U.","family":"Blackham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Russell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Votanopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward A.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim R.","family":"Geisinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Bergman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2014.03.007_bb0005","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1097\/00000478-199512000-00006","article-title":"Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. A clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to \u201cpseudomyxoma peritonei\u201d","volume":"19","author":"Ronnett","year":"1995","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0010","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.pas.0000202039.74837.7d","article-title":"Pseudomyxoma peritonei of appendiceal origin: a clinicopathologic analysis of 101 patients uniformly treated at a single institution, with literature review","volume":"30","author":"Bradley","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0090","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1309\/601K2L2T7CR5U7G1","article-title":"Pleuropulmonary involvement in pseudomyxoma peritonei: morphologic assessment and literature review","volume":"127","author":"Geisinger","year":"2007","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0020","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1200\/JCO.2011.39.7166","article-title":"Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy","volume":"30","author":"Chua","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0025","series-title":"AJCC Cancer Staging Manual","year":"2010"},{"key":"10.1016\/j.humpath.2014.03.007_bb0030","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1245\/s10434-012-2321-7","article-title":"Clinicopathology and outcomes for mucinous and signet ring colorectal adenocarcinoma: analysis from the National Cancer Data Base","volume":"19","author":"Hyngstrom","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0035","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/SLA.0b013e3182a69f7e","article-title":"Mucinous and signet ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis","volume":"258","author":"Nitsche","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.humpath.2014.03.007_bb0040","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/PAS.0b013e3182851e2b","article-title":"Signet ring cell colorectal carcinoma: a distinct subset of mucin-poor microsatellite-stable signet ring cell carcinoma associated with dismal prognosis","volume":"37","author":"Hartman","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0045","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.surg.2012.07.027","article-title":"Predictors of survival in patients with high-grade peritoneal metastases undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy","volume":"152","author":"Van Sweringen","year":"2012","journal-title":"Surgery"},{"key":"10.1016\/j.humpath.2014.03.007_bb0050","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1093\/annonc\/mdr279","article-title":"Systemic chemotherapy and surgical cytoreduction for poorly differentiated and signet ring cell adenocarcinomas of the appendix","volume":"23","author":"Lieu","year":"2012","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0055","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1245\/s10434-012-2238-1","article-title":"Importance of histologic subtype in the staging of appendiceal tumors","volume":"19","author":"Turaga","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0060","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1002\/cncr.24320","article-title":"A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status","volume":"115","author":"Wittekind","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2014.03.007_bb0065","series-title":"WHO Classification of Tumours of the Digestive System","article-title":"Adenocarcinoma of the appendix","author":"Carr","year":"2010"},{"key":"10.1016\/j.humpath.2014.03.007_bb0070","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.5858\/arpa.2011-0034-RA","article-title":"Mucinous neoplasms of the appendix and peritoneum","volume":"135","author":"Panarelli","year":"2011","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2014.03.007_bb0075","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1245\/s10434-007-9691-2","article-title":"Pseudomyxoma peritonei: clinical pathological and biological prognostic factors in patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC)","volume":"15","author":"Baratti","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.humpath.2014.03.007_bb0080","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/SLA.0b013e31818eec64","article-title":"Pseudomyxoma peritonei: biological features are the dominant prognostic determinants after complete cytoreduction and hyperthermic intraperitoneal chemotherapy","volume":"249","author":"Baratti","year":"2009","journal-title":"Ann Surg"},{"key":"10.1016\/j.humpath.2014.03.007_bb0085","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1097\/PAS.0b013e3181af6067","article-title":"Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence","volume":"33","author":"Pai","year":"2009","journal-title":"Am J Surg Pathol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817714001361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817714001361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T00:53:32Z","timestamp":1538700812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817714001361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S0046817714001361"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2014.03.007","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Significance of signet ring cells in high-grade mucinous adenocarcinoma of the peritoneum from appendiceal origin","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2014.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}