{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T14:50:41Z","timestamp":1785682241784,"version":"3.56.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.humpath.2015.07.023","type":"journal-article","created":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T01:02:42Z","timestamp":1439341362000},"page":"1829-1835","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Significantly increased PELP1 protein expression in primary and metastatic triple-negative breast carcinoma: comparison with GATA3 expression and PELP1's potential role in triple-negative breast carcinoma"],"prefix":"10.1016","volume":"46","author":[{"given":"Daniel N.","family":"Dang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venetia","family":"Sarode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle H.","family":"Molberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratna K.","family":"Vadlamudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2015.07.023_bb0005","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1001\/jama.295.21.2492","article-title":"Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study","volume":"21","author":"Carey","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.humpath.2015.07.023_bb0010","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s10549-013-2550-x","article-title":"Black race as a prognostic factor in triple-negative breast cancer patients treated with breast-conserving therapy: a large, single-institution retrospective analysis","volume":"2","author":"Perez","year":"2013","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2015.07.023_bb0015","doi-asserted-by":"crossref","first-page":"860","DOI":"10.5858\/133.6.860","article-title":"Basal-like breast carcinoma: from expression profiling to routine practice","volume":"6","author":"Rakha","year":"2009","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2015.07.023_bb0020","first-page":"18","article-title":"Are mammaglobin and GCDFP-15 sensitive markers for diagnosis of metastatic basal-like triple negative breast carcinomas?","volume":"1","author":"Rakhshani","year":"2014","journal-title":"Turk Patoloji Derg"},{"key":"10.1016\/j.humpath.2015.07.023_bb0025","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1309\/AJCPMFR6OA8ICHNH","article-title":"Relationship between molecular subtype of invasive breast carcinoma and expression of gross cystic disease fluid protein 15 and mammaglobin","volume":"4","author":"Lewis","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0030","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1200\/JCO.2007.14.4147","article-title":"Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer","volume":"8","author":"Liedtke","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0035","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1158\/1078-0432.CCR-06-1109","article-title":"The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes","volume":"8","author":"Carey","year":"2007","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.humpath.2015.07.023_bb0040","article-title":"Prognostic impact of clinicopathologic parameters in stage II\/III breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancer","volume":"203","author":"Keam","year":"2007","journal-title":"BMC Cancer"},{"key":"10.1016\/j.humpath.2015.07.023_bb0045","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3892\/etm.2011.212","article-title":"Pathological tumor response to neoadjuvant chemotherapy using anthracycline and taxanes in patients with triple-negative breast cancer","volume":"2","author":"Sakuma","year":"2011","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.humpath.2015.07.023_bb0050","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1177\/1947601911404223","article-title":"GATA transcription factors and cancer","volume":"12","author":"Zheng","year":"2010","journal-title":"Genes Cancer"},{"key":"10.1016\/j.humpath.2015.07.023_bb0055","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ccr.2008.01.011","article-title":"GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model","volume":"2","author":"Kouros-Mehr","year":"2008","journal-title":"Cancer Cell"},{"key":"10.1016\/j.humpath.2015.07.023_bb0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1309\/AJCP5UAFMSA9ZQBZ","article-title":"Immunohistochemical evaluation of GATA3 expression in tumors and normal tissues: a useful immunomarker for breast and urothelial carcinomas","volume":"1","author":"Liu","year":"2012","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0065","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/modpathol.2010.38","article-title":"A study of immunohistochemical differential expression in pulmonary and mammary carcinomas","volume":"5","author":"Yang","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0070","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1016\/j.humpath.2014.06.022","article-title":"Diagnostic utility and sensitivities of GATA3 antibodies in triple-negative breast cancer","volume":"11","author":"Krings","year":"2014","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0075","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1016\/j.humpath.2010.06.010","article-title":"Higher levels of GATA3 predict better survival in women with breast cancer","volume":"12","author":"Yoon","year":"2010","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1158\/1541-7786.MCR-11-0456","article-title":"Significance of PELP1 in ER-negative breast cancer metastasis","volume":"1","author":"Roy","year":"2012","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.humpath.2015.07.023_bb0085","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1101\/gad.1424806","article-title":"Sensors and signals: a coactivator\/corepressor\/epigenetic code for integrating signal-dependent programs of transcriptional response","volume":"11","author":"Rosenfeld","year":"2006","journal-title":"Genes Dev"},{"key":"10.1016\/j.humpath.2015.07.023_bb0090","doi-asserted-by":"crossref","first-page":"38272","DOI":"10.1074\/jbc.M103783200","article-title":"Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha","volume":"41","author":"Vadlamudi","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.humpath.2015.07.023_bb0095","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/onc.2013.579","article-title":"Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor\u2013containing transcription complexes","volume":"4","author":"Daniel","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.humpath.2015.07.023_bb0100","first-page":"666","article-title":"Potential prognostic tumor biomarkers in triple-negative breast carcinoma","volume":"5","author":"Peng","year":"2012","journal-title":"Beijing Da Xue Xue Bao"},{"key":"10.1016\/j.humpath.2015.07.023_bb0105","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1158\/1078-0432.CCR-12-3826","article-title":"Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer","volume":"22","author":"Skor","year":"2013","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.humpath.2015.07.023_bb0110","doi-asserted-by":"crossref","first-page":"5505","DOI":"10.1158\/0008-5472.CAN-06-3647","article-title":"Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid\u2013, leucine-rich protein 1\/modulator of the nongenomic actions of the estrogen receptor","volume":"11","author":"Rajhans","year":"2007","journal-title":"Cancer Res"},{"key":"10.1016\/j.humpath.2015.07.023_bb0115","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1309\/AJCP9DV3EVZUATFV","volume":"2","author":"Han","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0120","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1309\/AJCP8AVF8FDPTZLH","article-title":"Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor\u2013expressing triple-negative breast carcinoma","volume":"4","author":"Sutton","year":"2012","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0125","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1309\/AJCPRMD3ARUO5WPN","article-title":"Intratumoral expression level of epidermal growth factor receptor and cytokeratin 5\/6 is significantly associated with nodal and distant metastases in patients with basal-like triple-negative breast carcinoma","volume":"5","author":"Sutton","year":"2010","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0130","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.humpath.2013.11.013","article-title":"Ki-67 expression is increased in p16-expressing triple-negative breast carcinoma and correlates with p16 only in p53-negative tumors","volume":"4","author":"Sugianto","year":"2014","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0135","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1309\/AJCP0Q9UQTEESLHN","article-title":"Immunohistochemical evaluation of GATA-3 expression in ER-negative breast carcinomas","volume":"5","author":"Liu","year":"2014","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0140","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1309\/AJCP8H2VBDSCIOBF","article-title":"Semiquantitative GATA-3 immunoreactivity in breast, bladder, gynecologic tract, and other cytokeratin 7\u2013positive carcinomas","volume":"1","author":"Clark","year":"2014","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0145","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/j.humpath.2012.11.003","article-title":"GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas","volume":"7","author":"Cimino-Mathews","year":"2013","journal-title":"Hum Pathol"},{"issue":"Suppl 2s","key":"10.1016\/j.humpath.2015.07.023_bb0150","first-page":"47A","article-title":"GATA3, mammaglobin, and GCDFP-15 expression in subtypes of breast ductal carcinoma in African American women","volume":"27","author":"Esnakula","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2015.07.023_bb0155","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10549-009-0419-9","article-title":"The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype","volume":"3","author":"Habashy","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2015.07.023_bb0160","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1038\/onc.2013.332","article-title":"Significance of PELP1\/HDAC2\/miR-200 regulatory network in EMT and metastasis of breast cancer","volume":"28","author":"Roy","year":"2014","journal-title":"Oncogene"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817715002865?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817715002865?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T16:34:29Z","timestamp":1758645269000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817715002865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0046817715002865"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2015.07.023","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Significantly increased PELP1 protein expression in primary and metastatic triple-negative breast carcinoma: comparison with GATA3 expression and PELP1's potential role in triple-negative breast carcinoma","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2015.07.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}