{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:09:27Z","timestamp":1786990167145,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["humanpathol.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.humpath.2016.06.014","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T06:56:28Z","timestamp":1467183388000},"page":"7-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["A subset of fat-predominant angiomyolipomas label for MDM2 : a potential diagnostic pitfall"],"prefix":"10.1016","volume":"57","author":[{"given":"Rebecca J.","family":"Asch-Kendrick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashi","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Goldblum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajni","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan I.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Argani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Cimino-Mathews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2016.06.014_bb0005","series-title":"WHO classification of tumours: pathology and genetics of tumours of the urinary system and male genital organs","first-page":"65","article-title":"Angiomyolipoma","author":"Martignoni","year":"2004"},{"key":"10.1016\/j.humpath.2016.06.014_bb0010","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00428-007-0509-1","article-title":"PEComas: the past, the present and the future","volume":"452","author":"Martignoni","year":"2008","journal-title":"Virchows Arch"},{"key":"10.1016\/j.humpath.2016.06.014_bb0015","doi-asserted-by":"crossref","first-page":"751","DOI":"10.5858\/2001-125-0751-RA","article-title":"Renal angiomyolipoma: further immunophenotypic characterization of an expanding morphologic spectrum","volume":"125","author":"Stone","year":"2001","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2016.06.014_bb0020","doi-asserted-by":"crossref","first-page":"769","DOI":"10.2214\/ajr.179.3.1790769","article-title":"CT differentiation of large exophytic renal angiomyolipomas and perirenal liposarcomas","volume":"179","author":"Israel","year":"2002","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0025","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/ajcp\/92.6.805","article-title":"Massive retroperitoneal angiomyolipoma. A lesion that may be confused with well-differentiated liposarcoma","volume":"92","author":"Hruban","year":"1989","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0030","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.path.2015.05.008","article-title":"Diagnostically challenging \"fatty\" retroperitoneal tumors","volume":"8","author":"Fritchie","year":"2015","journal-title":"Surg Pathol Clin"},{"key":"10.1016\/j.humpath.2016.06.014_bb0035","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1002\/1097-0142(19930515)71:10<3091::AID-CNCR2820711032>3.0.CO;2-5","article-title":"Renal angiomyolipomas and HMB-45 reactivity","volume":"71","author":"Ashfaq","year":"1993","journal-title":"Cancer"},{"key":"10.1016\/j.humpath.2016.06.014_bb0040","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/00313029109063563","article-title":"Melanocyte-marker-HMB-45 is regularly expressed in angiomyolipoma of the kidney","volume":"23","author":"Pea","year":"1991","journal-title":"Pathology"},{"key":"10.1016\/j.humpath.2016.06.014_bb0045","first-page":"842","article-title":"Angiomyolipomas: the nature and expression of the HMB45 antigen","volume":"7","author":"Sturtz","year":"1994","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0050","first-page":"699","article-title":"Comparison of melanoma antigen recognized by T cells (MART-1) to HMB-45: additional evidence to support a common lineage for angiomyolipoma, lymphangiomyomatosis, and clear cell sugar tumor","volume":"11","author":"Fetsch","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0055","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00000478-200101000-00007","article-title":"Immunohistochemical study of microphthalmia transcription factor and tyrosinase in angiomyolipoma of the kidney, renal cell carcinoma, and renal and retroperitoneal sarcomas: comparative evaluation with traditional diagnostic markers","volume":"25","author":"Zavala-Pompa","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0060","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/modpathol.2011.136","article-title":"Cathepsin K expression in the spectrum of perivascular epithelioid cell (PEC) lesions of the kidney","volume":"25","author":"Martignoni","year":"2012","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0065","series-title":"Enzinger & Weiss's soft tissue tumors","first-page":"484","article-title":"Liposarcoma","author":"Goldblum","year":"2014"},{"key":"10.1016\/j.humpath.2016.06.014_bb0070","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1097\/PAS.0b013e3182417330","article-title":"Diagnostic utility of p16, CDK4, and MDM2 as an immunohistochemical panel in distinguishing well-differentiated and dedifferentiated liposarcomas from other adipocytic tumors","volume":"36","author":"Thway","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0075","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1097\/01.pas.0000170343.09562.39","article-title":"MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data","volume":"29","author":"Binh","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0080","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/modpathol.2008.84","article-title":"Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms","volume":"21","author":"Weaver","year":"2008","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0085","first-page":"2231","article-title":"p53 mutation and MDM2 amplification in human soft tissue sarcomas","volume":"53","author":"Leach","year":"1993","journal-title":"Cancer Res"},{"key":"10.1016\/j.humpath.2016.06.014_bb0090","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/modpathol.2010.106","article-title":"Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma?","volume":"23","author":"Weaver","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0095","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/0092-8674(93)90618-Z","article-title":"Identification and characterization of the tuberous sclerosis gene on chromosome 16","volume":"75","author":"Consortium","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.humpath.2016.06.014_bb0100","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/PAS.0b013e3181d90370","article-title":"Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy","volume":"34","author":"Brimo","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0105","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1097\/00000478-199710000-00001","article-title":"Epithelioid angiomyolipoma of the kidney: a report of five cases with a prominent and diagnostically confusing epithelioid smooth muscle component","volume":"21","author":"Eble","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0110","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1046\/j.1365-2559.1996.d01-421.x","article-title":"Epithelioid cell variant of renal angiomyolipoma","volume":"28","author":"Mai","year":"1996","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2016.06.014_bb0115","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1097\/01.pas.0000194298.19839.b4","article-title":"Angiomyolipoma with epithelial cysts (AMLEC): a distinct cystic variant of angiomyolipoma","volume":"30","author":"Fine","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0120","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/PAS.0b013e31817ed7a6","article-title":"Renal angiomyolipoma: clinicopathologic study of 194 cases with emphasis on the epithelioid histology and tuberous sclerosis association","volume":"33","author":"Aydin","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0125","first-page":"113","article-title":"Well-differentiated liposarcoma of the retroperitoneum: a clinicopathologic analysis of 20 cases, with particular attention to the extent of low-grade dedifferentiation","volume":"10","author":"Elgar","year":"1997","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0130","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/ajcp\/102.5.677","article-title":"Well-differentiated liposarcoma. The Mayo Clinic experience with 58 cases","volume":"102","author":"Lucas","year":"1994","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0135","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1097\/00000478-199211000-00003","article-title":"Well-differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum, and miscellaneous sites. A follow-up study of 92 cases with analysis of the incidence of \u201cdedifferentiation\"","volume":"16","author":"Weiss","year":"1992","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0140","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1309\/AJCPDTRTO2Z4UEXD","article-title":"A broad survey of cathepsin K immunoreactivity in human neoplasms","volume":"139","author":"Zheng","year":"2013","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2016.06.014_bb0145","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1101\/gad.1941710","article-title":"The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor","volume":"24","author":"Manfredi","year":"2010","journal-title":"Genes Dev"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817716301344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817716301344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T06:38:43Z","timestamp":1656743923000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817716301344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":29,"alternative-id":["S0046817716301344"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2016.06.014","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A subset of fat-predominant angiomyolipomas label for MDM2: a potential diagnostic pitfall","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2016.06.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}