{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T04:23:37Z","timestamp":1771561417699,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["humanpathol.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.humpath.2017.01.007","type":"journal-article","created":{"date-parts":[[2017,1,31]],"date-time":"2017-01-31T19:05:47Z","timestamp":1485889547000},"page":"180-186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Transforming growth factor \u03b2 \u2013 and interleukin 13\u2013producing mast cells are associated with fibrosis in bone marrow"],"prefix":"10.1016","volume":"62","author":[{"given":"Shoko","family":"Nakayama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiji","family":"Yokote","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuya","family":"Hiraoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshikazu","family":"Akioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uta","family":"Nishiwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuji","family":"Miyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Iwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayami","family":"Fumimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Hatooka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuichiro","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motomu","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2017.01.007_bb0005","first-page":"1128","article-title":"European consensus on grading bone marrow fibrosis and assessment of cellularity","volume":"156","author":"Thiele","year":"2005","journal-title":"Haematologica"},{"key":"10.1016\/j.humpath.2017.01.007_bb0010","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1038\/sj.leu.2403875","article-title":"Involvement of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic syndrome with myelofibrosis","volume":"19","author":"Akiyama","year":"2005","journal-title":"Leukemia"},{"key":"10.1016\/j.humpath.2017.01.007_bb0015","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.ccr.2005.03.023","article-title":"Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis","volume":"7","author":"Levine","year":"2005","journal-title":"Cancer Cell"},{"key":"10.1016\/j.humpath.2017.01.007_bb0020","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1056\/NEJMoa1002028","article-title":"Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis","volume":"363","author":"Verstovsek","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humpath.2017.01.007_bb0025","doi-asserted-by":"publisher","first-page":"3472","DOI":"10.1182\/blood-2006-04-018879","article-title":"MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients","volume":"108","author":"Pardanani","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2017.01.007_bb0030","doi-asserted-by":"publisher","first-page":"8520","DOI":"10.1200\/JCO.2004.00.9316","article-title":"Pathogenesis of myelofibrosis with myeloid metaplasia","volume":"23","author":"Tefferi","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0035","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/j.1365-2141.1989.tb04310.x","article-title":"Transforming growth factor-beta regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts","volume":"72","author":"Kimura","year":"1989","journal-title":"Br J Haematol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0040","doi-asserted-by":"publisher","first-page":"3493","DOI":"10.1182\/blood-2004-04-1320","article-title":"A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-beta1 in the development of myelofibrosis","volume":"105","author":"Vannucchi","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2017.01.007_bb0045","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1002\/(SICI)1096-8652(199810)59:2<133::AID-AJH6>3.0.CO;2-Z","article-title":"Systemic transforming growth factor-beta in patients with bone marrow fibrosis\u2014pathophysiological implications","volume":"59","author":"Rameshwar","year":"1998","journal-title":"Am J Hematol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0050","doi-asserted-by":"publisher","first-page":"450","DOI":"10.3109\/10428194.2013.805329","article-title":"Anti-transforming growth factor-\u03b2 therapy in patients with myelofibrosis","volume":"55","author":"Mascarenhas","year":"2014","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.humpath.2017.01.007_bb0055","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1159\/000317102","article-title":"Mast cell infiltration is involved in renal interstitial fibrosis in a rat model of protein-overload nephropathy","volume":"33","author":"Li","year":"2010","journal-title":"Kidney Blood Press Res"},{"key":"10.1016\/j.humpath.2017.01.007_bb0060","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.mehy.2006.10.059","article-title":"Mast cell, a promising therapeutic target in tubulointerstitial fibrosis","volume":"69","author":"Li","year":"2007","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.humpath.2017.01.007_bb0065","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1056\/NEJMra1104650","article-title":"IgG4-related disease","volume":"366","author":"Stone","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.humpath.2017.01.007_bb0070","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1038\/modpathol.2013.236","article-title":"T helper 2 and regulatory T-cell cytokine production by mast cells: a key factor in the pathogenesis of IgG4-related disease","volume":"27","author":"Takeuchi","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0075","doi-asserted-by":"publisher","first-page":"7696","DOI":"10.1038\/srep07696","article-title":"Interleukin 13\u2013positive mast cells are increased in immunoglobulin G4\u2013related sialadenitis","volume":"5","author":"Takeuchi","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.humpath.2017.01.007_bb0080","doi-asserted-by":"publisher","first-page":"120","DOI":"10.3389\/fimmu.2012.00120","article-title":"Mast cell: an emerging partner in immune interaction","volume":"3","author":"Gri","year":"2012","journal-title":"Front Immunol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0085","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s11926-003-0043-3","article-title":"Mast cells in the pathogenesis of fibrosis","volume":"5","author":"Gruber","year":"2003","journal-title":"Curr Rheumatol Rep"},{"key":"10.1016\/j.humpath.2017.01.007_bb0090","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1177\/0394632016644447","article-title":"Role of mast cells in fibrosis of classical Hodgkin lymphoma","volume":"29","author":"Nakayama","year":"2016","journal-title":"Int J Immunopathol Pharmacol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0095","doi-asserted-by":"publisher","first-page":"3495","DOI":"10.1182\/blood-2002-04-1133","article-title":"Prominent role of TGF-beta 1 in thrombopoietin-induced myelofibrosis in mice","volume":"100","author":"Chagraoui","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2017.01.007_bb0100","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1182\/blood-2006-12-064626","article-title":"Pivotal contributions of megakaryocytes to the biology of idiopathic myelofibrosis","volume":"110","author":"Ciurea","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.humpath.2017.01.007_bb0105","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1006\/clim.2001.5008","article-title":"Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment","volume":"99","author":"Sime","year":"2001","journal-title":"Clin Immunol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0110","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1038\/nri1412","article-title":"Fibrotic disease and the T(H)1\/T(H)2 paradigm","volume":"4","author":"Wynn","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.humpath.2017.01.007_bb0115","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/biof.1117","article-title":"Role of interleukin-13 in fibrosis, particularly systemic sclerosis","volume":"39","author":"O'Reilly","year":"2013","journal-title":"Biofactors"},{"key":"10.1016\/j.humpath.2017.01.007_bb0120","first-page":"634","article-title":"Mast cell burden and reticulin fibrosis in the myeloproliferative neoplasms: a computer-assisted image analysis study","volume":"205","author":"Ahmed","year":"2009","journal-title":"Pathology"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004681771730028X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004681771730028X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T18:51:39Z","timestamp":1536087099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004681771730028X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":24,"alternative-id":["S004681771730028X"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2017.01.007","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transforming growth factor \u03b2\u2013 and interleukin 13\u2013producing mast cells are associated with fibrosis in bone marrow","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2017.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}