{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T13:59:26Z","timestamp":1785679166124,"version":"3.56.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["humanpathol.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.humpath.2017.07.015","type":"journal-article","created":{"date-parts":[[2017,8,4]],"date-time":"2017-08-04T19:46:44Z","timestamp":1501876004000},"page":"160-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":61,"special_numbering":"C","title":["The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell\/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center"],"prefix":"10.1016","volume":"67","author":[{"given":"Alberto M.","family":"Marchevsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nolwenn","family":"LeStang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenzo","family":"Hiroshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Pelosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Attanoos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Churg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucian","family":"Chirieac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Dacic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliya","family":"Husain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andras","family":"Khoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Klebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvie","family":"Lantuejoul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Roggli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Vignaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Weynard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Sauter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasuzi","family":"Nabeshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francoise","family":"Galateau-Salle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2017.07.015_bb0005","series-title":"WHO classification of tumors of the lung, pleura, thymus and heart","author":"Travis","year":"2015"},{"key":"10.1016\/j.humpath.2017.07.015_bb0010","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/modpathol.2012.39","article-title":"Pleomorphic mesothelioma: report of 10 cases","volume":"25","author":"Ordonez","year":"2012","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0015","doi-asserted-by":"crossref","DOI":"10.5858\/arpa.2017-0124-RA","article-title":"Guidelines for pathologic diagnosis of malignant mesothelioma: 2017 update of the consensus statement from the International Mesothelioma Interest Group","author":"Husain","year":"2017","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2017.07.015_bb0020","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.lungcan.2013.12.009","article-title":"How useful is GLUT-1 in differentiating mesothelial hyperplasia and fibrosing pleuritis from epithelioid and sarcomatoid mesotheliomas? An international collaborative study","volume":"83","author":"Husain","year":"2014","journal-title":"Lung Cancer"},{"key":"10.1016\/j.humpath.2017.07.015_bb0025","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1046\/j.1365-2559.2000.00981.x","article-title":"Anti-mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms","volume":"37","author":"Attanoos","year":"2000","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2017.07.015_bb0030","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1046\/j.1365-2559.2003.01583.x","article-title":"Sarcomatoid mesothelioma and its histological mimics: a comparative immunohistochemical study","volume":"42","author":"Lucas","year":"2003","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2017.07.015_bb0035","first-page":"205","article-title":"Expression of mesothelial markers in malignant mesotheliomas: an immunohistochemical evaluation of 173 cases","volume":"55","author":"Soomro","year":"2005","journal-title":"J Pak Med Assoc"},{"key":"10.1016\/j.humpath.2017.07.015_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/modpathol.3800736","article-title":"D2-40 and calretinin \u2013 a tissue microarray analysis of 341 malignant mesotheliomas with emphasis on sarcomatoid differentiation","volume":"20","author":"Hinterberger","year":"2007","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1440-1827.2007.02193.x","article-title":"Differential diagnosis of sarcomatoid mesothelioma from true sarcoma and sarcomatoid carcinoma using immunohistochemistry","volume":"58","author":"Kushitani","year":"2008","journal-title":"Pathol Int"},{"key":"10.1016\/j.humpath.2017.07.015_bb0050","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/PAS.0b013e31814faacf","article-title":"Podoplanin is a better immunohistochemical marker for sarcomatoid mesothelioma than calretinin","volume":"32","author":"Padgett","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0055","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.1365-2559.2009.03298.x","article-title":"Value of immunohistochemistry in the differential diagnosis of pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma","volume":"54","author":"Takeshima","year":"2009","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2017.07.015_bb0060","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/modpathol.2009.180","article-title":"Sarcomatoid mesothelioma: a clinical-pathologic correlation of 326 cases","volume":"23","author":"Klebe","year":"2010","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0065","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1309\/AJCP0B3YJBXWXJII","article-title":"Value of claudin-4 immunostaining in the diagnosis of mesothelioma","volume":"139","author":"Ordonez","year":"2013","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0070","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/modpathol.2016.181","article-title":"MUC4, a novel immunohistochemical marker identified by gene expression profiling, differentiates pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma","volume":"30","author":"Amatya","year":"2017","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0075","first-page":"14","article-title":"The immunohistochemical characterization of sarcomatoid malignant mesothelioma of the pleura","volume":"1","author":"Chirieac","year":"2011","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.humpath.2017.07.015_bb0080","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.humpath.2013.09.005","article-title":"Immunohistochemical study of 36 cases of pulmonary sarcomatoid carcinoma--sensitivity of TTF-1 is superior to napsin","volume":"45","author":"Terra","year":"2014","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.humpath.2016.08.003","article-title":"Spindle cell and pleomorphic (\"sarcomatoid\") carcinomas of the lung: an immunohistochemical analysis of 86 cases","volume":"59","author":"Weissferdt","year":"2017","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0090","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1136\/jclinpath-2015-203184","article-title":"An immunohistochemical comparison of two TTF-1 monoclonal antibodies in atypical squamous lesions and sarcomatoid carcinoma of the lung, and pleural malignant mesothelioma","volume":"69","author":"Klebe","year":"2016","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0095","doi-asserted-by":"crossref","first-page":"E379","DOI":"10.21037\/jtd.2016.03.92","article-title":"Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor","volume":"8","author":"Kim","year":"2016","journal-title":"J Thorac Dis"},{"key":"10.1016\/j.humpath.2017.07.015_bb0100","first-page":"18367","article-title":"Massive localized malignant pleural mesothelioma (LMPM): manifestations on computed tomography in 6 cases","volume":"8","author":"Yao","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"10.1016\/j.humpath.2017.07.015_bb0105","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1046\/j.1440-1827.2001.01250.x","article-title":"Localized malignant mesothelioma of the pleura","volume":"51","author":"Okamura","year":"2001","journal-title":"Pathol Int"},{"key":"10.1016\/j.humpath.2017.07.015_bb0110","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1097\/01.pas.0000165529.78945.dc","article-title":"Localized malignant mesothelioma","volume":"29","author":"Allen","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0115","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/00000478-199404000-00004","article-title":"Localized malignant mesothelioma. A clinicopathologic and flow cytometric study","volume":"18","author":"Crotty","year":"1994","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.humpath.2016.09.002","article-title":"Evidence-based pathology in its second decade: toward probabilistic cognitive computing","volume":"61","author":"Marchevsky","year":"2017","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0125","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/PAI.0b013e31825e0013","article-title":"Melan a (A103) is not a marker of mesothelioma","volume":"21","author":"Ordonez","year":"2013","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0130","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/modpathol.2011.159","article-title":"Mesotheliomas with crystalloid structures: report of nine cases, including one with oncocytic features","volume":"25","author":"Ordonez","year":"2012","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0135","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.5858\/133.8.1317","article-title":"Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the international mesothelioma interest group","volume":"133","author":"Husain","year":"2009","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2017.07.015_bb0140","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/modpathol.3800543","article-title":"Mesothelioma with rhabdoid features: an ultrastructural and immunohistochemical study of 10 cases","volume":"19","author":"Ordonez","year":"2006","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0145","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.humpath.2005.01.019","article-title":"D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma","volume":"36","author":"Ordonez","year":"2005","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0150","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.humpath.2003.11.013","article-title":"The diagnostic utility of immunohistochemistry in distinguishing between mesothelioma and renal cell carcinoma: a comparative study","volume":"35","author":"Ordonez","year":"2004","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0155","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/01.MP.0000056981.16578.C3","article-title":"Value of mesothelin immunostaining in the diagnosis of mesothelioma","volume":"16","author":"Ordonez","year":"2003","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0160","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1097\/00000478-199712000-00016","article-title":"Malignant peripheral nerve sheath tumor of the pleura with epithelial and rhabdomyoblastic differentiation: report of a case clinically simulating mesothelioma","volume":"21","author":"Ordonez","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0165","first-page":"559","article-title":"Expression of thrombomodulin, calretinin, cytokeratin 5\/6, D2-40 and WT-1 in a series of primary carcinomas of the lung: an immunohistochemical study in comparison with epithelioid pleural mesothelioma","volume":"100","author":"Comin","year":"2014","journal-title":"Tumori"},{"key":"10.1016\/j.humpath.2017.07.015_bb0170","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1097\/00000478-200302000-00002","article-title":"Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleura","volume":"27","author":"Miettinen","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2017.07.015_bb0175","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/PAS.0000000000000825","article-title":"GATA3 immunohistochemistry for distinguishing sarcomatoid and desmoplastic mesothelioma from sarcomatoid carcinoma of the lung","volume":"41","author":"Berg","year":"2017","journal-title":"Am J Surg Pathol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817717302678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817717302678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T20:29:26Z","timestamp":1659299366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817717302678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":35,"alternative-id":["S0046817717302678"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2017.07.015","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell\/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2017.07.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}