{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:28:24Z","timestamp":1788406104499,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["humanpathol.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.humpath.2018.03.007","type":"journal-article","created":{"date-parts":[[2018,3,17]],"date-time":"2018-03-17T03:49:24Z","timestamp":1521258564000},"page":"91-99","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"special_numbering":"C","title":["Spectrum of findings in orchiectomy specimens of persons undergoing gender confirmation surgery"],"prefix":"10.1016","volume":"76","author":[{"given":"Andres","family":"Matoso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binny","family":"Khandakar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songyang","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li J.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara A","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamlal","family":"Mangray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abul Ala Syed Rifat","family":"Mannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeny","family":"Yakirevich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2018.03.007_bb0005","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.jsxm.2017.01.022","article-title":"Quality of life and patient satisfaction following male-to-female sex reassignment surgery","volume":"14","author":"Papadopulos","year":"2017","journal-title":"J Sex Med"},{"key":"10.1016\/j.humpath.2018.03.007_bb0010","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1210\/jc.2009-0345","article-title":"Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline","volume":"94","author":"Hembree","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.humpath.2018.03.007_bb0015","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1046\/j.1464-410x.2000.00934.x","article-title":"Vaginoplasty in male transsexuals using penile skin and a urethral flap","volume":"86","author":"Perovic","year":"2000","journal-title":"BJU Int"},{"key":"10.1016\/j.humpath.2018.03.007_bb0020","first-page":"143","article-title":"Vaginoplasty in male to female sex change operations","volume":"42-43","author":"Perovic","year":"1995","journal-title":"Acta Chir Iugosl"},{"key":"10.1016\/j.humpath.2018.03.007_bb0025","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1097\/00006534-199605000-00018","article-title":"Labial masses following vaginoplasty in male transsexuals: the differential diagnosis","volume":"97","author":"Hage","year":"1996","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.humpath.2018.03.007_bb0030","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/00006534-199304000-00021","article-title":"Male to female surgery: a new contribution to operative technique","volume":"91","author":"Perovic","year":"1993","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.humpath.2018.03.007_bb0035","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00006534-198066030-00015","article-title":"One-stage reconstruction of the vagina with penile skin as an island flap in male transsexuals","volume":"66","author":"Meyer","year":"1980","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.humpath.2018.03.007_bb0040","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/01.sap.0000258953.00234.50","article-title":"Do histologic changes in the skin-lined neovagina of male-to-female transsexuals really occur?","volume":"59","author":"Dekker","year":"2007","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.humpath.2018.03.007_bb0045","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/00000478-200001000-00009","article-title":"Short-term and long-term histologic effects of castration and estrogen treatment on breast tissue of 14 male-to-female transsexuals in comparison with two chemically castrated men","volume":"24","author":"Kanhai","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0050","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/BF00735221","article-title":"Effects of estrogens on the testis of transsexuals: a pathological and immunocytochemical study","volume":"411","author":"Sapino","year":"1987","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0055","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1111\/jsm.13022","article-title":"Testicular functions and clinical characterization of patients with gender dysphoria (GD) undergoing sex reassignment surgery (SRS)","volume":"12","author":"Schneider","year":"2015","journal-title":"J Sex Med"},{"key":"10.1016\/j.humpath.2018.03.007_bb0060","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/j.1939-4640.1985.tb00830.x","article-title":"Testicular size: the effects of aging, malnutrition, and illness","volume":"6","author":"Handelsman","year":"1985","journal-title":"J Androl"},{"key":"10.1016\/j.humpath.2018.03.007_bb0065","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00129039-200303000-00007","article-title":"Morphometrical quantification of spermatogonial germ cells with the 57B anti-MAGE-A4 antibody in the evaluation of testicular biopsies for azoospermia","volume":"11","author":"Yakirevich","year":"2003","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0070","doi-asserted-by":"crossref","DOI":"10.1097\/PAI.0000000000000567","article-title":"INSL3 expression in Leydig cell hyperplasia and Leydig cell tumors","author":"Lakis","year":"2017","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0075","series-title":"How many adults indentify as transgender in the United States? The Williams Institute","author":"Flores","year":"2016"},{"key":"10.1016\/j.humpath.2018.03.007_bb0080","series-title":"How many people are lesbian, gay, bisexual, and transgender? The Williams Institute","author":"Gates","year":"2011"},{"key":"10.1016\/j.humpath.2018.03.007_bb0085","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1002\/phar.1487","article-title":"Gonadal suppressive and cross-sex hormone therapy for gender dysphoria in adolescents and adults","volume":"34","author":"Smith","year":"2014","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.humpath.2018.03.007_bb0090","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/00004583-200104000-00017","article-title":"Adolescents with gender identity disorder who were accepted or rejected for sex reassignment surgery: a prospective follow-up study","volume":"40","author":"Smith","year":"2001","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.humpath.2018.03.007_bb0095","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/bjd.14486","article-title":"Interventions for hirsutism excluding laser and photoepilation therapy alone: abridged Cochrane systematic review including GRADE assessments","volume":"175","author":"van Zuuren","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0100","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1095\/biolreprod.104.039404","article-title":"Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis","volume":"73","author":"Liu","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.humpath.2018.03.007_bb0105","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/humrep\/deg273","article-title":"Human \u2018testicular dysgenesis syndrome\u2019: a possible model using in-utero exposure of the rat to dibutyl phthalate","volume":"18","author":"Fisher","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.humpath.2018.03.007_bb0110","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1097\/PAS.0b013e318030979a","article-title":"Bilateral prepubertal testicular biopsies predict significance of cryptorchidism-associated mixed testicular atrophy, and allow assessment of fertility","volume":"31","author":"Nistal","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0115","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2350\/12-09-1255-PB.1","article-title":"Perspectives in pediatric pathology, chapter 3. Testicular development from birth to puberty: systematic evaluation of the prepubertal testis","volume":"18","author":"Nistal","year":"2015","journal-title":"Pediatr Dev Pathol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0120","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jri.2017.10.043","article-title":"Characterization of myeloid cell populations in human testes collected after sex reassignment surgery","volume":"125","author":"Ponte","year":"2018","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.humpath.2018.03.007_bb0125","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1089\/lgbt.2016.0153","article-title":"Parenting intentions among transgender individuals","volume":"4","author":"Tornello","year":"2017","journal-title":"LGBT Health"},{"key":"10.1016\/j.humpath.2018.03.007_bb0130","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1210\/en.2008-0674","article-title":"Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception","volume":"150","author":"Jones","year":"2009","journal-title":"Endocrinology"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817718300844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817718300844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T07:24:09Z","timestamp":1535009049000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817718300844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":26,"alternative-id":["S0046817718300844"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2018.03.007","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spectrum of findings in orchiectomy specimens of persons undergoing gender confirmation surgery","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2018.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}