{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:56:03Z","timestamp":1780916163765,"version":"3.54.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.humpath.2020.03.012","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T10:55:32Z","timestamp":1585738532000},"page":"107-115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Fibrous histiocytoma\/dermatofibroma in children: the same as adults?"],"prefix":"10.1016","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4983-3498","authenticated-orcid":false,"given":"Lara","family":"Berklite","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarangarajan","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivy","family":"John","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3718-6422","authenticated-orcid":false,"given":"Jennifer","family":"Picarsic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Santoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Alaggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2020.03.012_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2350\/11-03-1001-PB.1","article-title":"Fibrohistiocytic tumors and related neoplasms in children and adolescents","volume":"15","author":"Black","year":"2012","journal-title":"Pediatr Dev Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1590\/abd1806-4841.20132647","article-title":"Congenital multiple clustered dermatofibroma and multiple eruptive dermatofibromas--unusual presentations of a common entity","volume":"88","author":"Pinto-Almeida","year":"2013","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib3","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1365-4632.2008.03575.x","article-title":"Multiple eruptive dermatofibromas and immunosuppression: report of two cases and review of the literature","volume":"47","author":"Zaccaria","year":"2008","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1525-1470.2011.01681.x","article-title":"Congenital multiple clustered dermatofibroma in a 12-year-old girl","volume":"31","author":"Finch","year":"2014","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib5","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.1111\/j.1600-0560.2009.01325.x","article-title":"Multiple clustered dermatofibroma: case report and review of the literature","volume":"37","author":"Gershtenson","year":"2010","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1365-2559.1995.tb00193.x","article-title":"Aneurysmal benign fibrous histiocytoma: clinicopathological analysis of 40 cases of a tumour frequently misdiagnosed as a vascular neoplasm","volume":"26","author":"Calonje","year":"1995","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2020.03.012_bib7","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/00000478-199407000-00002","article-title":"Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence","volume":"18","author":"Calonje","year":"1994","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/00000372-200004000-00007","article-title":"Lipidized fibrous histiocytoma: clinicopathologic analysis of 22 cases","volume":"22","author":"Iwata","year":"2000","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00000478-200201000-00004","article-title":"Atypical fibrous histiocytoma of the skin: clinicopathologic analysis of 59 cases with evidence of infrequent metastasis","volume":"26","author":"Kaddu","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib10","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1365-2133.1989.tb07782.x","article-title":"Epithelioid cell histiocytoma: a new entity","volume":"120","author":"Jones","year":"1989","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib11","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/j.1600-0560.1996.tb01450.x","article-title":"Dermatofibroma with granular cells","volume":"23","author":"Val-Bernal","year":"1996","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib12","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1046\/j.1365-2559.1999.00633.x","article-title":"Myxoid dermatofibroma","volume":"34","author":"Zelger","year":"1999","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2020.03.012_bib13","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00000372-199210000-00004","article-title":"Dermatofibroma with osteoclast-like giant cells","volume":"14","author":"Kutchemeshgi","year":"1992","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/cup.13068","article-title":"\u201cChondroblastoma-like\u201d epithelioid fibrous histiocytoma: a previously undescribed and potentially confusing variant","volume":"45","author":"Martinez","year":"2018","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib15","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/PAS.0b013e31827070d4","article-title":"Metastasizing \u201cbenign\u201d cutaneous fibrous histiocytoma","volume":"37","author":"Doyle","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib16","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1097\/DAD.0b013e318299f28c","article-title":"Fatal case of metastatic cellular fibrous histiocytoma: case report and review of literature","volume":"36","author":"Lodewick","year":"2014","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib17","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.biocel.2014.03.027","article-title":"Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma","volume":"53","author":"P\u0142aszczyca","year":"2014","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.humpath.2020.03.012_bib18","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1111\/bjd.13548","article-title":"Epithelioid cell histiocytoma of the skin with clonal ALK gene rearrangement resulting in VCL-ALK and SQSTM1-ALK gene fusions","volume":"172","author":"Jedrych","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0560.1992.tb01348.x","article-title":"Dermatomyofibroma. A benign cutaneous, plaque-like proliferation of fibroblasts and myofibroblasts in young adults","volume":"19","author":"Kamino","year":"1992","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib20","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/DAD.0b013e3181914e6f","article-title":"Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm","volume":"31","author":"Mentzel","year":"2009","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib21","series-title":"WHO classification of skin tumours","year":"2018"},{"key":"10.1016\/j.humpath.2020.03.012_bib22","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/modpathol.2012.157","article-title":"Malignant dermatofibroma: clinicopathological, immunohistochemical and molecular analysis of seven cases","volume":"26","author":"Mentzel","year":"2013","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib23","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1525-1470.2006.00318.x","article-title":"Aneurysmal fibrous histiocytoma in a 10-year-old girl with leukemia","volume":"23","author":"Yamamoto","year":"2006","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib24","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1136\/jcp.49.4.313","article-title":"Aneurysmal and haemangiopericytoma-like fibrous histiocytoma","volume":"49","author":"Zelger","year":"1996","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib25","doi-asserted-by":"crossref","first-page":"185","DOI":"10.5021\/ad.2011.23.2.185","article-title":"A clinical and histopathological study of 122 cases of dermatofibroma (benign fibrous histiocytoma)","volume":"23","author":"Han","year":"2011","journal-title":"Ann Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib26","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/j.1365-2133.2005.06773.x","article-title":"A case of multiple aneurysmal fibrous histiocytomas","volume":"153","author":"Ichikawa","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib27","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ymgme.2016.11.007","article-title":"Mucopolysaccharidosis IVA and glycosaminoglycans","volume":"120","author":"Khan","year":"2017","journal-title":"Mol Genet Metabol"},{"key":"10.1016\/j.humpath.2020.03.012_bib28","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000478923","article-title":"Cholesterotic fibrous histiocytoma in a patient with metabolic syndrome","volume":"9","author":"Deguchi","year":"2017","journal-title":"Case Rep Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib29","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1001\/archderm.1990.01670280090016","article-title":"Cholesterotic fibrous histiocytoma. Its association with hyperlipoproteinemia","volume":"126","author":"Hunt","year":"1990","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.humpath.2020.03.012_bib30","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/pbc.24639","article-title":"Trends in incidence of primary cutaneous malignancies in children, adolescents, and young adults: a population-based study","volume":"61","author":"Senerchia","year":"2014","journal-title":"Pediatr Blood Canc"},{"key":"10.1016\/j.humpath.2020.03.012_bib31","first-page":"403","article-title":"Molecular mapping of Factor XIIIa-enriched dendrocytes in the skin (Review)","volume":"22","author":"Quatresooz","year":"2008","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.humpath.2020.03.012_bib32","first-page":"3","article-title":"Histiocytic disorders","author":"Picarsic","year":"2017"},{"key":"10.1016\/j.humpath.2020.03.012_bib33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-2559.1994.tb01290.x","article-title":"Epithelioid benign fibrous histiocytoma of skin: clinico-pathological analysis of 20 cases of a poorly known variant","volume":"24","author":"Singh Gomez","year":"1994","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2020.03.012_bib34","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1600-0560.2011.01747.x","article-title":"EMA positivity in epithelioid fibrous histiocytoma: a potential diagnostic pitfall","volume":"38","author":"Doyle","year":"2011","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.humpath.2020.03.012_bib35","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1038\/s41591-019-0653-6","article-title":"Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms","volume":"25","author":"Durham","year":"2019","journal-title":"Nat Med"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817720300617?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817720300617?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T16:37:11Z","timestamp":1758645431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817720300617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":35,"alternative-id":["S0046817720300617"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2020.03.012","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fibrous histiocytoma\/dermatofibroma in children: the same as adults?","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2020.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}