{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:33:54Z","timestamp":1793144034743,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.humpath.2022.04.006","type":"journal-article","created":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T10:47:01Z","timestamp":1649501221000},"page":"97-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"special_numbering":"C","title":["TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma"],"prefix":"10.1016","volume":"125","author":[{"given":"Esther C.","family":"Yoon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryce","family":"Parkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Salisbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance T.","family":"Albarracin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Resetkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lavinia P.","family":"Middleton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savitri","family":"Krishnamurthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxia","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiansheng","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil V.","family":"Parwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysegul A.","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaibo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.humpath.2022.04.006_bib1","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/modpathol.2012.244","article-title":"Comparison of basal-like triple-negative breast cancer defined by morphology, immunohistochemistry and transcriptional profiles","volume":"26","author":"Gazinska","year":"2013","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib2","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1158\/2159-8290.CD-18-1177","article-title":"Insights into molecular classifications of triple-negative breast cancer: improving patient selection for treatment","volume":"9","author":"Garrido-Castro","year":"2019","journal-title":"Cancer Discov"},{"key":"10.1016\/j.humpath.2022.04.006_bib3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/PAI.0000000000000186","article-title":"The novel marker GATA3 is significantly more sensitive than traditional markers mammaglobin and GCDFP15 for identifying breast cancer in surgical and cytology specimens of metastatic and matched primary tumors","volume":"24","author":"Sangoi","year":"2016","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2022.04.006_bib4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/PAI.0000000000000237","article-title":"Comparative sensitivities and specificities of antibodies to breast markers GCDFP-15, mammaglobin A, and different clones of antibodies to GATA-3: a study of 338 tumors using whole sections","volume":"24","author":"Kandalaft","year":"2016","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2022.04.006_bib5","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.cell.2006.09.048","article-title":"GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland","volume":"127","author":"Kouros-Mehr","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.humpath.2022.04.006_bib6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/ncb1530","article-title":"Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation","volume":"9","author":"Asselin-Labat","year":"2007","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.humpath.2022.04.006_bib7","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/PAS.0b013e3182a0218f","article-title":"GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors","volume":"38","author":"Miettinen","year":"2014","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib8","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/j.humpath.2012.11.003","article-title":"GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas","volume":"44","author":"Cimino-Mathews","year":"2013","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib9","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/his.12645","article-title":"GATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistry","volume":"67","author":"Huo","year":"2015","journal-title":"Histopathology"},{"key":"10.1016\/j.humpath.2022.04.006_bib10","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.anndiagpath.2014.12.001","article-title":"GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin","volume":"19","author":"Wendroth","year":"2015","journal-title":"Ann Diagn Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib11","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1136\/jclinpath-2016-204137","article-title":"Characterisation of GATA3 expression in invasive breast cancer: differences in histological subtypes and immunohistochemically defined molecular subtypes","volume":"70","author":"Tang","year":"2017","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib12","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/s41379-020-00692-8","article-title":"TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer","volume":"34","author":"Ai","year":"2021","journal-title":"Mod Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib13","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/PAS.0000000000001824","article-title":"TRPS1 expression in breast carcinomas: focusing on metaplastic breast carcinomas","volume":"46","author":"Parkinson","year":"2022","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib14","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1093\/annonc\/mdt190","article-title":"Prognostic value of the trichorhinophalangeal syndrome-1 (TRPS-1), a GATA family transcription factor, in early-stage breast cancer","volume":"24","author":"Chen","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1016\/j.humpath.2022.04.006_bib15","doi-asserted-by":"crossref","first-page":"34750","DOI":"10.18632\/oncotarget.16160","article-title":"GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancie","volume":"8","author":"Lin","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.humpath.2022.04.006_bib16","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1101\/gad.331371.119","article-title":"TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth\/differentiation and breast cancer development","volume":"34","author":"Cornelissen","year":"2020","journal-title":"Genes Dev"},{"key":"10.1016\/j.humpath.2022.04.006_bib17","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/PAI.0b013e318279bc0a","article-title":"SOX10 expression in malignant melanoma, carcinoma, and normal tissues","volume":"21","author":"Mohamed","year":"2013","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1016\/j.humpath.2022.04.006_bib18","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/PAP.0b013e318297a9d0","article-title":"Value of SOX10 immunostaining in tumor diagnosis","volume":"20","author":"Ord\u00f3\u00f1ez","year":"2013","journal-title":"Adv Anat Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib19","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/PAS.0000000000000398","article-title":"Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors","volume":"39","author":"Miettinen","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib20","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1097\/PAS.0b013e3181658c14","article-title":"Sox10: a pan-schwannian and melanocytic marker","volume":"32","author":"Nonaka","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib21","doi-asserted-by":"crossref","first-page":"152801","DOI":"10.1016\/j.prp.2019.152801","article-title":"Combined use of SOX10 and GATA3 in mammary carcinoma","volume":"216","author":"Qazi","year":"2020","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.humpath.2022.04.006_bib22","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.humpath.2012.09.005","article-title":"Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas","volume":"44","author":"Cimino-Mathews","year":"2013","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib23","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.humpath.2020.06.004","article-title":"High\u00a0frequency of p16 and SOX10 coexpression but not androgen\u00a0receptor expression in triple-negative breast cancers","volume":"102","author":"Yoon","year":"2020","journal-title":"Hum Pathol"},{"key":"10.1016\/j.humpath.2022.04.006_bib24","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10549-020-05818-9","article-title":"Combined SOX10 GATA3 is most sensitive in detecting primary and metastatic breast cancers: a comparative study of breast markers in multiple tumors","volume":"184","author":"Aphivatanasiri","year":"2020","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.humpath.2022.04.006_bib25","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.5858\/arpa.2018-0902-SA","article-title":"Human epidermal growth factor receptor 2 testing in breast cancer: American society of clinical oncology\/college of American pathologists clinical practice guideline focused update","volume":"142","author":"Wolff","year":"2018","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.humpath.2022.04.006_bib26","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1200\/JCO.19.02309","article-title":"Estrogen and progesterone receptor testing in breast cancer: ASCO\/CAP guideline update","volume":"38","author":"Allison","year":"2020","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.humpath.2022.04.006_bib27","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/his.14118","article-title":"Sry-related high-mobility-group\/HMG box 10 (SOX10) as a sensitive marker for triple-negative breast cancer","volume":"77","author":"Jamidi","year":"2020","journal-title":"Histopathology"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817722000855?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817722000855?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T16:40:15Z","timestamp":1758645615000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817722000855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":27,"alternative-id":["S0046817722000855"],"URL":"https:\/\/doi.org\/10.1016\/j.humpath.2022.04.006","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma","name":"articletitle","label":"Article Title"},{"value":"Human Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.humpath.2022.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}