{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T19:56:50Z","timestamp":1792958210969,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32470507"],"award-info":[{"award-number":["32470507"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31761133021"],"award-info":[{"award-number":["31761133021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004480","name":"Natural Science Foundation of Shanxi Province","doi-asserted-by":"publisher","award":["202403021211033"],"award-info":[{"award-number":["202403021211033"]}],"id":[{"id":"10.13039\/501100004480","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFE0196200"],"award-info":[{"award-number":["2022YFE0196200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016073","name":"Key Technologies Research and Development Program of Anhui Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016073","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Insect Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.ibmb.2025.104314","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T19:25:59Z","timestamp":1745436359000},"page":"104314","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The pore canal protein snsl is required for cuticular lipids transport and cuticle barrier function in the migratory locust, Locusta migratoria"],"prefix":"10.1016","volume":"181","author":[{"given":"Weimin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2854-9500","authenticated-orcid":false,"given":"Bernard","family":"Moussian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ibmb.2025.104314_bib1","doi-asserted-by":"crossref","first-page":"9268","DOI":"10.1073\/pnas.1608295113","article-title":"Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae","volume":"113","author":"Balabanidou","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibmb.2025.104314_bib2","article-title":"Mosquitoes cloak their legs to resist insecticides","volume":"286","author":"Balabanidou","year":"2019","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.ibmb.2025.104314_bib3","series-title":"Chemistry, Biochemistry, and Physiology of Insect Cuticular Lipids","author":"Blomquist","year":"1987"},{"key":"10.1016\/j.ibmb.2025.104314_bib5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jchromb.2013.08.023","article-title":"The use of chromatographic techniques for the separation and the identification of insect lipids","volume":"937","author":"Cerkowniak","year":"2013","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.ibmb.2025.104314_bib6","series-title":"The Insects: Structure and Function","author":"Chapman","year":"2013"},{"key":"10.1016\/j.ibmb.2025.104314_bib8","first-page":"848","article-title":"Pore canals of the insect cuticle","volume":"71","author":"Dennell","year":"1943","journal-title":"Nature"},{"key":"10.1016\/j.ibmb.2025.104314_bib10","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/icb\/38.3.471","article-title":"Water-proofing properties of cuticular lipids","volume":"38","author":"Gibbs","year":"1998","journal-title":"Am. Zool."},{"key":"10.1016\/j.ibmb.2025.104314_bib11","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jinsphys.2011.05.003","article-title":"Thermodynamics of cuticular transpiration","volume":"57","author":"Gibbs","year":"2011","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.ibmb.2025.104314_bib12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nature05382","article-title":"Specialized hepatocyte-like cells regulate Drosophila lipid metabolism","volume":"445","author":"Gutierrez","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.ibmb.2025.104314_bib13","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.ento.50.071803.130359","article-title":"Ecological, behavioral, and biochemical aspects of insect hydrocarbons","volume":"50","author":"Howard","year":"2005","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.ibmb.2025.104314_bib14","series-title":"Physiological Systems in Insects","author":"Klowden","year":"2013"},{"key":"10.1016\/j.ibmb.2025.104314_bib15","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1007\/s11427-020-1857-7","article-title":"Three-dimensional reconstruction of pore canals in the cuticle of the brown planthopper","volume":"64","author":"Li","year":"2021","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.ibmb.2025.104314_bib16","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.chemosphere.2018.05.179","article-title":"Comparisons of microsomal cytochrome P450 content and enzymatic activity towards selected model substrates and insecticides in different tissues from the migratory locust (Locusta migratoria)","volume":"208","author":"Liu","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.ibmb.2025.104314_bib17","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jip.2009.03.002","article-title":"Histopathological changes of Ceroplastes japonicus infected by Lecanicillium lecanii","volume":"101","author":"Liu","year":"2009","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.ibmb.2025.104314_bib18","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1083\/jcb.10.4.589","article-title":"Pore canals and related structures in insect cuticle","volume":"10","author":"Locke","year":"1961","journal-title":"J. Biophys. Biochem. Cytol."},{"key":"10.1016\/j.ibmb.2025.104314_bib19","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0022-1910(00)00123-2","article-title":"The Wigglesworth Lecture: insects for studying fundamental problems in biology","volume":"47","author":"Locke","year":"2001","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.ibmb.2025.104314_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1329843","article-title":"A life-and-death struggle: interaction of insects with entomopathogenic fungi across various infection stages","volume":"14","author":"Ma","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ibmb.2025.104314_bib21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev-ento-011613-162056","article-title":"The development and functions of oenocytes","volume":"59","author":"Makki","year":"2014","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.ibmb.2025.104314_bib22","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ibmb.2010.03.003","article-title":"Recent advances in understanding mechanisms of insect cuticle differentiation","volume":"40","author":"Moussian","year":"2010","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib23","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cbpc.2004.04.013","article-title":"Cuticular lipids and desiccation resistance in overwintering larvae of the goldenrod gall fly, Eurosta solidaginis (Diptera: tephritidae)","volume":"138","author":"Nelson","year":"2004","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cois.2016.05.004","article-title":"Cuticle formation and pigmentation in beetles","volume":"17","author":"Noh","year":"2016","journal-title":"Curr Opin Insect Sci"},{"key":"10.1016\/j.ibmb.2025.104314_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2019.103203","article-title":"BgFas1: a fatty acid synthase gene required for both hydrocarbon and cuticular fatty acid biosynthesis in the German cockroach, Blattella germanica (L.)","volume":"112","author":"Pei","year":"2019","journal-title":"Insect Biochem. Mol. Biol."},{"issue":"37","key":"10.1016\/j.ibmb.2025.104314_bib49","doi-asserted-by":"crossref","first-page":"14858","DOI":"10.1073\/pnas.1208650109","volume":"109","author":"Qiu","year":"2012","journal-title":"Feyereisen R.Proc Natl Acad Sci U S A."},{"key":"10.1016\/j.ibmb.2025.104314_bib26","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/icb\/38.2.382","article-title":"Sites of synthesis and transport pathways of insect hydrocarbons: cuticle and ovary as target tissues","volume":"38","author":"Schal","year":"1998","journal-title":"Am. Zool."},{"key":"10.1016\/j.ibmb.2025.104314_bib27","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1038\/ncomms3957","article-title":"The locust genome provides insight into swarm formation and long-distance flight","volume":"5","author":"Wang","year":"2014","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.ibmb.2025.104314_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008363","article-title":"Dysfunction of Oskyddad causes Harlequin-type ichthyosis-like defects in Drosophila melanogaster","volume":"16","author":"Wang","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ibmb.2025.104314_bib29","first-page":"1396","article-title":"Double cuticle barrier in two global pests, the whiteflyTrialeurodes vaporariorumand the bedbugCimex lectularius","volume":"220","author":"Wang","year":"2017","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib30","article-title":"Regionalization of surface lipids in insects","volume":"283","author":"Wang","year":"2016","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.ibmb.2025.104314_bib31","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1194\/jlr.M060368","article-title":"Flexible origin of hydrocarbon\/pheromone precursors in Drosophila melanogaster","volume":"56","author":"Wicker-Thomas","year":"2015","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.ibmb.2025.104314_bib32","first-page":"269","volume":"vol. 76","author":"Wigglesworth","year":"1933"},{"key":"10.1016\/j.ibmb.2025.104314_bib33","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1017\/S0007485300026493","article-title":"Some notes on the integument of insects in relation to the entry of contact insecticides","volume":"33","author":"Wigglesworth","year":"1942","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.ibmb.2025.104314_bib34","first-page":"459","volume":"vol. 19","author":"Wigglesworth","year":"1975"},{"key":"10.1016\/j.ibmb.2025.104314_bib35","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0040-8166(85)90092-8","article-title":"The transfer of lipid in insects from the epidermal cells of the cuticle","volume":"17","author":"Wigglesworth","year":"1985","journal-title":"Tissue Cell"},{"key":"10.1016\/j.ibmb.2025.104314_bib36","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1002\/ps.5914","article-title":"Both LmCYP4G genes function in decreasing cuticular penetration of insecticides in Locusta migratoria","volume":"76","author":"Wu","year":"2020","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ibmb.2025.104314_bib37","article-title":"Selection and assessment of reference genes for quantitative PCR normalization in migratory locust Locusta migratoria (Orthoptera: Acrididae)","volume":"9","author":"Yang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ibmb.2025.104314_bib38","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/imb.12665","article-title":"Two fatty acid synthase genes from the integument contribute to cuticular hydrocarbon biosynthesis and cuticle permeability in Locusta migratoria","volume":"29","author":"Yang","year":"2020","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib39","doi-asserted-by":"crossref","first-page":"24352","DOI":"10.1074\/jbc.M116.720581","article-title":"Helicoidal organization of chitin in the cuticle of the migratory locust requires the function of the chitin Deacetylase2 enzyme (LmCDA2)","volume":"291","author":"Yu","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibmb.2025.104314_bib40","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ibmb.2017.06.005","article-title":"The ABC transporter ABCH-9C is needed for cuticle barrier construction in Locusta migratoria","volume":"87","author":"Yu","year":"2017","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib41","article-title":"LmCYP4G102: an oenocyte-specific cytochrome P450 gene required for cuticular waterproofing in the migratory locust, Locusta migratoria","volume":"6","author":"Yu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ibmb.2025.104314_bib42","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.chemosphere.2017.08.157","article-title":"Knockdown of NADPH-cytochrome P450 reductase increases the susceptibility to carbaryl in the migratory locust, Locusta migratoria","volume":"188","author":"Zhang","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.ibmb.2025.104314_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2019.103206","article-title":"The wing-specific cuticular protein LmACP7 is essential for normal wing morphogenesis in the migratory locust","volume":"112","author":"Zhao","year":"2019","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ibmb.2025.104314_bib44","article-title":"Identification and expression of cuticular protein genes based on Locusta migratoria transcriptome","volume":"7","author":"Zhao","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ibmb.2025.104314_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinsphys.2020.104052","article-title":"The fatty acid elongase gene LmELO7 is required for hydrocarbon biosynthesis and cuticle permeability in the migratory locust, Locusta migratoria","volume":"123","author":"Zhao","year":"2020","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.ibmb.2025.104314_bib47","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3389\/fphys.2020.00790","article-title":"Apolipophorin-II\/I contributes to cuticular hydrocarbon transport and cuticle barrier construction in Locusta migratoria","volume":"11","author":"Zhao","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ibmb.2025.104314_bib48","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ejcb.2017.12.003","article-title":"The ABC transporter Snu and the extracellular protein Snsl cooperate in the formation of the lipid-based inward and outward barrier in the skin of Drosophila","volume":"97","author":"Zuber","year":"2018","journal-title":"Eur. J. Cell Biol."}],"container-title":["Insect Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096517482500058X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096517482500058X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:37:06Z","timestamp":1778791026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096517482500058X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":45,"alternative-id":["S096517482500058X"],"URL":"https:\/\/doi.org\/10.1016\/j.ibmb.2025.104314","relation":{},"ISSN":["0965-1748"],"issn-type":[{"value":"0965-1748","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The pore canal protein snsl is required for cuticular lipids transport and cuticle barrier function in the migratory locust, Locusta migratoria","name":"articletitle","label":"Article Title"},{"value":"Insect Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ibmb.2025.104314","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104314"}}