{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T16:06:32Z","timestamp":1784045192490,"version":"3.55.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32400707"],"award-info":[{"award-number":["32400707"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Insect Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ibmb.2026.104617","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T15:20:28Z","timestamp":1782314428000},"page":"104617","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Worker bees preventing diapause in Bombus terrestris queens via tyrosine metabolism"],"prefix":"10.1016","volume":"193","author":[{"given":"Jiaqi","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YuFeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuyu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamin","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0848-8695","authenticated-orcid":false,"given":"Xing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ibmb.2026.104617_bib1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00265-006-0184-2","article-title":"Regulation of worker reproduction in bumblebees (Bombus terrestris): workers eavesdrop on a queen signal","volume":"60","author":"Alaux","year":"2006","journal-title":"Behav. Ecol. Sociobiol."},{"issue":"1817","key":"10.1016\/j.ibmb.2026.104617_bib2","article-title":"A conserved class of queen pheromones? Re-evaluating the evidence in bumblebees (Bombus impatiens)","volume":"282","author":"Amsalem","year":"2015","journal-title":"Proc. Biol. Sci."},{"issue":"12","key":"10.1016\/j.ibmb.2026.104617_bib3","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1111\/1365-2656.70140","article-title":"Complex effects of climatic variation on bumblebee queen fitness","volume":"94","author":"Archer","year":"2025","journal-title":"J. Anim. Ecol."},{"key":"10.1016\/j.ibmb.2026.104617_bib4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev-ento-011118-111847","article-title":"Global trends in Bumble bee health","volume":"65","author":"Cameron","year":"2020","journal-title":"Annu. Rev. Entomol."},{"issue":"5","key":"10.1016\/j.ibmb.2026.104617_bib5","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1021\/acs.jproteome.0c00776","article-title":"Hormonal regulation of reproductive diapause that occurs in the year-round mass rearing of Bombus terrestris queens","volume":"20","author":"Chen","year":"2021","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib6","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1186\/s12864-019-6314-9","article-title":"Mating precedes selective immune priming which is maintained throughout bumblebee queen diapause","volume":"20","author":"Colgan","year":"2019","journal-title":"BMC Genom."},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s12915-023-01648-5","article-title":"Costs of reproduction are present but latent in eusocial bumblebee queens","volume":"21","author":"Collins","year":"2023","journal-title":"BMC Biol."},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib8","doi-asserted-by":"crossref","first-page":"jeb244746","DOI":"10.1242\/jeb.244746","article-title":"Impacts and mechanisms of CO2 narcosis in Bumble bees: narcosis depends on dose, caste and mating status and is not induced by anoxia","volume":"226","author":"Cressman","year":"2023","journal-title":"J. Exp. Biol."},{"issue":"6","key":"10.1016\/j.ibmb.2026.104617_bib9","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1017\/S000748532100016X","article-title":"Exploiting tools for manipulating insect diapause","volume":"112","author":"Denlinger","year":"2022","journal-title":"Bull. Entomol. Res."},{"issue":"6","key":"10.1016\/j.ibmb.2026.104617_bib10","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1111\/brv.12777","article-title":"Expanding insect pollinators in the Anthropocene","volume":"96","author":"Ghisbain","year":"2021","journal-title":"Biol. Rev. Camb. Phil. Soc."},{"issue":"4","key":"10.1016\/j.ibmb.2026.104617_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.217","article-title":"Majorbio Cloud 2024: update single-cell and multiomics workflows","volume":"3","author":"Han","year":"2024","journal-title":"iMeta"},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib12","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/imb.12957","article-title":"Changes in bumblebee queen gut microbiotas during and after overwintering diapause","volume":"34","author":"Hotchkiss","year":"2025","journal-title":"Insect Mol. Biol."},{"issue":"6592","key":"10.1016\/j.ibmb.2026.104617_bib13","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1126\/science.abn9920","article-title":"Food wanting is mediated by transient activation of dopaminergic signaling in the honey bee brain","volume":"376","author":"Huang","year":"2022","journal-title":"Science"},{"issue":"19","key":"10.1016\/j.ibmb.2026.104617_bib14","doi-asserted-by":"crossref","first-page":"2929","DOI":"10.3390\/cells11192929","article-title":"Molecular regulators of embryonic diapause and cancer diapause-like State","volume":"11","author":"Hussein","year":"2022","journal-title":"Cells"},{"issue":"1953","key":"10.1016\/j.ibmb.2026.104617_bib15","article-title":"Supplemental forage ameliorates the negative impact of insecticides on bumblebees in a pollinator-dependent crop","volume":"288","author":"Ingwell","year":"2021","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.ibmb.2026.104617_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ibmb.2023.103932","article-title":"Elevated temperature affects energy metabolism and behavior of bumblebees","volume":"155","author":"Kuo","year":"2023","journal-title":"Insect Biochem. Mol. Biol."},{"issue":"30","key":"10.1016\/j.ibmb.2026.104617_bib17","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2201089119","article-title":"Reversible mitophagy drives metabolic suppression in diapausing beetles","volume":"119","author":"Lebenzon","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.ibmb.2026.104617_bib18","doi-asserted-by":"crossref","first-page":"862","DOI":"10.3390\/insects13100862","article-title":"Integrative proteomic and phosphoproteomic analyses revealed complex mechanisms underlying reproductive diapause in Bombus terrestris queens","volume":"13","author":"Liu","year":"2022","journal-title":"Insects"},{"issue":"12","key":"10.1016\/j.ibmb.2026.104617_bib19","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"issue":"4","key":"10.1016\/j.ibmb.2026.104617_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0125011","article-title":"Quantitative trait loci for light sensitivity, body weight, body size, and morphological eye parameters in the bumblebee, Bombus terrestris","volume":"10","author":"Maebe","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib21","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/s42003-020-01586-w","article-title":"Trade-offs between sperm viability and immune protein expression in honey bee queens (Apis mellifera)","volume":"4","author":"McAfee","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.ibmb.2026.104617_bib22","series-title":"Sociobiology of Communication","article-title":"Communication between hosts and social parasites","author":"Nash","year":"2008"},{"issue":"2","key":"10.1016\/j.ibmb.2026.104617_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.12","article-title":"Majorbio Cloud: a one-stop, comprehensive bioinformatic platform for multiomics analyses","volume":"1","author":"Ren","year":"2022","journal-title":"iMeta"},{"issue":"3","key":"10.1016\/j.ibmb.2026.104617_bib24","first-page":"144","article-title":"Metabolic rate suppression and maintenance of flight muscle metabolic capacity during diapause in Bumble bee (Bombus impatiens) queens","volume":"97","author":"Rondot","year":"2024","journal-title":"Ecol. Evol. Physiol."},{"issue":"4","key":"10.1016\/j.ibmb.2026.104617_bib25","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3390\/insects14040336","article-title":"Effects of low-temperature acclimation on nutrients of Bumble bee Bombus terrestris queens during prediapause and diapause","volume":"14","author":"Shi","year":"2023","journal-title":"Insects"},{"issue":"12","key":"10.1016\/j.ibmb.2026.104617_bib26","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10947","article-title":"Pollinator deficits, food consumption, and consequences for human health: a modeling Study","volume":"130","author":"Smith","year":"2022","journal-title":"Environ. Health Perspect."},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib27","doi-asserted-by":"crossref","first-page":"coaa103","DOI":"10.1093\/conphys\/coaa103","article-title":"The effect of intrinsic physiological traits on diapause survival and their underlying mechanisms in an annual bee species Bombus impatiens","volume":"8","author":"Treanore","year":"2020","journal-title":"Conserv. Physiol."},{"key":"10.1016\/j.ibmb.2026.104617_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinsphys.2023.104557","article-title":"Uncovering the role of juvenile hormone in ovary development and egg laying in Bumble bees","volume":"150","author":"Wynants","year":"2023","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.ibmb.2026.104617_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1034584","article-title":"The rate of DNA synthesis in ovaries, fat body cells, and pericardial cells of the bumblebee (Bombus terrestris) depends on the stage of ovarian maturation","volume":"14","author":"Zavodska","year":"2023","journal-title":"Front. Physiol."},{"issue":"6","key":"10.1016\/j.ibmb.2026.104617_bib30","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1007\/s13592-021-00893-3","article-title":"Males from multiple colonies improve queen mating success in the bumblebee Bombus lantschouensis (Hymenoptera: apidae)","volume":"52","author":"Zhang","year":"2021","journal-title":"Apidologie"},{"issue":"9","key":"10.1016\/j.ibmb.2026.104617_bib31","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3390\/insects15090654","article-title":"Tracking existing factors directly affecting the reproduction of bumblebees: current knowledge","volume":"15","author":"Zhao","year":"2024","journal-title":"Insects"},{"issue":"1","key":"10.1016\/j.ibmb.2026.104617_bib32","doi-asserted-by":"crossref","first-page":"5499","DOI":"10.1038\/s41467-023-41198-6","article-title":"Unexpected worker mating and colony-founding in a superorganism","volume":"14","author":"Zhuang","year":"2023","journal-title":"Nat. Commun."}],"container-title":["Insect Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0965174826001414?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0965174826001414?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:28:36Z","timestamp":1784042916000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0965174826001414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":32,"alternative-id":["S0965174826001414"],"URL":"https:\/\/doi.org\/10.1016\/j.ibmb.2026.104617","relation":{},"ISSN":["0965-1748"],"issn-type":[{"value":"0965-1748","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Worker bees preventing diapause in Bombus terrestris queens via tyrosine metabolism","name":"articletitle","label":"Article Title"},{"value":"Insect Biochemistry and Molecular Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ibmb.2026.104617","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104617"}}