{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:43:20Z","timestamp":1793731400498,"version":"4.6.1"},"reference-count":304,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/PR38038\/PFN\/20\/1528\/2020"],"award-info":[{"award-number":["BT\/PR38038\/PFN\/20\/1528\/2020"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ibroneuroreports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IBRO Neuroscience Reports"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.ibneur.2023.11.007","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T12:28:13Z","timestamp":1706012893000},"page":"373-394","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":144,"special_numbering":"C","title":["Superoxide dismutase and neurological disorders"],"prefix":"10.1016","volume":"16","author":[{"given":"Saravana Babu","family":"Chidambaram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2986-3550","authenticated-orcid":false,"given":"Nikhilesh","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhir Rama","family":"Varma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivasan","family":"Ramamurthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrasekaran","family":"Vichitra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambika","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arehally M.","family":"Mahalakshmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musthafa Mohamed","family":"Essa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ibneur.2023.11.007_bib1","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3109\/21678421.2014.959024","article-title":"Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients","volume":"15","author":"Abe","year":"2014","journal-title":"Amyotroph. Lateral Scler. Front. Degener."},{"key":"10.1016\/j.ibneur.2023.11.007_bib2","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s11010-015-2572-2","article-title":"Experimental evidence for the therapeutic potential of tempol in the treatment of acute liver injury","volume":"411","author":"Abouzied","year":"2016","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1080\/10715760400027979","article-title":"Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis","volume":"39","author":"Aguirre","year":"2005","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib4","article-title":"PCB11 Metabolite, 3,3\u2019-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD","volume":"7","author":"Alam","year":"2018","journal-title":"Antioxid. Basel Switz."},{"key":"10.1016\/j.ibneur.2023.11.007_bib5","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/jnci\/djj049","article-title":"Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir","volume":"98","author":"Alexandre","year":"2006","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.ibneur.2023.11.007_bib6","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00210-016-1234-6","article-title":"Tempol and perindopril protect against lipopolysaccharide-induced cognition impairment and amyloidogenesis by modulating brain-derived neurotropic factor, neuroinflammation and oxido-nitrosative stress","volume":"389","author":"Ali","year":"2016","journal-title":"Naunyn. Schmiede Arch. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib7","unstructured":"Al-Muhammadi, M., Al-Tameemi, K., Kadhim, H., 2015. Role of Superoxide Dismutase Enzyme in Patients with Epilepsy 12, 1015\u20131019."},{"key":"10.1016\/j.ibneur.2023.11.007_bib8","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1093\/jexbot\/53.372.1331","article-title":"Role of superoxide dismutases (SODs) in controlling oxidative stress in plants","volume":"53","author":"Alscher","year":"2002","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.ibneur.2023.11.007_bib9","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1006\/exnr.2000.7525","article-title":"Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP","volume":"167","author":"Andreassen","year":"2001","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.jpsychires.2006.07.013","article-title":"Serum S100B and antioxidant enzymes in bipolar patients","volume":"41","author":"Andreazza","year":"2007","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib11","unstructured":"Arkansas Children\u2019s Hospital Research Institute, 2016. Treating Oxidative Stress and the Metabolic Pathology of Autism (Clinical trial registration No. NCT00572741). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib12","first-page":"609","article-title":"Mangafodipir (MnDPDP)-and MnCl2-induced endothelium-dependent relaxation in bovine mesenteric arteries","volume":"271","author":"Asplund","year":"1994","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib13","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pbb.2013.08.006","article-title":"Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins","volume":"111","author":"Atanasova","year":"2013","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ibneur.2023.11.007_bib14","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/ana.23817","article-title":"Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease","volume":"73","author":"Ayton","year":"2013","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3390\/antiox7020025","article-title":"A Review of the Catalytic Mechanism of Human Manganese Superoxide Dismutase","volume":"7","author":"Azadmanesh","year":"2018","journal-title":"Antioxidants"},{"key":"10.1016\/j.ibneur.2023.11.007_bib16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijdevneu.2010.08.001","article-title":"Post\u2010ischemic administration of nimodipine following focal cerebral ischemic\u2010reperfusion injury in rats alleviated excitotoxicity, neurobehavioural alterations and partially the bioenergetics","volume":"29","author":"Babu","year":"2011","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijdevneu.2010.08.001","article-title":"Post\u2010ischemic administration of nimodipine following focal cerebral ischemic\u2010reperfusion injury in rats alleviated excitotoxicity, neurobehavioural alterations and partially the bioenergetics","volume":"29","author":"Babu","year":"2011","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib18","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1007\/s12031-018-1165-4","article-title":"Serum Oxidative Stress Marker Levels in Unmedicated and Medicated Patients with Schizophrenia","volume":"66","author":"Bai","year":"2018","journal-title":"J. Mol. Neurosci. MN"},{"key":"10.1016\/j.ibneur.2023.11.007_bib19","first-page":"CC04","article-title":"Oxidative Stress and Major Depression","volume":"8","author":"Bajpai","year":"2014","journal-title":"J. Clin. Diagn. Res. JCDR"},{"key":"10.1016\/j.ibneur.2023.11.007_bib20","first-page":"215","article-title":"Synthetic combined superoxide dismutase\/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury","volume":"284","author":"Baker","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib21","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.freeradbiomed.2017.07.009","article-title":"Disturbance of redox homeostasis in Down Syndrome: role of iron dysmetabolism","volume":"114","author":"Barone","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib22","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1089\/ars.2009.2876","article-title":"Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential","volume":"13","author":"Batini\u0107-Haberle","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.ibneur.2023.11.007_bib23","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1006\/bbrc.1993.1509","article-title":"Salen-manganese complexes are superoxide dismutase-mimics","volume":"192","author":"Baudry","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib24","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0168-8278(03)00325-8","article-title":"Mangafodipir prevents liver injury induced by acetaminophen in the mouse","volume":"39","author":"Bedda","year":"2003","journal-title":"J. Hepatol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib25","unstructured":"Bellone, J., 2017. The Effects of Pomegranate Polyphenols on Neuropsychological Functioning Following Ischemic Stroke (Clinical trial registration No. NCT02442804). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib26","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0197-4580(95)00066-N","article-title":"Are reactive oxygen species involved in Alzheimer\u2019s disease?","volume":"16","author":"Benzi","year":"1995","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ibneur.2023.11.007_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03891-8","article-title":"SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity","volume":"12","author":"Berdy\u0144ski","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ibneur.2023.11.007_bib28","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/9584819","article-title":"Tempol, a Superoxide Dismutase Mimetic Agent, Inhibits Superoxide Anion-Induced Inflammatory Pain in Mice","volume":"2017","author":"Bernardy","year":"2017","journal-title":"BioMed. Res. Int."},{"key":"10.1016\/j.ibneur.2023.11.007_bib29","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.psyneuen.2014.09.025","article-title":"Is depression associated with increased oxidative stress? A systematic review and meta-analysis","volume":"51","author":"Black","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.ibneur.2023.11.007_bib30","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1017\/S0033291716002828","article-title":"Oxidative stress in major depressive and anxiety disorders, and the association with antidepressant use; results from a large adult cohort","volume":"47","author":"Black","year":"2017","journal-title":"Psychol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib31","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.1365-3016.2008.00928.x","article-title":"Vitamin supplement use among children with Down syndrome and risk of leukemia: A Children\u2019s Oncology Group (COG) Study","volume":"22","author":"Blair","year":"2008","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib32","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0891-5849(00)00349-X","article-title":"Increased oxidative damage to DNA in ALS patients","volume":"29","author":"Bogdanov","year":"2000","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib33","first-page":"5032","article-title":"Potential Therapeutic Applications of MnSODs and SOD-Mimetics","volume":"24","author":"Bonetta","year":"2018","journal-title":"Chem. Weinh. Bergstr. Ger."},{"key":"10.1016\/j.ibneur.2023.11.007_bib34","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0092-8674(92)90270-M","article-title":"The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles","volume":"71","author":"Borgstahl","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.ibneur.2023.11.007_bib35","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.tins.2008.09.004","article-title":"Mutant huntingtin and mitochondrial dysfunction","volume":"31","author":"Bossy-Wetzel","year":"2008","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib36","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/0024-3205(95)00055-B","article-title":"Bioenergetic and oxidative stress in neurodegenerative diseases","volume":"56","author":"Bowling","year":"1995","journal-title":"Life Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib37","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.freeradbiomed.2008.04.006","article-title":"A manganese-superoxide dismutase\/catalase mimetic extends survival in a mouse model of human prion disease","volume":"45","author":"Brazier","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib38","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1073\/pnas.93.6.2312","article-title":"beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger","volume":"93","author":"Bruce","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib39","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1006\/bbrc.1998.0131","article-title":"Manganese dipyridoxyl diphosphate: MRI contrast agent with antioxidative and cardioprotective properties?","volume":"254","author":"Brurok","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib40","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/378776a0","article-title":"Apoptosis and increased generation of reactive oxygen species in Down\u2019s syndrome neurons in vitro","volume":"378","author":"Busciglio","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ibneur.2023.11.007_bib41","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/S0891-5849(02)00794-3","article-title":"Lipid peroxidation and protein oxidation in Alzheimer\u2019s disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress","volume":"32","author":"Butterfield","year":"2002","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113055","article-title":"Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation-stress system","volume":"261","author":"Cao","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib43","unstructured":"Carr, D., 2016. Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis (Clinical trial registration No. NCT00997438). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib44","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0921-8734(92)90032-K","article-title":"Age-related changes in antioxidant enzymes and lipid peroxidation in brains of control and transgenic mice overexpressing copper-zinc superoxide dismutase","volume":"275","author":"Ceballos-Picot","year":"1992","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib45","doi-asserted-by":"crossref","first-page":"557","DOI":"10.5798\/diclemedj.0921.2012.04.0200","article-title":"Serum paraoxonase-1 activities and malondialdehyde levels in patients with epilepsy","volume":"39","author":"\u00e7evik","year":"2012","journal-title":"Dicle Med. J. Dicle Tip. Derg."},{"key":"10.1016\/j.ibneur.2023.11.007_bib46","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1083\/jcb.107.6.2169","article-title":"Molecular immunocytochemistry of the CuZn superoxide dismutase in rat hepatocytes","volume":"107","author":"Chang","year":"1988","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib47","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.1093\/hmg\/dds178","article-title":"Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington\u2019s disease","volume":"21","author":"Chaturvedi","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ibneur.2023.11.007_bib48","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/oxfordjournals.bmb.a072625","article-title":"An introduction to free radical biochemistry","volume":"49","author":"Cheeseman","year":"1993","journal-title":"Br. Med. Bull."},{"key":"10.1016\/j.ibneur.2023.11.007_bib49","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1038\/jcbfm.2009.47","article-title":"Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion","volume":"29","author":"Chen","year":"2009","journal-title":"J. Cereb. Blood Flow. Metab. . J. Int. Soc. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.ibneur.2023.11.007_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2019.00034","article-title":"Systematic Review of Gut Microbiota and Major Depression","volume":"10","author":"Cheung","year":"2019","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib51","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ejphar.2017.03.023","article-title":"Simultaneous blockade of NMDA receptors and PARP-1 activity synergistically alleviate immunoexcitotoxicity and bioenergetics in 3-nitropropionic acid intoxicated mice: Evidences from memantine and 3-aminobenzamide interventions","volume":"803","author":"Chidambaram","year":"2017","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib52","doi-asserted-by":"crossref","first-page":"11648","DOI":"10.1074\/jbc.M414327200","article-title":"Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases","volume":"280","author":"Choi","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib53","first-page":"47","article-title":"Influence of intensive multifunctional neurorehabilitation on neuronal oxidative damage in patients with Huntington\u2019s disease","volume":"30","author":"Ciancarelli","year":"2015","journal-title":"Funct. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib54","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2174\/156720212800410885","article-title":"Evidence of redox unbalance in post-acute ischemic stroke patients","volume":"9","author":"Ciancarelli","year":"2012","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib55","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.neurobiolaging.2008.05.009","article-title":"Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase\/catalase mimetics in aged mice","volume":"31","author":"Clausen","year":"2010","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ibneur.2023.11.007_bib56","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3233\/JAD-2012-111298","article-title":"Effects of the superoxide dismutase\/catalase mimetic EUK-207 in a mouse model of Alzheimer\u2019s disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline","volume":"30","author":"Clausen","year":"2012","journal-title":"J. Alzheimers Dis. JAD"},{"key":"10.1016\/j.ibneur.2023.11.007_bib57","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/35097565","article-title":"From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS","volume":"2","author":"Cleveland","year":"2001","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib58","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S2215-0366(15)00003-6","article-title":"New perspectives on schizophrenia in later life: implications for treatment, policy, and research","volume":"2","author":"Cohen","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib59","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3390\/antiox6040085","article-title":"Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes","volume":"6","author":"Coudriet","year":"2017","journal-title":"Antioxidants"},{"key":"10.1016\/j.ibneur.2023.11.007_bib60","doi-asserted-by":"crossref","first-page":"10405","DOI":"10.1073\/pnas.89.21.10405","article-title":"Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells","volume":"89","author":"Crapo","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib61","doi-asserted-by":"crossref","first-page":"716","DOI":"10.14336\/AD.2017.1018","article-title":"Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson\u2019s Disease","volume":"9","author":"De Lazzari","year":"2018","journal-title":"Aging Dis."},{"key":"10.1016\/j.ibneur.2023.11.007_bib62","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0304-3940(98)00469-8","article-title":"Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer\u2019s disease","volume":"250","author":"De Leo","year":"1998","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ibneur.2023.11.007_bib63","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/j.1471-4159.1989.tb07264.x","article-title":"Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson\u2019s disease","volume":"52","author":"Dexter","year":"1989","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib64","doi-asserted-by":"crossref","first-page":"703","DOI":"10.2147\/NDT.S60034","article-title":"Generation of superoxide anion radicals and platelet glutathione peroxidase activity in patients with schizophrenia","volume":"10","author":"Dietrich-Muszalska","year":"2014","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.ibneur.2023.11.007_bib65","first-page":"247","article-title":". Salen-manganese complexes: combined superoxide dismutase\/catalase mimics with broad pharmacological efficacy","volume":"38","author":"Doctrow","year":"1997","journal-title":"Adv. Pharmacol. San. Diego Calif."},{"key":"10.1016\/j.ibneur.2023.11.007_bib66","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S1474-4422(07)70178-3","article-title":"Research criteria for the diagnosis of Alzheimer\u2019s disease: revising the NINCDS-ADRDA criteria","volume":"6","author":"Dubois","year":"2007","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib67","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.freeradbiomed.2020.07.032","article-title":"The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells","volume":"160","author":"El-Mahdy","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib68","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1212\/01.wnl.0000187070.35365.d7","article-title":"Tolerance of high-dose (3,000 mg\/day) coenzyme Q10 in ALS","volume":"65","author":"Ferrante","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.ibneur.2023.11.007_bib69","first-page":"3139","article-title":"Oxidative Stress in Down and Williams-Beuren Syndromes: An Overview","volume":"26","author":"Ferrari","year":"2021","journal-title":"Mol. Basel Switz."},{"key":"10.1016\/j.ibneur.2023.11.007_bib70","doi-asserted-by":"crossref","first-page":"27432","DOI":"10.1074\/jbc.M213302200","article-title":"Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion","volume":"278","author":"Ferrer-Sueta","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib71","doi-asserted-by":"crossref","first-page":"9257","DOI":"10.1074\/jbc.M115.708057","article-title":"Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE","volume":"291","author":"Filograna","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib72","first-page":"797","article-title":"Evidence for DNA damage in amyotrophic lateral sclerosis","volume":"19","author":"Fitzmaurice","year":"1996","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.ibneur.2023.11.007_bib73","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.biopsych.2013.03.018","article-title":"Meta-Analysis of Oxidative Stress in Schizophrenia","volume":"74","author":"Flatow","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib74","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.2174\/156720512803569000","article-title":"The role for oxidative stress in aberrant DNA methylation in Alzheimer\u2019s disease","volume":"9","author":"Fleming","year":"2012","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib75","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/geno.1994.1357","article-title":"Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene","volume":"22","author":"Folz","year":"1994","journal-title":"Genomics"},{"key":"10.1016\/j.ibneur.2023.11.007_bib76","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.pscychresns.2017.10.001","article-title":"A pilot study of cortical glutathione in youth with depression","volume":"270","author":"Freed","year":"2017","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.ibneur.2023.11.007_bib77","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jinorgbio.2011.12.008","article-title":"Comparative studies on manganese-based SOD mimetics, including the phosphate effect, by using global spectral analysis","volume":"109","author":"Friedel","year":"2012","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib78","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0008-6363(02)00328-0","article-title":"Extracellular superoxide dismutase and cardiovascular disease","volume":"55","author":"Fukai","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib79","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1172\/JCI2105","article-title":"Vascular expression of extracellular superoxide dismutase in atherosclerosis","volume":"101","author":"Fukai","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ibneur.2023.11.007_bib80","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1089\/ars.2011.3999","article-title":"Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases","volume":"15","author":"Fukai","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.ibneur.2023.11.007_bib81","first-page":"357","article-title":"Localization of superoxide dismutases in Alzheimer\u2019s disease and Down\u2019s syndrome neocortex and hippocampus","volume":"146","author":"Furuta","year":"1995","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib82","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s12017-014-8294-x","article-title":"Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson\u2019s disease","volume":"16","author":"Gaki","year":"2014","journal-title":"Neuromolecular Med"},{"key":"10.1016\/j.ibneur.2023.11.007_bib83","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.pnpbp.2005.11.009","article-title":"Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in schizophrenia: A study of patients treated with haloperidol or clozapine","volume":"30","author":"Gama","year":"2006","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib84","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jns.2006.03.006","article-title":"Mutational analysis of the Cu\/Zn superoxide dismutase gene in a Catalan ALS population: should all sporadic ALS cases also be screened for SOD1?","volume":"247","author":"Gamez","year":"2006","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib85","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.abb.2015.01.029","article-title":"Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates","volume":"576","author":"Garbarino","year":"2015","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.ibneur.2023.11.007_bib86","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.plaphy.2010.08.016","article-title":"Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants","volume":"48","author":"Gill","year":"2010","journal-title":"Plant Physiol. Biochem. PPB"},{"key":"10.1016\/j.ibneur.2023.11.007_bib87","doi-asserted-by":"crossref","first-page":"454","DOI":"10.2174\/1389450115666140115113734","article-title":"The role of oxidative stress in Huntington\u2019s disease: are antioxidants good therapeutic candidates?","volume":"15","author":"Gil-Mohapel","year":"2014","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.ibneur.2023.11.007_bib88","first-page":"798","article-title":"EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine","volume":"275","author":"Gonzalez","year":"1995","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib89","first-page":"798","article-title":"EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine","volume":"275","author":"Gonzalez","year":"1995","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib90","doi-asserted-by":"crossref","DOI":"10.1186\/s12888-014-0268-x","article-title":"Oxidative stress in schizophrenia: a case-control study on the effects on social cognition and neurocognition","volume":"14","author":"Gonzalez-Liencres","year":"2014","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib91","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1367-5931(00)00146-0","article-title":"Nitric oxide synthase: models and mechanisms","volume":"4","author":"Groves","year":"2000","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib92","first-page":"41","article-title":"Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with Down syndrome","volume":"49","author":"Gulesserian","year":"2001","journal-title":"J. Investig. Med. . Publ. Am. Fed. Clin. Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib93","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1365-2125.2004.02210.x","article-title":"A randomized, double-blind, placebo controlled trial of melatonin add-on therapy in epileptic children on valproate monotherapy: effect on glutathione peroxidase and glutathione reductase enzymes","volume":"58","author":"Gupta","year":"2004","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib94","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1126\/science.8209258","article-title":"Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation","volume":"264","author":"Gurney","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.ibneur.2023.11.007_bib95","doi-asserted-by":"crossref","DOI":"10.3889\/oamjms.2020.4144","article-title":"Biomarkers of Oxidative Stress in Major Depressive Disorder |","author":"Hamed","year":"2020","journal-title":"Open Access Maced. J. Med. Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib96","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.biopsych.2020.02.001","article-title":"The \u03b2-Secretase BACE1 in Alzheimer\u2019s Disease","volume":"89","author":"Hampel","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib97","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1021\/acs.chemrev.5b00407","article-title":"Superoxide Ion: Generation and Chemical Implications","volume":"116","author":"Hayyan","year":"2016","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ibneur.2023.11.007_bib98","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.cmet.2012.12.005","article-title":"Adaptive Downregulation of Mitochondrial Function in Down Syndrome","volume":"17","author":"Helguera","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.ibneur.2023.11.007_bib99","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2017.00177","article-title":"Mitochondria: A Common Target for Genetic Mutations and Environmental Toxicants in Parkinson\u2019s Disease","volume":"8","author":"Helley","year":"2017","journal-title":"Front. Genet."},{"key":"10.1016\/j.ibneur.2023.11.007_bib100","doi-asserted-by":"crossref","first-page":"R42","DOI":"10.1016\/S0960-9822(99)80004-9","article-title":"Nitric oxide","volume":"9","author":"Huang","year":"1999","journal-title":"Curr. Biol. CB"},{"key":"10.1016\/j.ibneur.2023.11.007_bib101","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1755-5949.2012.00380.x","article-title":"Neuroprotection by manganese superoxide dismutase (MnSOD) mimics: antioxidant effect and oxidative stress regulation in acute experimental stroke","volume":"18","author":"Huang","year":"2012","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib102","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.actbio.2022.03.018","article-title":"A biomimetic zeolite-based nanoenzyme contributes to neuroprotection in the neurovascular unit after ischaemic stroke via efficient removal of zinc and ROS","volume":"144","author":"Huang","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.ibneur.2023.11.007_bib103","unstructured":"Hui, C., Tadi, P., Patti, L., 2022. Ischemic Stroke, in: StatPearls. StatPearls Publishing, Treasure Island (FL)."},{"key":"10.1016\/j.ibneur.2023.11.007_bib104","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1152\/physrev.00047.2006","article-title":"Life and death: metabolic rate, membrane composition, and life span of animals","volume":"87","author":"Hulbert","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ibneur.2023.11.007_bib105","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1142\/S0192415X02000235","article-title":"Antioxidant and anticonvulsant effect of a modified formula of chaihu-longu-muli-tang","volume":"30","author":"Hung-Ming","year":"2002","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib106","doi-asserted-by":"crossref","DOI":"10.1186\/s12888-021-03604-5","article-title":"Elevated activity of superoxide dismutase in male late-life schizophrenia and its correlation with clinical symptoms and cognitive deficits","volume":"21","author":"Huo","year":"2021","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib107","article-title":"Biological effects of the superoxide radical","volume":"247","author":"I","year":"1986","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.ibneur.2023.11.007_bib108","first-page":"287","article-title":"First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid","volume":"54","author":"Ighodaro","year":"2018","journal-title":"Alex. J. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib109","doi-asserted-by":"crossref","first-page":"22805","DOI":"10.1074\/jbc.M115.659151","article-title":"Dual Role of Superoxide Dismutase 2 Induced in Activated Microglia","volume":"290","author":"Ishihara","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib110","doi-asserted-by":"crossref","first-page":"7282","DOI":"10.1080\/10408398.2021.1913400","article-title":"Superoxide dismutase: an updated review on its health benefits and industrial applications","volume":"62","author":"Islam","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.ibneur.2023.11.007_bib111","article-title":"Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets","volume":"24","author":"Izzo","year":"2018","journal-title":"Mol. Med. Camb. Mass"},{"key":"10.1016\/j.ibneur.2023.11.007_bib112","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson\u2019s disease: clinical features and diagnosis","volume":"79","author":"Jankovic","year":"2008","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib113","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1136\/jnnp-2019-322338","article-title":"Parkinson\u2019s disease: etiopathogenesis and treatment","volume":"91","author":"Jankovic","year":"2020","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib114","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0140-6736(21)01730-X","article-title":"Schizophrenia","volume":"399","author":"Jauhar","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.ibneur.2023.11.007_bib115","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00401-017-1788-5","article-title":"Parkinson\u2019s disease: experimental models and reality","volume":"135","author":"Jiang","year":"2018","journal-title":"Acta Neuropathol. (Berl. )"},{"key":"10.1016\/j.ibneur.2023.11.007_bib116","article-title":"Catalytic properties of human manganese superoxide dismutase","volume":"271","author":"Jl","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib117","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.freeradbiomed.2013.04.016","article-title":"PGC-1\u03b1, mitochondrial dysfunction, and Huntington\u2019s disease.","volume":"62","author":"Johri","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib118","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0304-3940(01)01784-0","article-title":"Synthetic superoxide dismutase\/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model","volume":"304","author":"Jung","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ibneur.2023.11.007_bib119","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0201742","article-title":"Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets","volume":"13","author":"Kalozoumi","year":"2018","journal-title":"PLOS ONE"},{"key":"10.1016\/j.ibneur.2023.11.007_bib120","unstructured":"Kalpakjian, C.Z., 2016. Oral Glutathione and Health Outcomes Among Persons With Post-Polio Syndrome (Clinical trial registration No. NCT01402570). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib121","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1593\/tlo.11277","article-title":"First clinical experience with the magnetic resonance imaging contrast agent and superoxide dismutase mimetic mangafodipir as an adjunct in cancer chemotherapy-a translational study","volume":"5","author":"Karlsson","year":"2012","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib122","doi-asserted-by":"crossref","unstructured":"Karmiloff-Smith, A., Al-Janabi, T., D\u2019Souza, H., Groet, J., Massand, E., Mok, K., Startin, C., Fisher, E., Hardy, J., Nizetic, D., Tybulewicz, V., Strydom, A., 2016. The importance of understanding individual differences in Down syndrome. F1000Research 5, F1000 Faculty Rev-389. https:\/\/doi.org\/10.12688\/f1000research.7506.1.","DOI":"10.12688\/f1000research.7506.1"},{"key":"10.1016\/j.ibneur.2023.11.007_bib123","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.biopsych.2003.12.012","article-title":"Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study","volume":"55","author":"Karry","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib124","first-page":"709","article-title":"Reactive oxygen species in plants: Their generation, signal transduction, and scavenging mechanisms","volume":"5","author":"Karuppanapandian","year":"2011","journal-title":"Aust. J. Crop Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib125","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.3390\/antiox10081256","article-title":"Oxidative Stress Markers and Antioxidant Enzymes in Children and Adolescents with Depressive Disorder and Impact of Omega-3 Fatty Acids in Randomised Clinical Trial","volume":"10","author":"Katren\u010d\u00edkov\u00e1","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.ibneur.2023.11.007_bib126","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1046\/j.1471-4159.2001.00136.x","article-title":"Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity","volume":"76","author":"Katsuki","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib127","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ejphar.2006.08.007","article-title":"TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion","volume":"548","author":"Khattab","year":"2006","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib128","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1161\/hs0302.103745","article-title":"Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia\/Reperfusion in Mice","volume":"33","author":"Kim","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.ibneur.2023.11.007_bib129","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0006-8993(99)02254-4","article-title":"Changes of hippocampal Cu\/Zn-superoxide dismutase after kainate treatment in the rat","volume":"853","author":"Kim","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib130","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3389\/fphar.2016.00532","article-title":"Tempol Ameliorates and Prevents Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain","volume":"7","author":"Kim","year":"2017","journal-title":"Front. Pharm."},{"key":"10.1016\/j.ibneur.2023.11.007_bib131","first-page":"63","article-title":"Superoxide dismutase activity and zinc and copper concentrations in Parkinson\u2019s disease","volume":"7","author":"Kocat\u00fcrk","year":"2000","journal-title":"Pathophysiol. . J. Int. Soc. Pathophysiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib132","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1749-6632.1996.tb39063.x","article-title":"Parkinson\u2019s disease and free radicals. Mechanism of neurodegeneration and neuroprotection","volume":"786","author":"Kondo","year":"1996","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib133","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5194239","article-title":"Superoxide Dismutase 1 Nanozyme for Treatment of Eye Inflammation","volume":"2016","author":"Kost","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.ibneur.2023.11.007_bib134","doi-asserted-by":"crossref","first-page":"5537","DOI":"10.1073\/pnas.89.12.5537","article-title":"Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide","volume":"89","author":"Krishna","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib135","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/j.pnpbp.2008.07.001","article-title":"Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia","volume":"32","author":"Kunz","year":"2008","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib136","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00441-017-2768-8","article-title":"The genetic architecture of mitochondrial dysfunction in Parkinson\u2019s disease","volume":"373","author":"Larsen","year":"2018","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib137","doi-asserted-by":"crossref","first-page":"233","DOI":"10.5607\/en.2016.25.5.233","article-title":"Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS","volume":"25","author":"Lee","year":"2016","journal-title":"Exp. Neurobiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib138","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.redox.2017.04.027","article-title":"CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.","volume":"12","author":"Leu","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib139","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/j.1460-2075.1985.tb02320.x","article-title":"Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu\/Zn superoxide dismutase","volume":"4","author":"Levanon","year":"1985","journal-title":"EMBO J."},{"key":"10.1016\/j.ibneur.2023.11.007_bib140","article-title":"Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP4+, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H2O)MnTnHex-2-PyP5+","volume":"9","author":"Li","year":"2020","journal-title":"Antioxid. Basel Switz."},{"key":"10.1016\/j.ibneur.2023.11.007_bib141","doi-asserted-by":"crossref","first-page":"40151","DOI":"10.1074\/jbc.M111.279711","article-title":"Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity","volume":"286","author":"Li","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib142","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.taap.2017.04.004","article-title":"Pre-clinical therapeutic development of a series of metalloporphyrins for Parkinson\u2019s disease","volume":"326","author":"Liang","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib143","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.cell.2004.09.013","article-title":"Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice","volume":"119","author":"Lin","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.ibneur.2023.11.007_bib144","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/(SICI)1098-1136(20000101)29:1<25::AID-GLIA3>3.0.CO;2-G","article-title":"Cellular distribution of superoxide dismutases in the rat CNS","volume":"29","author":"Lindenau","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.ibneur.2023.11.007_bib145","doi-asserted-by":"crossref","DOI":"10.1145\/2818302","article-title":"A Meta-Analysis of Oxidative Stress Markers in Depression","volume":"10","author":"Liu","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.ibneur.2023.11.007_bib146","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0006-8993(94)91688-8","article-title":"An immunohistochemical study of copper\/zinc superoxide dismutase and manganese superoxide dismutase following focal cerebral ischemia in the rat","volume":"644","author":"Liu","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib147","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1161\/01.ATV.18.2.157","article-title":"Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins","volume":"18","author":"Luoma","year":"1998","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib148","article-title":"Prussian Blue Nanozyme as a Pyroptosis Inhibitor Alleviates Neurodegeneration","volume":"34","author":"Ma","year":"2022","journal-title":"Adv. Mater. Deerfield Beach Fla"},{"key":"10.1016\/j.ibneur.2023.11.007_bib149","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1017\/S1461145711001532","article-title":"Peripheral oxidative damage in early-stage mood disorders: a nested population-based case-control study","volume":"15","author":"Magalh\u00e3es","year":"2012","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib150","first-page":"323","article-title":"Role of superoxide dismutases in oxidative damage and neurodegenerative disorders","volume":"8","author":"Maier","year":"2002","journal-title":"Neurosci. Rev. J. Bringing Neurobiol. Neurol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib151","doi-asserted-by":"crossref","DOI":"10.1006\/cimm.1997.1091","article-title":"Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites","author":"Malfroy","year":"1997","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib152","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijbiomac.2014.07.039","article-title":"Protective effect of chemically modified SOD on lipid peroxidation and antioxidant status in diabetic rats","volume":"72","author":"Mansuro\u011flu","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib153","doi-asserted-by":"crossref","first-page":"754","DOI":"10.2174\/1389557519666191104110908","article-title":"Parkinson\u2019s Disease: A Review from Pathophysiology to Treatment","volume":"20","author":"Marino","year":"2020","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib154","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1042\/bj2220649","article-title":"Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species","volume":"222","author":"Marklund","year":"1984","journal-title":"Biochem. J."},{"key":"10.1016\/j.ibneur.2023.11.007_bib155","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1172\/JCI111550","article-title":"Extracellular superoxide dismutase in human tissues and human cell lines","volume":"74","author":"Marklund","year":"1984","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ibneur.2023.11.007_bib156","doi-asserted-by":"crossref","first-page":"13576","DOI":"10.1073\/pnas.0902714106","article-title":"Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer\u2019s disease","volume":"106","author":"Massaad","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib157","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/ene.13413","article-title":"Huntington\u2019s disease: a clinical review","volume":"25","author":"McColgan","year":"2018","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib158","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0891-5849(88)90109-8","article-title":"Superoxide dismutase: the first twenty years (1968-1988)","volume":"5","author":"McCord","year":"1988","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib159","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146129","article-title":"Iron and Oxidative Stress in Parkinson\u2019s Disease: An Observational Study of Injury Biomarkers","volume":"11","author":"Medeiros","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.ibneur.2023.11.007_bib160","doi-asserted-by":"crossref","DOI":"10.1186\/1478-811X-11-34","article-title":"Complexity of dopamine metabolism","volume":"11","author":"Meiser","year":"2013","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.ibneur.2023.11.007_bib161","doi-asserted-by":"crossref","first-page":"8348","DOI":"10.1523\/JNEUROSCI.21-21-08348.2001","article-title":"Lifespan Extension and Rescue of Spongiform Encephalopathy in Superoxide Dismutase 2 Nullizygous Mice Treated with Superoxide Dismutase\u2013Catalase Mimetics","volume":"21","author":"Melov","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib162","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1126\/science.289.5484.1567","article-title":"Extension of life-span with superoxide dismutase\/catalase mimetics","volume":"289","author":"Melov","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ibneur.2023.11.007_bib163","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00508-015-0742-6","article-title":"Serum antioxidant enzymes activities and oxidative stress levels in patients with acute ischemic stroke: influence on neurological status and outcome","volume":"128","author":"Milanlioglu","year":"2016","journal-title":"Wien. Klin. Wochenschr."},{"key":"10.1016\/j.ibneur.2023.11.007_bib164","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.bbadis.2011.12.002","article-title":"Manganese superoxide dismutase, MnSOD and its mimics","volume":"1822","author":"Miriyala","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ibneur.2023.11.007_bib165","unstructured":"Mischley, L., 2015. Central Nervous System Uptake of Intranasal Glutathione in Parkinson\u2019s Disease (Clinical trial registration No. NCT02324426). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib166","first-page":"289","article-title":"Phase IIb Study of Intranasal Glutathione in Parkinson\u2019s Disease","volume":"7","author":"Mischley","year":"2017","journal-title":"J. Park. Dis."},{"key":"10.1016\/j.ibneur.2023.11.007_bib167","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2021.617588","article-title":"Mitochondrial Dysfunction and Oxidative Stress in Alzheimer\u2019s Disease","volume":"13","author":"Misrani","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib168","unstructured":"Mitsubishi Tanabe Pharma Corporation, 2014. A Phase IIa, Multi-centre, Randomised, Double-blind, Placebo Controlled, Clinical Study Investigating the Safety, Tolerability and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke (Clinical trial registration No. NCT00821821). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib169","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/pcn.12319","article-title":"Analysis of oxidative stress expressed by urinary level of biopyrrins and 8-hydroxydeoxyguanosine in patients with chronic schizophrenia","volume":"69","author":"Miyaoka","year":"2015","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib170","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1177\/002215549704501204","article-title":"Regional and ultrastructural immunolocalization of copper-zinc superoxide dismutase in rat central nervous system","volume":"45","author":"Moreno","year":"1997","journal-title":"J. Histochem. Cytochem. . J. Histochem. Soc."},{"key":"10.1016\/j.ibneur.2023.11.007_bib171","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.brainresbull.2022.09.021","article-title":"The effects of the superoxide dismutase mimetic, MnTMPyP, post hypoxia and oxygen glucose deprivation in isolated rat hippocampal slices","volume":"190","author":"Moreton","year":"2022","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ibneur.2023.11.007_bib172","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1523\/JNEUROSCI.18-01-00205.1998","article-title":"Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency","volume":"18","author":"Murakami","year":"1998","journal-title":"J. Neurosci. . J. Soc. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib173","doi-asserted-by":"crossref","DOI":"10.4061\/2011\/654207","article-title":"Formation of the 42-mer Amyloid \u03b2 Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer\u2019s Disease","volume":"2011","author":"Murakami","year":"2011","journal-title":"J. Amino Acids"},{"key":"10.1016\/j.ibneur.2023.11.007_bib174","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/sj.bjp.0705430","article-title":"On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies","volume":"140","author":"Muscoli","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib175","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/01.STR.32.1.184","article-title":"Gene transfer of extracellular superoxide dismutase increases superoxide dismutase activity in cerebrospinal fluid","volume":"32","author":"Nakane","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.ibneur.2023.11.007_bib176","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nm0395-226","article-title":"Overexpressing Cu\/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson\u2019s disease","volume":"1","author":"Nakao","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib177","unstructured":"NCCIH), 2006. Natural Antioxidants in the Treatment of Multiple Sclerosis (Clinical trial registration No. NCT00010842). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib178","unstructured":"NIMH), 2011. An Investigation Examining the Evidence for Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder (Clinical trial registration No. NCT00327756). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib179","unstructured":"NIA), 2009. Evaluation of the Safety, Tolerability and Impact on Biomarkers of Anti-Oxidant Treatment of Mild to Moderate Alzheimer\u2019s Disease (Clinical trial registration No. NCT00117403). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib180","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.bbi.2017.02.018","article-title":"Oral administration of the nitroxide radical TEMPOL exhibits immunomodulatory and therapeutic properties in multiple sclerosis models","volume":"62","author":"Neil","year":"2017","journal-title":"Brain. Behav. Immun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib181","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1161\/01.RES.0000149568.85071.FB","article-title":"Fibulin-5 is a novel binding protein for extracellular superoxide dismutase","volume":"95","author":"Nguyen","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib182","doi-asserted-by":"crossref","first-page":"730","DOI":"10.4161\/epi.25012","article-title":"Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults","volume":"8","author":"Niedzwiecki","year":"2013","journal-title":"Epigenetics"},{"key":"10.1016\/j.ibneur.2023.11.007_bib183","first-page":"1","article-title":"Inflammation following stroke","volume":"13","author":"Nilupul Perera","year":"2006","journal-title":"J. Clin. Neurosci. . J. Neurosurg. Soc. Austral"},{"key":"10.1016\/j.ibneur.2023.11.007_bib184","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/(SICI)1098-1136(199808)23:4<285::AID-GLIA1>3.0.CO;2-2","article-title":"Differential expression of superoxide dismutase isoforms in neuronal and glial compartments in the course of excitotoxically mediated neurodegeneration: relation to oxidative and nitrergic stress","volume":"23","author":"Noack","year":"1998","journal-title":"Glia"},{"key":"10.1016\/j.ibneur.2023.11.007_bib185","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1093\/jnen\/59.11.1011","article-title":"Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome","volume":"59","author":"Nunomura","year":"2000","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib186","unstructured":"NYU Langone Health, 2018. Turmeric as Treatment in Epilepsy (Clinical trial registration No. NCT03254680). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib187","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1006\/bbrc.1998.8186","article-title":"Early glycoxidation damage in brains from Down\u2019s syndrome","volume":"243","author":"Odetti","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib188","doi-asserted-by":"crossref","first-page":"38388","DOI":"10.1074\/jbc.M105395200","article-title":"Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria","volume":"276","author":"Okado-Matsumoto","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib189","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/00019052-199412000-00013","article-title":"Metals and free radicals in neurodegeneration","volume":"7","author":"Olanow","year":"1994","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib190","doi-asserted-by":"crossref","first-page":"639","DOI":"10.3390\/antiox8120639","article-title":"Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide","volume":"8","author":"Olson","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.ibneur.2023.11.007_bib191","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0140-6736(87)90827-0","article-title":"Raised cerebrospinal-fluid copper concentration in Parkinson\u2019s disease","author":"Pall","year":"1987","journal-title":"Lancet Lond. Engl. 2"},{"key":"10.1016\/j.ibneur.2023.11.007_bib192","first-page":"590","article-title":"The lipid peroxidation product as a marker of oxidative stress in epilepsy","volume":"6","author":"Pandey","year":"2012","journal-title":"J. Clin. Diagn. Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib193","first-page":"621","article-title":"Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer\u2019s disease","volume":"140","author":"Pappolla","year":"1992","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib194","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1073\/pnas.92.4.954","article-title":"Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons","volume":"92","author":"Pardo","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib195","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.nbd.2015.07.005","article-title":"Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy","volume":"82","author":"Pearson","year":"2015","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.ibneur.2023.11.007_bib196","doi-asserted-by":"crossref","DOI":"10.1186\/1742-2094-2-12","article-title":"Cu\/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury","volume":"2","author":"Peluffo","year":"2005","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.ibneur.2023.11.007_bib197","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1046\/j.1471-4159.2004.02363.x","article-title":"Induction of motor neuron apoptosis by free 3-nitro-L-tyrosine","volume":"89","author":"Peluffo","year":"2004","journal-title":"J. Neurochem"},{"key":"10.1016\/j.ibneur.2023.11.007_bib198","doi-asserted-by":"crossref","first-page":"29194","DOI":"10.1074\/jbc.M500984200","article-title":"Superoxide dismutase\/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease","volume":"280","author":"Peng","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib199","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/724904","article-title":"Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia","volume":"2012","author":"Perluigi","year":"2012","journal-title":"Curr. Gerontol. Geriatr. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib200","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/S0891-5849(02)01113-9","article-title":"Is oxidative damage the fundamental pathogenic mechanism of Alzheimer\u2019s and other neurodegenerative diseases?","volume":"33","author":"Perry","year":"2002","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib201","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.3233\/JAD-142391","article-title":"Plasma thiols levels in Alzheimer\u2019s disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation","volume":"44","author":"Persichilli","year":"2015","journal-title":"J. Alzheimers Dis. JAD"},{"key":"10.1016\/j.ibneur.2023.11.007_bib202","doi-asserted-by":"crossref","first-page":"13705","DOI":"10.1074\/jbc.M310217200","article-title":"Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation","volume":"279","author":"Petersen","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib203","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1093\/hmg\/dds529","article-title":"Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects","volume":"22","author":"Piccoli","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ibneur.2023.11.007_bib204","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.645646","article-title":"Lipid Transport and Metabolism at the Blood-Brain Interface: Implications in Health and Disease","volume":"12","author":"Pifferi","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib205","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1089\/089771501750291864","article-title":"Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse","volume":"18","author":"Pineda","year":"2001","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.ibneur.2023.11.007_bib206","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000337115","article-title":"Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity","volume":"21","author":"Polazzi","year":"2013","journal-title":"Neurosignals"},{"key":"10.1016\/j.ibneur.2023.11.007_bib207","doi-asserted-by":"crossref","first-page":"216","DOI":"10.2174\/156720207781387213","article-title":"The response of the aged brain to stroke: too much, too soon?","volume":"4","author":"Popa-Wagner","year":"2007","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib208","article-title":"Oxidative Stress in the Development of Genetic Generalised Epilepsy: An Observational Study in Southern Indian Population","volume":"11","author":"Prasad","year":"2017","journal-title":"J. Clin. Diagn. Res. JCDR"},{"key":"10.1016\/j.ibneur.2023.11.007_bib209","unstructured":"Priller, J., 2015. Effects of EGCG (Epigallocatechin Gallate) in Huntington\u2019s Disease The ETON-Study - A Randomized, Double-blind, Stratified, Placebo-controlled Prospective Investigator Initiated Multicenter Trial - (Clinical trial registration No. NCT01357681). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib210","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1523\/JNEUROSCI.12-05-01658.1992","article-title":"Transgenic mice with increased Cu\/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity","volume":"12","author":"Przedborski","year":"1992","journal-title":"J. Neurosci. . J. Soc. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib211","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1001\/jamaneurol.2016.2742","article-title":"Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease: A Systematic Review and Meta-analysis","volume":"73","author":"Qin","year":"2016","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib212","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0165-1781(03)00220-8","article-title":"Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients","volume":"121","author":"Ranjekar","year":"2003","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib213","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/j.freeradbiomed.2008.03.012","article-title":"Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease","volume":"44","author":"Resende","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib214","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1093\/toxsci\/kft199","article-title":"Oxidizing effects of exogenous stressors in Huntington\u2019s disease knock-in striatal cells--protective effect of cystamine and creatine","volume":"136","author":"Ribeiro","year":"2013","journal-title":"Toxicol. Sci. . J. Soc. Toxicol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib215","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1471-4159.1989.tb09150.x","article-title":"Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains","volume":"52","author":"Riederer","year":"1989","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib216","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s00415-016-8091-6","article-title":"Recent advances in amyotrophic lateral sclerosis","volume":"263","author":"Riva","year":"2016","journal-title":"J. Neurol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib217","doi-asserted-by":"crossref","first-page":"9897","DOI":"10.1073\/pnas.96.17.9897","article-title":"EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology","volume":"96","author":"Rong","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib218","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.3390\/molecules26071844","article-title":"Superoxide Dismutase Administration: A Review of Proposed Human Uses","volume":"26","author":"Rosa","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.ibneur.2023.11.007_bib219","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/362059a0","article-title":"Mutations in Cu\/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis","volume":"362","author":"Rosen","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.ibneur.2023.11.007_bib220","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1056\/NEJM200105313442207","article-title":"Amyotrophic lateral sclerosis","volume":"344","author":"Rowland","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib221","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1093\/brain\/awt097","article-title":"Is SOD1 loss of function involved in amyotrophic lateral sclerosis?","volume":"136","author":"Saccon","year":"2013","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.ibneur.2023.11.007_bib222","first-page":"886","article-title":"Superoxide, superoxide dismutase and ischemic injury","volume":"2000","author":"Salvemini","year":"2002","journal-title":"Curr. Opin. Investig. Drugs Lond. Engl."},{"key":"10.1016\/j.ibneur.2023.11.007_bib223","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1038\/sj.bjp.0703841","article-title":"Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403","volume":"132","author":"Salvemini","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib224","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1006\/pupt.2002.0374","article-title":"Superoxide Dismutase Mimetics","volume":"15","author":"Salvemini","year":"2002","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib225","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nrd796","article-title":"Sod mimetics are coming of age","volume":"1","author":"Salvemini","year":"2002","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib226","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1126\/science.286.5438.304","article-title":"A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats","volume":"286","author":"Salvemini","year":"1999","journal-title":"Science"},{"issue":"Pt 1","key":"10.1016\/j.ibneur.2023.11.007_bib227","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3109\/10715769109145785","article-title":"Nitroxide SOD-mimics: modes of action","volume":"12-13","author":"Samuni","year":"1991","journal-title":"Free Radic. Res. Commun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib228","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/S0140-6736(21)02143-7","article-title":"Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic","volume":"398","author":"Santomauro","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.ibneur.2023.11.007_bib229","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/pcn.12333","article-title":"First-episode psychosis is associated with oxidative stress: Effects of short-term antipsychotic treatment","volume":"69","author":"Sarandol","year":"2015","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib230","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1074\/jbc.RA119.011084","article-title":"Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens","volume":"295","author":"Schatzman","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib231","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jad.2015.12.020","article-title":"Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder","volume":"192","author":"Scola","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ibneur.2023.11.007_bib232","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.arr.2004.05.002","article-title":"Reactive oxygen species and synaptic plasticity in the aging hippocampus","volume":"3","author":"Serrano","year":"2004","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.ibneur.2023.11.007_bib233","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.nbd.2017.11.008","article-title":"Role of the Fyn-PKC\u03b4 signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy","volume":"110","author":"Sharma","year":"2018","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.ibneur.2023.11.007_bib234","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1042\/bj20020154","article-title":"Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase\/catalase mimetics","volume":"366","author":"Sharpe","year":"2002","journal-title":"Biochem. J."},{"key":"10.1016\/j.ibneur.2023.11.007_bib235","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1212\/WNL.53.6.1239","article-title":"Mice lacking cytosolic copper\/zinc superoxide dismutase display a distinctive motor axonopathy","volume":"53","author":"Shefner","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.ibneur.2023.11.007_bib236","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1124\/jpet.110.176701","article-title":"Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage","volume":"338","author":"Sheng","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ibneur.2023.11.007_bib237","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.freeradbiomed.2004.05.019","article-title":"Aberrant neuronal and mitochondrial proteins in hippocampus of transgenic mice overexpressing human Cu\/Zn superoxide dismutase 1","volume":"37","author":"Shin","year":"2004","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib238","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/hmg\/ddr024","article-title":"Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington\u2019s disease: implications for selective neuronal damage","volume":"20","author":"Shirendeb","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ibneur.2023.11.007_bib239","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1093\/hmg\/ddr475","article-title":"Mutant huntingtin\u2019s interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington\u2019s disease","volume":"21","author":"Shirendeb","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ibneur.2023.11.007_bib240","doi-asserted-by":"crossref","first-page":"14186","DOI":"10.1039\/C7DT03278A","article-title":"The design of synthetic superoxide dismutase mimetics: seven-coordinate water soluble manganese( ii) and iron( ii) complexes and their superoxide dismutase-like activity studies","volume":"46","author":"Singh","year":"2017","journal-title":"Dalton Trans."},{"key":"10.1016\/j.ibneur.2023.11.007_bib241","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1016\/S1734-1140(13)71517-2","article-title":"Oxidative stress markers in affective disorders","volume":"65","author":"Siwek","year":"2013","journal-title":"Pharmacol. Rep. PR"},{"key":"10.1016\/j.ibneur.2023.11.007_bib242","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/nm.2313","article-title":"Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity","volume":"17","author":"Song","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib243","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.freeradbiomed.2008.05.014","article-title":"Proteomic and oxidative stress analysis in human brain samples of Huntington disease","volume":"45","author":"Sorolla","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib244","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.freeradbiomed.2007.01.019","article-title":"Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria","volume":"42","author":"Spasojevi\u0107","year":"2007","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib245","article-title":"Lipophilicity of Mn(III) N-Alkylpyridylporphyrins Dominates Their Accumulation Within Mitochondria and Therefore in Vivo Efficacy: a Mouse Study","volume":"51","author":"Spasojevic","year":"2011","journal-title":"FREE Radic. Biol. Med. - FREE Radic. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib246","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/path.1711750202","article-title":"Nitric oxide--friend and foe","volume":"175","author":"Springall","year":"1995","journal-title":"J. Pathol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib247","unstructured":"Srikrishna, R., Suresh, D.R., 2009. Biochemical study of antioxidant profile in acute ischemic stroke."},{"key":"10.1016\/j.ibneur.2023.11.007_bib248","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2020.103917","article-title":"An insight on superoxide dismutase (SOD) from plants for mammalian health enhancement","volume":"68","author":"Stephenie","year":"2020","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.ibneur.2023.11.007_bib249","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1177\/1535370215576313","article-title":"Parkinson\u2019s disease and enhanced inflammatory response","volume":"240","author":"Stojkovska","year":"2015","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib250","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.cell.2006.09.024","article-title":"Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators","volume":"127","author":"St-Pierre","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.ibneur.2023.11.007_bib251","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1161\/01.ATV.15.11.2032","article-title":"The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase","volume":"15","author":"Str\u00e5lin","year":"1995","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib252","doi-asserted-by":"crossref","first-page":"38084","DOI":"10.1074\/jbc.M105296200","article-title":"A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage","volume":"276","author":"Sturtz","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib253","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1089\/ars.2006.8.2021","article-title":"Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer\u2019s disease: insights into mechanism of neurodegeneration from redox proteomics","volume":"8","author":"Sultana","year":"2006","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.ibneur.2023.11.007_bib254","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bbrc.2012.10.107","article-title":"Calcium leak through ryanodine receptor is involved in neuronal death induced by mutant huntingtin","volume":"429","author":"Suzuki","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ibneur.2023.11.007_bib255","article-title":"Tissue distribution of immunoreactive mouse extracellular superoxide dismutase","volume":"275","author":"T","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib256","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.pneurobio.2004.02.001","article-title":"Astrocyte apoptosis: implications for neuroprotection","volume":"72","author":"Takuma","year":"2004","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib257","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004481","article-title":"Identification and Analysis of the Role of Superoxide Dismutases Isoforms in the Pathogenesis of Paracoccidioides spp","volume":"10","author":"Tamayo","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ibneur.2023.11.007_bib258","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1165\/rcmb.2005-0212OC","article-title":"Inflammatory Cells as a Source of Airspace Extracellular Superoxide Dismutase after Pulmonary Injury","volume":"34","author":"Tan","year":"2006","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib259","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/nature20413","article-title":"Decoding ALS: from genes to mechanism","volume":"539","author":"Taylor","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.ibneur.2023.11.007_bib260","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/BF01611436","article-title":"The immunocytochemical demonstration of copper-zinc superoxide dismutase in the brain","volume":"15","author":"Thaete","year":"1986","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib261","unstructured":"Torre, R. de la, 2016. Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool (Clinical trial registration No. NCT01699711). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib262","doi-asserted-by":"crossref","first-page":"5677","DOI":"10.1021\/ic3012519","article-title":"Differential Coordination Demands in Fe versus Mn Water-Soluble Cationic Metalloporphyrins Translate into Remarkably Different Aqueous Redox Chemistry and Biology","volume":"52","author":"Tovmasyan","year":"2013","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib263","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1080\/10715760802582183","article-title":"Antioxidant properties of MitoTEMPOL and its hydroxylamine","volume":"43","author":"Trnka","year":"2009","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib264","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.psychres.2015.12.005","article-title":"Increased activities of both superoxide dismutase and catalase were indicators of acute depressive episodes in patients with major depressive disorder","volume":"235","author":"Tsai","year":"2016","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib265","doi-asserted-by":"crossref","first-page":"142ra97","DOI":"10.1126\/scitranslmed.3003799","article-title":"PGC-1\u03b1 rescues Huntington\u2019s disease proteotoxicity by preventing oxidative stress and promoting TFEB function","volume":"4","author":"Tsunemi","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib266","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1054\/mehy.2001.1327","article-title":"Increased superoxide dismutase and Down\u2019s syndrome","volume":"56","author":"Turrens","year":"2001","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.ibneur.2023.11.007_bib267","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/sj.ejcn.1602248","article-title":"Antioxidant supplementation enhances antioxidant capacity and mitigates oxidative damage following acute ischaemic stroke","volume":"59","author":"Ullegaddi","year":"2005","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.ibneur.2023.11.007_bib268","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1073\/pnas.76.9.4245","article-title":"pH-dependent migration of copper(II) to the vacant zinc-binding site of zinc-free bovine erythrocyte superoxide dismutase","volume":"76","author":"Valentine","year":"1979","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ibneur.2023.11.007_bib269","series-title":"Comparative Biology of the Normal Lung","first-page":"489","article-title":"Chapter 25 - Antioxidant Defenses in the Lung","author":"van der Vliet","year":"2015"},{"key":"10.1016\/j.ibneur.2023.11.007_bib270","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s10863-010-9320-9","article-title":"Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy?","volume":"42","author":"Waldbaum","year":"2010","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1016\/j.ibneur.2023.11.007_bib271","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/em.20586","article-title":"Mitochondrial DNA mutations in disease and aging","volume":"51","author":"Wallace","year":"2010","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.ibneur.2023.11.007_bib272","doi-asserted-by":"crossref","DOI":"10.1186\/s13024-020-00376-6","article-title":"Mitochondria dysfunction in the pathogenesis of Alzheimer\u2019s disease: recent advances","volume":"15","author":"Wang","year":"2020","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.ibneur.2023.11.007_bib273","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1016\/j.transproceed.2007.08.091","article-title":"Protective effects of MnM2Py4P and Mn-salen against small bowel ischemia\/reperfusion injury in rats using an in vivo and an ex vivo electron paramagnetic resonance technique with a spin probe","volume":"39","author":"Watanabe","year":"2007","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.ibneur.2023.11.007_bib274","doi-asserted-by":"crossref","first-page":"3582","DOI":"10.1016\/S0021-9258(19)43969-0","article-title":"Superoxide dismutase. Organelle specificity","volume":"248","author":"Weisiger","year":"1973","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib275","doi-asserted-by":"crossref","first-page":"16804","DOI":"10.1074\/jbc.R117.789271","article-title":"Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions","volume":"292","author":"Wong","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ibneur.2023.11.007_bib276","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1016\/S0042-6989(96)00210-6","article-title":"Cytochrome oxidase in Alzheimer\u2019s disease: Biochemical, histochemical, and immunohistochemical analyses of the visual and other systems","volume":"37","author":"Wong-Riley","year":"1997","journal-title":"Vis. Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib277","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.pnpbp.2013.02.015","article-title":"Free radicals, antioxidant defense systems, and schizophrenia","volume":"46","author":"Wu","year":"2013","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib278","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pnpbp.2011.08.018","article-title":"Elevated plasma superoxide dismutase in first-episode and drug naive patients with schizophrenia: inverse association with positive symptoms","volume":"36","author":"Wu","year":"2012","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib279","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3892\/mmr.2013.1790","article-title":"Regulation of Cu-Zn superoxide dismutase on SCN2A in SH-SY5Y cells as a potential therapy for temporal lobe epilepsy","volume":"9","author":"Xiang","year":"2014","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.ibneur.2023.11.007_bib280","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1161\/01.STR.25.1.165","article-title":"Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia","volume":"25","author":"Yang","year":"1994","journal-title":"Stroke"},{"key":"10.1016\/j.ibneur.2023.11.007_bib281","article-title":"Bioinspired copper single-atom nanozyme as a superoxide dismutase-like antioxidant for sepsis treatment","volume":"2","author":"Yang","year":"2022","journal-title":"Exploration"},{"key":"10.1016\/j.ibneur.2023.11.007_bib282","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.dnarep.2008.03.012","article-title":"Mitochondrial DNA Damage and Repair in Neurodegenerative Disorders","volume":"7","author":"Yang","year":"2008","journal-title":"DNA Repair"},{"key":"10.1016\/j.ibneur.2023.11.007_bib283","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2020.00053","article-title":"Contra-Directional Expression of Plasma Superoxide Dismutase with Lipoprotein Cholesterol and High-Sensitivity C-reactive Protein as Important Markers of Parkinson\u2019s Disease Severity","volume":"12","author":"Yang","year":"2020","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib284","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.plefa.2003.08.015","article-title":"Membrane polyunsaturated fatty acids and CSF cytokines in patients with schizophrenia","volume":"69","author":"Yao","year":"2003","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"key":"10.1016\/j.ibneur.2023.11.007_bib285","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0920-9964(94)90046-9","article-title":"Red blood cell membrane dynamics in schizophrenia. III. Correlation of fatty acid abnormalities with clinical measures","volume":"13","author":"Yao","year":"1994","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib286","first-page":"359","article-title":"Therapeutic potential of superoxide dismutase (SOD) for resolution of inflammation","volume":"55","author":"Yasui","year":"2006","journal-title":"Inflamm. Res. . J. Eur. Histamine Res. Soc. Al"},{"key":"10.1016\/j.ibneur.2023.11.007_bib287","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.eplepsyres.2009.02.003","article-title":"Effects of epilepsy and valproic acid on oxidant status in children with idiopathic epilepsy","volume":"84","author":"Yi\u015f","year":"2009","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib288","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.biopsych.2012.11.018","article-title":"Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia","volume":"74","author":"Yoon","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ibneur.2023.11.007_bib289","first-page":"88","article-title":"Therapeutic potentials of superoxide dismutase","volume":"12","author":"Younus","year":"2018","journal-title":"Int. J. Health Sci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib290","first-page":"641","article-title":"Plasma antioxidant status and motor features in de novo Chinese Parkinson\u2019s disease patients","volume":"126","author":"Yuan","year":"2016","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib291","unstructured":"Zahid, S., 2019. Role of Selected Antioxidants (Vitamin C and E) in the Management of Schizophrenia (Clinical trial registration No. NCT04078048). clinicaltrials.gov."},{"key":"10.1016\/j.ibneur.2023.11.007_bib292","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.neurobiolaging.2006.03.008","article-title":"Oxidative stress: a bridge between Down\u2019s syndrome and Alzheimer\u2019s disease","volume":"28","author":"Zana","year":"2007","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ibneur.2023.11.007_bib293","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0006-8993(89)91550-3","article-title":"Superoxide dismutase activity in Alzheimer\u2019s disease: possible mechanism for paired helical filament formation","volume":"476","author":"Zemlan","year":"1989","journal-title":"Brain Res"},{"key":"10.1016\/j.ibneur.2023.11.007_bib294","article-title":"Low Serum Superoxide Dismutase Is Associated With a High Risk of Cognitive Impairment After Mild Acute Ischemic Stroke","volume":"14","author":"Zhang","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.ibneur.2023.11.007_bib295","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.jpsychires.2013.03.014","article-title":"Clinical symptoms and cognitive impairment associated with male schizophrenia relate to plasma manganese superoxide dismutase activity: a case-control study","volume":"47","author":"Zhang","year":"2013","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.ibneur.2023.11.007_bib296","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1093\/schbul\/sbt045","article-title":"Cognitive function, plasma MnSOD activity, and MnSOD Ala-9Val polymorphism in patients with schizophrenia and normal controls","volume":"40","author":"Zhang","year":"2014","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.ibneur.2023.11.007_bib297","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00213-008-1447-6","article-title":"Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics","volume":"204","author":"Zhang","year":"2009","journal-title":"Psychopharmacol. (Berl. )"},{"key":"10.1016\/j.ibneur.2023.11.007_bib298","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1039\/C9RA09021E","article-title":"Nanozyme-based catalytic theranostics","volume":"10","author":"Zhang","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.ibneur.2023.11.007_bib299","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.7150\/thno.83370","article-title":"The applications of nanozymes in neurological diseases: From mechanism to design","volume":"13","author":"Zhang","year":"2023","journal-title":"Theranostics"},{"key":"10.1016\/j.ibneur.2023.11.007_bib300","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s10571-015-0274-7","article-title":"Intrathecal Administration of Tempol Reduces Chronic Constriction Injury-Induced Neuropathic Pain in Rats by Increasing SOD Activity and Inhibiting NGF Expression","volume":"36","author":"Zhao","year":"2016","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.ibneur.2023.11.007_bib301","doi-asserted-by":"crossref","first-page":"6939","DOI":"10.1039\/D1TB00720C","article-title":"Superoxide dismutase nanozymes: an emerging star for anti-oxidation","volume":"9","author":"Zhao","year":"2021","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.ibneur.2023.11.007_bib302","first-page":"703","article-title":"Changes of complement and oxidative stress parameters in patients with acute cerebral infarction or cerebral hemorrhage and the clinical significance","volume":"19","author":"Zheng","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.ibneur.2023.11.007_bib303","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1152\/physrev.00041.2009","article-title":"Molecular mechanisms and potential therapeutical targets in Huntington\u2019s disease","volume":"90","author":"Zuccato","year":"2010","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ibneur.2023.11.007_bib304","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1039\/D0NJ00487A","article-title":"Imaging of endoplasmic reticulum superoxide anion fluctuation in a liver injury model by a selective two-photon fluorescent probe","volume":"44","author":"Zuo","year":"2020","journal-title":"N. J. Chem."}],"container-title":["IBRO Neuroscience Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667242123022856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667242123022856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T20:05:59Z","timestamp":1723838759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667242123022856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":304,"alternative-id":["S2667242123022856"],"URL":"https:\/\/doi.org\/10.1016\/j.ibneur.2023.11.007","relation":{},"ISSN":["2667-2421"],"issn-type":[{"value":"2667-2421","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Superoxide dismutase and neurological disorders","name":"articletitle","label":"Article Title"},{"value":"IBRO Neuroscience Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ibneur.2023.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Ltd on behalf of International Brain Research Organization.","name":"copyright","label":"Copyright"}]}}