{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T16:17:16Z","timestamp":1762273036272,"version":"build-2065373602"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intensive and Critical Care Nursing"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.iccn.2023.103414","type":"journal-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T01:44:47Z","timestamp":1676684687000},"page":"103414","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Determination of microbial contamination on the outer surface of needleless connectors before and after disinfection"],"prefix":"10.1016","volume":"77","author":[{"given":"Ay\u015fe","family":"Akb\u0131y\u0131k","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Aksun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.iccn.2023.103414_b0005","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/cid\/ciu239","article-title":"Prevention of central line\u2013associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysis","volume":"59","author":"Blot","year":"2014","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.iccn.2023.103414_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.iccn.2022.103227","article-title":"Healthcare-associated infections in adult intensive care unit patients: changes in epidemiology, diagnosis, prevention and contributions of new technologies","volume":"70","author":"Blot","year":"2022","journal-title":"Intensive Crit. Care Nurs."},{"issue":"4","key":"10.1016\/j.iccn.2023.103414_b0015","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0195-6701(03)00130-0","article-title":"A randomized, prospective clinical trial to assess the potential infection risk associated with the PosiFlow\u00ae needleless connector","volume":"54","author":"Casey","year":"2003","journal-title":"J. Hosp. Infect."},{"key":"10.1016\/j.iccn.2023.103414_b0020","unstructured":"Centers for Disease Control and Prevention (CDC), 2000. National Institute for Occupational Safety and Health.Preventing needlestick injuries in health care settings. www.cdc.gov\/niosh\/(accessed 17 June 2022)."},{"key":"10.1016\/j.iccn.2023.103414_b0025","unstructured":"Centers for Disease Control and Prevention (CDC), 2011. Guidelines for the prevention of intravascular catheter- related infections. https:\/\/www.cdc.gov\/hicpac\/ pdf\/guidelines\/bsi-guidelines-2011.pdf (accessed 17 June 2022)."},{"key":"10.1016\/j.iccn.2023.103414_b0030","unstructured":"Clinical and Laboratory Standards Institute (CLSI), 2018. Performance Standards for antimicrobial susceptibility testing., 28th ed. Suppl. M100, Wayne, Pa, 2018. https:\/\/www.scirp.org\/(S(czeh2tfqyw2orz553k1w0r45))\/reference\/ReferencesPapers.aspx?ReferenceID=2267872 \/(accessed 17 June 2022)."},{"issue":"6","key":"10.1016\/j.iccn.2023.103414_b0035","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1177\/1129729819826036","article-title":"The colonization rate of needleless connector and the impact of disinfection for 15 s on colonization: A prospective pre- and post-intervention study","volume":"20","author":"Devrim","year":"2019","journal-title":"J. Vasc. Access"},{"key":"10.1016\/j.iccn.2023.103414_b0040","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00134-019-05617-x","article-title":"Sustained reduction of catheter-associated bloodstream infections with enhancement of catheter bundle by chlorhexidine dressings over 11 years","volume":"45","author":"Eggimann","year":"2019","journal-title":"Intensive Care Med."},{"issue":"5","key":"10.1016\/j.iccn.2023.103414_b0045","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1086\/516660","article-title":"Incidence of catheter-related bloodstream infection among patients with a needleless, mechanical valve-based intravenous connector in an Australian Hematology-Oncology Unit","volume":"28","author":"Field","year":"2007","journal-title":"Infection Control Hosp Epidemiol."},{"key":"10.1016\/j.iccn.2023.103414_b0050","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1086\/526439","article-title":"Cohort study of the pathogenesis and molecular epidemiology of catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters","volume":"29","author":"Garland","year":"2008","journal-title":"Infect. Control Hosp. Epidemiol."},{"issue":"7","key":"10.1016\/j.iccn.2023.103414_b0055","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1128\/JCM.00459-15","article-title":"Cultures of needleless connectors are useful for ruling out central venous catheter colonization","volume":"53","author":"Guembe","year":"2015","journal-title":"J. Clin. Microbiol."},{"issue":"8","key":"10.1016\/j.iccn.2023.103414_b0060","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s10096-016-2670-4","article-title":"The tegoTM needleless connector for hemodialysis catheters may protect against catheter colonization","volume":"35","author":"Guembe","year":"2016","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"issue":"12","key":"10.1016\/j.iccn.2023.103414_b0065","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.ajic.2019.05.024","article-title":"Microbial colonization of intravascular catheter connectors in hospitalized patients","volume":"47","author":"Hankins","year":"2019","journal-title":"Am. J. Infect. Control"},{"issue":"1","key":"10.1016\/j.iccn.2023.103414_b0070","first-page":"1","article-title":"Infusion nursing standards of practice","volume":"39","author":"Infusion Nurses Society (INS)","year":"2016","journal-title":"J. Infus. Nurs."},{"issue":"12","key":"10.1016\/j.iccn.2023.103414_b0075","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1086\/648418","article-title":"Health care-associated bloodstream infections associated with negative- Or positive-pressure or displacement mechanical valve needleless connectors","volume":"49","author":"Jarvis","year":"2009","journal-title":"Clin. Infect. Dis."},{"issue":"1","key":"10.1016\/j.iccn.2023.103414_b0080","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1086\/499166","article-title":"Increased catheter-related bloodstream infection rates after the introduction of a new mechanical valve intravenous access port","volume":"27","author":"Maragakis","year":"2006","journal-title":"Infect. Control Hosp. Epidemiol."},{"issue":"10008","key":"10.1016\/j.iccn.2023.103414_b0085","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1016\/S0140-6736(15)00244-5","article-title":"Skin antisepsis with chlorhexidine\u2013alcohol versus povidone iodine\u2013alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial","volume":"386","author":"Mimoz","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.iccn.2023.103414_b0090","article-title":"Disinfection of needleless connector hubs: clinical evidence systematic review","volume":"1\u201320","author":"Moureau","year":"2015","journal-title":"Nurs. Res. Pract."},{"issue":"2","key":"10.1016\/j.iccn.2023.103414_b0095","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1378\/chest.128.2.489","article-title":"Risk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patients","volume":"128","author":"Nasia","year":"2005","journal-title":"Chest"},{"issue":"Suppl 1","key":"10.1016\/j.iccn.2023.103414_b0100","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ajic.2011.01.003","article-title":"Healthcare Infection Control Practices Advisory Committee. Guidelines for the prevention of intravascular catheter-related infections","volume":"39","author":"O\u2019Grady","year":"2011","journal-title":"Am. J. Infect. Control"},{"issue":"3","key":"10.1016\/j.iccn.2023.103414_b0105","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1128\/JCM.02220-13","article-title":"Microbial biofilms on needleless connectors for central venous catheters: Comparison of standard and silver-coated devices collected from patients in an acute care hospital","volume":"52","author":"Perez","year":"2014","journal-title":"J. Clin. Microbiol."},{"issue":"30","key":"10.1016\/j.iccn.2023.103414_b0110","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s00134-003-2045-z","article-title":"The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters","volume":"2004","author":"Safdar","year":"2004","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.iccn.2023.103414_b0115","doi-asserted-by":"crossref","DOI":"10.5222\/iksstd.2020.37232","article-title":"Comparison of two needleless connector in preventing catheter related sepsis risk in intensive care unit: prospective cohort study","author":"Sahin","year":"2020","journal-title":"\u0130stanbul Kanuni Sultan S\u00fcleyman T\u0131p Derg."},{"issue":"3","key":"10.1016\/j.iccn.2023.103414_b0120","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ajic.2019.08.020","article-title":"Connectors as a risk factor for blood-associated infections (3-way stopcock and needleless connector): a randomized-experimental study","volume":"48","author":"Sengul","year":"2020","journal-title":"Am. J. Infect. Control"},{"issue":"2","key":"10.1016\/j.iccn.2023.103414_b0125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/jhin.2000.0726","article-title":"A prospective clinical study to investigate the microbial contamination of a needleless connector","volume":"45","author":"Seymou","year":"2000","journal-title":"J. Hosp. Infect."},{"key":"10.1016\/j.iccn.2023.103414_b0130","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ejim.2022.01.040","article-title":"Antiseptic barrier caps in central line-associated bloodstream infections: A systematic review and meta-analysis","volume":"99","author":"Tejada","year":"2022","journal-title":"Eur. J. Intern. Med."}],"container-title":["Intensive and Critical Care Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0964339723000319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0964339723000319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T14:32:14Z","timestamp":1760797934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0964339723000319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":26,"alternative-id":["S0964339723000319"],"URL":"https:\/\/doi.org\/10.1016\/j.iccn.2023.103414","relation":{},"ISSN":["0964-3397"],"issn-type":[{"type":"print","value":"0964-3397"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of microbial contamination on the outer surface of needleless connectors before and after disinfection","name":"articletitle","label":"Article Title"},{"value":"Intensive and Critical Care Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.iccn.2023.103414","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103414"}}