{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T22:18:09Z","timestamp":1781129889037,"version":"3.54.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["10140162210005"],"award-info":[{"award-number":["10140162210005"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Intensive and Critical Care Nursing"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.iccn.2026.104342","type":"journal-article","created":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T03:18:17Z","timestamp":1768706297000},"page":"104342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Practice of nebulization in intensive care unit patients receiving invasive ventilation \u2013 A nationwide survey"],"prefix":"10.1016","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9774-3832","authenticated-orcid":false,"given":"Sarah F.C.","family":"Mugge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"Esmeijer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelies","family":"Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willemke","family":"Stilma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave A.","family":"Dongelmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederique","family":"Paulus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.iccn.2026.104342_b0005","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1007\/s00134-013-2872-5","article-title":"Aerosol therapy during mechanical ventilation: an international survey","volume":"39","author":"Ehrmann","year":"2013","journal-title":"Intensiv Care Med"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0010","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1378\/chest.105.1.237","article-title":"Mucociliary transport in ICU patients","volume":"105","author":"Konrad","year":"1994","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.iccn.2026.104342_b0015","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1378\/chest.06-2065","article-title":"ICU-acquired weakness","volume":"131","author":"Schweickert","year":"2007","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0020","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/s13054-018-2150-6","article-title":"Risk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures","volume":"22","author":"Jaber","year":"2018","journal-title":"Crit Care"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0025","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s13054-017-1710-5","article-title":"Heat and moisture exchangers (HMEs) and heated humidifiers (HHs) in adult critically ill patients: a systematic review, meta-analysis and meta-regression of randomized controlled trials","volume":"21","author":"Vargas","year":"2017","journal-title":"Crit Care"},{"key":"10.1016\/j.iccn.2026.104342_b0030","article-title":"Heat and moisture exchangers versus heated humidifiers for mechanically ventilated adults and children","volume":"9(9):CD004711","author":"Gillies","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.iccn.2026.104342_b0035","article-title":"Humidification during invasive and non-invasive ventilation: A starting tool kit for correct setting","volume":"12","author":"Re","year":"2024","journal-title":"Med Sci"},{"issue":"10","key":"10.1016\/j.iccn.2026.104342_b0040","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1001\/jama.2018.0949","article-title":"Effect of on-demand vs routine nebulization of acetylcysteine with salbutamol on ventilator-free days in intensive care unit patients receiving invasive ventilation: A randomized clinical trial","volume":"319","author":"van Meenen","year":"2018","journal-title":"J Am Med Assoc"},{"issue":"4","key":"10.1016\/j.iccn.2026.104342_b0045","first-page":"309","article-title":"Evaluation of the effect of nebulized N-acetylcysteine on respiratory secretions in mechanically ventilated patients: Randomized clinical trial","volume":"40","author":"Masoompour","year":"2015","journal-title":"Iran J Med Sci"},{"issue":"7","key":"10.1016\/j.iccn.2026.104342_b0050","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.prrv.2006.04.198","article-title":"The pharmacologic approach to airway clearance: mucoactive agents","volume":"2006","author":"Rubin","year":"2006","journal-title":"Paediatr Respir Rev"},{"issue":"9","key":"10.1016\/j.iccn.2026.104342_b0055","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s001010050200","article-title":"The application of n-acetylcysteine as an antioxidant and mucolytic in mechanical ventilation in intensive care patients. A prospective, randomized, placebo-controlled, double-blind study","volume":"44","author":"Konrad","year":"1995","journal-title":"Anaesthesist"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s13613-023-01147-4","article-title":"Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support","volume":"13","author":"Li","year":"2023","journal-title":"Ann Intensive Care"},{"issue":"6","key":"10.1016\/j.iccn.2026.104342_b0065","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1399-6576.2009.01957.x","article-title":"A scandinavian survey of drug administration through inhalation, suctioning and recruitment maneuvers in mechanically ventilated patients","volume":"53","author":"Grivans","year":"2009","journal-title":"Acta Anaesthesiol Scand"},{"issue":"5","key":"10.1016\/j.iccn.2026.104342_b0070","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.jcrc.2014.05.016","article-title":"Cost savings with interventions to reduce aerosolized bronchodilator use in mechanically ventilated patients","volume":"29","author":"Camamo","year":"2014","journal-title":"J Crit Care"},{"issue":"10","key":"10.1016\/j.iccn.2026.104342_b0075","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.4187\/respcare.05803","article-title":"How should aerosols be delivered during invasive mechanical ventilation?","volume":"62","author":"Dhand","year":"2017","journal-title":"Respir Care"},{"key":"10.1016\/j.iccn.2026.104342_b0080","article-title":"Airway care interventions for invasively ventilated critically Ill adults-a Dutch national survey","volume":"10(15):3381","author":"Stilma","year":"2021","journal-title":"J Clin Med"},{"issue":"2","key":"10.1016\/j.iccn.2026.104342_b0085","doi-asserted-by":"crossref","first-page":"154","DOI":"10.4187\/respcare.07520154","article-title":"Utilization of bronchodilators in ventilated patients without obstructive airways disease","volume":"52","author":"Chang","year":"2007","journal-title":"Respir Care"},{"issue":"7","key":"10.1016\/j.iccn.2026.104342_b0090","doi-asserted-by":"crossref","DOI":"10.3390\/jcm13071983","article-title":"Nursing practice of airway care interventions and prone positioning in ICU patients with COVID-19-a Dutch national survey","volume":"13","author":"Esmeijer","year":"2024","journal-title":"J Clin Med"},{"issue":"1748\u20135908","key":"10.1016\/j.iccn.2026.104342_b0095","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1748-5908-7-37","article-title":"Validation of the theoretical domains framework for use in behaviour change and implementation research","volume":"7","author":"Cane","year":"2012","journal-title":"Implement Sci"},{"issue":"8","key":"10.1016\/j.iccn.2026.104342_b0100","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.3390\/life15081292","article-title":"Consensus statements on airway clearance interventions in intubated critically Ill patients\u2014protocol for a Delphi study","volume":"15","author":"Esmeijer","year":"2025","journal-title":"Life"},{"issue":"9596","key":"10.1016\/j.iccn.2026.104342_b0105","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.iccn.2026.104342_b0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.5492\/wjccm.v12.i4.217","article-title":"Improving environmental sustainability of intensive care units: A mini-review","volume":"12","author":"See","year":"2023","journal-title":"World J Crit Care Med"},{"issue":"11","key":"10.1016\/j.iccn.2026.104342_b0115","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1007\/s00134-024-07662-7","article-title":"Environmental sustainability in intensive care: The path forward. an ESICM green paper","volume":"50","author":"De Waele","year":"2024","journal-title":"Intensive Care Med"},{"issue":"10090","key":"10.1016\/j.iccn.2026.104342_b0120","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0140-6736(16)32585-5","article-title":"Evidence for overuse of medical services around the world","volume":"390","author":"Brownlee","year":"2017","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0125","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s43058-023-00498-0","article-title":"Effectiveness of de-implementation strategies for low-value prescribing in secondary care: a systematic review","volume":"4","author":"Dunsmore","year":"2023","journal-title":"Implement Sci Commun"},{"issue":"5","key":"10.1016\/j.iccn.2026.104342_b0130","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/1077558716656970","article-title":"Interventions aimed at reducing use of low-value health services: A systematic review","volume":"74","author":"Colla","year":"2017","journal-title":"Med Care Res Rev"},{"issue":"June","key":"10.1016\/j.iccn.2026.104342_b0135","article-title":"Exploring patients' perceptions of low-value care: An interview study","volume":"111","author":"Verkerk","year":"2023","journal-title":"Patient Educ Couns"},{"issue":"1","key":"10.1016\/j.iccn.2026.104342_b0140","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s13012-021-01173-5","article-title":"A scoping review of de-implementation frameworks and models","volume":"16","author":"Walsh-Bailey","year":"2021","journal-title":"Implement Sci"},{"issue":"5","key":"10.1016\/j.iccn.2026.104342_b0145","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1136\/bmjqs-2019-010060","article-title":"De-implementing wisely: Developing the evidence base to reduce low-value care","volume":"29","author":"Grimshaw","year":"2020","journal-title":"BMJ Qual Saf"},{"issue":"2","key":"10.1016\/j.iccn.2026.104342_b0150","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1136\/bmjqs-2014-003821","article-title":"'Choosing wisely': A growing international campaign","volume":"24","author":"Levinson","year":"2015","journal-title":"BMJ Qual Saf"}],"container-title":["Intensive and Critical Care Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0964339726000108?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0964339726000108?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:33:59Z","timestamp":1778790839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0964339726000108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":30,"alternative-id":["S0964339726000108"],"URL":"https:\/\/doi.org\/10.1016\/j.iccn.2026.104342","relation":{},"ISSN":["0964-3397"],"issn-type":[{"value":"0964-3397","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Practice of nebulization in intensive care unit patients receiving invasive ventilation \u2013 A nationwide survey","name":"articletitle","label":"Article Title"},{"value":"Intensive and Critical Care Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.iccn.2026.104342","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104342"}}