{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:30:58Z","timestamp":1792809058437,"version":"4.5.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","id.theclinics.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Infectious Disease Clinics of North America"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.idc.2015.10.015","type":"journal-article","created":{"date-parts":[[2016,2,18]],"date-time":"2016-02-18T10:27:58Z","timestamp":1455791278000},"page":"125-142","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":120,"title":["Invasive Aspergillosis"],"prefix":"10.1016","volume":"30","author":[{"given":"Jose","family":"Cadena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"George R.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F.","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.idc.2015.10.015_bib1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1086\/525258","article-title":"Treatment of aspergillosis: Clinical practice guidelines of the Infectious Diseases Society of America","volume":"46","author":"Walsh","year":"2008","journal-title":"Clin Infect Dis"},{"issue":"Suppl 1","key":"10.1016\/j.idc.2015.10.015_bib2","doi-asserted-by":"crossref","first-page":"i5","DOI":"10.1093\/jac\/dkq437","article-title":"Risk assessment and prognostic factors for mould-related diseases in immunocompromised patients","volume":"66","author":"Pagano","year":"2011","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.idc.2015.10.015_bib3","series-title":"Pathogenic fungi in humans and animals","first-page":"237","article-title":"Ascomycetes. Aspergillus, fusarium, sporothrix, piedraia, and their relatives","author":"Summerbell","year":"2003"},{"key":"10.1016\/j.idc.2015.10.015_bib4","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3114\/sim.2007.59.05","article-title":"Aspergillus species identification in the clinical setting","volume":"59","author":"Balajee","year":"2007","journal-title":"Stud Mycol"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/00005792-200007000-00006","article-title":"Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group","volume":"79","author":"Patterson","year":"2000","journal-title":"Medicine (Baltimore)"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib6","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1128\/EC.00162-06","article-title":"Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping","volume":"5","author":"Balajee","year":"2006","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.idc.2015.10.015_bib7","series-title":"A\u00a0laboratory guide to common Aspergillus species and their teleomorphs","author":"Klich","year":"1988"},{"issue":"7228","key":"10.1016\/j.idc.2015.10.015_bib8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/nature07528","article-title":"Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus","volume":"457","author":"O'Gorman","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.idc.2015.10.015_bib9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3114\/sim.2007.59.08","article-title":"Nomenclatural considerations in naming species of Aspergillus and its teleomorphs","volume":"59","author":"Pitt","year":"2007","journal-title":"Stud Mycol"},{"issue":"5\u20136","key":"10.1016\/j.idc.2015.10.015_bib10","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s11046-014-9811-z","article-title":"Treatment of infections by cryptic Aspergillus species","volume":"178","author":"Nedel","year":"2014","journal-title":"Mycopathologia"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib11","doi-asserted-by":"crossref","first-page":"4802","DOI":"10.1128\/AAC.00304-11","article-title":"Cryptic species and azole resistance in the Aspergillus niger complex","volume":"55","author":"Howard","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"10.1016\/j.idc.2015.10.015_bib12","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1086\/595846","article-title":"Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: Analysis of multicenter prospective antifungal therapy (path) alliance registry","volume":"48","author":"Neofytos","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.idc.2015.10.015_bib13","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1086\/652761","article-title":"Geoclimatic influences on invasive aspergillosis after hematopoietic stem cell transplantation","volume":"50","author":"Panackal","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib14","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ccm.2009.03.001","article-title":"Fungal infections in hematopoietic stem cell transplantation and solid-organ transplantation\u2013focus on aspergillosis","volume":"30","author":"Nucci","year":"2009","journal-title":"Clin Chest Med"},{"issue":"23","key":"10.1016\/j.idc.2015.10.015_bib15","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1200\/JCO.2008.21.0856","article-title":"Index to predict invasive mold infection in high-risk neutropenic patients based on the area over the neutrophil curve","volume":"27","author":"Nucci","year":"2009","journal-title":"J\u00a0Clin Oncol"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib16","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1034\/j.1399-3062.2000.020105.x","article-title":"Investigation and control of aspergillosis and other filamentous fungal infections in solid organ transplant recipients","volume":"2","author":"Patterson","year":"2000","journal-title":"Transpl Infect Dis"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib17","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1128\/CMR.18.1.44-69.2005","article-title":"Aspergillus infections in transplant recipients","volume":"18","author":"Singh","year":"2005","journal-title":"Clin Microbiol Rev"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib18","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00005792-199903000-00003","article-title":"Invasive aspergillosis in transplant recipients","volume":"78","author":"Paterson","year":"1999","journal-title":"Medicine"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib19","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1164\/rccm.2407004","article-title":"Aspergillosis in \u201cnonimmunocompromised\u201d critically ill patients","volume":"170","author":"Denning","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib20","doi-asserted-by":"crossref","first-page":"971","DOI":"10.3201\/eid1606.100165","article-title":"Invasive aspergillosis after pandemic (H1N1) 2009","volume":"16","author":"Lat","year":"2010","journal-title":"Emerg Infect Dis"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib21","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1164\/rccm.200401-093OC","article-title":"Invasive aspergillosis in critically ill patients without malignancy","volume":"170","author":"Meersseman","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib22","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/QCO.0000000000000043","article-title":"Approach to invasive pulmonary aspergillosis in critically ill patients","volume":"27","author":"Koulenti","year":"2014","journal-title":"Curr Opin Infect Dis"},{"issue":"14","key":"10.1016\/j.idc.2015.10.015_bib23","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1056\/NEJM200104053441415","article-title":"Invasive pulmonary aspergillosis associated with infliximab therapy","volume":"344","author":"Warris","year":"2001","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0002-9343(81)90259-X","article-title":"Fungal infection in chronic granulomatous disease. The importance of the phagocyte in defense against fungi","volume":"71","author":"Cohen","year":"1981","journal-title":"Am J Med"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib25","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/infdis\/jiq102","article-title":"The Y238X stop codon polymorphism in the human beta-glucan receptor dectin-1 and susceptibility to invasive aspergillosis","volume":"203","author":"Chai","year":"2011","journal-title":"J\u00a0Infect Dis"},{"issue":"17","key":"10.1016\/j.idc.2015.10.015_bib26","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1056\/NEJMoa0802629","article-title":"Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation","volume":"359","author":"Bochud","year":"2008","journal-title":"N\u00a0Engl J Med"},{"issue":"Suppl 3","key":"10.1016\/j.idc.2015.10.015_bib27","doi-asserted-by":"crossref","first-page":"S265","DOI":"10.1086\/376526","article-title":"Chronic cavitary and fibrosing pulmonary and pleural aspergillosis: Case series, proposed nomenclature change, and review","volume":"37","author":"Denning","year":"2003","journal-title":"Clin Infect Dis"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib28","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.jaip.2014.08.007","article-title":"Allergic bronchopulmonary aspergillosis","volume":"2","author":"Greenberger","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib29","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00005792-198203000-00005","article-title":"Chronic necrotizing pulmonary aspergillosis: a discrete clinical entity","volume":"61","author":"Binder","year":"1982","journal-title":"Medicine"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1148\/radiology.140.2.7255704","article-title":"\u201cSemi-invasive\u201d pulmonary aspergillosis: a new look at the spectrum of Aspergillus infections of the lung","volume":"140","author":"Gefter","year":"1981","journal-title":"Radiology"},{"issue":"Suppl 1","key":"10.1016\/j.idc.2015.10.015_bib31","doi-asserted-by":"crossref","first-page":"S207","DOI":"10.1080\/13693780400025179","article-title":"The invasive and saprophytic syndromes due to Aspergillus spp","volume":"43","author":"Hope","year":"2005","journal-title":"Med Mycol"},{"issue":"12","key":"10.1016\/j.idc.2015.10.015_bib32","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1086\/657306","article-title":"Efficacy and safety of posaconazole for chronic pulmonary aspergillosis","volume":"51","author":"Felton","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.idc.2015.10.015_bib33","doi-asserted-by":"crossref","first-page":"345","DOI":"10.7326\/0003-4819-100-3-345","article-title":"Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia","volume":"100","author":"Gerson","year":"1984","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib34","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1086\/516480","article-title":"Epidemiology of Aspergillus infections in a large cohort of patients undergoing bone marrow transplantation","volume":"175","author":"Wald","year":"1997","journal-title":"J\u00a0Infect Dis"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib35","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1055\/s-0031-1295715","article-title":"Pulmonary aspergillosis: recent advances","volume":"32","author":"Thompson","year":"2011","journal-title":"Semin Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib36","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1086\/513943","article-title":"Invasive aspergillosis","volume":"26","author":"Denning","year":"1998","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib37","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1200\/JCO.2001.19.1.253","article-title":"Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia","volume":"19","author":"Caillot","year":"2001","journal-title":"J\u00a0Clin Oncol"},{"issue":"Suppl 1","key":"10.1016\/j.idc.2015.10.015_bib38","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.1080\/13693780500064771","article-title":"The radiological spectrum of pulmonary aspergillosis","volume":"43","author":"Greene","year":"2005","journal-title":"Med Mycol"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib39","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/cncr.22738","article-title":"Immune reconstitution inflammatory syndrome in cancer patients with pulmonary aspergillosis recovering from neutropenia: Proof of principle, description, and clinical and research implications","volume":"110","author":"Miceli","year":"2007","journal-title":"Cancer"},{"issue":"12","key":"10.1016\/j.idc.2015.10.015_bib40","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1086\/652768","article-title":"Factors associated with mortality in transplant patients with invasive aspergillosis","volume":"50","author":"Baddley","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib41","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000196477","article-title":"Pulmonary aspergillosis: Early diagnosis improves survival","volume":"62","author":"von Eiff","year":"1995","journal-title":"Respiration"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib42","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1056\/NEJM199103073241003","article-title":"Pulmonary aspergillosis in the acquired immunodeficiency syndrome","volume":"324","author":"Denning","year":"1991","journal-title":"N\u00a0Engl J Med"},{"issue":"3 Pt 1","key":"10.1016\/j.idc.2015.10.015_bib43","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1164\/ajrccm\/144.3_Pt_1.552","article-title":"Ulcerative tracheobronchitis after lung transplantation. A new form of invasive aspergillosis","volume":"144","author":"Kramer","year":"1991","journal-title":"Am Rev Respir Dis"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib44","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/MD.0b013e31826c2ccf","article-title":"Aspergillus tracheobronchitis: Report of 8 cases and review of the literature","volume":"91","author":"Fernandez-Ruiz","year":"2012","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib45","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jaci.2011.11.039","article-title":"Fungal disease of the nose and paranasal sinuses","volume":"129","author":"Thompson","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib46","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s11882-012-0320-1","article-title":"Fungal disease of the nose and sinuses: an updated overview","volume":"13","author":"Chang","year":"2013","journal-title":"Curr Allergy Asthma Rep"},{"issue":"Suppl 1","key":"10.1016\/j.idc.2015.10.015_bib47","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.2500\/ajra.2013.27.3892","article-title":"Chapter 8: invasive fungal rhinosinusitis","volume":"27","author":"Duggal","year":"2013","journal-title":"Am J Rhinol Allergy"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib48","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1001\/jamaophthalmol.2013.1497","article-title":"The mycotic ulcer treatment trial: a randomized trial comparing natamycin vs voriconazole","volume":"131","author":"Prajna","year":"2013","journal-title":"JAMA Ophthalmol"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib49","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/1469-0691.12389","article-title":"Osteomyelitis caused by Aspergillus species: a review of 310 reported cases","volume":"20","author":"Gabrielli","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"10.1016\/j.idc.2015.10.015_bib50","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/01.TP.0000044358.99414.B8","article-title":"The isolation of Aspergillus fumigatus from respiratory tract specimens in heart transplant recipients is highly predictive of invasive aspergillosis","volume":"75","author":"Munoz","year":"2003","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib51","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0002-9343(97)89455-7","article-title":"The use of respiratory-tract cultures in the diagnosis of invasive pulmonary aspergillosis","volume":"100","author":"Horvath","year":"1996","journal-title":"Am J Med"},{"issue":"7","key":"10.1016\/j.idc.2015.10.015_bib52","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1200\/JCO.2002.07.004","article-title":"Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients","volume":"20","author":"Herbrecht","year":"2002","journal-title":"J\u00a0Clin Oncol"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib53","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1182\/blood.V97.6.1604","article-title":"Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: a prospective validation","volume":"97","author":"Maertens","year":"2001","journal-title":"Blood"},{"issue":"Suppl","key":"10.1016\/j.idc.2015.10.015_bib54","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/13693780600904918","article-title":"Issues with galactomannan testing","volume":"44","author":"Verweij","year":"2006","journal-title":"Med Mycol"},{"issue":"12","key":"10.1016\/j.idc.2015.10.015_bib55","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/cid\/ciu673","article-title":"Serum galactomannan-based early detection of invasive aspergillosis in hematology patients receiving effective antimold prophylaxis","volume":"59","author":"Duarte","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib56","doi-asserted-by":"crossref","first-page":"4879","DOI":"10.1128\/AAC.00673-10","article-title":"The initial 96 hours of invasive pulmonary aspergillosis: histopathology, comparative kinetics of galactomannan and (1->3) beta-d-glucan and consequences of delayed antifungal therapy","volume":"54","author":"Hope","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib57","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1128\/JCM.02281-09","article-title":"Prognostic features of galactomannan antigenemia in galactomannan-positive invasive aspergillosis","volume":"48","author":"Koo","year":"2010","journal-title":"J\u00a0Clin Microbiol"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib58","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1086\/647935","article-title":"Bronchoalveolar lavage fluid galactomannan for the diagnosis of invasive pulmonary aspergillosis in patients with hematologic diseases","volume":"49","author":"Maertens","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib59","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1086\/421944","article-title":"Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome","volume":"39","author":"Odabasi","year":"2004","journal-title":"Clin Infect Dis"},{"issue":"8941","key":"10.1016\/j.idc.2015.10.015_bib60","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0140-6736(95)91152-9","article-title":"Plasma (1-->3)-beta-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episodes","volume":"345","author":"Obayashi","year":"1995","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.idc.2015.10.015_bib61","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/cid\/ciu833","article-title":"Serum galactomannan versus a combination of galactomannan and polymerase chain reaction-based Aspergillus DNA detection for early therapy of invasive aspergillosis in high-risk hematological patients: a randomized controlled trial","volume":"60","author":"Aguado","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.idc.2015.10.015_bib62","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1093\/cid\/civ507","article-title":"Aspergillus polymerase chain reaction: Systematic review of evidence for clinical use in comparison with antigen testing","volume":"61","author":"White","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"7","key":"10.1016\/j.idc.2015.10.015_bib63","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1128\/JCM.00667-15","article-title":"Analytical and Clinical Evaluation of the PathoNostics AsperGenius Assay for Detection of Invasive Aspergillosis and Resistance to Azole Antifungal Drugs during Testing of Serum Samples","volume":"53","author":"White","year":"2015","journal-title":"J\u00a0Clin Microbiol"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib64","doi-asserted-by":"crossref","first-page":"e75968","DOI":"10.1371\/journal.pone.0075968","article-title":"SNaPAfu: A novel single nucleotide polymorphism multiplex assay for aspergillus fumigatus direct detection, identification, and genotyping in clinical specimens","volume":"8","author":"Caramalho","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.idc.2015.10.015_bib65","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/QCO.0000000000000203","article-title":"What's new in antifungals: an update on the in-vitro activity and in-vivo efficacy of new and investigational antifungal agents","volume":"28","author":"Wiederhold","year":"2015","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.idc.2015.10.015_bib66","first-page":"43","article-title":"Update on the optimal use of voriconazole for invasive fungal infections","volume":"4","author":"Lat","year":"2011","journal-title":"Infect Drug Resist"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib67","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1056\/NEJMoa020191","article-title":"Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis","volume":"347","author":"Herbrecht","year":"2002","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib68","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1345\/aph.1H671","article-title":"Adverse effects of voriconazole: Analysis of the French Pharmacovigilance Database","volume":"41","author":"Eiden","year":"2007","journal-title":"Ann Pharmacother"},{"issue":"8","key":"10.1016\/j.idc.2015.10.015_bib69","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1093\/cid\/cis599","article-title":"The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: a randomized controlled trial","volume":"55","author":"Park","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib70","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/jac\/dkt508","article-title":"Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology","volume":"69","author":"Ashbee","year":"2014","journal-title":"J\u00a0Antimicrob Chemother"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib71","first-page":"93","article-title":"Impact of intravenous administration of voriconazole in critically ill patients with impaired renal function","volume":"20","author":"Alvarez-Lerma","year":"2008","journal-title":"J\u00a0Chemother"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib72","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1517\/17425250903463878","article-title":"Pharmacology and clinical use of voriconazole","volume":"6","author":"Thompson","year":"2010","journal-title":"Expert Opin Drug Metab Toxicol"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib73","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1056\/NEJMoa061098","article-title":"Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease","volume":"356","author":"Ullmann","year":"2007","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib74","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1056\/NEJMoa061094","article-title":"Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia","volume":"356","author":"Cornely","year":"2007","journal-title":"N\u00a0Engl J Med"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib75","doi-asserted-by":"crossref","first-page":"5503","DOI":"10.1128\/AAC.00802-12","article-title":"Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration","volume":"56","author":"Dolton","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"issue":"Suppl 1","key":"10.1016\/j.idc.2015.10.015_bib76","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2165\/00003495-200161001-00003","article-title":"Pharmacology of itraconazole","volume":"61","author":"De Beule","year":"2001","journal-title":"Drugs"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib77","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1128\/AAC.00705-08","article-title":"Antifungal therapeutic drug monitoring: established and emerging indications","volume":"53","author":"Andes","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib78","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s11046-010-9324-3","article-title":"Isavuconazole: a comprehensive review of spectrum of activity of a new triazole","volume":"170","author":"Thompson","year":"2010","journal-title":"Mycopathologia"},{"key":"10.1016\/j.idc.2015.10.015_bib79","unstructured":"Maertens J, Patterson TF, Rahav G, et\u00a0al. A phase 3 randomized, double-blind trial evaluating isavuconazole vs voriconazole for the primary treatment of invasive fungal disease caused by Aspergillus spp. or other filamentous fungi (SECURE). 24th ECCMID. Barcelona, Spain, 10\u201313 May, 2014."},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib80","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1093\/cid\/civ571","article-title":"Isavuconazole: a new broad-spectrum triazole antifungal agent","volume":"61","author":"Miceli","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib81","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1056\/NEJMct060052","article-title":"Echinocandins for candidemia in adults without neutropenia","volume":"355","author":"Bennett","year":"2006","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib82","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1093\/jac\/dkp355","article-title":"An EORTC phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients","volume":"64","author":"Viscoli","year":"2009","journal-title":"J\u00a0Antimicrob Chemother"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib83","first-page":"410","article-title":"Intravenous micafungin versus voriconazole for chronic pulmonary aspergillosis: a multicenter trial in Japan","volume":"61","author":"Kohno","year":"2010","journal-title":"J\u00a0Infect"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib84","first-page":"337","article-title":"Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis","volume":"53","author":"Denning","year":"2006","journal-title":"J\u00a0Infect"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib85","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1007\/s10096-010-1013-0","article-title":"Efficacy of caspofungin as salvage therapy for invasive aspergillosis compared to standard therapy in a historical cohort","volume":"29","author":"Hiemenz","year":"2010","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.idc.2015.10.015_bib86","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1399-3062.2008.00349.x","article-title":"Micafungin alone or in combination with other systemic antifungal therapies in hematopoietic stem cell transplant recipients with invasive aspergillosis","volume":"11","author":"Kontoyiannis","year":"2009","journal-title":"Transpl Infect Dis"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib87","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/nchembio.1496","article-title":"Amphotericin forms an extramembranous and fungicidal sterol sponge","volume":"10","author":"Anderson","year":"2014","journal-title":"Nat Chem Biol"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib88","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1086\/497126","article-title":"Strategy of following voriconazole versus amphotericin B therapy with other licensed antifungal therapy for primary treatment of invasive aspergillosis: impact of other therapies on outcome","volume":"41","author":"Patterson","year":"2005","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.idc.2015.10.015_bib89","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1086\/319211","article-title":"Mortality and costs of acute renal failure associated with amphotericin B therapy","volume":"32","author":"Bates","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"10","key":"10.1016\/j.idc.2015.10.015_bib90","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1086\/514341","article-title":"Liposomal amphotericin B as initial therapy for invasive mold infection: a randomized trial comparing a high-loading dose regimen with standard dosing (AmBiLoad trial)","volume":"44","author":"Cornely","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.idc.2015.10.015_bib91","doi-asserted-by":"crossref","first-page":"81","DOI":"10.7326\/M13-2508","article-title":"Combination antifungal therapy for invasive aspergillosis: a randomized trial","volume":"162","author":"Marr","year":"2015","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.idc.2015.10.015_bib92","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3201\/eid2106.140717","article-title":"Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus","volume":"21","author":"van der Linden","year":"2015","journal-title":"Emerg Infect Dis"},{"issue":"4","key":"10.1016\/j.idc.2015.10.015_bib93","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.bbmt.2010.04.017","article-title":"Efficacy, safety, and breakthrough infections associated with standard long-term posaconazole antifungal prophylaxis in allogeneic stem cell transplantation recipients","volume":"17","author":"Winston","year":"2011","journal-title":"Biol Blood Marrow Transplant"},{"issue":"11","key":"10.1016\/j.idc.2015.10.015_bib94","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/myc.12213","article-title":"Our 2014 approach to breakthrough invasive fungal infections","volume":"57","author":"Maschmeyer","year":"2014","journal-title":"Mycoses"}],"container-title":["Infectious Disease Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891552015001166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891552015001166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T23:32:02Z","timestamp":1536967922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0891552015001166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":94,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0891552015001166"],"URL":"https:\/\/doi.org\/10.1016\/j.idc.2015.10.015","relation":{},"ISSN":["0891-5520"],"issn-type":[{"value":"0891-5520","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Invasive Aspergillosis","name":"articletitle","label":"Article Title"},{"value":"Infectious Disease Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idc.2015.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}