{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T17:35:35Z","timestamp":1782408935234,"version":"3.54.5"},"reference-count":13,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012781","name":"MSD K.K.","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015731","name":"Bayer Yakuhin","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002975","name":"Dainippon Sumitomo Pharma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002975","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003769","name":"Eisai","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["20fk0210065h0001"],"award-info":[{"award-number":["20fk0210065h0001"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IDCases"],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/j.idcr.2021.e01059","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T10:00:59Z","timestamp":1611741659000},"page":"e01059","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["A case of acute liver failure with echovirus infection diagnosed by a multi-virus real-time PCR system"],"prefix":"10.1016","volume":"23","author":[{"given":"Yuki","family":"Yoshikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michio","family":"Imamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Morio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Yamaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwa","family":"Ando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Kosaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1538-4946","authenticated-orcid":false,"given":"Shinsuke","family":"Uchikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatsue","family":"Fujino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0357-2795","authenticated-orcid":false,"given":"Eisuke","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Yamauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomokazu","family":"Kawaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Tsuge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Hiramatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Nelson","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3409-2156","authenticated-orcid":false,"given":"Hiroshi","family":"Aikata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaji","family":"Wakita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harutaka","family":"Katano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Chayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.idcr.2021.e01059_bib0005","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1002\/hep.22177","article-title":"Acute liver failure: summary of a workshop","volume":"47","author":"Lee","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.idcr.2021.e01059_bib0010","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0140-6736(10)60274-7","article-title":"Acute liver failure","volume":"376","author":"Bernal","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.idcr.2021.e01059_bib0015","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/hepr.12295","article-title":"Classification of the etiologies of acute liver failure in japan: a report by the intractable hepato-biliary diseases study group of japan","volume":"44","author":"Mochida","year":"2014","journal-title":"Hepatol Res"},{"key":"10.1016\/j.idcr.2021.e01059_bib0020","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/rmv.421","article-title":"SEN virus infection","volume":"14","author":"Sagir","year":"2004","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.idcr.2021.e01059_bib0025","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1128\/JCM.02405-12","article-title":"Severe hepatitis associated with an echovirus 18 infection in an immune-compromised adult","volume":"51","author":"Lefterova","year":"2013","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.idcr.2021.e01059_bib0030","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/jmv.21962","article-title":"A novel real\u2010time PCR system for simultaneous detection of human viruses in clinical samples from patients with uncertain diagnoses","volume":"83","author":"Katano","year":"2011","journal-title":"J Med Virol"},{"key":"10.1016\/j.idcr.2021.e01059_bib0035","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1086\/339298","article-title":"Molecular diagnosis of human enteroviruses by phylogeny-based classification by use of the VP4 sequence","volume":"185","author":"Ishiko","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.idcr.2021.e01059_bib0040","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/neup.12171","article-title":"Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections","volume":"35","author":"Kotani","year":"2015","journal-title":"Neuropathology"},{"key":"10.1016\/j.idcr.2021.e01059_bib0045","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/B978-0-444-53488-0.00018-3","article-title":"Enterovirus\/picornavirus infections","volume":"123","author":"Jubelt","year":"2014","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.idcr.2021.e01059_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00148581-200406010-00001","article-title":"Presentation, diagnosis, and management of enterovirus infections in neonates","volume":"6","author":"Abzug","year":"2004","journal-title":"Paediatr Drugs"},{"key":"10.1016\/j.idcr.2021.e01059_bib0055","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/00006454-199705000-00016","article-title":"Severe neonatal echovirus 20 infection characterized by hepatic failure","volume":"16","author":"Verboon-Maciolek","year":"1997","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.idcr.2021.e01059_bib0060","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1046\/j.1442-200x.2004.01857.x","article-title":"Enteroviral hepatitis in children","volume":"46","author":"Kawashima","year":"2004","journal-title":"Pediatr Int"},{"key":"10.1016\/j.idcr.2021.e01059_bib0065","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofx174","article-title":"Acute liver failure due to echovirus 9 associated with persistent B-cell depletion from rituximab","volume":"4","author":"Bajema","year":"2017","journal-title":"Open Forum Infect Dis"}],"container-title":["IDCases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250921000159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250921000159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:04:01Z","timestamp":1761998641000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214250921000159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":13,"alternative-id":["S2214250921000159"],"URL":"https:\/\/doi.org\/10.1016\/j.idcr.2021.e01059","relation":{},"ISSN":["2214-2509"],"issn-type":[{"value":"2214-2509","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A case of acute liver failure with echovirus infection diagnosed by a multi-virus real-time PCR system","name":"articletitle","label":"Article Title"},{"value":"IDCases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idcr.2021.e01059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e01059"}}