{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T14:40:17Z","timestamp":1769352017015,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007833","name":"Hamad Medical Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019779","name":"Qatar National Library","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IDCases"],"published-print":{"date-parts":[[2023]]},"DOI":"10.1016\/j.idcr.2022.e01666","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:13:19Z","timestamp":1671538399000},"page":"e01666","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Otosyphilis: A rare case of reversible hearing loss in a young man with secondary syphilis"],"prefix":"10.1016","volume":"31","author":[{"given":"Enas W.","family":"Sarsak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walid E.","family":"Omer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad A.","family":"Al Bishawi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muna Al","family":"Maslamani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaaeldin Abdulmajed Basher","family":"Abdulmajed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.idcr.2022.e01666_bib1","series-title":"StatPearls","article-title":"Neurosyphilis","author":"Ha","year":"2022"},{"key":"10.1016\/j.idcr.2022.e01666_bib2","doi-asserted-by":"crossref","unstructured":"Arando Lasagabaster M, Otero Guerra L. Syphilis. S\u00edfilis. Enferm Infecc Microbiol Clin (Engl Ed); 37(6); 2019. pp. 398\u2013404. \u3008DOI: 10.1016\/j.eimc.2018.12.009\u3009.","DOI":"10.1016\/j.eimce.2019.03.007"},{"issue":"10078","key":"10.1016\/j.idcr.2022.e01666_bib3","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/S0140-6736(16)32411-4","article-title":"Syphilis [published correction appears in Lancet. 2019 Mar 9;393(10175):986]","volume":"389","author":"Hook","year":"2017","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.idcr.2022.e01666_bib4","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1468-3083.2004.00939.x","article-title":"Otosyphilis: report on six cases","volume":"vol. 18","author":"Klemm","year":"2004","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.idcr.2022.e01666_bib5","doi-asserted-by":"crossref","first-page":"855","DOI":"10.7326\/0003-4819-109-11-855","article-title":"Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment","volume":"109","author":"Lukehart","year":"1988","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.idcr.2022.e01666_bib6","doi-asserted-by":"crossref","first-page":"e90","DOI":"10.1097\/MAO.0b013e3182a3603f","article-title":"Bilateral temporal bone otosyphilis","volume":"35","author":"Kivekas","year":"2014","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.idcr.2022.e01666_bib7","doi-asserted-by":"crossref","first-page":"530","DOI":"10.2340\/0001555563530535","article-title":"Central nervous system involvement in early syphilis. Part II. Correlation between auditory brain stem responses (ABR) and cerebrospinal fluid abnormalities","volume":"63","author":"Lowhagen","year":"1983","journal-title":"Acta Derm-Venereol"},{"key":"10.1016\/j.idcr.2022.e01666_bib8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1017\/S0022215113003575","article-title":"Computed tomography features of luetic osteitis (otosyphilis) of the temporal bone","volume":"128","author":"Ogungbemi","year":"2014","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.idcr.2022.e01666_bib9","unstructured":"Centers for Disease Control Prevention. Sexually transmitted diseases treatment guidelines. Available from: \u3008https:\/\/www.cdc.gov\/std\/treatment\/default.htm\u3009."},{"issue":"1","key":"10.1016\/j.idcr.2022.e01666_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.otohns.2006.08.026","article-title":"Otosyphilis: a review of 85 cases","volume":"136","author":"Yimtae","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.idcr.2022.e01666_bib11","article-title":"Otosyphilis: resurgence of an old disease","author":"Theeuwen","year":"2018","journal-title":"Laryngoscope"},{"key":"10.1016\/j.idcr.2022.e01666_bib12","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1001\/archotol.1966.00760020020008","article-title":"Deafness in congenital syphilis","volume":"83","author":"Karmody","year":"1966","journal-title":"Arch Otolaryngol"},{"issue":"12","key":"10.1016\/j.idcr.2022.e01666_bib13","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1288\/00005537-198312000-00003","article-title":"Otosyphilis and hearing loss: response to penicillin and steroid therapy","volume":"93","author":"Dobbin","year":"1983","journal-title":"Laryngoscope"},{"issue":"1","key":"10.1016\/j.idcr.2022.e01666_bib14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/0019-5154.92666","article-title":"VDRL test and its interpretation","volume":"57","author":"Nayak","year":"2012","journal-title":"Indian J Dermatol"},{"key":"10.1016\/j.idcr.2022.e01666_bib15","doi-asserted-by":"crossref","unstructured":"Kingston M, French P, Goh B, et al. UK national guidelines on the management of syphilis; 19; 2008. pp. 729\u2013740.","DOI":"10.1258\/ijsa.2008.008279"},{"issue":"10","key":"10.1016\/j.idcr.2022.e01666_bib16","article-title":"A rare cause of acute bilateral hearing loss: otosyphilis","volume":"12","author":"Amidou Abdul","year":"2020","journal-title":"Cureus"},{"issue":"11","key":"10.1016\/j.idcr.2022.e01666_bib17","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1288\/00005537-199211000-00010","article-title":"Otosyphilis: a diagnostic and therapeutic dilemma","volume":"102","author":"Gleich","year":"1992","journal-title":"Laryngoscope"},{"key":"10.1016\/j.idcr.2022.e01666_bib18","doi-asserted-by":"crossref","DOI":"10.4081\/cp.2011.e133","article-title":"Unilateral sudden hearing loss due to otosyphilis","volume":"1","author":"de Goffau","year":"2011","journal-title":"Clin Pract"},{"key":"10.1016\/j.idcr.2022.e01666_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1136\/sextrans-2011-050201","article-title":"Doxycycline treatment of otosyphilis with hearing loss","volume":"88","author":"Chotmongkol","year":"2012","journal-title":"Sex Transm Infect"},{"issue":"5","key":"10.1016\/j.idcr.2022.e01666_bib20","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/OLQ.0000000000001155","article-title":"Otosyphilis: a review of the literature","volume":"47","author":"Ramchandani","year":"2020","journal-title":"Sex Transm Dis"}],"container-title":["IDCases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250922002943?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250922002943?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:06:22Z","timestamp":1761998782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214250922002943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":20,"alternative-id":["S2214250922002943"],"URL":"https:\/\/doi.org\/10.1016\/j.idcr.2022.e01666","relation":{},"ISSN":["2214-2509"],"issn-type":[{"value":"2214-2509","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Otosyphilis: A rare case of reversible hearing loss in a young man with secondary syphilis","name":"articletitle","label":"Article Title"},{"value":"IDCases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idcr.2022.e01666","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e01666"}}