{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T03:38:47Z","timestamp":1771817927626,"version":"3.50.1"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T00:00:00Z","timestamp":1725753600000},"content-version":"vor","delay-in-days":251,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IDCases"],"published-print":{"date-parts":[[2024]]},"DOI":"10.1016\/j.idcr.2024.e02081","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T17:56:58Z","timestamp":1725904618000},"page":"e02081","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Efficacy of combination antibiotic therapy including inhaled tobramycin on Burkholderia cepacia pneumonia in a non-cystic fibrosis patient"],"prefix":"10.1016","volume":"38","author":[{"given":"Yasuhito","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyoshi","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichi","family":"Togawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riko","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuki","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsumi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaya","family":"Kawamata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mami","family":"Rikimaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Minemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takefumi","family":"Nikaido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junpei","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenya","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Tanino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.idcr.2024.e02081_bib1","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00139-19","article-title":"Burkholderia cepacia complex bacteria: a feared contamination risk in water-based pharmaceutical products","volume":"33","author":"Tavares","year":"2020","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.idcr.2024.e02081_bib2","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1093\/cid\/cix559","article-title":"A 17-year nationwide study of Burkholderia cepacia complex bloodstream infections among patients in the United States Veterans Health Administration","volume":"65","author":"El Chakhtoura","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.idcr.2024.e02081_bib3","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12890-018-0594-8","article-title":"Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients","volume":"18","author":"Garcia","year":"2018","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.idcr.2024.e02081_bib4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/nrmicro1085","article-title":"The multifarious, multireplicon Burkholderia cepacia complex","volume":"3","author":"Mahenthiralingam","year":"2005","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.idcr.2024.e02081_bib5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.2174\/1871526518666181022112857","article-title":"Burkholderia cepacia complex causing pneumonia in an immunocompetent non-cystic fibrosis patient: case report and review of literature","volume":"20","author":"Datta","year":"2020","journal-title":"Infect Disord Drug Targets"},{"key":"10.1016\/j.idcr.2024.e02081_bib6","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ijantimicag.2017.07.004","article-title":"Clinical characteristics of bacteraemia caused by Burkholderia cepacia complex species and antimicrobial susceptibility of the isolates in a medical centre in Taiwan","volume":"51","author":"Chien","year":"2018","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.idcr.2024.e02081_bib7","article-title":"Cepacia syndrome in a non-cystic fibrosis patient","volume":"2015","author":"Hauser","year":"2015","journal-title":"Case Rep Infect Dis"},{"key":"10.1016\/j.idcr.2024.e02081_bib8","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.2169\/internalmedicine.7170-21","article-title":"Liver cirrhosis complicated by spontaneous bacterial peritonitis caused by the Burkholderia cepacia complex","volume":"60","author":"Hamahata","year":"2021","journal-title":"Intern Med"},{"key":"10.1016\/j.idcr.2024.e02081_bib9","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1086\/519177","article-title":"Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study","volume":"28","author":"Bressler","year":"2007","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.idcr.2024.e02081_bib10","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.ijid.2022.07.004","article-title":"Management of Cepacia syndrome in an immunocompetent non-cystic fibrosis adult patient","volume":"122","author":"Ottu Para","year":"2022","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.idcr.2024.e02081_bib11","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jcf.2008.02.005","article-title":"Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy","volume":"7","author":"Weidmann","year":"2008","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.idcr.2024.e02081_bib12","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1186\/s12931-022-02243-y","article-title":"Effects of long-term tobramycin inhalation solution (TIS) once daily on exacerbation rate in patients with non-cystic fibrosis bronchiectasis","volume":"23","author":"Terpstra","year":"2022","journal-title":"Respir Res"}],"container-title":["IDCases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250924001574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250924001574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T13:04:44Z","timestamp":1733403884000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214250924001574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":12,"alternative-id":["S2214250924001574"],"URL":"https:\/\/doi.org\/10.1016\/j.idcr.2024.e02081","relation":{},"ISSN":["2214-2509"],"issn-type":[{"value":"2214-2509","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of combination antibiotic therapy including inhaled tobramycin on Burkholderia cepacia pneumonia in a non-cystic fibrosis patient","name":"articletitle","label":"Article Title"},{"value":"IDCases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idcr.2024.e02081","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e02081"}}