{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T08:00:32Z","timestamp":1780992032313,"version":"3.54.1"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":60,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IDCases"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.idcr.2026.e02537","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:41:31Z","timestamp":1772498491000},"page":"e02537","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Inflammatory exacerbation of hepatic alveolar echinococcosis during dupilumab therapy: A case report"],"prefix":"10.1016","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4333-4428","authenticated-orcid":false,"given":"Takumu","family":"Hasebe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honami","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitomi","family":"Hasebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Otake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidemi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Sawada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Mizukami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kitada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhito","family":"Sako","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Sakata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayaka","family":"Yuzawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Yokoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.idcr.2026.e02537_bib1","unstructured":"International Office of Epizootics. WHO\/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. L\u2019Oie de Cravan; 2001. 292 p."},{"key":"10.1016\/j.idcr.2026.e02537_bib2","first-page":"1","article-title":"Immunology of alveolar and cystic echinococcosis (AE and CE)","volume":"96","author":"Gottstein","year":"2017","journal-title":"Adv Parasitol"},{"issue":"8","key":"10.1016\/j.idcr.2026.e02537_bib3","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1128\/JCM.40.8.2760-2765.2002","article-title":"Alveolar echinococcosis: characterization of diagnostic antigen Em18 and serological evaluation of recombinant Em18","volume":"40","author":"Sako","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.idcr.2026.e02537_bib4","series-title":"Echinococcosis \u2013 annual epidemiological report for 2020 [Internet]","author":"European Centre for Disease Prevention and Control","year":"2021"},{"key":"10.1016\/j.idcr.2026.e02537_bib5","series-title":"Echinococcosis \u2013 surveillance data, NESID, Japan (1999\u20132018) [Internet]","author":"National Institute of Infectious Diseases (NIID), Japan","year":"2019"},{"issue":"1","key":"10.1016\/j.idcr.2026.e02537_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0011876","article-title":"Human alveolar echinococcosis in Slovakia: epidemiology and genetic diversity of Echinococcus multilocularis, 2000\u20132023","volume":"18","author":"Antolov\u00e1","year":"2024","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"10.1016\/j.idcr.2026.e02537_bib7","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.jamcollsurg.2011.02.007","article-title":"Long-term results of hepatectomy for patients with alveolar echinococcosis: a single-center experience","volume":"212","author":"Kawamura","year":"2011","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.idcr.2026.e02537_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.parint.2005.11.007","article-title":"Survival strategy of Echinococcus multilocularis in the human host","volume":"55","author":"Vuitton","year":"2006","journal-title":"Parasitol Int"},{"key":"10.1016\/j.idcr.2026.e02537_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/735342","article-title":"Parasite-specific IL-17-type cytokine responses and soluble IL-17 receptor levels in alveolar Echinococcosis patients","volume":"2012","author":"Lechner","year":"2012","journal-title":"Clin Dev Immunol"},{"issue":"5","key":"10.1016\/j.idcr.2026.e02537_bib10","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1111\/all.14151","article-title":"Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4R\u03b1 antibody, is required to broadly inhibit type 2 inflammation","volume":"75","author":"Le Floc\u2019h","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.idcr.2026.e02537_bib11","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2147\/JAA.S223402","article-title":"Parasitic (helminthic) infection while on asthma biologic treatment: not everything is what it seems","volume":"12","author":"Tan","year":"2019","journal-title":"J Asthma Allergy"},{"key":"10.1016\/j.idcr.2026.e02537_bib12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3389\/fphar.2023.1276340","article-title":"Parasitic infections related to anti-type 2 immunity monoclonal antibodies: a disproportionality analysis in the food and drug administration\u2019s adverse event reporting system (FAERS)","volume":"14","author":"Pera","year":"2023","journal-title":"Front Pharm"},{"issue":"6","key":"10.1016\/j.idcr.2026.e02537_bib13","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.revmed.2024.04.002","article-title":"Une \u00e9chinococcose alv\u00e9olaire atypique d\u2019\u00e9volution syst\u00e9mique chez une patiente trait\u00e9e par dupilumab","volume":"45","author":"Jacquel","year":"2024","journal-title":"Rev Med Interne"},{"issue":"3","key":"10.1016\/j.idcr.2026.e02537_bib14","first-page":"199","article-title":"Echinococcus multilocularis infection in a patient treated with omalizumab","volume":"23","author":"Skiepko","year":"2013","journal-title":"J Invest Allergol Clin Immunol"}],"container-title":["IDCases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250926000508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214250926000508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T07:44:54Z","timestamp":1780991094000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214250926000508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":14,"alternative-id":["S2214250926000508"],"URL":"https:\/\/doi.org\/10.1016\/j.idcr.2026.e02537","relation":{},"ISSN":["2214-2509"],"issn-type":[{"value":"2214-2509","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inflammatory exacerbation of hepatic alveolar echinococcosis during dupilumab therapy: A case report","name":"articletitle","label":"Article Title"},{"value":"IDCases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.idcr.2026.e02537","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e02537"}}