{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:23:15Z","timestamp":1789827795412,"version":"4.0.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Dental Journal"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.identj.2024.12.013","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T04:24:11Z","timestamp":1735619051000},"page":"32-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["The Burden of Severe Periodontitis in China From 1990 to 2021, With Projections to 2050: A Comprehensive Analysis From The Global Burden of Disease Study 2021"],"prefix":"10.1016","volume":"75","author":[{"given":"Yuyang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinbao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyuan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0001","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/prd.12296","article-title":"The role of the microbiota in periodontal disease","volume":"83","author":"Curtis","year":"2020","journal-title":"Periodontol 2000"},{"issue":"Suppl 1","key":"10.1016\/j.identj.2024.12.013_bib0002","article-title":"Periodontitis: consensus report of workgroup 2 of the 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions","volume":"89","author":"Papapanou","year":"2018","journal-title":"J Periodontol"},{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0003","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/prd.12344","article-title":"Clinical and public health implications of periodontal and systemic diseases: An overview","volume":"83","author":"Genco","year":"2020","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.identj.2024.12.013_bib0004","doi-asserted-by":"crossref","DOI":"10.1111\/jre.13337","article-title":"Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: the global burden of disease 2021 study","author":"Nascimento","year":"2024","journal-title":"J Periodontal Res. Published online"},{"key":"10.1016\/j.identj.2024.12.013_bib0005","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.92895.3","article-title":"Genetic associations between circulating immune cells and periodontitis highlight the prospect of systemic immunoregulation in periodontal care","volume":"12","author":"Ye","year":"2024","journal-title":"Elife"},{"issue":"2","key":"10.1016\/j.identj.2024.12.013_bib0006","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/jcpe.13396","article-title":"The prevalence and severity of periodontal disease in Mainland China: Data from the Fourth National Oral Health Survey (2015-2016)","volume":"48","author":"Jiao","year":"2021","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.identj.2024.12.013_bib0007","unstructured":"National Bureau of Statistics of China. Wang Pingping: The total population maintains growth and the level of urbanization steadily improves. 2021. Available: http:\/\/www.stats.gov.cn\/ztjc\/zdtjgz\/zgrkpc\/dqcrkpc\/ggl\/202105\/t20210519_1817693.html."},{"issue":"10440","key":"10.1016\/j.identj.2024.12.013_bib0008","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/S0140-6736(24)00757-8","volume":"403","year":"2024","journal-title":"Lancet."},{"issue":"10258","key":"10.1016\/j.identj.2024.12.013_bib0009","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/S0140-6736(20)30977-6","article-title":"Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019","volume":"396","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.identj.2024.12.013_bib0010","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12974-021-02319-4","article-title":"Global, regional, and national burden of Guillain\u2013Barr\u00e9 syndrome and its underlying causes from 1990 to 2019","volume":"18","author":"Bragazzi","year":"2021","journal-title":"J Neuroinflammation"},{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0011","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1023\/A:1008953201688","article-title":"Partitioning linear trends in age-adjusted rates [published correction appears in Cancer Causes Control 2000 Mar;11(3):288]","volume":"11","author":"Hankey","year":"2000","journal-title":"Cancer Causes Control"},{"issue":"10","key":"10.1016\/j.identj.2024.12.013_bib0012","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/cac2.12197","article-title":"Cancer incidence, mortality, and burden in China: a time-trend analysis and comparison with the United States and United Kingdom based on the global epidemiological data released in 2020","volume":"41","author":"Qiu","year":"2021","journal-title":"Cancer Commun (Lond)"},{"issue":"8","key":"10.1016\/j.identj.2024.12.013_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2023.103359","article-title":"Temporal trends in the prevalence of autoimmune diseases from 1990 to 2019","volume":"22","author":"Cao","year":"2023","journal-title":"Autoimmun Rev"},{"issue":"3","key":"10.1016\/j.identj.2024.12.013_bib0014","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z","article-title":"Permutation tests for joinpoint regression with applications to cancer rates [published correction appears in Stat Med 2001 Feb 28;20(4):655]","volume":"19","author":"Kim","year":"2000","journal-title":"Stat Med"},{"key":"10.1016\/j.identj.2024.12.013_bib0015","series-title":"Long-term trends in the burden of inflammatory bowel disease in China over three decades: A joinpoint regression and age-period-cohort analysis based on GBD","author":"Zhang","year":"2019"},{"key":"10.1016\/j.identj.2024.12.013_bib0016","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1158\/1055-9965.EPI-11-0421","article-title":"Age-period-cohort models in cancer surveillance research: ready for prime time?","volume":"20","author":"Rosenberg","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.identj.2024.12.013_bib0017","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/000312240807300202","article-title":"Social Inequalities in Happiness in the United States, 1972 to 2004: an age-period-cohort analysis","volume":"73","author":"Yang","year":"2008","journal-title":"Am Sociol Rev"},{"key":"10.1016\/j.identj.2024.12.013_bib0018","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1177\/0962280218801121","article-title":"A new age-period-cohort model for cancer surveillance research","volume":"28","author":"Rosenberg","year":"2019","journal-title":"Stat Methods Med Res"},{"key":"10.1016\/j.identj.2024.12.013_bib0019","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1158\/1055-9965.EPI-14-0300","article-title":"A web tool for age-period-cohort analysis of cancer incidence and mortality rates","volume":"23","author":"Rosenberg","year":"2014","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"3","key":"10.1016\/j.identj.2024.12.013_bib0020","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.kint.2018.04.011","article-title":"Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016","volume":"94","author":"Xie","year":"2018","journal-title":"Kidney Int"},{"key":"10.1016\/j.identj.2024.12.013_bib0021","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s00357-014-9161-z","article-title":"Ward's hierarchical agglomerative clustering method: which algorithms implement ward's criterion?","volume":"31","author":"Murtagh","year":"2014","journal-title":"J Classif"},{"key":"10.1016\/j.identj.2024.12.013_bib0022","doi-asserted-by":"crossref","first-page":"29034","DOI":"10.3402\/gha.v8.29034","article-title":"Promoting health equity: WHO health inequality monitoring at global and national levels","volume":"8","author":"Hosseinpoor","year":"2015","journal-title":"Glob Health Action"},{"issue":"4","key":"10.1016\/j.identj.2024.12.013_bib0023","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1097\/EDE.0000000000000311","article-title":"Relative index of inequality and slope index of inequality: a structured regression framework for estimation","volume":"26","author":"Moreno-Betancur","year":"2015","journal-title":"Epidemiology"},{"issue":"5","key":"10.1016\/j.identj.2024.12.013_bib0024","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/0277-9536(91)90212-U","article-title":"On the measurement of inequalities in health","volume":"33","author":"Wagstaff","year":"1991","journal-title":"Soc Sci Med"},{"key":"10.1016\/j.identj.2024.12.013_bib0025","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.puhe.2022.04.015","article-title":"Global disease burden of COPD from 1990 to 2019 and prediction of future disease burden trend in China","volume":"208","author":"Hu","year":"2022","journal-title":"Public Health"},{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0026","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/prd.12131","article-title":"The aging mouth: differentiating normal aging from disease","volume":"72","author":"Lamster","year":"2016","journal-title":"Periodontol 2000"},{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0027","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/prd.12135","article-title":"Aging, inflammation, immunity and periodontal disease","volume":"72","author":"Ebersole","year":"2016","journal-title":"Periodontol 2000"},{"issue":"6","key":"10.1016\/j.identj.2024.12.013_bib0028","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.amepre.2018.02.014","article-title":"Effect of Smoking on Periodontitis: A Systematic Review and Meta-regression","volume":"54","author":"Leite","year":"2018","journal-title":"Am J Prev Med"},{"issue":"4","key":"10.1016\/j.identj.2024.12.013_bib0029","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/ger.12711","article-title":"Binge drinking and oral health-related quality of life in older adults: Socioeconomic position matters","volume":"40","author":"Oliveira","year":"2023","journal-title":"Gerodontology"},{"issue":"3","key":"10.1016\/j.identj.2024.12.013_bib0030","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/jcpe.13189","article-title":"Periodontitis and cardiovascular diseases: Consensus report","volume":"47","author":"Sanz","year":"2020","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.identj.2024.12.013_bib0031","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2023.1270557","article-title":"Diabetes, periodontitis, and cardiovascular disease: towards equity in diabetes care","volume":"11","author":"Ser\u00f3n","year":"2023","journal-title":"Front Public Health"},{"issue":"10","key":"10.1016\/j.identj.2024.12.013_bib0032","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1902\/jop.2015.140530","article-title":"Associations Between Sex Hormone Levels and Periodontitis in Men: Results From NHANES III","volume":"86","author":"Steffens","year":"2015","journal-title":"J Periodontol"},{"issue":"2","key":"10.1016\/j.identj.2024.12.013_bib0033","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/tobaccocontrol-2020-056444","article-title":"Smoking-related cancer death among men and women in an ageing society (China 2020-2040): a population-based modelling study","volume":"32","author":"Li","year":"2023","journal-title":"Tob Control"},{"issue":"6","key":"10.1016\/j.identj.2024.12.013_bib0034","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1038\/s41591-023-02383-8","article-title":"Alcohol consumption and risks of more than 200 diseases in Chinese men","volume":"29","author":"Im","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.identj.2024.12.013_bib0035","article-title":"Investigating the temporal trends of diabetes disease burden in China during 1990-2019 from a global perspective","volume":"15","author":"Liu","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"10.1016\/j.identj.2024.12.013_bib0036","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1467-789X.2011.00944.x","article-title":"Secular trends in the prevalence of general and abdominal obesity among Chinese adults, 1993-2009","volume":"13","author":"Xi","year":"2012","journal-title":"Obes Rev"},{"key":"10.1016\/j.identj.2024.12.013_bib0037","first-page":"85","article-title":"Summary of the 2015 Chinese adult tobacco survey report","volume":"10","author":"Yan","year":"2016","journal-title":"Chin J Health Manag"},{"issue":"2","key":"10.1016\/j.identj.2024.12.013_bib0038","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1080\/03014460.2019.1707872","article-title":"Age period cohort analysis: a review of what we should and shouldn't do","volume":"47","author":"Bell","year":"2020","journal-title":"Ann Hum Biol"},{"issue":"1","key":"10.1016\/j.identj.2024.12.013_bib0039","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/prd.12338","article-title":"Prevention and management of periodontal diseases and dental caries in the older adults","volume":"84","author":"Al-Nasser","year":"2020","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.identj.2024.12.013_bib0040","unstructured":"World Health Organization. Ageing and health. Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health."},{"issue":"Pt B","key":"10.1016\/j.identj.2024.12.013_bib0041","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.arr.2015.08.003","article-title":"A research agenda for aging in China in the 21st century","volume":"24","author":"Fang","year":"2015","journal-title":"Ageing Res Rev"},{"issue":"10","key":"10.1016\/j.identj.2024.12.013_bib0042","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/JPER.21-0469","article-title":"Global, regional, and national burden of periodontitis from 1990 to 2019: Results from the Global Burden of Disease study 2019","volume":"93","author":"Wu","year":"2022","journal-title":"J Periodontol"},{"key":"10.1016\/j.identj.2024.12.013_bib0043","doi-asserted-by":"crossref","DOI":"10.1016\/j.socscimed.2020.113046","article-title":"Economic growth, income inequality and life expectancy in China","volume":"256","author":"Luo","year":"2020","journal-title":"Soc Sci Med"}],"container-title":["International Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653924016332?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653924016332?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T14:21:43Z","timestamp":1737382903000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020653924016332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0020653924016332"],"URL":"https:\/\/doi.org\/10.1016\/j.identj.2024.12.013","relation":{},"ISSN":["0020-6539"],"issn-type":[{"value":"0020-6539","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Burden of Severe Periodontitis in China From 1990 to 2021, With Projections to 2050: A Comprehensive Analysis From The Global Burden of Disease Study 2021","name":"articletitle","label":"Article Title"},{"value":"International Dental Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.identj.2024.12.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of FDI World Dental Federation.","name":"copyright","label":"Copyright"}]}}